{"title":"Letter to the editor: Evaluation of sarcopenia's relationship with overall survival and treatment toxicity in soft tissue sarcomas.","authors":"Erkan Topkan, Sukran Senyurek, Ugur Selek","doi":"10.1007/s00520-025-09416-7","DOIUrl":"https://doi.org/10.1007/s00520-025-09416-7","url":null,"abstract":"","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 5","pages":"363"},"PeriodicalIF":2.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael K Jones, Andrew Nicklawsky, Jonathan Shortt, Jack Pattee, Victoria Kennerley, Corbin J Eule, Nellowe Candelario, Peter H O'Donnell, Thomas W Flaig
{"title":"Pharmacogenomics of chemotherapy induced peripheral neuropathy using an electronic health record-derived definition: a genome-wide association study.","authors":"Michael K Jones, Andrew Nicklawsky, Jonathan Shortt, Jack Pattee, Victoria Kennerley, Corbin J Eule, Nellowe Candelario, Peter H O'Donnell, Thomas W Flaig","doi":"10.1007/s00520-025-09392-y","DOIUrl":"https://doi.org/10.1007/s00520-025-09392-y","url":null,"abstract":"<p><strong>Purpose: </strong>Prior studies evaluating the genetic predisposition to chemotherapy induced peripheral neuropathy (CIPN) have been limited by small populations due to difficulty with real-world data extraction. This genome-wide association study (GWAS) evaluates the genetic differences between patients who developed CIPN against those unaffected, using an electronic health record (EHR) definition of CIPN.</p><p><strong>Methods: </strong>This study included all patients who received chemotherapy associated with CIPN and had germline genetic data within the biobank at the Colorado Center for Personalized Medicine. CIPN was defined by a new neuropathic pain medication or an ICD-diagnosis of neuropathy after specified chemotherapy initiation. GWAS were stratified by (1) total population, (2) platinum chemotherapy, (3) taxane chemotherapy, and (4) vinca alkaloid chemotherapy. Genes previously associated with CIPN were analyzed within each GWAS.</p><p><strong>Results: </strong>Nine hundred fifteen patients received chemotherapy associated with CIPN, with 528 patients (57%) developing CIPN. Median age at chemotherapy initiation was 60.5 years; female sex (n = 517, 56.5%) and White or Caucasian race (n = 822, 89.8%) were most common. Among single nucleotide polymorphisms (SNPs) that reached suggestive levels of genome-wide significance (p < 1 × 10<sup>-5</sup>), 60 SNPs occurred within 11 genes that may play a role in the development of or protection against CIPN, including RCOR1, CLDN14, TRIM5, and TMC2. No SNPs previously associated with CIPN achieved genome-wide significance in this population.</p><p><strong>Conclusion: </strong>This pharmacogenomic study suggests several genomic loci that may modulate the development of CIPN. This EHR-definition may allow for increased sample sizes and improved statistical power in future genetic studies of CIPN.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 5","pages":"362"},"PeriodicalIF":2.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana S Sousa, Maja Villanueva Garcia, Megan Blanchard, Barbara Daveson, David Currow, Nadia N Khan, David Goldstein, Merran Findlay, Amanda Landers, Meera R Agar
{"title":"Navigating pain and appetite challenges in palliative care for pancreatic cancer: insights from a national, longitudinal consecutive cohort study.","authors":"Mariana S Sousa, Maja Villanueva Garcia, Megan Blanchard, Barbara Daveson, David Currow, Nadia N Khan, David Goldstein, Merran Findlay, Amanda Landers, Meera R Agar","doi":"10.1007/s00520-025-09402-z","DOIUrl":"https://doi.org/10.1007/s00520-025-09402-z","url":null,"abstract":"<p><strong>Purpose: </strong>Pancreatic cancer poses significant challenges in symptom management. Many people have intractable pain and anorexia which is often not amenable to current available options for palliation. This study aims to outline the longitudinal patterns and assess the burden of distress related to pain and appetite experienced by individuals with pancreatic cancer in people referred to Australian palliative care services.</p><p><strong>Methods: </strong>Consecutive national cohort study using point-of-care data on symptom distress in people referred to specialist palliative care services.