Supportive Care in Cancer最新文献

{"title":"Oncology's ongoing struggle with evaluating quality of life limiting, treatment-related toxicity.","authors":"Seamus O'Reilly, Siobhan Gaynor, Erica L Mayer","doi":"10.1007/s00520-025-10017-7","DOIUrl":"https://doi.org/10.1007/s00520-025-10017-7","url":null,"abstract":"","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 11","pages":"943"},"PeriodicalIF":3.0,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prophylactic photobiomodulation to reduce oral mucositis in head and neck cancer: an observational study.","authors":"Renata Ferrari, Ana Carolina Felizardo, Lourenço Siqueira, Luana Abreu, Daniele Araújo, Leticia Araujo, Tauana Fernandes, Clara Lopes, Rafaela Peixoto, Bianca Melo, Ana Maria Dias, Ruan Silva, Mariana Tosello Laloni, Bruno Ferrari, Carlos Gil Moreira Ferreira, Eduardo Fregnani, William Nassib William, Cristiane Decat Bergerot","doi":"10.1007/s00520-025-10020-y","DOIUrl":"https://doi.org/10.1007/s00520-025-10020-y","url":null,"abstract":"<p><strong>Purpose: </strong>Oral mucositis (OM) is a common side effect of radiotherapy (RT) and chemoradiotherapy (CRT) in patients with head and neck cancer (HNC). This study investigates the impact of prophylactic photobiomodulation (PBM) on OM incidence in patients with HNC undergoing RT or CRT.</p><p><strong>Methods: </strong>This single-arm, observational study was conducted across multiple cancer centers in Brazil. Baseline assessments included clinical and radiographic dental evaluations, nutritional risk assessment via the Patient-Generated Subjective Global Assessment (PG-SGA), and HPV status determination. All patients received daily prophylactic PBM during RT. OM incidence and severity were assessed daily by a stomatologist using the Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0. Descriptive statistics summarized patient characteristics, and logistic regression identified potential predictors of severe OM (grade 3+).</p><p><strong>Results: </strong>A total of 118 patients with HNC were recruited. The cumulative incidence of OM of any grade was 65.2% (95% CI 60.0-70.4%), with severe OM (Grade 3/4) observed in 28.0% of patients. Risk factors significantly associated with OM included HPV-positive tumor status (OR = 1.65, P = 0.02), concurrent CRT (OR = 1.86, P = 0.002), and nutritional risk (OR = 2.36, P = 0.004). Tumor location also influenced OM risk, with laryngeal cancers showing a lower incidence (OR = 0.72, P = 0.02).</p><p><strong>Conclusion: </strong>Prophylactic PBM appears effective in reducing the incidence and severity of OM among patients with HNC undergoing RT or CRT. These findings support its potential role as a preventive strategy in routine clinical care.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 11","pages":"944"},"PeriodicalIF":3.0,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145293623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing barriers to care for African American men facing prostate cancer: a scoping review of navigation programs.","authors":"Ashley Nicole Smith, Brittany A Campbell, Ghilamichael Andemeskel, Peggy Tahir, Joseph Egbunikeokye, Tisha M Felder, Barbara Cicerelli, Nynikka R Palmer","doi":"10.1007/s00520-025-10009-7","DOIUrl":"10.1007/s00520-025-10009-7","url":null,"abstract":"<p><strong>Purpose: </strong>African American/Black men are disproportionately impacted by prostate cancer (PCa). Patient navigation is an evidence-based approach to address barriers to care, improve access to care and health outcomes, and reduce disparities. This scoping review provides an in-depth examination of navigation programs in PCa care across the cancer continuum, with a focus on African American/Black men in the United States.</p><p><strong>Methods: </strong>We conducted a comprehensive literature search through September 1st, 2023, in PubMed, Embase, Web of Science, and CINAHL Complete, using keywords and index terms within three main themes: PCa, patient navigation, and African American/Black men. We included studies that described or investigated navigation programs/interventions for PCa from screening through survivorship and included at least 30% African American/Black men.</p><p><strong>Results: </strong>Of the 3,556 articles identified, 8 were included. Two articles covered the same navigation program-one reported the protocol and one reported quasi-experimental trial results. All but one study was conducted prior to 2012. The most common navigation activities reported were care coordination, education/information provision, and comfort/emotional support. Navigation improved screening uptake, PCa management, and access to supportive services. Only 3 articles provided information on navigation training. Both clinical (e.g., nurses) and non-clinical (e.g., peers) navigators were reported. Only 1 article discussed cultural tailoring to African American/Black men.</p><p><strong>Conclusion: </strong>Navigation programs in PCa care are beneficial; however, few studies were identified despite disease burden and disparities among African American/Black men. Contemporary navigation programs tailored for African American/Black men are needed to address persistent disparities.