ACS Nano最新文献

{"title":"Single Lithium-Ion Conductor Decorated LiMn2O4 with High Selectivity and Stability for Electrochemical Lithium Extraction","authors":"Ning Xue, Xiaoyan Wu, Hongsheng Shi, Yuyao Zhang, Yining Zhang, Yinjie Lv, Xinshui Zhang, Xin Chen, Yi Yu, Wei Liu","doi":"10.1021/acsnano.4c15473","DOIUrl":"https://doi.org/10.1021/acsnano.4c15473","url":null,"abstract":"Spinel LiMn₂O₄ (LMO) is commonly used for electrochemically extracting lithium ions from brine. However, its cycle stability is significantly reduced due to Mn²⁺ dissolution. Here, we report high-performance LMO particles decorated by Li_1.5Al_0.5Ge_1.5(PO₄)₃ (LAGP) as an electrode for electrochemical lithium extraction. Compared with bare sample, the modified electrode presents higher Li-ion selectivity because LAGP is a single Li-ion conductor, and as a result of avoiding the cointercalation of other ions in brine, the sample exhibits a higher Li-ion extraction capacity of 2.44 mmol·g^–1. The cycling stability is also improved in LMO with LAGP coating by alleviating the loss of manganese, indicating a reduced Mn loss of 0.20% after 100 cycles compared to the LAGP free counterpart of 0.47%. Our work demonstrates an effective method for lithium purification from brine, and the detailed mechanism is also studied systematically.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"4 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142718757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Holstein Polarons, Rashba-Like Spin Splitting, and Ising Superconductivity in Electron-Doped MoSe2","authors":"Sung Won Jung, Matthew D. Watson, Saumya Mukherjee, Daniil V. Evtushinsky, Cephise Cacho, Edoardo Martino, Helmuth Berger, Timur K. Kim","doi":"10.1021/acsnano.4c07805","DOIUrl":"https://doi.org/10.1021/acsnano.4c07805","url":null,"abstract":"Interaction between electrons and phonons in solids is a key effect defining the physical properties of materials, such as electrical and thermal conductivity. In transition metal dichalcogenides (TMDCs), the electron–phonon coupling results in the formation of polarons, quasiparticles that manifest themselves as discrete features in the electronic spectral function. In this study, we report the formation of polarons at the alkali-dosed MoSe₂ surface, where Rashba-like spin splitting of the conduction band states is caused by an inversion-symmetry breaking electric field. In addition, we observed a crossover from phonon-like to plasmon-like polaronic spectral features at the MoSe₂ surface with increasing doping. Our findings support the concept of electron–phonon coupling-mediated superconductivity in electron-doped layered TMDC materials, as observed using ionic liquid gating technology. Furthermore, the discovered spin-splitting at the Fermi level could offer crucial experimental validation for theoretical models of Ising-type superconductivity in these materials.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"25 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142718855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical Writing of Polar Skyrmionic Topological States via Extrinsic Dzyaloshinskii-Moriya-like Flexoelectricity in Ferroelectric Thin Films.","authors":"Kohta Kasai, Takashi Nojima, Yu Wang, Tao Xu, Hiroyuki Hirakata, Takahiro Shimada","doi":"10.1021/acsnano.4c06137","DOIUrl":"10.1021/acsnano.4c06137","url":null,"abstract":"<p><p>Exploring complex topological structures in condensed matter has shown promising applications in nanotechnology. Although polar topologies such as chiral vortices and skyrmions have been observed in ferroelectric heterostructures, their existence in simple systems has posed challenges due to the absence of intrinsic noncollinear interaction (like Dzyaloshinskii-Moriya interaction in ferromagnetics). Here, we demonstrate that a nanoindentation mechanically switches local polarizations to stable polar topologies, including skyrmions, within a room-temperature PbTiO₃ thin film via the flexoelectric effect as a noncollinear (Dzyaloshinskii-Moriya-like) driving force using phase-field simulations. In addition, by moving the indenter, the continuous polarization switching leads to the \"writing\" of arbitrary polar patterns (such as donut-like skyrmionium). Furthermore, the written topologies can be \"erased\" by applying a voltage with the same conducted indenter. Therefore, this study shows the writing and erasing process of room-temperature polar topologies in a ferroelectric thin film, which significantly advances their potential applications.