Supportive Care in Cancer最新文献

{"title":"A pilot study of a targeted cognitive intervention for cancer survivors.","authors":"Joaquin A Anguera, Karin Snowberg, Steven M Paul, Bruce A Cooper, Kate Oppegaard, Carolyn Harris, Christine Miaskowski","doi":"10.1007/s00520-025-09321-z","DOIUrl":"https://doi.org/10.1007/s00520-025-09321-z","url":null,"abstract":"<p><strong>Purpose: </strong>The primary aims of this four week pilot randomized clinical trial (RCT) involving a targeted cognitive intervention (TCI, n = 25) compared to an expectancy matched active control intervention (EMACI, n = 24), in a sample of cancer survivors were to: determine recruitment and retention rates; evaluate preliminary efficacy to improve three objective measures of cognitive function (i.e., attention, working memory, multi-tasking); evaluate adherence rates for and satisfaction with the interventions, and evaluate for treatment-related adverse events (e.g., nausea, motion sickness).</p><p><strong>Methods: </strong>Cancer survivors were recruited from previous studies through email. Following a screening call, survivors who consented to participate were oriented to the study measures and procedures via Zoom. Survivors were randomized to the TCI or EMACI and mailed an iPad with the software for their specific intervention and the Adaptive Cognitive Evaluation Explorer (ACE-X, the objective measure of cognitive function). Survivors used the intervention for 25 min per day at least 5 days per week. Differences in objective measures of attention, working memory, and multi-tasking were evaluated using multilevel regression analyses.</p><p><strong>Results: </strong>For the sustained attention measure, a significant cross-level interaction was found in favor of the TCI group. While improvements in multi-tasking occurred in both groups, while not statistically significant, the trend was larger for the TCI group. Equally important, in both groups, adherence with the intervention was high and adverse effects were minimal.</p><p><strong>Conclusions: </strong>These preliminary findings provide promising evidence of feasibility, acceptability, and efficacy that warrant evaluation in a RCT with a larger sample of cancer survivors.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"255"},"PeriodicalIF":2.8,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-reported evaluation of oral/dental health in oncology care-a need and opportunity to support medically necessary oral care needs.","authors":"Joel B Epstein, Ira R Parker, Shalya Anand","doi":"10.1007/s00520-025-09316-w","DOIUrl":"https://doi.org/10.1007/s00520-025-09316-w","url":null,"abstract":"","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"256"},"PeriodicalIF":2.8,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Who is your ideal peer mentor? A qualitative study to identify cancer patient preferences for a digital peer support app.","authors":"Loes Knaapen, Andréa Maria Laizner, Kelly Agnew, Xiao Jian Du, Douaa El Abiad, Luc Galarneau, Susie Judd, James Manalad, Ridhi Mittal, Tristan Williams, Brandon Woolfson, Angele Wen, John Kildea","doi":"10.1007/s00520-025-09262-7","DOIUrl":"https://doi.org/10.1007/s00520-025-09262-7","url":null,"abstract":"<p><strong>Purpose: </strong>Peer support can provide many benefits to cancer patients. However, sustained use of one-on-one peer support requires a good match between patient and peer mentor. Using an artificial intelligence (AI) matching algorithm has the potential to improve peer matching by achieving complex, preference-based matching. Therefore, using stakeholder co-design, this study identified patient preferences for peer matching criteria and other features of OpalBuddy, a digital peer support service to be developed within the Opal patient portal.</p><p><strong>Methods: </strong>Patients using the Opal app were recruited, and semi-structured individual interviews were carried out with eight available women cancer patients. Qualitative data analysis followed an iterative and collaborative thematic analysis approach, using computer-assisted software (NVivo).