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Tuning the Formation Kinetics of *OOH Intermediate with Hollow Bowl-Like Carbon by Pulsed Electroreduction for Enhanced H2O2 Production
IF 17.1 1区 材料科学
ACS Nano Pub Date : 2025-03-28 DOI: 10.1021/acsnano.5c01453
Ruoxuan Sun, Minghui Zhu, Jie Chen, Lei Yan, Liyi Bai, Jiqiang Ning, Yijun Zhong, Yong Hu
{"title":"Tuning the Formation Kinetics of *OOH Intermediate with Hollow Bowl-Like Carbon by Pulsed Electroreduction for Enhanced H2O2 Production","authors":"Ruoxuan Sun, Minghui Zhu, Jie Chen, Lei Yan, Liyi Bai, Jiqiang Ning, Yijun Zhong, Yong Hu","doi":"10.1021/acsnano.5c01453","DOIUrl":"https://doi.org/10.1021/acsnano.5c01453","url":null,"abstract":"The electrochemical synthesis of hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) via the two-electron oxygen reduction reaction (2e<sup>–</sup> ORR) is a promising alternative to the conventional anthraquinone method. However, due to local alkalinization near the catalyst surface, the restricted oxygen replenishment and insufficient activated water molecule supply limit the formation of the key *OOH intermediate. Herein, a pulsed electrocatalysis approach based on a structurally optimized S/N/O tridoped hollow carbon bowl catalyst has been proposed to overcome this challenge. In an H-type electrolytic cell, the pulsed method achieves a superior H<sub>2</sub>O<sub>2</sub> yield rate of 55.6 mg h<sup>–1</sup> mg<sub>cat.</sub><sup>–1</sup>, approximately 1.6 times higher than the conventional potentiostatic method (34.2 mg h<sup>–1</sup> mg<sub>cat.</sub><sup>–1</sup>), while maintaining the Faradaic efficiency above 94.6%. <i>In situ</i> characterizations, finite element simulations, and density functional theory analyses unveil that the application of pulsed potentials mitigates the local OH<sup>–</sup> concentration, enhances the water activation and proton generation, and facilitates oxygen production within the hollow bowl-like carbon structure. These effects synergistically accelerate the formation kinetics of the *OOH intermediate by the efficient generation of *O<sub>2</sub> and *H<sub>2</sub>O intermediates, leading to superior H<sub>2</sub>O<sub>2</sub> yields. This work develops a strategy to tune catalytic environments for diverse catalytic applications.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"90 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Situ Monitoring of Membrane Protein Dynamics Using High-Throughput Red-Light-Activated Single-Molecule Tracking
IF 17.1 1区 材料科学
ACS Nano Pub Date : 2025-03-28 DOI: 10.1021/acsnano.5c03182
Jinyang Liu, Xuebo Zhang, Bingjie Zhao, Huan Ling, Yanzhong Li, Kuangshi Sun, Song Chen, Yanxin Zhang, Tianli Zhai, Yunxiang Zhang, Fuyou Li, Qian Liu
{"title":"In Situ Monitoring of Membrane Protein Dynamics Using High-Throughput Red-Light-Activated Single-Molecule Tracking","authors":"Jinyang Liu, Xuebo Zhang, Bingjie Zhao, Huan Ling, Yanzhong Li, Kuangshi Sun, Song Chen, Yanxin Zhang, Tianli Zhai, Yunxiang Zhang, Fuyou Li, Qian Liu","doi":"10.1021/acsnano.5c03182","DOIUrl":"https://doi.org/10.1021/acsnano.5c03182","url":null,"abstract":"Single-molecule tracking offers nanometer resolution for studying individual molecule dynamics but is often limited by sparse labeling to avoid signal overlap. We present Red-Light-Activated Single-molecule Tracking (RE-LAST) strategy to address this challenge utilizing a photoactivatable probe, SiR670. SiR670 combines traditional silicon rhodamine with a photocage called SO, quenching fluorescence via photoinduced electron transfer (PET). Red light triggers SiR670 excitation, generating singlet oxygen that oxidizes the SO cage, halting PET and restoring fluorescence. RE-LAST used red light for both activation and imaging, eliminating harmful UV exposure. This method enables high-throughput single-molecule tracking, achieving approximately 9 times more tracks than conventional methods and allowing detailed classification of CD56 membrane protein motion. Furthermore, in situ imaging of single live cells revealed the effects of triplet quencher and oxygen scavenging system (OSS) on membrane protein dynamics. While triplet quenchers like Trolox had minimal impact on protein movement patterns, OSS significantly accelerated protein movement and increased the proportion of mobile proteins. This approach provides a comprehensive method for investigating membrane protein dynamics in living cells, contributing to further developments in cellular and molecular biology.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"92 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low Optical Loss and Bent Waveguides: Crystals of a One-Dimensional Pt1Ag14 Nanocluster