</p><p><strong>Results: </strong>From 2013 to 2022, information from 20,558 care episodes involving 15,536 people with pancreatic cancer referred to 203 palliative care services nationally were included. Similar numbers of people were admitted to inpatient and community services, with 69% and 60% reporting distress due to pain and appetite, respectively. Distress extended to sleeping (79%, 82%), nausea (83%, 85%), bowels (80%, 83%), breathing (70%, 77%) and fatigue (77%, 77%) for pain and appetite, respectively. Strongest associations were with psychological/spiritual issues (inpatient OR 1.78, 95% CI 1.66-1.90) and pain severity (community OR 1.51, 95% CI 1.42-1.60) for appetite-related distress and pain severity (inpatient OR 1.60, 95% CI 1.49-1.72; community OR 1.35, 95% CI 1.27-1.44) for pain distress. Trends within the cohort revealed increased mild appetite-related distress (+ 10%) and decreased moderate (- 22%) and severe (- 11%) distress, with similar trends for pain.</p><p><strong>Conclusion: </strong>This study underscores prevalent distress in people with pancreatic cancer in Australian palliative care, highlighting the need for optimised referrals and strategies targeting pain severity, appetite-related concerns and psychological and spiritual aspects for improved care outcomes.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 5","pages":"365"},"PeriodicalIF":2.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Woorim Kim, Kyuwoong Kim, Eun Jeong Nam, Su Yeon Kye, Jin Young Choi
{"title":"Trends of hospice utilization in Korea before and after the COVID- 19 pandemic in patients with cancer: an interrupted time series analysis using nationwide data.","authors":"Woorim Kim, Kyuwoong Kim, Eun Jeong Nam, Su Yeon Kye, Jin Young Choi","doi":"10.1007/s00520-025-09432-7","DOIUrl":"https://doi.org/10.1007/s00520-025-09432-7","url":null,"abstract":"<p><strong>Purpose: </strong>The coronavirus disease (COVID- 19) outbreak has impacted hospice care. This study investigated the impact of the pandemic on the rate and average length of hospice utilization in patients with end-stage cancer.</p><p><strong>Methods: </strong>Data from the 2017 to 2022 National Hospice and Palliative Care registry and the cause-of-death statistics were used. The study population included patients with end-stage cancer who received hospice care. Outcome measures were the monthly utilization rate and length of hospice care. An interrupted time series analysis was performed to compare outcome measures before and after the pandemic, set at January 2020. The pre-intervention period was set from August 2017 to December 2019, and the post-intervention period was set from February 2020 to December 2022.</p><p><strong>Results: </strong>The study population included 88,753 individuals. Total hospice utilization rate showed an increasing pre-intervention trend, at a rate of 0.2500 per month (p < 0.0001). The post-intervention trend decreased at a rate of - 0.2634 per month (p < 0.0001). However, the post-intervention slope did not show a significant trend. Total length of utilization showed a decreasing pre-intervention trend, at a rate of - 2.2160 days (p = 0.0001). The post-intervention trend decreased at a rate of - 0.0003 (p < 0.0001), and the post-intervention slope also decreased at a rate of - 0.0001 (p < 0.0001).</p><p><strong>Conclusion: </strong>The pandemic has led to a general decrease in total hospice utilization and average length of utilization. Policies on end-of-life care should be strengthened to ensure adequate provision of hospice care.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 5","pages":"364"},"PeriodicalIF":2.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shuping Zhang, Qingfeng Li, Mingchao Du, Shaohua Hu, Li Zhang, Yanyan Zhang, Jie Zhang, Qiuxia Wang, Qianqian Zhang
