ACS Nano最新文献_第6页

Enhanced Antiglioma Effect by a Vitamin D3-Inserted Lipid Hybrid Neutrophil Membrane Biomimetic Multimodal Nanoplatform

IF 17.1 1区材料科学

ACS Nano Pub Date : 2024-12-18 DOI: 10.1021/acsnano.4c13470

Weichong He, Wei Lv, Linfeng Liu, Yue Gong, Kefan Song, Jiangna Xu, Wei Zhao, Shengnan Li, Zhiyi Min, Qinhua Chen, Jiaqing Yin, Yuqin Chen, Hufeng Fang, Hongliang Xin, Xiangming Fang

{"title":"Enhanced Antiglioma Effect by a Vitamin D3-Inserted Lipid Hybrid Neutrophil Membrane Biomimetic Multimodal Nanoplatform","authors":"Weichong He, Wei Lv, Linfeng Liu, Yue Gong, Kefan Song, Jiangna Xu, Wei Zhao, Shengnan Li, Zhiyi Min, Qinhua Chen, Jiaqing Yin, Yuqin Chen, Hufeng Fang, Hongliang Xin, Xiangming Fang","doi":"10.1021/acsnano.4c13470","DOIUrl":"https://doi.org/10.1021/acsnano.4c13470","url":null,"abstract":"Glioblastoma, the most prevalent malignant brain tumor, is a lethal threat to human health, with aggressive and infiltrative growth characteristics that compromise the clinical treatment. Herein, we developed a vitamin D3-inserted lipid hybrid neutrophil membrane biomimetic multimodal nanoplatform (designated as NED@MnO2-DOX) through doxorubicin (DOX)-loaded manganese dioxide nanoparticles (MnO2) which were coated with a vitamin D3-inserted lipid hybrid neutrophil membrane. It was demonstrated that in addition to chemotherapy and chemo-dynamic therapy efficacy, NED@MnO2-DOX exhibited great power to activate and amplify immune responses related to the cGAS STING pathway, bolstering the secretion of type I interferon-β and proinflammatory cytokines, promoting the maturation of DC cells and infiltration of CD8+T cells into the glioma tissue, thereby reversing the immunosuppressive microenvironment of glioma from a “cold” tumor to a “hot” tumor. The biomimetic multimodal nanoplatform has potential as a multimodal strategy for glioma-targeted treatment, especially holding considerable promise for the development of innate immune therapy for glioma.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"86 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two Hundred Nanometer Thin Multifocal Graphene Oxide Metalens for Varying Magnification Broadband Imaging 用于不同放大率宽带成像的两百纳米薄型多焦氧化石墨烯金属膜

IF 17.1 1区材料科学

ACS Nano Pub Date : 2024-12-18 DOI: 10.1021/acsnano.4c13213

Guiyuan Cao, Siqi Wang, Wenbo Liu, Huihui Zhang, Jihong Han, Xining Xu, Jingheng Liu, Weisong Zhao, Haoyu Li, Han Lin, Baohua Jia, Shibiao Wei

引用次数: 0

Solvent-Driven Na Storage in SnS2 Anodes: Atomistic Simulation-Guided Strategies for Reversible Reactions, Solid Electrolyte Interphase, and Morphological Transformation SnS2 阳极中溶剂驱动的 Na 储存：原子模拟引导的可逆反应、固体电解质相间和形态转变策略