IF 17.1 1区 材料科学
ACS Nano Pub Date : 2025-03-28 DOI: 10.1021/acsnano.5c00359
Chuanjun Zhou, Wei Huang, Kaiyang Kuang, Zhuoyuan Li, Shuang Chen, Yan Kuai, Manzhou Zhu
{"title":"Low Optical Loss and Bent Waveguides: Crystals of a One-Dimensional Pt1Ag14 Nanocluster","authors":"Chuanjun Zhou, Wei Huang, Kaiyang Kuang, Zhuoyuan Li, Shuang Chen, Yan Kuai, Manzhou Zhu","doi":"10.1021/acsnano.5c00359","DOIUrl":"https://doi.org/10.1021/acsnano.5c00359","url":null,"abstract":"Photoluminescent nanoclusters are promising materials for optical waveguides. However, their photon transmission under mechanical stress is very challenging. Here, we report an low-loss metallic nanocluster crystal, [Pt<sub>1</sub>Ag<sub>14</sub>(DPPP)<sub>6</sub>Cl<sub>4</sub>](SbF<sub>6</sub>)<sub>2</sub> (DPPP = 1,3-bis(diphenylphosphino) propane), which exhibits stable optical performance with an optical loss coefficient of 7.15 × 10<sup>–4</sup> dB·μm<sup>–1</sup>─lower than most reported inorganic, organic, and hybrid materials. The Pt<sub>1</sub>Ag<sub>14</sub> crystals maintain excellent optical stability under mechanical deformation, with an optical loss difference of only 0.15 × 10<sup>–3</sup> dB·μm<sup>–1</sup> before and after mechanical stress. Reasonable molecular design endows Pt<sub>1</sub>Ag<sub>14</sub> crystals with robust mechanical flexibility, resulting in their bending radius being smaller than that of nanocluster crystals with similar structures. Structural analysis has shown that multiple π···π, C–H···π, and C–H···F intra- and intermolecular interactions originating from the ligands and between the ligands and counterions ensure molecular and crystal stability under mechanical stress. Metallic nanocluster crystals with low loss and mechanical flexibility generated by rational molecular design offer promising candidates in the fields of active waveguides and flexible electronic materials.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"100 5 Pt 1 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143734395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vertically Integrated Dual-Memtransistor Enabled Reconfigurable Heterosynaptic Sensorimotor Networks and In-Memory Neuromorphic Computing
IF 17.1 1区 材料科学
ACS Nano Pub Date : 2025-03-28 DOI: 10.1021/acsnano.5c00683
Srilagna Sahoo, Abin Varghese, Aniket Sadashiva, Mayank Goyal, Jayatika Sakhuja, Debanjan Bhowmik, Saurabh Lodha
{"title":"Vertically Integrated Dual-Memtransistor Enabled Reconfigurable Heterosynaptic Sensorimotor Networks and In-Memory Neuromorphic Computing","authors":"Srilagna Sahoo, Abin Varghese, Aniket Sadashiva, Mayank Goyal, Jayatika Sakhuja, Debanjan Bhowmik, Saurabh Lodha","doi":"10.1021/acsnano.5c00683","DOIUrl":"https://doi.org/10.1021/acsnano.5c00683","url":null,"abstract":"Neuromorphic in-memory computing requires an area-efficient architecture for seamless and low-latency parallel processing of large volumes of data. Here, we report a compact, vertically integrated/stratified field-effect transistor (VSFET) consisting of a 2D nonferroelectric MoS<sub>2</sub> FET channel stacked on a 2D ferroelectric In<sub>2</sub>Se<sub>3</sub> FET channel. Electrostatic coupling between the ferroelectric and nonferroelectric semiconducting channels results in hysteretic transfer and output characteristics of both FETs. The gate-controlled MoS<sub>2</sub> memtransistor is shown to emulate homosynaptic plasticity behavior with low nonlinearity, low epoch, and high accuracy supervised (ANN─artificial neural network) and unsupervised (SNN─spiking neural network) on-chip learning. Further, simultaneous measurements of the MoS<sub>2</sub> and In<sub>2</sub>Se<sub>3</sub> transistor synapses help to realize complex heterosynaptic cooperation and competition behaviors. These are shown to mimic advanced sensorimotor NN-controlled gill withdrawal reflex sensitization and habituation of a sea mollusk (Aplysia) with ultralow power consumption. Finally, we show logic reconfigurability of the VSFET to realize Boolean gates, thereby adding significant design flexibility for advanced computing technologies.