</p><p><strong>Results: </strong>Three themes, with supporting sub-themes, that describe patient preferences for matching with an ideal peer mentor were identified: Theme 1. An ideal mentor can provide support at multiple levels, with sub-themes describing the levels: (A) Sharing illness experiences, (B) Practical information support, (C) Emotional support, (D) Social management coaching. Theme 2. The ideal mentor has similar lived experience, with sub-themes describing the type of lived experience: (A) Similar clinical situation, (B) Similar socio-demographics, (C) Interpersonal affinity. Theme 3. The ideal peer mentor will be supported in their role, with sub-themes describing support options: (A) Formal or informal training, (B) General guidance, (C) Supportive supervision. Finally, based on different support needs (practical vs emotional), it was found that patients had varying, even opposing, expectations from a mentor's interpersonal communication style (solution focused vs good listener).</p><p><strong>Conclusion: </strong>Patient preferences for an ideal peer mentor were identified through semi-structured interviews with a sample of eight women with a diverse set of cancers. Findings will be used to guide further work, including a similar study with men and a pilot study of a digital patient matching service for peer support in the open-source Opal patient portal.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"253"},"PeriodicalIF":2.8,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perturbations in the neuroactive ligand-receptor interaction and renin angiotensin system pathways are associated with cancer-related cognitive impairment.","authors":"Raymond J Chan, Adam Walker, Janette Vardy, Alexandre Chan, Kate Oppegaard, Yvette P Conley, Steven M Paul, Kord M Kober, Carolyn Harris, Joosun Shin, Lisa Morse, Ritu Roy, Adam Olshen, Marilyn J Hammer, Jon D Levine, Christine Miaskowski","doi":"10.1007/s00520-025-09317-9","DOIUrl":"https://doi.org/10.1007/s00520-025-09317-9","url":null,"abstract":"<p><strong>Purpose: </strong>This study reports on the results from our data-driven approach that identified perturbations in neuroactive ligand-receptor interaction and renin-angiotensin system (RAS) pathways in oncology patients with and without self-reported cancer-related cognitive impairment (CRCI).</p><p><strong>Methods: </strong>In a sample of oncology patients receiving chemotherapy (n = 1343), the Attentional Function Index (AFI) was used to assess CRCI. Patients were grouped into low (AFI score of < 5) versus high (AFI score of > 7.5) levels of cognitive function. Gene expression analyses were done using RNA-seq (n = 185) and microarray (n = 158) technologies. Pathway impact analysis was used to evaluate for perturbations in biological pathways associated with self-reported CRCI.</p><p><strong>Results: </strong>The combined pathway impact analysis revealed that the neuroactive ligand-receptor interaction and RAS pathways were significantly perturbed between the patients with low versus high AFI scores.</p><p><strong>Conclusions: </strong>Findings from this study suggest that in addition to inflammatory pathways, numerous mechanisms may contribute to the underlying mechanisms for the development and/or persistence of self-reported CRCI.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"254"},"PeriodicalIF":2.8,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proactive symptom monitoring to initiate timely palliative care for patients with advanced cancer: a randomized controlled trial.","authors":"Grace Meijuan Yang, Yu Ke, Xin Hui Ng, Patricia Soek Hui Neo, Yin Bun Cheung","doi":"10.1007/s00520-025-09311-1","DOIUrl":"https://doi.org/10.1007/s00520-025-09311-1","url":null,"abstract":"<p><strong>Purpose: </strong>To deliver timely palliative care in response to supportive and palliative care needs as they arise, we developed a model called \"Supportive and Palliative care Review Kit in Locations Everywhere\" (SPARKLE), which comprises regular remote symptom monitoring using the Integrated Palliative care Outcome Scale (IPOS); early identification and prompt treatment of palliative care symptoms and concerns identified; and referral to specialist palliative care if follow-up is required.</p><p><strong>Methods: </strong>A prospective randomized controlled trial of SPARKLE versus usual care was conducted among patients with advanced cancers. The primary endpoint was Functional Assessment of Cancer Therapy-General (FACT-G) scores at 16 weeks post randomization.