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":" ","pages":"32451-32457"},"PeriodicalIF":15.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142612750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nano & AI: A Nobel Partnership","authors":"Xiaodong Chen, Jillian M. Buriak, Mathieu Salanne, Huolin Xin","doi":"10.1021/acsnano.4c14832","DOIUrl":"https://doi.org/10.1021/acsnano.4c14832","url":null,"abstract":"&lt;named-content content-type=\"pull-quote-attr-maintext\" specific-use=\"quote-only\" type=\"simple\"&gt;&lt;/named-content&gt;&lt;named-content content-type=\"pull-quote-attr-position\" specific-use=\"float\" type=\"simple\"&gt;&lt;/named-content&gt;The scientific community must remain vigilant, promoting AI that not only does things well but does good things. &lt;b&gt;&lt;i&gt;Quantum computing devices&lt;/i&gt;&lt;/b&gt;: Quantum computing holds the promise of exponentially increasing computing power by utilizing quantum bits (qubits) that exist in multiple states simultaneously. Nanotechnology is the enabler of creation of quantum materials and devices that enable stable and scalable qubits. (14−17) &lt;i&gt;ACS Nano&lt;/i&gt; is at the forefront of research into quantum materials that exhibit exotic quantum properties. These materials could revolutionize quantum computing by enabling more stable and scalable qubits, leading to powerful and reliable quantum computers for AI applications. Nanofabrication techniques enable precise control at the atomic level, essential for constructing qubits with high coherence times. Advances in two-dimensional materials and topological insulators are also paving the way for the quantum computing devices. &lt;b&gt;&lt;i&gt;Neuromorphic computing devices&lt;/i&gt;&lt;/b&gt;: Neuromorphic computing aims to mimic the neural architecture of the human brain to achieve efficient computations. Developing artificial neurons based on chemical or electric devices requires nanoscale fabrication to achieve high speeds and low power consumption. (18) Recent advances include memristive devices that emulate synaptic functions, enabling hardware implementations of neural networks. (19−21) &lt;b&gt;&lt;i&gt;3D architectures&lt;/i&gt;&lt;/b&gt;: Moving beyond the traditional 2D chip design, 3D architectures utilizing nanomaterials allow for higher transistor density and shorter interconnects, which in turn boosts computing performance and efficiency. (22,23) &lt;b&gt;&lt;i&gt;Nanosensors for data acquisition&lt;/i&gt;&lt;/b&gt;: AI thrives on data. Nanotechnology enables the development of highly sensitive and selective sensors that can gather vast amounts of data from the environment and importantly, directly from humans. This aspect comprises the research areas of wearable nanosensors, implantable nanosensors, nanosensors for brain–computer interfaces, and so on. (24) These sensor arrays generate rich data sets essential for training and improving AI algorithms, particularly in personalized medicine and human–machine interface. &lt;named-content content-type=\"pull-quote-attr-maintext\" specific-use=\"quote-only\" type=\"simple\"&gt;&lt;/named-content&gt;&lt;named-content content-type=\"pull-quote-attr-position\" specific-use=\"float\" type=\"simple\"&gt;&lt;/named-content&gt;Nano and AI are increasingly intertwined, forming a Nobel partnership that holds immense promise for the future. &lt;b&gt;&lt;i&gt;Nanomaterials discovery&lt;/i&gt;&lt;/b&gt;: Combining advances in AI with robotics can revolutionize the discovery of new nanomaterials through the rise of automated laboratories. This approach relies on the integration o","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"77 