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"24 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143734396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polysaccharide Nanoadjuvants Engineered via Phenotype-Specific Nanoprobe-Assisted Phenotypic Screen Reprogram Macrophage Cell Functions for Cancer and Rheumatoid Arthritis Therapy
IF 17.1 1区 材料科学
ACS Nano Pub Date : 2025-03-28 DOI: 10.1021/acsnano.4c16671
Xuan Mo, Anping Shen, Yicun Han, Li Xu, Jiaqian Miao, Danni Xu, Qing Ji, Yuelong Cao, Guangbo Ge, Xinyuan Zhu, Hongping Deng
{"title":"Polysaccharide Nanoadjuvants Engineered via Phenotype-Specific Nanoprobe-Assisted Phenotypic Screen Reprogram Macrophage Cell Functions for Cancer and Rheumatoid Arthritis Therapy","authors":"Xuan Mo, Anping Shen, Yicun Han, Li Xu, Jiaqian Miao, Danni Xu, Qing Ji, Yuelong Cao, Guangbo Ge, Xinyuan Zhu, Hongping Deng","doi":"10.1021/acsnano.4c16671","DOIUrl":"https://doi.org/10.1021/acsnano.4c16671","url":null,"abstract":"Macrophage plays critical roles in immune-related diseases, acting as a crucial therapeutic target for immunotherapy. Rational design and development of effective therapeutics for macrophage reprogramming are still challenging. Here, we rationally engineered polysaccharide nanoadjuvants to reprogram macrophage functions for enhanced immunotherapy in multiple diseases through a macrophage phenotype-specific nanoprobe (MPSNPr)-assisted high-throughput phenotypic screen. This MPSNPr exhibited high macrophage M1 phenotype specificity because of the formation of H-aggregates on the outer surface and the binding to glucose transporter 1 receptors by the polysaccharide nanocarrier. Based on this MPSNPr, a high-throughput platform was constructed and employed to screen a variety of pharmaceuticals for macrophage reprogramming, being able to identify both pro-inflammatory and anti-inflammatory drug candidates. Polysaccharide nanoadjuvants, Dex-BA and Dex-SAL, were rationally engineered with two potent candidates to amplify macrophage reprogramming efficacy both in vitro and in vivo. Dex-BA significantly inhibited tumor growth by inducing macrophage M1 polarization, dendritic cell maturation, and cytotoxic T cell activation in a mice melanoma model. Dex-SAL alleviated rheumatoid arthritis symptoms with reduced inflammation by reprogramming activated macrophages toward anti-inflammatory phenotype. Our work provides a robust strategy for the rational design and development of effective therapeutics for enhanced macrophage-mediated immunotherapy in diverse diseases.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"33 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanofabrication for Nanophotonics
IF 17.1 1区 材料科学
ACS Nano Pub Date : 2025-03-28 DOI: 10.1021/acsnano.4c10964
Younghwan Yang, Youngsun Jeon, Zhaogang Dong, Joel K. W. Yang, Mahsa Haddadi Moghaddam, Dai-Sik Kim, Dong Kyo Oh, Jihae Lee, Mario Hentschel, Harald Giessen, Dohyun Kang, Gyeongtae Kim, Takuo Tanaka, Yang Zhao, Johannes Bürger, Stefan A. Maier, Haoran Ren, Wooik Jung, Mansoo Choi, Gwangmin Bae, Haomin Chen, Seokwoo Jeon, Jaekyung Kim, Eunji Lee, Hyunjung Kang, Yujin Park, Dang Du Nguyen, Inki Kim, Pablo Cencillo-Abad, Debashis Chanda, Xinxin Jing, Na Liu, Irina V. Martynenko, Tim Liedl, Yuna Kwak, Jwa-Min Nam, Sang-Min Park, Teri W. Odom, Hye-Eun Lee, Ryeong Myeong Kim, Ki Tae Nam, Hyunah Kwon, Hyeon-Ho Jeong, Peer Fischer, Jiwon Yoon, Shin-Hyun Kim, Sangmin Shim, Dasol Lee, Luis A. Pérez, Xiaoyu Qi, Agustin Mihi, Hohyun Keum, Moonsub Shim, Seok Kim, Hanhwi Jang, Yeon Sik Jung, Christian Rossner, Tobias A.F. König, Andreas Fery, Zhiwei Li, Koray Aydin, Chad A. Mirkin, Junhwa Seong, Nara Jeon, Zhiyun Xu, Tian Gu, Juejun Hu, Hyounghan Kwon, Hojoong Jung, Hossein Alijani, Igor Aharonovich, Joohoon Kim, Junsuk Rho