</p><p><strong>Results: </strong>A total of 239 patients were randomized-119 patients to usual care and 120 patients to SPARKLE intervention. There was no significant difference in total FACT-G score (baseline-adjusted difference 0.8, 95% CI - 3.5 to 5.1, p = 0.73). Physical well-being was better in the SPARKLE intervention group compared to the usual care group (baseline-adjusted difference 1.9, 95%CI 0.4 to 3.4, p = 0.01). There were no significant differences in the other domain scores. There were no differences in palliative care referrals, occurrence of emergency department visits, or hospital admissions.</p><p><strong>Conclusion: </strong>Although there was no significant difference in overall quality of life, better physical symptom control could have been achieved through proactive identification and treatment of symptoms and concerns by the SPARKLE nurse. Further studies are warranted to evaluate how various components of palliative care service models impact clinical outcomes.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: NCT04242251. Date of registration: 23 January 2020.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"249"},"PeriodicalIF":2.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shared decision making in routine oncology appointments with Black patients with lung cancer.","authors":"Katarina E AuBuchon, Amanda Khoudary, Jennifer D Rodriguez, Osairys M Billini, Isabella Westervelt, Emily P Taylor, Noelle Newton, Melody Emenyonu, Chul Kim, Irina Veystman, Jennifer Wheeley, Martin Gutierrez, Heather M Derry-Vick, Claire C Conley","doi":"10.1007/s00520-025-09300-4","DOIUrl":"https://doi.org/10.1007/s00520-025-09300-4","url":null,"abstract":"<p><strong>Purpose: </strong>Poor clinician-patient communication may contribute to racialized inequities in cancer symptom burden. Shared decision-making (SDM) enhances clinician-patient communication, and could contribute to health equity for Black patients with cancer. However, research on SDM is limited for Black patients with cancer.</p><p><strong>Methods: </strong>This multi-method longitudinal observational study examined SDM during routine oncology follow-ups for patients with advanced lung cancer. We analyzed SDM reported by clinicians (n = 6), self-identified Black patients with lung cancer (n = 30), and coded from patient visit recordings (n = 20). We described the symptom management conversations, and examined how SDM related to patient satisfaction and symptom severity with two-sided correlations.</p><p><strong>Results: </strong>Most patients (85.0%) asked questions during appointments and discussed cancer-related symptoms (95.0%), most commonly pain/neuropathy (65.0%). Though coded SDM during symptom discussions was low, providers and patients reported high levels of SDM. Coded SDM did not statistically significantly correlate with post-appointment satisfaction (r = -.01, p > .10) or symptom burden (r = .04, p > .10). However, patient-reported SDM did relate to post-appointment satisfaction (r = .72, p = .08) and symptom burden (r = .35, p = .08) one month later.</p><p><strong>Conclusions: </strong>Through detailed multi-method analysis, we found that coded SDM did not correspond to patient and physician-reported SDM during routine oncology appointments. Patient-reported SDM correlated to several better physical and mental health outcomes as well as overall satisfaction a month later. Our findings highlight the complexities of clinician-patient communication and the importance of studying these processes for Black patients with cancer. Future research should develop culturally-relevant methods of assessing SDM with Black patients and understand Black patients' communication needs.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"250"},"PeriodicalIF":2.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early integration or last consultation: in-house palliative care involvement for hospitalized patients in tertiary medicine-a retrospective analysis.","authors":"Nico Bucklar, Markus Schettle, M Feuz, F Däster, Sebastian M Christ, David Blum, Caroline Hertler","doi":"10.1007/s00520-025-09312-0","DOIUrl":"https://doi.org/10.1007/s00520-025-09312-0","url":null,"abstract":"<p><strong>Background: </strong>The importance of timely integration of palliative care has been confirmed over the past years for any patient suffering from a life-threatening or life-limiting disease. Palliative and supportive care increases quality of life of patients and caregivers in both oncological and non-cancer diseases and should therefore be offered on a needs-based approach and throughout the disease trajectory.