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142713224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Realization of Z₂ Topological Photonic Insulators Made from Multilayer Transition Metal Dichalcogenides.","authors":"Tommi Isoniemi, Paul Bouteyre, Xuerong Hu, Fedor Benimetskiy, Yue Wang, Maurice S Skolnick, Dmitry N Krizhanovskii, Alexander I Tartakovskii","doi":"10.1021/acsnano.4c09295","DOIUrl":"10.1021/acsnano.4c09295","url":null,"abstract":"<p><p>Monolayers of semiconducting transition metal dichalcogenides (TMDs) have long attracted interest for their intriguing optical and electronic properties. Recently, TMDs in their quasi-bulk form have started to show considerable promise for nanophotonics thanks to their high refractive indices, large optical anisotropy, wide transparency windows reaching to the visible, and robust room temperature excitons promising for nonlinear optics. Adherence of TMD layers to any substrate via van der Waals forces is a further key enabler for the nanofabrication of complex photonic structures requiring heterointegration. Here, we use the attractive properties of TMDs and realize topological spin-Hall photonic lattices made of arrays of triangular nanoholes in 50 to 100 nm thick WS₂ flakes exfoliated on SiO₂/Si substrates. High-quality structures are achieved by taking advantage of anisotropic dry etching dictated by the crystal axes of WS₂. Reflectance measurements at room temperature show a photonic gap opening in the near-infrared in trivial and topological phases. Unidirectional propagation along the domain interface is demonstrated in real space via circularly polarized laser excitation in samples with both zigzag and armchair domain boundaries. Finite-difference time-domain simulations are used to interpret optical spectroscopy results. Our work demonstrates the feasibility of more complex nanophotonic devices based on the layered (van der Waals) materials platform.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":" ","pages":"32547-32555"},"PeriodicalIF":15.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11603781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ionic Liquid Additive Mitigating Lithium Loss and Aluminum Corrosion for High-Voltage Anode-Free Lithium Metal Batteries.","authors":"Minghan Zhou, Weijian Liu, Qili Su, Junfeng Zeng, Xueao Jiang, Xuansheng Wu, Zhengjian Chen, Xiwen Wang, Zhe Li, Haijing Liu, Shiguo Zhang","doi":"10.1021/acsnano.4c13203","DOIUrl":"10.1021/acsnano.4c13203","url":null,"abstract":"<p><p>Concentrated electrolytes based on lithium bis(fluorosulfonyl)imide (LiFSI) have been proposed as an effective Li-compatible electrolyte for anode-free lithium metal batteries (AFLMBs). However, these electrolytes suffer from severe aluminum corrosion at an elevated potential. To address this issue, we propose a binary ionic liquid (IL) electrolyte additive comprising the 1-methyl-1-butyl pyrrolidinium cation (Pyr₁₄⁺), difluoro(oxalate)borate anion (DFOB^-), and difluorophosphate (PO₂F₂^-) anion to mitigate the Li inventory loss and Al corrosion in 4 M LiFSI/DME electrolyte simultaneously. On the anode side, the IL additive facilitates the formation of a robust Li₃N- and LiF-rich solid electrolyte interphase, promoting highly reversible Li plating/stripping and uniform Li deposition. Additionally, the ILs alter the Li⁺ solvation structure, leading to enhanced <i>t</i>_Li⁺ and rapid Li⁺ desolvation kinetics. Concurrently, on the cathode side, the ILs aid in the generation of dense LiF- and AlF-rich passivation films against Al corrosion. By using the IL-added electrolyte, the Cu||LiMn_0.7Fe_0.3PO₄ cell operates stably at 4.5 V, and the Cu||NCM613 cell with a high loading of 4.0 mA h cm^-2 sustains 142 cycles until 80% capacity retention. This research contributes to a deeper understanding of the IL additive mechanism at the electrode-electrolyte interfaces and offers a straightforward approach to designing practical high-voltage AFLMB electrolytes.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":" ","pages":"32959-32972"},"PeriodicalIF":15.