{"title":"Nanofabrication for Nanophotonics","authors":"Younghwan Yang, Youngsun Jeon, Zhaogang Dong, Joel K. W. Yang, Mahsa Haddadi Moghaddam, Dai-Sik Kim, Dong Kyo Oh, Jihae Lee, Mario Hentschel, Harald Giessen, Dohyun Kang, Gyeongtae Kim, Takuo Tanaka, Yang Zhao, Johannes Bürger, Stefan A. Maier, Haoran Ren, Wooik Jung, Mansoo Choi, Gwangmin Bae, Haomin Chen, Seokwoo Jeon, Jaekyung Kim, Eunji Lee, Hyunjung Kang, Yujin Park, Dang Du Nguyen, Inki Kim, Pablo Cencillo-Abad, Debashis Chanda, Xinxin Jing, Na Liu, Irina V. Martynenko, Tim Liedl, Yuna Kwak, Jwa-Min Nam, Sang-Min Park, Teri W. Odom, Hye-Eun Lee, Ryeong Myeong Kim, Ki Tae Nam, Hyunah Kwon, Hyeon-Ho Jeong, Peer Fischer, Jiwon Yoon, Shin-Hyun Kim, Sangmin Shim, Dasol Lee, Luis A. Pérez, Xiaoyu Qi, Agustin Mihi, Hohyun Keum, Moonsub Shim, Seok Kim, Hanhwi Jang, Yeon Sik Jung, Christian Rossner, Tobias A.F. König, Andreas Fery, Zhiwei Li, Koray Aydin, Chad A. Mirkin, Junhwa Seong, Nara Jeon, Zhiyun Xu, Tian Gu, Juejun Hu, Hyounghan Kwon, Hojoong Jung, Hossein Alijani, Igor Aharonovich, Joohoon Kim, Junsuk Rho","doi":"10.1021/acsnano.4c10964","DOIUrl":"https://doi.org/10.1021/acsnano.4c10964","url":null,"abstract":"Nanofabrication, a pivotal technology at the intersection of nanoscale engineering and high-resolution patterning, has substantially advanced over recent decades. This technology enables the creation of nanopatterns on substrates crucial for developing nanophotonic devices and other applications in diverse fields including electronics and biosciences. Here, this mega-review comprehensively explores various facets of nanofabrication focusing on its application in nanophotonics. It delves into high-resolution techniques like focused ion beam and electron beam lithography, methods for 3D complex structure fabrication, scalable manufacturing approaches, and material compatibility considerations. Special attention is given to emerging trends such as the utilization of two-photon lithography for 3D structures and advanced materials like phase change substances and 2D materials with excitonic properties. By highlighting these advancements, the review aims to provide insights into the ongoing evolution of nanofabrication, encouraging further research and application in creating functional nanostructures. This work encapsulates critical developments and future perspectives, offering a detailed narrative on the state-of-the-art in nanofabrication tailored for both new researchers and seasoned experts in the field.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"64 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dynamic Behavior of Liquids on Superspreading Surfaces: From Essential Mechanisms to Applications
IF 17.1 1区 材料科学
ACS Nano Pub Date : 2025-03-27 DOI: 10.1021/acsnano.4c18380
Lu Dai, Zhe Xu, Ye Tian
{"title":"Dynamic Behavior of Liquids on Superspreading Surfaces: From Essential Mechanisms to Applications","authors":"Lu Dai, Zhe Xu, Ye Tian","doi":"10.1021/acsnano.4c18380","DOIUrl":"https://doi.org/10.1021/acsnano.4c18380","url":null,"abstract":"The interaction between liquids and surfaces is a common phenomenon in nature and has attracted extensive scientific attention. Among these interactions, the dynamic behavior of liquids on superspreading surfaces exhibits significant diversity, which can be categorized into four processes: impact, spreading, film formation, and phase transition. Traditional characterization using the equilibrium contact angle (CA) proves insufficient for describing dynamic liquid behaviors. Recent studies introduce superspreading time (ST) and the curve of the superspreading radius versus spreading time (SRST), providing a comprehensive understanding of dynamic spreading processes. This review systematically analyzes the dynamic behaviors of liquids on superspreading surfaces, including their underlying mechanisms and associated influencing factors. Furthermore, we