IF 17.1 1区材料科学

ACS Nano Pub Date : 2024-12-18 DOI: 10.1021/acsnano.4c13669

Young-Hoon Kim, Joo-Yeon Moon, Yeong-In Yoon, Jae-Chul Lee, Yong-Seok Choi

{"title":"Solvent-Driven Na Storage in SnS2 Anodes: Atomistic Simulation-Guided Strategies for Reversible Reactions, Solid Electrolyte Interphase, and Morphological Transformation","authors":"Young-Hoon Kim, Joo-Yeon Moon, Yeong-In Yoon, Jae-Chul Lee, Yong-Seok Choi","doi":"10.1021/acsnano.4c13669","DOIUrl":"https://doi.org/10.1021/acsnano.4c13669","url":null,"abstract":"Crystalline SnS2 accommodates Na ions through intercalation–conversion–alloying (ICA) reactions, exhibiting a natural potential for high energy storage, while its layered structure facilitates rapid charging. However, these intrinsic advantages are not fully realized in practical battery applications. Herein, utilizing an innovative integration of machine-learning-based thermodynamics, artificial-neural-network-assisted molecular dynamics, and density functional theory, specific solvents are demonstrated to effectively tailor the reaction pathways. This strategy not only steers phase transition pathways but also significantly reduces the formation of the solid electrolyte interphase (SEI), which is a common issue in recent battery research. These characteristics of solvents enable reversible ICA reactions and also aid the transformation of microsized SnS2 particles into 3D porous nanostructures with minimal SEI formation. The performance of our Na–SnS2 half-cells achieve 1100 mAh g–1 (97% of the theoretical capacity) at 0.5 C, placing them among the top performers for Na storage. By moving beyond the traditional view of electrolyte solvents as a simple medium for ion transport, this work highlights the critical impact of solvent selection on enabling reversible reactions and morphological transformation of SnS2 anodes with minimal SEI formation and setting benchmarks for anode performance in energy storage systems based on ICA reactions.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"30 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142841745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single-Walled Carbon Nanotubes as Optical Transducers for Nanobiosensors In Vivo

IF 17.1 1区材料科学

ACS Nano Pub Date : 2024-12-18 DOI: 10.1021/acsnano.4c13076

Zachary Cohen, Ryan M. Williams

{"title":"Single-Walled Carbon Nanotubes as Optical Transducers for Nanobiosensors In Vivo","authors":"Zachary Cohen, Ryan M. Williams","doi":"10.1021/acsnano.4c13076","DOIUrl":"https://doi.org/10.1021/acsnano.4c13076","url":null,"abstract":"Semiconducting single-walled carbon nanotubes (SWCNTs) may serve as signal transducers for nanobiosensors. Recent studies have developed innovative methods of engineering molecularly specific sensors, while others have devised methods of deploying such sensors within live animals and plants. These advances may potentiate the use of implantable, noninvasive biosensors for continuous drug, disease, and contaminant monitoring based on the optical properties of single-walled carbon nanotubes (SWCNTs). Such tools have substantial potential to improve disease diagnostics, prognosis, drug safety, therapeutic response, and patient compliance. Outside of clinical applications, such sensors also have substantial potential in environmental monitoring or as research tools in the lab. However, substantial work remains to be done to realize these goals through further advances in materials science and engineering. Here, we review the current landscape of quantitative SWCNT-based optical biosensors that have been deployed in living plants and animals. Specifically, we focused this review on methods that have been developed to deploy SWCNT-based sensors in vivo as well as analytes that have been detected by SWCNTs in vivo. Finally, we evaluated potential future directions to take advantage of the promise outlined here toward field-deployable or implantable use in patients.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"23 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why Mixed Halides in 2D Chiral Perovskites Weaken Chirality-Induced Spin Selectivity

IF 17.1 1区材料科学

ACS Nano Pub Date : 2024-12-18 DOI: 10.1021/acsnano.4c14328

Soirik Dan, Subham Paramanik, Amlan J. Pal

{"title":"Why Mixed Halides in 2D Chiral Perovskites Weaken Chirality-Induced Spin Selectivity","authors":"Soirik Dan, Subham Paramanik, Amlan J. Pal","doi":"10.1021/acsnano.4c14328","DOIUrl":"https://doi.org/10.1021/acsnano.4c14328","url":null,"abstract":"2D Ruddlesden–Popper (RP) perovskites, upon inclusion of a chiral amine, exhibit chirality-induced spin selectivity (CISS). Although alloying at the halogen site in MBA-based RPs (MBA: methylbenzylammonium) is one of the suitable routes to tune the CISS effect, the mixed-halide RP perovskites exhibited complete suppression of chirality when probed through circular dichroism (CD). Here, we present the CISS effect in a series of mixed-halide RP perovskites. We show that photoinduced halide segregation is the origin for the apparent chirality suppression. The spin-dependent charge transport was evidenced through magnetic-conducting atomic force microscopy (mc-AFM) studies and magnetoresistance (MR) measurements. The mc-AFM results show that in (R/S-MBA)2PbI4(1–x)Br4x, the CISS effect decreases with bromide inclusion, nonmonotonically; the microstrain developed in the lattice and the spin-polarized charge transport are found to be correlated. Such a behavior has been explained through an inhomogeneity in the strength of the hydrogen bond between the organic moieties and halogens in the inorganic framework of the compounds. Our results further inferred that the hydrogen-bond-induced coupling transfers the chirality from the amine to the inorganic sublattice. The work explains the weakened CISS effect in mixed-halide chiral RP perovskites and provides a strategy to tune the spin-polarized charge transport as well.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"10 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid Deployment of Antiviral Drugs Using Single-Virus Tracking and Machine Learning