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrafast Ion Transport in 2D Confined MXene for Improved Electrochemical Performance: Boron-Atom-Substituted -OH Termination.","authors":"Zhaoxi Liu, Yapeng Tian, Jian Yang, Song Xu, Qingyong Tian, Pengfei Yan, Buxing Han, Qun Xu","doi":"10.1021/acsnano.4c12874","DOIUrl":"10.1021/acsnano.4c12874","url":null,"abstract":"<p><p>Regulating the surface termination of a confined space to achieve ultrafast ion transport remains an ongoing challenge. Two-dimensional (2D) MXenes possess adjustable structures and interlayer spacing, which provide an ideal platform for in-depth investigation of ion transport in 2D confined space; however, the strong interaction of the negatively charged terminations in MXenes hinders the transport of intercalated cations. In this work, we proposed a strategy that precisely regulates the surface modification of Ti₃C₂T_<i>x</i> MXene with the weak polarity of boron atoms (SCB-MXene) via the distinct effect of supercritical CO₂. This not only could effectively substitute -OH termination in MXene but also can prevent the loss of -O active sites, and then, both ultrafast ion transport and high volumetric capacitance can be achieved simultaneously. Ideally, a volumetric capacitance up to 742.7 C cm^-3 at 1000 mV s^-1 for the SCB-MXene film as pseudocapacitive materials that provides an energy density of 66.3 Wh L^-1 even at an ultrahigh power density of 132.5 kW L^-1 is obtained, which is a prominent record of energy density and power density reported up to now. Subsequently, it can be used in large-scale energy storage and conversion devices.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":" ","pages":"32950-32958"},"PeriodicalIF":15.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unconventional Optical Matter of Hybrid Metal-Dielectric Nanoparticles at Interfaces.","authors":"Boris Louis, Chih-Hao Huang, Marc Melendez, Ana Sánchez-Iglesias, Jorge Olmos-Trigo, Sudipta Seth, Susana Rocha, Rafael Delgado-Buscalioni, Luis M Liz-Marzán, Manuel I Marqués, Hiroshi Masuhara, Johan Hofkens, Roger Bresolí-Obach","doi":"10.1021/acsnano.4c10418","DOIUrl":"10.1021/acsnano.4c10418","url":null,"abstract":"<p><p>Optical matter, a transient arrangement formed by the interaction of light with micro/nanoscale objects, provides responsive and highly tunable materials that allow for controlling and manipulating light and/or matter. A combined experimental and theoretical exploration of optical matter is essential to advance our understanding of the phenomenon and potentially design applications. Most studies have focused on nanoparticles composed of a single material (either metallic or dielectric), representing two extreme regimes, one where the gradient force (dielectric) and one where the scattering force (metallic) dominates. To understand their role, it is important to investigate hybrid materials with different metallic-to-dielectric ratios. Here, we combine numerical calculations and experiments on hybrid metal-dielectric core-shell particles (200 nm gold spheres coated with silica shells with thicknesses ranging from 0 to 100 nm). We reveal how silica shell thickness critically influences the essential properties of optical binding, such as interparticle distance, reducing it below the anticipated optical binding length. Notably, for silica shells thicker than 50 nm, we observed a transition from a linear arrangement perpendicular to polarization to a hexagonal arrangement accompanied by a circular motion. Further, the dynamic swarming assembly changes from the conventional dumbbell-shaped to lobe-like morphologies. These phenomena, confirmed by both experimental observations and dynamic numerical calculations, demonstrate the complex dynamics of optical matter and underscore the potential for tuning its properties for applications.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":" ","pages":"32746-32758"},"PeriodicalIF":15.