discuss applications of superspreading surfaces by categorizing them into <i>unsteady-state liquid films</i> and <i>steady-state liquid films</i>. The unsteady-state liquid film applications leverage the dynamic processes, such as impact, spreading, and phase transition, to enhance thermal management efficiency, bubble detachment, photothermal conversion, and convective heat transfer. In contrast, the steady-state liquid film applications focus on stable thin film formation for use in areas such as antifouling coatings, drag reduction, biomaterial enhancement, and uniform film fabrication. Finally, we highlight existing challenges in understanding liquid–solid fundamental research and industrial applications. This review provides insights into both the fundamental mechanisms and practical applications of superspreading surfaces, arousing attention in the field of superspreading to strengthen mechanism research and promote practical applications.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"218 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-Volatile Reconfigurable Four-Mode van der Waals Transistors and Transformable Logic Circuits
IF 17.1 1区 材料科学
ACS Nano Pub Date : 2025-03-27 DOI: 10.1021/acsnano.4c16862
Junzhe Kang, Hanwool Lee, Ashwin Tunga, Xiaotong Xu, Ye Lin, Zijing Zhao, Hojoon Ryu, Chun-Chia Tsai, Takashi Taniguchi, Kenji Watanabe, Shaloo Rakheja, Wenjuan Zhu
{"title":"Non-Volatile Reconfigurable Four-Mode van der Waals Transistors and Transformable Logic Circuits","authors":"Junzhe Kang, Hanwool Lee, Ashwin Tunga, Xiaotong Xu, Ye Lin, Zijing Zhao, Hojoon Ryu, Chun-Chia Tsai, Takashi Taniguchi, Kenji Watanabe, Shaloo Rakheja, Wenjuan Zhu","doi":"10.1021/acsnano.4c16862","DOIUrl":"https://doi.org/10.1021/acsnano.4c16862","url":null,"abstract":"Emerging applications in data-intensive computing and circuit security demand logic circuits with high functional density, reconfigurability, and energy efficiency. Here, we demonstrate nonvolatile reconfigurable four-mode field-effect transistors (NVR4M-FETs) based on two-dimensional (2D) MoTe<sub>2</sub> and CuInP<sub>2</sub>S<sub>6</sub> (CIPS), offering both polarity switching and threshold voltage modulation. The device exploits the ferroelectric polarization of CIPS at the source/drain regions to achieve dynamic control over the transistor polarity, enabling transitions between n-type and p-type states through polarization-induced local electrostatic doping. Additionally, multilayer graphene floating gates are incorporated to modulate the threshold voltage, yielding four distinct nonvolatile operating modes: n-type logic, p-type logic, always-on memory, and always-off memory. Leveraging the four-mode property, the NVR4M-FET can function as a one-transistor-per-bit ternary content-addressable memory (TCAM). In addition, we demonstrate the construction of transformable logic gates with 14 distinct logic functions using two NVR4M-FETs and a reconfigurable half a dder/subtractor using three NVR4M-FETs integrated with load resistors. Furthermore, we show that a 2-input look-up table can be achieved with eight NVR4M-FETs compared to 12 transistors using reconfigurable transistors, highlighting the potential of NVR4M-FETs for high-density logic circuits. These results underscore the potential of NVR4M-FETs as essential building blocks for energy-efficient, in-memory computing, and secure hardware applications.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"9 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143713750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Probing the Fluctuating Magnetic Field of Fe-Triazole Spin-Crossover Thin Layers with Nitrogen-Vacancy Centers in Diamond
IF 17.1 1区 材料科学
ACS Nano Pub Date : 2025-03-27 DOI: 10.1021/acsnano.4c16748
Isabel Cardoso Barbosa, Tim Hochdörffer, Juliusz Adam Wolny, Dennis Loenard, Stefan Johansson, Jonas Gutsche, Volker Schünemann, Artur Widera