IF 17.1 1区材料科学

ACS Nano Pub Date : 2024-12-18 DOI: 10.1021/acsnano.4c10136

Meng-Die Zhu, Xue-Hui Shi, Hui-Ping Wen, Li-Ming Chen, Dan-Dan Fu, Lei Du, Jing Li, Qian-Qian Wan, Zhi-Gang Wang, Chuanming Yu, Dai-Wen Pang, Shu-Lin Liu

引用次数: 0

Equal-Bilayer MoSe2 Grown by a Nucleation-Etching Strategy with High Carrier Mobility

IF 17.1 1区材料科学

ACS Nano Pub Date : 2024-12-18 DOI: 10.1021/acsnano.4c10120

Jiamei Chen, Maolin Chen, Xing Xin, Wei Xin, Weizhen Liu, Youzhe Bao, Mengfan Ding, Peng Li, Jiangang Ma, Haiyang Xu, Yichun Liu

{"title":"Equal-Bilayer MoSe2 Grown by a Nucleation-Etching Strategy with High Carrier Mobility","authors":"Jiamei Chen, Maolin Chen, Xing Xin, Wei Xin, Weizhen Liu, Youzhe Bao, Mengfan Ding, Peng Li, Jiangang Ma, Haiyang Xu, Yichun Liu","doi":"10.1021/acsnano.4c10120","DOIUrl":"https://doi.org/10.1021/acsnano.4c10120","url":null,"abstract":"Bilayer transition metal chalcogenides (TMDs) have gradually attracted a great deal of attention due to the higher density of states and carrier mobility than monolayer TMDs. Controlling the uniformity of the layer number is very crucial because it will intensively influence the physical properties. However, it is difficult to synthesize equal-bilayer (EB) TMDs with two identical layers via a normal layer-by-layer strategy. Most reported bilayer TMDs are not uniform and such unequal bilayers would introduce a sizable Schottky barrier, resulting in the low carrier mobility. Here, a nucleation-etching strategy is proposed to grow EB-MoSe2 by chemical vapor deposition (CVD), which breaks the limitations of normal layer-by-layer strategy. The second layer is preferentially formed beneath the first layer rather than above, and a different etching phenomenon is also observed, which occurs more preferentially at the overlapping grain boundary sites on the top layer. The obtained EB-MoSe2 flakes are 3R-stack with high crystal quality. Furthermore, the contact between EB-MoSe2 and metal electrodes is greatly improved, thereby EB-MoSe2 transistors exhibit an order of magnitude higher carrier mobility (104 cm2 V–1 s–1) than that of UEB-MoSe2 transistors (12 cm2 V–1 s–1). This value is also at a relatively high level compared with reported results. Our work offers a feasible strategy for the synthesis of EB-TMDs with high carrier mobility, which is meaningful for developing high-performance 2D optoelectronic devices.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"40 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantum-State Renormalization in Semiconductor Nanoparticles

IF 17.1 1区材料科学

ACS Nano Pub Date : 2024-12-18 DOI: 10.1021/acsnano.4c09833

Jie Chen, Rena C. Kramer, Thomas R. Howell, Richard A. Loomis

引用次数: 0

Halide Perovskite Photodiode Integrated CMOS Imager

IF 17.1 1区材料科学

ACS Nano Pub Date : 2024-12-18 DOI: 10.1021/acsnano.4c13136

Wenya Song, Jubin Kang, Karim Elkhouly, Sarah Hamdad, Xin Zhang, Maria Isabel Pintor Monroy, Abu Bakar Siddik, Patrick Carolan, Sownder Subramaniam, Yinghuan Kuang, Florian De Roose, Erwin Vandenplas, Naresh Chandrasekaran, Joo Hyoung Kim, Robert Gehlhaar, Seong-Jin Kim, Jiwon Lee, Jan Genoe

