The Prevalence and Correlates of Aberrant Opioid-Related Behaviours among Patients with Sickle Cell Disease in Oman: A cross-sectional study.

Q3 Medicine
Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI:10.18295/2075-0528.2888
Abdullah Al Abulsalam, Khawla Al Kindi, Abdullah Al Ghailani, Hamed Al Sinawi, Naser Al Balushi, Salam Al Kindi, Sathiya P Murthi, Amal Al Fahdi, Mohammed Al Alawi
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引用次数: 0

Abstract

Objectives: This study aimed to assess the prevalence of aberrant opioid-related behaviours (AORB) among patients with sickle cell disease (SCD) in Oman and identify associated risk factors.

Methods: This cross-sectional analytical study was conducted at Sultan Qaboos University Hospital, Muscat, Oman from June to December 2022. Patients with SCD aging 18-65 years old were included and clinically observed for more than 3 months. The Current Opioid Misuse Measure (COMM) was used to evaluate AORB with scores of ≥9 indicating high risk. Demographic and clinical data were collected. The association between AORB and clinical-demographic variables was examined using the Chi-square test.

Results: A total of 144 SCD patients were included in this study; 58.3% of the participants were at high risk of AORB with a mean COMM score of 12.08. A significant relationship was found between perceived lack of family social support and AORB (P <0.001). No significant associations were observed between AORB risk and other studied factors.

Conclusion: This study was the first to document a high prevalence of AORB among SCD patients in Oman. The findings underscore the critical role of family support in mitigating this risk of opioid misuse among this vulnerable population.

阿曼镰状细胞病患者中阿片类药物相关异常行为的流行及其相关因素:一项横断面研究
目的:本研究旨在评估阿曼镰状细胞病(SCD)患者中异常阿片类药物相关行为(AORB)的患病率,并确定相关危险因素。方法:本横断面分析研究于2022年6月至12月在阿曼马斯喀特苏丹卡布斯大学医院进行。纳入年龄18-65岁的SCD患者,临床观察3个月以上。采用现行阿片类药物滥用量表(Current Opioid Misuse Measure, COMM)评估orb,评分≥9分为高危。收集了人口统计学和临床数据。使用卡方检验检验orb与临床人口学变量之间的关系。结果:本研究共纳入144例SCD患者;58.3%的受试者为高危人群,平均COMM评分为12.08。结论:这项研究首次记录了阿曼SCD患者中orb的高患病率。研究结果强调了家庭支持在减轻这一弱势群体滥用阿片类药物风险方面的关键作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.00
自引率
0.00%
发文量
86
审稿时长
7 weeks
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