</p><p><strong>Methods: </strong>We analyzEd all in-patient consultation requests of the leading university hospital in Switzerland in 2019. Sociodemographics, symptoms, and specific requests as well as provided support offers were retrieved from the electronic patient files. Demographic and clinical data was analyzed by descriptive statistics between groups. Overall survival from diagnosis and time from consultation to death was analyzed by means of Kaplan-Meier estimates and log-rank test.</p><p><strong>Results: </strong>We identified 507 in-patient consultation requests from 24 oncological and non-oncological departments in 2019. The final analysis cohort comprised 290 patients, of which 133 women (45.9%). Median overall survival of the population from diagnosis was 21.1 months (CI 15.57-26.72). Median survival from palliative care consultation was 29 days (CI 20.89-37.11), independent of primary diagnosis (p = 0.298) or sex (p = 0.079). A total of 38.9% (N = 140) of consultations were requested concurrently to a tumor-targeted treatment. Palliative care consultations provided more support services than requested (p < 0.001).</p><p><strong>Conclusion: </strong>Our findings underline the persisting late involvement of palliative care services in the disease trajectory, despite being a concurrently consultable and readily available support service to address patient and caregiver needs.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"251"},"PeriodicalIF":2.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of oral mucositis in patients undergoing haploidentical stem cell transplantation with posttransplant cyclophosphamide: marked difference between busulfan and melphalan regimens.","authors":"Saki Ogura, Yoshihiko Soga, Hideaki Fujiwara, Rumi Miura, Ken-Ichi Matsuoka, Yoshinobu Maeda, Takuo Kuboki","doi":"10.1007/s00520-025-09313-z","DOIUrl":"https://doi.org/10.1007/s00520-025-09313-z","url":null,"abstract":"<p><strong>Purpose: </strong>This study was performed to examine the effects of conditioning regimens on oral mucositis in haploidentical (haplo) donor hematopoietic stem cell transplantation (HSCT) with posttransplant cyclophosphamide (PTCy).</p><p><strong>Methods: </strong>Thirty consecutive patients (male, 23; female, 7; 18-68 years, median, 59 years) undergoing haplo-HSCT with PTCy using one of three conditioning regimens-reduced intensity conditioning (RIC)-melphalan (Mel); RIC-Busulfan (Bu); and myeloablative conditioning (MAC)-Bu-were enrolled in this study. Data on the WHO grade of oral mucositis (day - 7 to + 20) were collected retrospectively. The incidences of ulcerative and severe mucositis (Grade 2-4 and Grade 3-4, respectively) were compared between the three groups.</p><p><strong>Results: </strong>Ulcerative mucositis occurred in 0% (0/10) of patients in the RIC-Mel group, 57.1% (4/7) in the RIC-Bu group, and 100% (13/13) in the MAC-Bu group. The differences between the RIC-Mel and RIC-Bu groups and between the RIC-Bu and MAC-Bu groups were significant (all P < 0.05). Severe mucositis occurred in 57.1% (4/7) of patients in the RIC-Bu group and 100% (13/13) of patients in the MAC-Bu group, and the difference was significant (P < 0.05). The rates of ulcerative mucositis (≥ grade 2) and of severe mucositis (≥ grade 3) were significantly higher in the MAC-Bu group than the RIC-Bu group on days 10, 13, 15, and 16 and on days 10, 14, 15, and 16, respectively (all P < 0.05).</p><p><strong>Conclusion: </strong>The risk of oral mucositis in patients undergoing haplo-HSCT with PTCy is highest with the MAC-Bu conditioning regimen, followed by RIC-Bu, and lowest with RIC-Mel.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 4","pages":"252"},"PeriodicalIF":2.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The development and comparative effectiveness of a patient-centered pathology report for breast cancer care: a randomized clinical trial.","authors":"Sara H Javid, Mark R Kilgore, Elizabeth J Austin, Elizabeth U Parker, Rebeca Alvarez, Meghan R Flanagan, Elena G Brewer, Catalina Gibbons, Sarah K Holt, Janie M Lee, Amelia W Donlan, Lauren M DeStefano, John L Gore","doi":"10.1007/s00520-025-09304-0","DOIUrl":"https://doi.org/10.1007/s00520-025-09304-0","url":null,"abstract":"<p><strong>Purpose: </strong>Pathology reports contain complex medical terminology that may be confusing or overwhelming for patients newly diagnosed with breast cancer. We evaluated the effectiveness of patient-centered pathology reports (PCPRs), which translate pathology results into patient-friendly language.