{"title":"Experiences and coping strategies related to financial toxicity among frail older colorectal cancer survivors in China: a qualitative study.","authors":"Shuping Zhang, Qingfeng Li, Mingchao Du, Shaohua Hu, Li Zhang, Yanyan Zhang, Jie Zhang, Qiuxia Wang, Qianqian Zhang","doi":"10.1007/s00520-025-09396-8","DOIUrl":"https://doi.org/10.1007/s00520-025-09396-8","url":null,"abstract":"<p><strong>Purpose: </strong>Cancer-related financial toxicity (FT) plays a key role in patients' disease prognosis, well-being, and quality of life. This study aimed to explore the experiences and coping strategies related to FT among frail older colorectal cancer (CRC) survivors in China.</p><p><strong>Methods: </strong>This study adopted a descriptive qualitative approach. Individual interviews were performed with 10 frail older CRC patients at a local hospital from March 2024 to August 2024. Relevant data were analyzed using the Colaizzi's phenomenological analysis.</p><p><strong>Results: </strong>The experiences of FT among frail older CRC patients included (1) insufficient economic income and inadequate medical security; (2) long course of cancer treatment and unaffordability of financial burden; (3) the vulnerability of household economies; and (4) under high psychological pressure and a sense of financial uncertainty. Meanwhile, the coping strategies to mitigate the impacts of FT in this population were as follows: (1) utilizing medical security and insurance policies to reduce FT; (2) financial planning, support, and sharing of responsibilities among family members; and (3) self-psychological adjustment and family members' emotional support.</p><p><strong>Conclusion: </strong>Mitigating FT in frail older CRC survivors is crucial for improving their disease outcomes and quality of life. Understanding the experiences related to FT and identifying relevant coping strategies in this population may contribute to formulating medical and health policies for protecting these patients and their families from the adverse effects of FT. Future studies should be placed on developing effective interventions and providing personalized support for this population to alleviate FT.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 5","pages":"361"},"PeriodicalIF":2.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dexamethasone dose-dependently attenuates docetaxel-induced peripheral neuropathy in breast cancer treatment.","authors":"Ryota Kanno, Yoshitaka Saito, Yoh Takekuma, Masato Takahashi, Tomohiro Oshino, Mitsuru Sugawara","doi":"10.1007/s00520-025-09427-4","DOIUrl":"https://doi.org/10.1007/s00520-025-09427-4","url":null,"abstract":"<p><strong>Purpose: </strong>Peripheral neuropathy is one of the most problematic adverse effects of docetaxel. We previously reported that dexamethasone (DEX) prevents taxane-associated acute pain syndrome (T-APS) in a dose-dependent manner, which might be a partial manifestation of chemotherapy-induced peripheral neuropathy (CIPN), in breast cancer treatment. Therefore, this study examined the dose-dependent prophylactic efficacy of DEX against CIPN.</p><p><strong>Methods: </strong>Female patients with breast cancer receiving docetaxel-containing treatments (75 mg/m<sup>2</sup>) were divided into two groups according to DEX dosage on days 2-4; an 8 mg group (n = 56) and a 4 mg group (n = 28) and retrospectively evaluated. The primary endpoint in this study was defined as the development of grade ≥ 2 CIPN during 4 cycles of the treatment.</p><p><strong>Results: </strong>The incidence of grade ≥ 2 CIPN was 32.1% in the 4 mg group and 10.7% in the 8 mg group and was significantly lower in the 8 mg group (P = 0.03). The incidence of all-grade CIPN was lower in the 8 mg group than in the control group, although the difference was not statistically significant (P = 0.06). Onset time of all-grade and grade ≥ 2 CIPN in the 8 mg group was significantly delayed compared to that in the 4 mg group (P = 0.003 and 0.01, respectively). Additionally, 8 mg/day of DEX was identified as a preventive factor for all-grade CIPN, although the evaluation of grade ≥ 2 symptoms was not possible.</p><p><strong>Conclusion: </strong>Our study found that DEX attenuated docetaxel-induced CIPN in a dose-dependent manner during real-world breast cancer treatment. Further studies are needed to develop better CIPN management strategies.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 5","pages":"360"},"PeriodicalIF":2.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"When East meets West: incorporating Baduanjin, a traditional Chinese Qigong exercise, in supportive care for cancer patients.","authors":"Isaac K S Ng","doi":"10.1007/s00520-025-09423-8","DOIUrl":"https://doi.org/10.1007/s00520-025-09423-8","url":null,"abstract":"","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 5","pages":"359"},"PeriodicalIF":2.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xin Dan, Tang-Lin Chen, Ya-Lin Tian, Yan Huang, Jian-Hua Ren, Ru-Tie Yin, Ya-Lin He