{"title":"Probing the Fluctuating Magnetic Field of Fe-Triazole Spin-Crossover Thin Layers with Nitrogen-Vacancy Centers in Diamond","authors":"Isabel Cardoso Barbosa, Tim Hochdörffer, Juliusz Adam Wolny, Dennis Loenard, Stefan Johansson, Jonas Gutsche, Volker Schünemann, Artur Widera","doi":"10.1021/acsnano.4c16748","DOIUrl":"https://doi.org/10.1021/acsnano.4c16748","url":null,"abstract":"The magnetic properties of Fe<sup>II</sup> spin-crossover (SCO) complexes can be changed upon temperature variation, often exhibiting thermal hysteresis. Particularly interesting for magnetic-memory applications are thin layers of SCO complexes, where practical magnetic probing techniques are required. While conventional magnetometry on SCO complexes employs cryogenic temperatures, nitrogen-vacancy (NV) centers are quantum magnetometers that can operate at room temperature with high spatial resolution and magnetic-field sensitivity. In this work, we apply thin layers of Fe-triazole SCO complexes onto a single-crystal diamond with shallow NV centers and probe the fluctuating magnetic field. We combine a wide-field technique with temperature-dependent measurements of the NV centers’ longitudinal spin-relaxation time <i>T</i><sub>1</sub> and the decoherence time <i>T</i><sub>2</sub> to find that the complexes are paramagnetic in the investigated temperature range from 20 to 80 °C. We quantitatively describe the <i>T</i><sub>1</sub> time by a model considering the fluctuating magnetic field of the Fe<sup>II</sup> ions. While we see signatures of a local change in spin state in the <i>T</i><sub>1</sub> relaxometry data, apparent structural changes in the SCO material dominate the local magnetic environment of the NV centers. The results for the <i>T</i><sub>2</sub> time contrast the findings of the <i>T</i><sub>1</sub> times for the SCO complexes, which we attribute to different NV detection sensitivities toward Fe<sup>II</sup> and Fe<sup>III</sup> of the protocols. Our results on the magnetic properties of SCO materials highlight the capabilities of the NV center as a susceptible sensor for fluctuating magnetic fields. At the same time, spin switching of the complexes cannot be observed.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"15 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143713747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vertically Aligned Nanowires for Longitudinal Intracellular Sampling
IF 17.1 1区 材料科学
ACS Nano Pub Date : 2025-03-27 DOI: 10.1021/acsnano.4c18297
David Eun Reynolds, Yoon Ho Roh, Uday Chintapula, Emily Huynh, Phoebe Vallapureddy, Hong Huy Tran, Daeyeon Lee, Mark G. Allen, Xiaowei Xu, Jina Ko
{"title":"Vertically Aligned Nanowires for Longitudinal Intracellular Sampling","authors":"David Eun Reynolds, Yoon Ho Roh, Uday Chintapula, Emily Huynh, Phoebe Vallapureddy, Hong Huy Tran, Daeyeon Lee, Mark G. Allen, Xiaowei Xu, Jina Ko","doi":"10.1021/acsnano.4c18297","DOIUrl":"https://doi.org/10.1021/acsnano.4c18297","url":null,"abstract":"Cells are diverse systems with unique molecular profiles that support vital functions, such as energy production and nutrient absorption. Advances in omics have provided valuable insights into these cellular processes, but many of these tools rely on cell lysis, limiting the ability to track dynamic changes over time. To overcome this, methods for longitudinal profiling of living cells have emerged; however, challenges such as low throughput and genetic manipulation still need to be addressed. Nanomaterials, particularly nanowires, offer a promising solution due to their size, high aspect ratios, low cost, simplicity, and potential for high-throughput manufacturing. Here, we present a nanowire-based platform for longitudinal mRNA profiling in living cells using vertically aligned nickel nanowire arrays for efficient mRNA extraction with minimal cellular disruption. We demonstrate its ability to track enhanced green fluorescent protein expression and transcriptomic changes from drug responses in the same cells over time, showcasing the platform’s potential for dynamic cellular analysis.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"35 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143713752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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