ACS Nano最新文献

{"title":"Gender Disparities in Cardiovascular Literature","authors":"Ruirui Hou MD, Jian Ren MD","doi":"10.1016/j.jacc.2024.07.053","DOIUrl":"10.1016/j.jacc.2024.07.053","url":null,"abstract":"","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"84 20","pages":"Page e279"},"PeriodicalIF":21.7,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association and causal mediation between marital status and depression in seven countries","authors":"Xiaobing Zhai, Henry H. Y. Tong, Chi Kin Lam, Abao Xing, Yuyang Sha, Gang Luo, Weiyu Meng, Junfeng Li, Miao Zhou, Yangxi Huang, Ling Shing Wong, Cuicui Wang, Kefeng Li","doi":"10.1038/s41562-024-02033-0","DOIUrl":"https://doi.org/10.1038/s41562-024-02033-0","url":null,"abstract":"<p>Depression represents a significant global public health challenge, and marital status has been recognized as a potential risk factor. However, previous investigations of this association have primarily focused on Western samples with substantial heterogeneity. Our study aimed to examine the association between marital status and depressive symptoms across countries with diverse cultural backgrounds using a large-scale, two-stage, cross-country analysis. We used nationally representative, de-identified individual-level data from seven countries, including the USA, the UK, Mexico, Ireland, Korea, China and Indonesia (106,556 cross-sectional and 20,865 longitudinal participants), representing approximately 541 million adults. The follow-up duration ranged from 4 to 18 years. Our analysis revealed that unmarried individuals had a higher risk of depressive symptoms than their married counterparts across all countries (pooled odds ratio, 1.86; 95% confidence interval (CI), 1.61–2.14). However, the magnitude of this risk was influenced by country, sex and education level, with greater risk in Western versus Eastern countries (<i>β</i> = 0.36; 95% CI, 0.16–0.56; <i>P</i> &lt; 0.001), among males versus females (<i>β</i> = 0.25; 95% CI, 0.003–0.47; <i>P</i> = 0.047) and among those with higher versus lower educational attainment (<i>β</i>₂ = 0.34; 95% CI, 0.11–0.56; <i>P</i> = 0.003). Furthermore, alcohol drinking causally mediated increased later depressive symptom risk among widowed, divorced/separated and single Chinese, Korean and Mexican participants (all <i>P</i> &lt; 0.001). Similarly, smoking was as identified as a causal mediator among single individuals in China and Mexico, and the results remained unchanged in the bootstrap resampling validation and the sensitivity analyses. Our cross-country analysis suggests that unmarried individuals may be at greater risk of depression, and any efforts to mitigate this risk should consider the roles of cultural context, sex, educational attainment and substance use.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"1 1","pages":""},"PeriodicalIF":29.9,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Let Us Focus on Angina Mechanisms in Many, Not Just Typical Symptoms in a Few","authors":"Christiaan J.M. Vrints MD, PhD","doi":"10.1016/j.jacc.2024.05.085","DOIUrl":"10.1016/j.jacc.2024.05.085","url":null,"abstract":"","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"84 20","pages":"Page e275"},"PeriodicalIF":21.7,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Socioeconomic Status and Diagnostic Timeline on Clinical Outcomes in ATTR Cardiomyopathy","authors":"Kuan-Yu Chi MD ,&nbsp;Cesia Gallegos-Kattán MD, MHS ,&nbsp;Nikhil V. Sikand MD ,&nbsp;Marc D. Samsky MD ,&nbsp;Michael G. Nanna MD, MHS","doi":"10.1016/j.jacc.2024.07.050","DOIUrl":"10.1016/j.jacc.2024.07.050","url":null,"abstract":"","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"84 20","pages":"Pages e289-e290"},"PeriodicalIF":21.7,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of motor cortex in motor sequence execution depends on demands for flexibility","authors":"Kevin G. C. Mizes, Jack Lindsey, G. Sean Escola, Bence P. Ölveczky","doi":"10.1038/s41593-024-01792-3","DOIUrl":"https://doi.org/10.1038/s41593-024-01792-3","url":null,"abstract":"<p>The role of the motor cortex in executing motor sequences is widely debated, with studies supporting disparate views. Here we probe the degree to which the motor cortex’s engagement depends on task demands, specifically whether its role differs for highly practiced, or ‘automatic’, sequences versus flexible sequences informed by external cues. To test this, we trained rats to generate three-element motor sequences either by overtraining them on a single sequence or by having them follow instructive visual cues. Lesioning motor cortex showed that it is necessary for flexible cue-driven motor sequences but dispensable for single automatic behaviors trained in isolation. However, when an automatic motor sequence was practiced alongside the flexible task, it became motor cortex dependent, suggesting that an automatic motor sequence fails to consolidate subcortically when the same sequence is produced also in a flexible context. A simple neural network model recapitulated these results and offered a circuit-level explanation. Our results critically delineate the role of the motor cortex in motor sequence execution, describing the conditions under which it is engaged and the functions it fulfills, thus reconciling seemingly conflicting views about motor cortex’s role in motor sequence generation.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"33 1","pages":""},"PeriodicalIF":25.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alcohol’s necessary accessory","authors":"Shari Wiseman","doi":"10.1038/s41593-024-01802-4","DOIUrl":"10.1038/s41593-024-01802-4","url":null,"abstract":"","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"27 11","pages":"2053-2053"},"PeriodicalIF":21.2,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vive la Différence","authors":"Xuan Jiang MD, PhD,&nbsp;Tianxiang Gu MD, PhD","doi":"10.1016/j.jacc.2024.07.047","DOIUrl":"10.1016/j.jacc.2024.07.047","url":null,"abstract":"","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"84 20","pages":"Pages e293-e294"},"PeriodicalIF":21.7,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing Women's CABG Outcomes","authors":"Yuli Guo MD ,&nbsp;Ruirui Hou MD","doi":"10.1016/j.jacc.2024.07.052","DOIUrl":"10.1016/j.jacc.2024.07.052","url":null,"abstract":"","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"84 20","pages":"Page e295"},"PeriodicalIF":21.7,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The fly’s neural blueprint","authors":"Henrietta Howells","doi":"10.1038/s41593-024-01804-2","DOIUrl":"10.1038/s41593-024-01804-2","url":null,"abstract":"","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"27 11","pages":"2055-2055"},"PeriodicalIF":21.2,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Audio Summary","authors":"","doi":"10.1016/S0735-1097(24)09923-6","DOIUrl":"10.1016/S0735-1097(24)09923-6","url":null,"abstract":"","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"84 20","pages":"Page e267"},"PeriodicalIF":21.7,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}