{"title":"Skin and Bone: Chronic Paronychia Leading to Osteomyelitis.","authors":"Jonathan de Vries, Mimi Chung, Boni E Elewski","doi":"10.1159/000542607","DOIUrl":"10.1159/000542607","url":null,"abstract":"<p><strong>Introduction: </strong>Paronychia can be both acute and chronic dependent on the chronicity of disease, with different etiologies linked to each. Acute paronychia is commonly secondary to bacterial infections, while chronic paronychia can be multifactorial and include inflammatory causes.</p><p><strong>Case presentation: </strong>We present a case of chronic paronychia that developed into osteomyelitis of the affected finger.</p><p><strong>Conclusion: </strong>Because nail folds are anatomically close to the phalanges, it is important to monitor for worsening disease, as paronychia can develop into more serious infections.</p>","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":"11 3","pages":"287-290"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Asz-Sigall, Alejandra Segarra-Ponce, Sofía Olvera-Lerma, Luis Enrique Cano-Aguilar, Eduardo Corona-Rodarte
{"title":"Red Scalp Disease: An Underdiagnosed Entity.","authors":"Daniel Asz-Sigall, Alejandra Segarra-Ponce, Sofía Olvera-Lerma, Luis Enrique Cano-Aguilar, Eduardo Corona-Rodarte","doi":"10.1159/000542573","DOIUrl":"10.1159/000542573","url":null,"abstract":"<p><strong>Introduction: </strong>Red scalp disease or scalp rosacea, an inflammatory dermatosis, is frequently misdiagnosed as scarring alopecia due to nonspecific trichoscopic findings and limited case reports. While facial rosacea is well-documented, rosacea affecting extrafacial sites, such as the scalp, remains underrecognized. Accurate diagnosis is crucial to avoid unnecessary treatments and to establish an appropriate prognosis.</p><p><strong>Case report: </strong>A 70-year-old male with an asymptomatic red scalp for 1 year, unresponsive to topical treatments, presented to our clinic. Examination revealed diffuse erythema with papules and pustules. Trichoscopy showed vascular polygons, \"caterpillar hair\" vessels, linear arterial branching, and hairpin vessels. Diagnosis of scalp rosacea was made, and significant improvement was observed after 2 months of oral tetracycline therapy.</p><p><strong>Discussion/conclusion: </strong>Red scalp disease is characterized by diffuse erythema, inflammatory lesions, and vascular changes. Patients often exhibit mild facial photosensitivity but may not show prominent facial rosacea symptoms. Distinct trichoscopic patterns can assist in accurate diagnosis. Early recognition and treatment with systemic antibiotics, such as tetracyclines, are crucial to prevent progression to more severe inflammation. Increased awareness among dermatologists and trichologists is essential to enhance the diagnosis and management of this condition.</p>","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":"11 3","pages":"291-295"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The 100 Most-Cited Publications in Lichen Planopilaris: A Bibliometric Analysis.","authors":"Tanya Boghosian, Narges Maskan Bermudez, Antonella Tosti","doi":"10.1159/000542898","DOIUrl":"10.1159/000542898","url":null,"abstract":"<p><strong>Introduction: </strong>Lichen planopilaris (LPP) is a rare scarring alopecia with poorly understood etiology, leading to challenges in both diagnosis and management. With an increasing number of studies focused on its clinical presentation, histopathology, and trichoscopic features, a comprehensive bibliometric analysis of high-impact LPP research is necessary to assess current trends and identify gaps in the literature.</p><p><strong>Methods: </strong>The objective of this study was to analyze trends in LPP research using the top 100 most-cited articles from Web of Science.</p><p><strong>Results: </strong>The average number of citations per article was 80.4 (range: 37-289), with publication dates ranging from 1990 to 2021. The most-cited article was Kossard's \"Progressive Frontal Scarring Alopecia in Postmenopausal Women\" with 289 citations. The USA (<i>n</i> = 47) had the most publications, followed by England (<i>n</i> = 18) and Spain (<i>n</i> = 14). Most articles were LOE 3 (<i>n</i> = 34) focusing on the \"clinical and histopathological presentation\" (<i>n</i> = 33). Key reported trichoscopic features included perifollicular erythema, perifollicular scaling, and loss of follicular ostia.</p><p><strong>Conclusion: </strong>This bibliometric analysis highlights foundational LPP studies, emphasizing key trichoscopic features while revealing gaps in high-level evidence. It underscores the need for more rigorous research and expanded geographic diversity to enhance diagnostic markers, refine trichoscopic criteria, and improve therapeutic approaches.