Association of supportive care team intervention with nutritional status, adverse events, and treatment status in patients with head and neck cancer undergoing concurrent chemoradiotherapy.

IF 3 3区医学 Q2 HEALTH CARE SCIENCES & SERVICES

Supportive Care in Cancer Pub Date : 2025-10-14 DOI:10.1007/s00520-025-09965-x

Akiho Yamashita, Masayuki Kaku, Misato Otsuka, Eriko Matsumoto, Kayo Nakao, Satomi Inoue, Yuki Terada, Mifumi Nakao, Etsushi Tomitaka, Naoki Uemura, Tatsunori Sakai

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引用次数: 0

Abstract

Purpose: At the National Hospital Organization Kumamoto Medical Center, the supportive care team (SCT) provides supportive care to all patients with head and neck cancer (HNC) undergoing concurrent chemoradiotherapy (CCRT). This study aimed to investigate the relationship between SCT intervention and the nutritional status, adverse events, and treatment status of patients with HNC undergoing CCRT.

Methods: This study enrolled 40 patients with HNC who underwent CCRT. The primary endpoint was the body weight (BW) loss rate. The secondary endpoints were energy intake, incidence of adverse events, and treatment completion rate.

Results: BW loss rate (9.0 ± 5.0 vs. 5.5 ± 3.4%; p = 0.017) was significantly lower in the SCT intervention group (n = 20) than in the non-SCT intervention group (n = 20). The energy intake of radiation therapy (RT) 22-40 Gy (21.0 ± 6.9 vs. 25.4 ± 4.6 kcal/kg ideal BW [IBW]; p = 0.024) and RT 42-60 Gy (22.6 ± 7.2 vs. 26.3 ± 3.8 kcal/kg IBW; p = 0.048) were significantly higher in the SCT intervention group than in the non-SCT intervention group. The incidence of grade 3 or higher oral mucositis was significantly lower in the SCT intervention group than in the non-SCT intervention group (40.0 vs. 10.0%; p = 0.028). The completion rate of CCRT was significantly higher in the SCT intervention group than in the non-SCT intervention group (55.0 vs. 85.0%; p = 0.038).

Conclusion: SCT intervention in patients with HNC undergoing CCRT was associated with reduced BW loss rate.

查看原文本刊更多论文

支持护理团队干预与同步放化疗头颈癌患者的营养状况、不良事件和治疗状况的关系

目的：在国立医院组织熊本医疗中心，支持性护理团队（SCT）为所有接受同步放化疗（CCRT）的头颈癌（HNC）患者提供支持性护理。本研究旨在探讨SCT干预与接受CCRT的HNC患者营养状况、不良事件和治疗状况的关系。方法：本研究纳入40例接受CCRT治疗的HNC患者。主要终点是体重（BW）损失率。次要终点是能量摄入、不良事件发生率和治疗完成率。结果：SCT干预组（n = 20）的体重损失率（9.0±5.0 vs. 5.5±3.4%;p = 0.017）显著低于非SCT干预组（n = 20）。放射治疗（RT） 22-40 Gy（21.0±6.9 vs. 25.4±4.6 kcal/kg理想体重[IBW]； p = 0.024）和RT 42-60 Gy（22.6±7.2 vs. 26.3±3.8 kcal/kg IBW; p = 0.048）的能量摄入在SCT干预组显著高于非SCT干预组。SCT干预组3级及以上口腔黏膜炎的发生率明显低于非SCT干预组（40.0% vs. 10.0%; p = 0.028）。SCT干预组CCRT完成率显著高于非SCT干预组（55.0% vs. 85.0%, p = 0.038）。结论：行CCRT的HNC患者行SCT干预可降低BW损失率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Supportive Care in Cancer 医学-康复医学

CiteScore

5.70

自引率

9.70%

发文量

751

审稿时长

3 months

期刊介绍： Supportive Care in Cancer provides members of the Multinational Association of Supportive Care in Cancer (MASCC) and all other interested individuals, groups and institutions with the most recent scientific and social information on all aspects of supportive care in cancer patients. It covers primarily medical, technical and surgical topics concerning supportive therapy and care which may supplement or substitute basic cancer treatment at all stages of the disease. Nursing, rehabilitative, psychosocial and spiritual issues of support are also included.