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11614098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitophagy-Enhanced Nanoparticle-Engineered Mitochondria Restore Homeostasis of Mitochondrial Pool for Alleviating Pulmonary Fibrosis.","authors":"Yi Wang, Li-Fan Hu, Na-Hui Liu, Jing-Song Yang, Lei Xing, Jee-Heon Jeong, Ling Li, Hu-Lin Jiang","doi":"10.1021/acsnano.4c10328","DOIUrl":"10.1021/acsnano.4c10328","url":null,"abstract":"<p><p>Pulmonary fibrosis (PF) is an interstitial lung disease tightly associated with the disruption of mitochondrial pool homeostasis, a delicate balance influenced by functional and dysfunctional mitochondria within lung cells. Mitochondrial transfer is an emerging technology to increase functional mitochondria via exogenous mitochondrial delivery; however, the therapeutic effect on mitochondrial transfer is hampered during the PF process by the persistence of dysfunctional mitochondria, which is attributed to impaired mitophagy. Herein, we reported engineering <b>mito</b>chondria mediated by <b>m</b>itophagy-<b>e</b>nhanced <b>n</b>anoparticle (Mito-MEN), which promoted synchronal regulation of functional and dysfunctional mitochondria for treating PF. Mitophagy-enhanced nanoparticles (MENs) were fabricated through the encapsulation of Parkin <i>mRNA</i>, and the electrostatic interaction favored MENs to anchor isolated healthy mitochondria for the construction of Mito-MEN. Mito-MEN increased the load of functional exogenous mitochondria by enhancing mitochondrial delivery efficiency and promoted mitophagy of dysfunctional endogenous mitochondria. In a bleomycin (BLM)-induced PF mouse model, Mito-MEN repaired mitochondrial function and efficiently relieved PF-related phenotypes. This study provides a powerful tool for synchronal adjustment of mitochondrial pool homeostasis and offers a translational approach for pan-mitochondrial disease therapies.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":" ","pages":"32705-32722"},"PeriodicalIF":15.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Supramolecular Self-Assembled Nanoprodrug for Enhanced Ferroptosis Therapy.","authors":"Zhengwei Yu, Xin Xie, Qing Li, Yong Huang, Siqin Chen, Wentao Song, Jianwu Tian, Zhiyao Li, Chongzhi Wu, Bowen Li","doi":"10.1021/acsnano.4c09254","DOIUrl":"10.1021/acsnano.4c09254","url":null,"abstract":"<p><p>Ferroptosis can induce cell death that leverages Fe²⁺-triggered Fenton reactions within living organisms, leading to an excessive accumulation of lipid peroxides (LPOs) and inducing cell death. Ferroptosis can effectively circumvent the inevitable drug resistance encountered with traditional apoptotic therapies. However, several issues remain in the clinical application of ferroptosis anticancer therapy, primarily due to the poor efficiency of intracellular Fenton reaction. To address this issue, we developed a supramolecular self-assembled codelivery nanoprodrug (DOX@C18Fc-Q[7] NPs) composed of ferrocene (Fc)-based supramolecular amphiphiles (C18Fc-Q[7]) and a nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4) activator (doxorubicin, DOX). The C18Fc-Q[7] is based on Fc linked to a hydrophobic long-chain alkane via a disulfide linkage, which interacts with hydrophilic Q[7] to form self-assembled amphiphiles. Importantly, the host-guest interaction between Q[7] and Fc effectively enhances the solubility of Fc while maintaining the stability of the Fe²⁺ source. Moreover, C18Fc-Q[7] also acts as a good carrier for loading DOX due to its good self-assembly. In cancer cells, elevated glutathione (GSH) triggers the disassembly of nanoprodrug, leading to the release of DOX, which upregulates NOX4 expression and increases H₂O₂ level, thereby promoting an efficient Fenton reaction for Fc-induced ferroptosis. Moreover, DOX induces cell death through apoptosis, providing a synergistic effect to further enhance the ferroptosis therapy. <i>In vivo</i> studies have demonstrated that this enhanced ferroptosis therapy effectively inhibits tumor growth and metastasis while maintaining good biosafety.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":" ","pages":"32534-32546"},"PeriodicalIF":15.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142612746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}