</p>","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":"11 3","pages":"245-254"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Illness Perceptions, Knowledge, and Quality of Life in Lichen Planopilaris Patients.","authors":"Azin Tahvildari, Sarina Borran, Zahra Razzaghi, Sahar Dadkhahfar","doi":"10.1159/000543451","DOIUrl":"10.1159/000543451","url":null,"abstract":"<p><strong>Introduction: </strong>Lichen planopilaris (LPP) is an inflammatory disease, leading to permanent hair loss, which significantly affects the psychosocial and self-image of patients with this condition; however, the impact of this condition on patients' quality of life (QoL), their perception of disease, and their knowledge about it have rarely been studied. This study aimed to investigate patients' knowledge and perspective on their disease and its association with their QoL and the extent of skin involvement.</p><p><strong>Methods: </strong>Patients diagnosed with LPP and confirmed through a biopsy from 2022 to 2023 completed a questionnaire covering demographic characteristics, the Illness Perception Questionnaire, disease and therapy knowledge, and the Dermatology Life Quality Index. Additionally, a dermatologist (S.D.) examined the Lichen Planopilaris Activity Index (LPPAI).</p><p><strong>Results: </strong>This study enrolled 42 LPP patients, with 81% being female and 73.8% under 60 years old. The LPPAI did not correlate with knowledge (<i>r</i> = 0.04, <i>p</i> = 0.783), illness perception (<i>r</i> = 0.097, <i>p</i> = 0.543), or QoL scores (<i>r</i> = 0.119, <i>p</i> = 0.452). However, QoL was positively linked to knowledge (<i>r</i> = 0.382, <i>p</i> = 0.013) and illness perception scores (<i>r</i> = 0.398, <i>p</i> = 0.009). Patients with a longer disease duration had higher knowledge scores (<i>r</i> = 0.400, <i>p</i> = 0.009).</p><p><strong>Conclusion: </strong>Dermatologists should note that enhancing patients' knowledge of their disease and assessing their illness perceptions can help identify and correct misconceptions, improving treatment outcomes and their QoL.</p>","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":"11 3","pages":"221-226"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mona Elradi, Dina E Hamed, Maha S Eltwansy, Doaa Hosny
{"title":"The Impact of Acne on Quality of Life: A Cross-Sectional Study from Egypt.","authors":"Mona Elradi, Dina E Hamed, Maha S Eltwansy, Doaa Hosny","doi":"10.1159/000543051","DOIUrl":"10.1159/000543051","url":null,"abstract":"<p><strong>Introduction: </strong>Nowadays, the impact of acne on the psyche of patients is evident to physicians and patients themselves. Studies concerned with the relation between acne and quality of life (QOL) are scarce in the Middle East.</p><p><strong>Methods: </strong>This prospective cross-sectional study included 247 patients. The severity of acne was evaluated using the Global Acne Grading System (GAGS). Then, patients were asked to fill in the Arabic versions of the Dermatology Life Quality Index (DLQI) and the Cardiff Acne Disability Index (CADI).</p><p><strong>Results: </strong>The mean CADI and DLQI scores were 6 ± 3.2 and 9.8 ± 5.5, respectively. There was a weakly significant positive correlation between CADI and GAGS, gender, cheek, chin, chest, and upper back localization of lesions (<i>p</i> ≤ 0.05). Moreover, there was a weakly significant positive correlation between only GAGS and DLQI (<i>r</i> = 0.125, <i>p</i> = 0.000).</p><p><strong>Conclusion: </strong>Acne has an evident negative impact on the QOL of the participants. Assessing the QOL of acne patients and psychiatric consultation are advised to be standard measures of any management approach for acne patients for their well-being.</p>","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":"11 3","pages":"255-261"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ursula Biba, Samantha Gregoire, Katherine Sanchez, Natasha Atanaskova Mesinkovska, Monique Margaret Waldman, Lisa Anderson, Arash Mostaghimi