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 11","pages":"947"},"PeriodicalIF":3.0,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12521313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145293692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal associations of body composition with sleep problems in the first two years after colorectal cancer treatment.","authors":"Ludovica Margotto, Eline H van Roekel, Marlou-Floor Kenkhuis, Stephanie O Breukink, Eric T P Keulen, Maryska L G Janssen-Heijnen, Ree Meertens, Matty P Weijenberg, Martijn J L Bours","doi":"10.1007/s00520-025-10018-6","DOIUrl":"10.1007/s00520-025-10018-6","url":null,"abstract":"<p><strong>Purpose: </strong>Sleep problems are a frequent concern of colorectal cancer (CRC) survivors. Research on modifiable lifestyle factors that may mitigate sleep problems is sparse. Therefore, we investigated how various body composition parameters are longitudinally associated with sleep problems from 6 weeks up to 24 months post-treatment.</p><p><strong>Methods: </strong>In a prospective cohort of 396 stage I-III CRC survivors, home-based repeated measurements were conducted at diagnosis and at four post-treatment time points. The insomnia scale of the EORTC QLQ-C30 (range: 0-100) was used to measure sleep problems. Anthropometric measurements of adiposity (BMI, fat percentage, waist-hip ratio) and of muscle mass and muscle function (mid-upper arm muscle circumference, handgrip strength) were employed. Linear mixed models were applied to analyze overall longitudinal associations, and hybrid models were used to disentangle inter- and intra-individual components.</p><p><strong>Results: </strong>At 6 weeks post-treatment, 47.0% of participants reported sleep problems and symptom severity was at its highest; a decline was observed thereafter. In confounder-adjusted models, no statistically significant overall longitudinal associations of different body composition parameters with sleep problems were found. Intra-individual analyses revealed that increases in BMI were related to less sleep problems over time (β per 1 kg/m²: -2.8, 95% CI -4.4; -1.2).</p><p><strong>Conclusions: </strong>BMI increases in the first 24 months post-treatment were associated with decreased sleep problems. These findings must be interpreted with caution due to the observational design, yet might suggest a potential link between weight regain and sleep problems among CRC survivors recovering from the physical and mental impact of cancer treatment.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 11","pages":"946"},"PeriodicalIF":3.0,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12521294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145293610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Perceived changes in health behaviours and body weight in response to a cancer diagnosis among individuals living with and beyond breast, prostate, and colorectal cancer in the UK: a cross-sectional study\".","authors":"Yiheng Yao, Ming Qi, Liang Liu","doi":"10.1007/s00520-025-10022-w","DOIUrl":"https://doi.org/10.1007/s00520-025-10022-w","url":null,"abstract":"","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 11","pages":"942"},"PeriodicalIF":3.0,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of supportive care team intervention with nutritional status, adverse events, and treatment status in patients with head and neck cancer undergoing concurrent chemoradiotherapy.","authors":"Akiho Yamashita, Masayuki Kaku, Misato Otsuka, Eriko Matsumoto, Kayo Nakao, Satomi Inoue, Yuki Terada, Mifumi Nakao, Etsushi Tomitaka, Naoki Uemura, Tatsunori Sakai","doi":"10.1007/s00520-025-09965-x","DOIUrl":"https://doi.org/10.1007/s00520-025-09965-x","url":null,"abstract":"<p><strong>Purpose: </strong>At the National Hospital Organization Kumamoto Medical Center, the supportive care team (SCT) provides supportive care to all patients with head and neck cancer (HNC) undergoing concurrent chemoradiotherapy (CCRT). This study aimed to investigate the relationship between SCT intervention and the nutritional status, adverse events, and treatment status of patients with HNC undergoing CCRT.</p><p><strong>Methods: </strong>This study enrolled 40 patients with HNC who underwent CCRT. The primary endpoint was the body weight (BW) loss rate. The secondary endpoints were energy intake, incidence of adverse events, and treatment completion rate.</p><p><strong>Results: </strong>BW loss rate (9.0 ± 5.0 vs. 5.5 ± 3.4%; p = 0.017) was significantly lower in the SCT intervention group (n = 20) than in the non-SCT intervention group (n = 20). The energy intake of radiation therapy (RT) 22-40 Gy (21.0 ± 6.9 vs. 25.4 ± 4.6 kcal/kg ideal BW [IBW]; p = 0.024) and RT 42-60 Gy (22.6 ± 7.2 vs. 26.3 ± 3.8 kcal/kg IBW; p = 0.048) were significantly higher in the SCT intervention group than in the non-SCT intervention group. The incidence of grade 3 or higher oral mucositis was significantly lower in the SCT intervention group than in the non-SCT intervention group (40.0 vs. 10.0%; p = 0.028). The completion rate of CCRT was significantly higher in the SCT intervention group than in the non-SCT intervention group (55.0 vs. 85.0%; p = 0.038).