{"title":"Developing and assessing a vomiting-free ward workflow for gynecological patients receiving chemotherapy.","authors":"Xin Dan, Tang-Lin Chen, Ya-Lin Tian, Yan Huang, Jian-Hua Ren, Ru-Tie Yin, Ya-Lin He","doi":"10.1007/s00520-025-09422-9","DOIUrl":"https://doi.org/10.1007/s00520-025-09422-9","url":null,"abstract":"<p><strong>Background: </strong>Chemotherapy-induced nausea and vomiting (CINV) significantly diminishes the quality of life (QoL) for patients undergoing early and late-stage cancer treatments. Despite preventive antiemetic measures, CINV remains a challenge, with limited response rates. CINV adversely affects not only patients' physical health but also their psychological well-being, social interactions, and treatment adherence.</p><p><strong>Objective: </strong>This study aimed to evaluate the impact of a vomiting-free ward initiative on managing CINV and its effects on the psychological well-being and QoL of gynecological cancer patients receiving chemotherapy.</p><p><strong>Method: </strong>In this study, 960 gynecological oncology patients receiving inpatient chemotherapy at a premier obstetrics and gynecology hospital in Sichuan Province were enrolled from January to December 2023. They were evenly divided into intervention and control groups based on their admission dates. Both groups underwent standard care, and the intervention group followed a vomiting-free ward protocol. The effectiveness of this specialized ward was evaluated using the Multinational Association of Supportive Care in Cancer (MASCC) Antiemesis Tool, the Functional Living Index-Emesis (FLIE), and the Hospital Anxiety and Depression Scale (HADS).</p><p><strong>Results: </strong>The intervention group showed significant improvements in the frequency and severity of both acute and delayed CINV compared to the control group. Furthermore, there was a 9.7% and 7.2% decrease in the impact of severe nausea and vomiting on leisure activities and a 6.9% and 8.6% reduction in how moderate to severe nausea and vomiting affected daily living, respectively. The introduction of the vomiting-free ward significantly reduced levels of patient anxiety (t = - 3.148, P < 0.001) and depression (t = - 3.223, P < 0.001) compared to standard care.</p><p><strong>Conclusion: </strong>The implementation of a vomiting-free ward effectively mitigates nausea and vomiting, enhances QoL, and decreases anxiety and depression among gynecological oncology patients. This innovative approach can be integrated into clinical practice, providing valuable insights and guidelines for healthcare professionals.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"358"},"PeriodicalIF":2.8,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omolola Salako, Muhammad Y Habeebu, Paul T Okediji, Adaorah F Enyi, Kehinde S Okunade, Gabriel T Fagbenro, Blossom A Maduafokwa, Oghenekome O Agha, Kamaldeen Abdulraheem, Matthew J Allsop
{"title":"A systematic review and meta-analysis of side effects influenced by non-surgical treatments in African cancer patients.","authors":"Omolola Salako, Muhammad Y Habeebu, Paul T Okediji, Adaorah F Enyi, Kehinde S Okunade, Gabriel T Fagbenro, Blossom A Maduafokwa, Oghenekome O Agha, Kamaldeen Abdulraheem, Matthew J Allsop","doi":"10.1007/s00520-025-09293-0","DOIUrl":"https://doi.org/10.1007/s00520-025-09293-0","url":null,"abstract":"<p><strong>Background: </strong>Cancer treatments such as chemotherapy immunotherapy and radiotherapy are associated with serious adverse effects that affect a patient's physiological functioning and physical appearance, contribute to financial toxicity, reduce quality of life, and increase the risk of treatment discontinuation. This systematic review aims to describe treatment-related side effects associated with non-surgical cancer treatment and clinical factors that influence the severity of side effects experienced among African cancer patients.