{"title":"The Relationship between Stigma and Healthcare Interaction in Alopecia Areata.","authors":"Ursula Biba, Samantha Gregoire, Katherine Sanchez, Natasha Atanaskova Mesinkovska, Monique Margaret Waldman, Lisa Anderson, Arash Mostaghimi","doi":"10.1159/000546216","DOIUrl":"10.1159/000546216","url":null,"abstract":"<p><strong>Introduction: </strong>People with alopecia areata (AA) experience stigma, but little is known about how this affects healthcare interaction (HCI). We aim to explore the relationship between stigma and HCI in AA.</p><p><strong>Methods: </strong>A cross-sectional survey of 500 members of the National Alopecia Areata Foundation was performed. Survey items related to stigma and HCI were summed and sorted into low, medium, and high tertiles. Multinomial logistic regressions were performed to control for demographic and clinical factors.</p><p><strong>Results: </strong>Respondents (<i>n</i> = 500) were white (80.0%), female (86.2%), and insured (96.0%), with a plurality earning over USD 100,000 annually (34.2%). Participants in the high-stigma subgroup were more likely to be in the low-HCI subgroup (relative risk ratio [RRR]: 2.22; 95% CI: 1.31-3.76; <i>p</i> = 0.003), in comparison to participants in the low- or moderate-stigma subgroups (RRR for both: 0.45; <i>p</i> < 0.05). This relationship was independent of demographics and clinical characteristics. However, data are from a population with limited socioeconomic diversity and high baseline healthcare engagement.</p><p><strong>Conclusion: </strong>People with AA who experience high stigma are less likely to interact with the healthcare system, which cannot be explained by demographics or clinical factors. Stigma and HCI may be related in a dose-dependent manner, and future investigation is needed to support access to care.</p>","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":" ","pages":"1-7"},"PeriodicalIF":1.4,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aditya Joshi, David J Griego, Lauren Gawey, Raveena Ghanshani, Khiem A Tran, Jennifer L Hsiao, Vivian Y Shi
{"title":"Bibliometric Analysis in Hyperhidrosis: Recent Publication Trends from 2015 to 2025.","authors":"Aditya Joshi, David J Griego, Lauren Gawey, Raveena Ghanshani, Khiem A Tran, Jennifer L Hsiao, Vivian Y Shi","doi":"10.1159/000545767","DOIUrl":"10.1159/000545767","url":null,"abstract":"<p><strong>Introduction: </strong>Hyperhidrosis is a chronic dermatologic condition that significantly impacts quality of life. While research has expanded in recent years, bibliometric analyses exploring publication trends remain limited. This study examined the 100 most-cited articles from 2015 to 2025 to assess research priorities.</p><p><strong>Methods: </strong>A Scopus search was conducted on January 2, 2025, using the terms \"hyperhidrosis\", \"primary hyperhidrosis\", \"secondary hyperhidrosis\", and \"excessive sweating\". Non-English, abstract-only, and non-hyperhidrosis focused articles were excluded. Two reviewers screened and identified the 100 most-cited publications. Data were analyzed for publication year, authorship, country, study design, journal, and topic focus. The Oxford Centre for Evidence-Based Medicine Level of Evidence (LoE) framework was used to assess study quality.</p><p><strong>Results: </strong>The majority (76%) of highly cited articles were published between 2015 and 2019. Randomized controlled trials (20%), cohort studies (18%), and case-control studies (16%) were the most common study types. Using LoE assessment, 33% of studies were level 1 (high-quality evidence). Research on treatments (55%) dominated, followed by quality of life (12%) and outcome measures (11%). The USA led in publication output.</p><p><strong>Conclusion: </strong>This bibliometric analysis identifies evolving research priorities toward minimally invasive treatments and patient-centered outcomes, providing direction for future research and improvements in clinical practice.</p>","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":" ","pages":"1-16"},"PeriodicalIF":1.4,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12158438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rayad B Shams, Victoria C Lam, William W Moorer, Philip M McDaniel, Christopher J Sayed
{"title":"Predictive Factors for Nonattendance in Hidradenitis Suppurativa Patients: A Case-Control Study.","authors":"Rayad B Shams, Victoria C Lam, William W Moorer, Philip M McDaniel, Christopher J Sayed","doi":"10.1159/000546044","DOIUrl":"10.1159/000546044","url":null,"abstract":"<p><strong>Introduction: </strong>Nonattendance to dermatology appointments can disrupt continuity of care and may lead to worse outcomes among patients. Factors related to nonattendance among Hidradenitis suppurativa (HS) patients have not been adequately explored.</p><p><strong>Methods: </strong>This case-control study at an HS subspecialty clinic in the southeastern USA explores patient characteristics and encounter variables predictive of nonattendance using demographic, employment, health insurance, and distance to clinic data using both univariable and mixed-model multivariable logistical regression.