</p><p><strong>Conclusion: </strong>SCT intervention in patients with HNC undergoing CCRT was associated with reduced BW loss rate.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 11","pages":"940"},"PeriodicalIF":3.0,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer patients' perceptions of the meaning in life: a qualitative meta-synthesis.","authors":"Shuman Wang, Wenjie Xu, Zeling Zhang, Aoxing Sun, Wenlong Zhang, Yu Zhang, Yanhong Zhang, Yu Zhu, Hongwei Wan","doi":"10.1007/s00520-025-09948-y","DOIUrl":"https://doi.org/10.1007/s00520-025-09948-y","url":null,"abstract":"<p><strong>Purpose: </strong>Cancer as a major adverse life event may cause suffering for patients and promote meaning-making. However, not all cancer patients can successfully construct meaning in life. A comprehensive and in-depth understanding of cancer patients' perceptions on the meaning in life is important for providing support and inspiration in clinical practice and research. This study used qualitative meta-synthesis to explore cancer patients' perceptions of meaning in life.</p><p><strong>Methods: </strong>A systematic search of 11 English and Chinese databases was conducted from their inception to May 2024. Two researchers independently performed study selection, quality assessment, and data extraction. The Joanna Briggs Institutes (JBI) Critical Appraisal Checklist was used to assess the methodological quality of included studies. A meta-aggregative strategy was employed to synthesize the findings, and the JBI ConQual approach was applied to evaluate the dependability and credibility of the research.</p><p><strong>Results: </strong>A total of 25 eligible studies were included in the meta-synthesis, conducted across 12 countries and involving 730 cancer patients. Three synthesized findings emerged: paths to discovering meaning in life, dynamic meaning-making processes, and challenges in the meaning-making processes. These findings encompassed eight categories: power of support, blooming of self-worth, positive attitude toward facing challenges, gift of experience, normalization of life, seeking illness attribution, finding meaning in the illness, rearranging life priorities, change of value, physical challenges, psychological challenges, and practical challenges.</p><p><strong>Conclusions: </strong>The meaning-making process of cancer patients is a dynamic and multidimensional journey, filled with transformative experiences, while also accompanied by physical, psychological, and practical challenges.</p><p><strong>Prospero registration: </strong>CRD42023447664.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 11","pages":"941"},"PeriodicalIF":3.0,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of baseline hypoalbuminemia on peripheral edema induced by gemcitabine and nab-paclitaxel for pancreatic cancer treatment.","authors":"Yoshitaka Saito, Yoh Takekuma, Yoshito Komatsu, Mitsuru Sugawara","doi":"10.1007/s00520-025-10026-6","DOIUrl":"10.1007/s00520-025-10026-6","url":null,"abstract":"<p><strong>Background: </strong>Gemcitabine (GEM) + nanoparticle albumin-bound paclitaxel (nab-PTX), which is effective in treating pancreatic cancer, frequently induces peripheral edema. Hypoalbuminemia causes generalized peripheral edema and occasionally occurs in patients with cancer, but reports evaluating its interaction with chemotherapy-induced symptoms are lacking. Therefore, we aimed to assess the effect of baseline hypoalbuminemia on peripheral edema following real-world GEM + nab-PTX therapy.</p><p><strong>Methods: </strong>Patients with pancreatic cancer receiving GEM + nab-PTX (n = 212) were divided into a hypoalbuminemia group (serum albumin levels < 3.5 g/dL), and a control group without hypoalbuminemia, and retrospectively evaluated. The primary endpoint was the incidence of grade ≥ 2 peripheral edema within 6 months of treatment initiation.</p><p><strong>Results: </strong>The incidence of grade ≥ 2 peripheral edema within 6 months was 5.7% in the control group and 22.6% in the hypoalbuminemia group, with a significant difference (P = 0.0009), meeting the primary endpoint. The onset time of grade ≥ 2 peripheral edema was significantly earlier in the hypoalbuminemia group than in the control group (P = 0.0003). In contrast, the incidence of all-grade symptoms was 20.1% in the control group and 30.2% in the hypoalbuminemia group, which was not significantly different (P = 0.13). These results were confirmed in the propensity score-matched population. Multivariate Cox proportional hazard regression analyses showed that baseline hypoalbuminemia was a significant risk factor for grade ≥ 2 peripheral edema (adjusted hazard ratio, 3.84; 95% confidence interval, 1.60-9.23; P = 0.003).</p><p><strong>Conclusion: </strong>Our study revealed that patients with baseline hypoalbuminemia who received GEM + nab-PTX therapy for pancreatic cancer developed problematic peripheral edema.