</p><p><strong>Method: </strong>A systematic search of primary research studies reporting side effects of chemotherapy, radiotherapy, hormone therapy, targeted therapy, and immunotherapy among patients in African countries was undertaken across four databases (Medline (PubMed), ClinicalTrials.gov, Embase, and Cochrane Central Register of Controlled Trials).</p><p><strong>Results: </strong>Of the 7870 identified articles, 51 eligible studies were included . Articles outlined side effects from chemotherapy (n = 31), radiotherapy (n = 6), chemoradiation (n = 9), chemotherapy and targeted therapy (n = 2), and chemotherapy, radiotherapy, and targeted therapy (n = 3). The most prevalent side effects reported were nausea and vomiting (chemotherapy), radiation dermatitis (radiotherapy), neutropenia, and anaemia (chemoradiation). Included studies reported an increased risk of side effects related to combined therapy (i.e., chemoradiation), type of chemotherapy, higher cumulative chemotherapy doses, more frequent treatment cycles, and the presence of comorbidities. Six studies indicated treatment discontinuation arising due to treatment-related side effects.</p><p><strong>Conclusion: </strong>The review highlights the need for cancer care providers to anticipate treatment-related side effects and mitigate them ahead of time, providing necessary prophylactic measures and treatment support.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"356"},"PeriodicalIF":2.8,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Svea Cheng, David Lazris, Christianna Bartel, Krina C Durica, Leeann Chen, Jennifer Fedor, Carissa A Low
{"title":"Exploring what constitutes \"a good day\" for individuals living with advanced cancer: a qualitative interview study.","authors":"Svea Cheng, David Lazris, Christianna Bartel, Krina C Durica, Leeann Chen, Jennifer Fedor, Carissa A Low","doi":"10.1007/s00520-025-09397-7","DOIUrl":"https://doi.org/10.1007/s00520-025-09397-7","url":null,"abstract":"<p><strong>Purpose: </strong>More people are living longer with stage IV cancer due to advances in cancer treatments. However, individuals living with advanced cancer must navigate unique day-to-day challenges and experiences that may be incompletely understood by their health care team. This study aims to better understand the activities, decisions, and experiences that characterize a \"good day\" versus a \"bad day\" for individuals living with advanced cancer.</p><p><strong>Methods: </strong>Twenty participants with stage IV cancer completed semi-structured interviews which involved rating the quality of their day as well as characterizing their experiences and activities during the day. Participants were also asked to describe a theoretical \"very good day\" versus a \"very bad day\" for them personally, as well as advice they would give to another patient with advanced cancer about how to make a day better. Thematic analysis was used to analyze interview transcripts and identify common themes across participants.</p><p><strong>Results: </strong>Interviews revealed that \"good days\" were associated with feeling like oneself before cancer, bringing oneself to engage in activities that bring wellness and joy, feeling connected to others, feeling accomplished, and practicing positive thought patterns. On the other hand, loss of control, uncertainty/unpredictability, disruptive physical symptoms, negative experiences with health care, and inability to reach one's goals were common on \"bad days.\"</p><p><strong>Conclusions: </strong>This qualitative study highlighted common themes in what defines good and bad days living with stage IV cancer. Understanding individual values and priorities may help care teams support people with advanced cancer to optimize their quality of life and functioning and navigate treatment decisions.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"352"},"PeriodicalIF":2.8,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}