</p><p><strong>Results: </strong>Return visits, Black and unknown race, disabled and unemployed status, Medicaid insurance, current smoking or former smoking status, and living 1-2 h, or 2-3 h away from clinic were found to be significant predictors of nonattendance on the multivariable regression model.</p><p><strong>Conclusions: </strong>These findings highlight the role social determinants of health play in dermatological care access and the need for increasing accessibility to continued care among certain HS patient populations.</p>","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":" ","pages":"1-5"},"PeriodicalIF":1.4,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John Verrinder Veasey, Cristine Zampieri Braga, Gustavo de Sá Menezes Carvalho, Guilherme Camargo Julio Valinoto
{"title":"Are Antifungal Nail Polish Bottles a Reservoir for Contamination in Patients Treating Onychomycosis?","authors":"John Verrinder Veasey, Cristine Zampieri Braga, Gustavo de Sá Menezes Carvalho, Guilherme Camargo Julio Valinoto","doi":"10.1159/000546045","DOIUrl":"10.1159/000546045","url":null,"abstract":"<p><strong>Introduction: </strong>Onychomycosis presents significant therapeutic challenges, with high recurrence rates and the need for prolonged treatment adherence. While previous studies have explored the contamination risks of cosmetic nail polishes, little is known about the microbiological safety of antifungal nail polishes used in onychomycosis treatment.</p><p><strong>Methods: </strong>This study investigated potential contamination in antifungal nail polish bottles containing ciclopirox olamine 8% (CO) and amorolfine 5% (AM) used by patients diagnosed with onychomycosis confirmed by mycological exams. After treatment, applicators were analyzed using Sabouraud and Mycosel<sup>®</sup> culture media.</p><p><strong>Results: </strong>Of the 67 randomly selected nails treated, 100% showed positive direct mycological examination, and 49% had fungal growth in culture. However, none of the 67 applicators (49 CO and 18 AM) exhibited fungal growth.</p><p><strong>Conclusion: </strong>The study findings suggest that antifungal nail polishes do not act as contamination reservoirs, likely due to their inherent antifungal properties. Nonetheless, patients should be educated on proper hygiene to minimize cross-contamination risks.</p>","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":" ","pages":"1-5"},"PeriodicalIF":1.4,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12158436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katherine Sanchez, Ursula Biba, Samantha Gregoire, Natasha Atanaskova Mesinkovska, Monique Margaret Waldman, Lisa Anderson, Arash Mostaghimi
{"title":"Components of Severity in Alopecia Areata.","authors":"Katherine Sanchez, Ursula Biba, Samantha Gregoire, Natasha Atanaskova Mesinkovska, Monique Margaret Waldman, Lisa Anderson, Arash Mostaghimi","doi":"10.1159/000545861","DOIUrl":"10.1159/000545861","url":null,"abstract":"<p><strong>Introduction: </strong>Severity of alopecia areata (AA) has been commonly defined by clinician assessment of scalp hair loss. Our aim was to characterize patient-reported factors beyond scalp hair loss that contribute to AA severity while modifying for socioeconomic factors.</p><p><strong>Methods: </strong>Patients with AA were recruited to take a survey. Multivariable linear regression was performed to evaluate lifetime AA severity while adjusting for socioeconomic variables, current AA severity at the time of survey, and patient-reported disease burden.</p><p><strong>Results: </strong>Patient-reported AA severity was associated with scalp hair loss (OR: 4.19, 95% CI: [1.35-13], <i>p</i> = 0.013), facial hair loss (OR: 3.55, 95% CI: [1.75-7.21], <i>p</i> < 0.001), increased financial burden (OR: 2.41, 95% CI: [1.21-4.8], <i>p</i> = 0.013), and greater emotional burden (OR: 2.96, 95% CI: [1.48-5.93], <i>p</i> = 0.002), while presence of comorbidities were linked to less severe AA (OR: 0.38, 95% CI: [0.17-0.84], <i>p</i> = 0.017).</p><p><strong>Conclusion: </strong>Survey population was homogeneous and may not reflect the general community with AA. Self-reported data may introduce recency or recall bias. Scalp and facial hair loss, along with emotional and financial burdens, correlate with increased patient-reported AA severity. This suggests factors beyond scalp hair loss should be considered when assessing AA severity.</p>","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":" ","pages":"1-6"},"PeriodicalIF":1.4,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}