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 11","pages":"938"},"PeriodicalIF":3.0,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of systemic inflammation-modified Patient-Generated Subjective Global Assessment in advanced cancers: A large-scale retrospective cohort study.","authors":"Ge Song, Tingting Dai, Yu Min, Haohan Fan, Xuemei Li, Zheran Liu, Qian Yang, Rong Jia, Qiwei Yang, Xiaolin Hu, Yonglin Su, Jitao Zhou","doi":"10.1007/s00520-025-10010-0","DOIUrl":"https://doi.org/10.1007/s00520-025-10010-0","url":null,"abstract":"<p><strong>Background: </strong>A tight association between systemic inflammation and nutritional status has been established. We aim to evaluate the prognostic role of systemic inflammation-modified Patient-Generated Subjective Global Assessment (PG-SGA) criteria in advanced cancers.</p><p><strong>Method: </strong>In this retrospective study, patients with advanced cancers were included from the West China Hospital between Nov 2019 and Sep 2023. Five systemic inflammatory indicators were selected, including the systemic inflammatory index (SII), neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio (LMR), and advanced lung cancer inflammation index (ALI). Nutritional status was evaluated by the PG-SGA criteria. Kaplan-Meier curves, restricted cubic splines (RCS), and Cox regression analyses were used to estimate the effects of inflammation-modified PG-SGA index on the survival of cancer patients.</p><p><strong>Results: </strong>In total, there were 1,065 patients with advanced cancers included in our study. The ALI showed better predictive power in predicting the all-cause mortality of patients with advanced cancers when compared with other systemic inflammation indicators (4th quartile: hazard ratio (HR) = 0.38, 95% confidence interval (CI): 0.29, 0.50, P < 0.001). The ALI-modified PG-SGA index showed the best survival prediction value in patients with advanced cancers, with an AUC of ROC of 0.68 for 365-day mortality, 0.65 for 730-day mortality, and 0.64 for 1,300-day survival prediction, respectively. The C-index (0.626), calibration curves, and decision curve analysis validated the promising predictive accuracy of the PG-SGA/ALI index in predicting the all-cause mortality of patients with advanced cancers. The sensitive analyses also supported the consistent findings as we determined in the main regression.</p><p><strong>Conclusions: </strong>The findings highlight that considering the host systemic inflammation status during the nutrition assessment would bring additional benefits to the survival prediction of advanced cancers. The PG-SGA/ALI index has moderate predictive value compared to the original PG-SGA criteria in the survival prediction of patients with advanced cancers. The PG-SGA/ALI index would be an optimal biomarker for precise survival prediction in cancer patients in clinical practice.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 11","pages":"937"},"PeriodicalIF":3.0,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of message framing on pulmonary rehabilitation behavior for lung cancer surgery patients: Randomized controlled trial.","authors":"Yanyan Liu, Lin Yu, Huiping Cao, Zhuo Yang, Ziyu Wang, Shuai Qiao, Xinxin Shen, Yaodong Ye, Jiao Xie","doi":"10.1007/s00520-025-09994-6","DOIUrl":"https://doi.org/10.1007/s00520-025-09994-6","url":null,"abstract":"<p><strong>Objective: </strong>Pulmonary rehabilitation (PR) improves conditions for lung cancer (LC) surgery patients, but PR behavior is suboptimal. This study investigated the effect of message framing on PR behavior in this population, as this area is underexplored.</p><p><strong>Methods: </strong>A three-arm randomized controlled trial enrolled 102 patients randomly assigned to a gain-framed message (GFM) group (information emphasizing positive outcomes of PR adherence), a loss-framed message (LFM) group (information highlighting negative consequences of non-adherence to PR), or a no-framed message (NFM) group (PR with no framed messages). Data were collected at admission, the day before surgery, the day of discharge, and one month after discharge. Primary outcomes were postoperative exercise adherence and exercise self-efficacy. Secondary outcomes included exercise capacity, dyspnea, anxiety, and depression.</p><p><strong>Results: </strong>The baseline characteristics of the three groups were comparable (P > 0.05). Repeated measures analysis of variance revealed a significant time effect (P < 0.001) and a significant group effect (P < 0.001) for exercise adherence. For exercise self-efficacy, exercise capacity, dyspnea, and anxiety, significant time effects, group effects, and interaction effects were observed (all P < 0.05). However, the interaction effect for depression was not statistically significant (P = 0.109). Both the GFM and LFM groups demonstrated significantly better outcomes across all measures compared to the NFM group (P < 0.05). Furthermore, the GFM group showed significantly greater improvement than the LFM group in all outcomes (P < 0.05).</p><p><strong>Conclusion: </strong>Message frames appear to be a promising communication strategy, with GFM in particular showing potential. When combined with PR, they may have the potential to improve PR behaviors and outcomes among patients undergoing LC surgery. Trial registration number (ChiCTR2300070445) and date of registration (2023-04-12).</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 11","pages":"939"},"PeriodicalIF":3.0,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}