</p><p><strong>Methods: </strong>Sixty-six participants newly diagnosed with breast cancer were randomized to receive either a PCPR and standard pathology report (intervention arm) or a standard pathology report alone (control arm). Patients were surveyed at initial pathology disclosure and 1 month later to assess breast cancer knowledge and ratings of decisional confidence, conflict, and self-efficacy for treatment decision-making. Knowledge was assessed for four pathology domains independently.</p><p><strong>Results: </strong>Accuracy of breast cancer knowledge across all domains trended higher for the intervention group compared with the control group (66% vs. 50%, p = 0.11); cancer type and surgical margin status knowledge domains exceeded 75% accuracy for the intervention group. No significant differences between groups were observed for patient-reported ratings of communication, decisional conflict, and decision self-efficacy.</p><p><strong>Conclusions: </strong>PCPRs in lay language appeared to improve patients' knowledge of their breast cancer diagnosis, were acceptable to patients and providers, and have the potential to be broadly applied in an effort to improve patient knowledge and improve the patient experience surrounding a breast cancer diagnosis.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"248"},"PeriodicalIF":2.8,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived changes in health behaviours and body weight in response to a cancer diagnosis among individuals living with and beyond breast, prostate, and colorectal cancer in the UK: a cross-sectional study.","authors":"Francisco Brenes-Castillo, William Goodman, Phillippa Lally, Abi Fisher, Rebecca J Beeken","doi":"10.1007/s00520-025-09305-z","DOIUrl":"10.1007/s00520-025-09305-z","url":null,"abstract":"<p><strong>Purpose: </strong>This study explored perceived changes in health behaviours and body weight following a cancer diagnosis and investigated related sociodemographic and clinical characteristics.</p><p><strong>Methods: </strong>Individuals living with and beyond breast, prostate, or colorectal cancer (N = 5835) completed the 'Health and Lifestyle After Cancer Survey' which explored their perceptions of health behaviour change following a cancer diagnosis. Multinomial logistic regressions were conducted with perceived changes as dependent variables, and sociodemographic and clinical characteristics as independent variables.</p><p><strong>Results: </strong>Approximately half of the participants did not perceive changes in their physical activity, alcohol intake and body weight, and most did not perceive dietary changes. Less than a third of individuals perceived positive health behaviour changes (11.7% increased physical activity, 24.3% healthier diet, and 31.3% decreased alcohol intake), 35.9% perceived decreases in physical activity, and 27.0% perceived increases in body weight, whereas 19.2% perceived decreases in body weight. Individuals with no education, who were unmarried, and with anxiety/depression and pain/discomfort, were more likely to perceive changes in physical activity, body weight, and diet, but in different directions. Participants of younger age were more likely to perceive increases in their physical activity, a healthier diet, and increases in body weight.</p><p><strong>Conclusion: </strong>Following a diagnosis of cancer, a large proportion of individuals perceived that their health behaviours were unchanged. However, some groups of individuals were more likely to perceive positive changes, whereas others were more likely to perceive negative changes, with differences also observed according to the type of health behaviour.</p><p><strong>Implications for cancer survivors: </strong>Participants with no education, who were unmarried, with anxiety/depression and pain/discomfort, may be more at risk of experiencing negative health behaviour changes post-diagnosis. Clinicians should consider targeting health behaviour support to prevent worse outcomes in the long term.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"33 3","pages":"247"},"PeriodicalIF":2.8,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11880087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}