{"title":"Halide Perovskite Photodiode Integrated CMOS Imager","authors":"Wenya Song, Jubin Kang, Karim Elkhouly, Sarah Hamdad, Xin Zhang, Maria Isabel Pintor Monroy, Abu Bakar Siddik, Patrick Carolan, Sownder Subramaniam, Yinghuan Kuang, Florian De Roose, Erwin Vandenplas, Naresh Chandrasekaran, Joo Hyoung Kim, Robert Gehlhaar, Seong-Jin Kim, Jiwon Lee, Jan Genoe","doi":"10.1021/acsnano.4c13136","DOIUrl":"https://doi.org/10.1021/acsnano.4c13136","url":null,"abstract":"Thin film photodiodes (TFPD) can supplement complementary metal-oxide-semiconductor (CMOS) image sensor vision by their exotic optoelectronic properties assisted by their monolithic processability. Halide perovskites are known to show outstanding optoelectronic properties, such as large absorption coefficient, long carrier diffusion lengths, and high carrier mobility, leading to high external quantum efficiency (EQE) and fast charge transport in photodiodes (PDs), especially compared with other thin-film photodiode candidates. In this paper, high-resolution two-dimensional (2D) and three-dimensional (3D) imaging capabilities are demonstrated using perovskite photodetection material with a silicon (Si) read-out integrated circuit (ROIC). The integration of this perovskite photodiode (PePD) on the Si ROIC provides fine resolution for 2D imaging. The fast carrier transport properties of the PePD enable depth sensing of objects using the same sensor. 3D imaging is demonstrated using the proposed top-electrode controlled indirect time-of-flight (iToF) operation supported by the fast PD switching through the top common electrode of the TFPD image sensor pixel. It is expected that the PePDs on Si ROIC could mark a significant milestone for the TFPD imaging platform with their outstanding optoelectronic performance in combination with the CMOS image sensor technology, not only for conventional 2D imaging but also by enabling extensions toward 3D sensing, promising applications in automotive, augmented reality (AR), and virtual reality (VR).","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"114 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Boosting Formate Production in Electrocatalytic CO2 Reduction on Bimetallic Catalysts Enriched with In–Zn Interfaces

IF 17.1 1区材料科学

ACS Nano Pub Date : 2024-12-18 DOI: 10.1021/acsnano.4c15927

Rui Zhao, Huihua Luo, Ting Ouyang, Zhao-Qing Liu

{"title":"Boosting Formate Production in Electrocatalytic CO2 Reduction on Bimetallic Catalysts Enriched with In–Zn Interfaces","authors":"Rui Zhao, Huihua Luo, Ting Ouyang, Zhao-Qing Liu","doi":"10.1021/acsnano.4c15927","DOIUrl":"https://doi.org/10.1021/acsnano.4c15927","url":null,"abstract":"We present an effective strategy for developing the dispersing strong-binding metal In on the surface of weak-binding metal Zn, which modulates the binding energy of the reaction intermediates and further facilitates the efficient conversion of CO2 to formate. The In–Zn interface (In–Zn2) benefits from the formation of active sites through favorable orbital interactions, leading to a Faradaic efficiency of 82.7% and a formate partial current density of 12.39 mA cm–2, along with stable performance for over 15 h at −1.0 V versus the reversible hydrogen electrode. Both in situ Fourier transform infrared spectroscopy and density functional theory calculations show that the In–Zn bimetallic catalyst can deliver superior binding energy to the *OCHO intermediate, thereby fundamentally accelerating the conversion of CO2 to formate. In addition, the exposed bimetallic interface promotes efficient capture and activation of CO2 molecules and the dynamics within the In–Zn catalyst significantly reduce the energy barrier associated with the generation of HCOO–, thus augmenting the selectivity and catalytic activity for formate generation.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"10 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0