Skin Appendage Disorders最新文献

Trichoscopy of Discoid Lupus Erythematosus in Caucasian Scalp: A Review. 白种人头皮盘状红斑狼疮的三镜检查：综述。

IF 1.4

Skin Appendage Disorders Pub Date : 2024-10-01 Epub Date: 2024-05-31 DOI: 10.1159/000539189

Elisa Milan, Roberta Vezzoni, Michela V R Starace

引用次数: 0

The Comparative Effects of Monotherapy with Topical Minoxidil, Oral Finasteride, and Topical Finasteride in Postmenopausal Women with Pattern Hair Loss: A Retrospective Cohort Study. 外用米诺地尔、口服非那雄胺和外用非那雄胺单一疗法对绝经后模式性脱发妇女的比较效果：一项回顾性队列研究。

IF 1.4

Skin Appendage Disorders Pub Date : 2024-08-01 Epub Date: 2024-04-29 DOI: 10.1159/000538621

Michela Valeria Rita Starace, Aditya K Gupta, Mary A Bamimore, Mesbah Talukder, Federico Quadrelli, Bianca Maria Piraccini

{"title":"The Comparative Effects of Monotherapy with Topical Minoxidil, Oral Finasteride, and Topical Finasteride in Postmenopausal Women with Pattern Hair Loss: A Retrospective Cohort Study.","authors":"Michela Valeria Rita Starace, Aditya K Gupta, Mary A Bamimore, Mesbah Talukder, Federico Quadrelli, Bianca Maria Piraccini","doi":"10.1159/000538621","DOIUrl":"10.1159/000538621","url":null,"abstract":"Introduction: Oral finasteride and topical minoxidil are long-standing androgenetic alopecia (AGA) treatments; topical finasteride is a more recent medicine. Few studies have compared their therapeutic effects in postmenopausal women. We compared the therapeutic impact of topical finasteride (1-4 sprays of 0.25% topical finasteride solution daily for 12 months), oral finasteride (2.5 mg oral finasteride once daily for 12 months), and topical minoxidil (1 mL of topical minoxidil 5% twice daily for 12 months) in postmenopausal women with AGA.Methods: We conducted Bayesian network meta-analyses of individual patient-level data insofar as four clinically relevant endpoints, namely, 12-month change in (1) total hair density, (2) hair diameter, (3) clinical photographs, and (4) patients' opinion of efficacy. Data were obtained through medical charts. Regimens' surface under the cumulative ranking distribution (SUCRA) values and relative effects - as per odds ratios - were computed.Results: As per SUCRA, the most and least effective regimens - across the four outcomes - were oral finasteride, and topical finasteride, respectively; however, no significant statistical differences were found (i.e., p > 0.05).Conclusion: Oral finasteride is ranked more effective than the topical forms of minoxidil and finasteride; however, more studies are needed to confirm this result.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":"10 4","pages":"293-300"},"PeriodicalIF":1.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11299975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erratum. 勘误。

IF 1.4

Skin Appendage Disorders Pub Date : 2024-08-01 Epub Date: 2024-06-11 DOI: 10.1159/000539457

引用次数: 0

Erratum. 勘误。

IF 1.4

Skin Appendage Disorders Pub Date : 2024-08-01 Epub Date: 2024-05-23 DOI: 10.1159/000539358

引用次数: 0

Erratum. 勘误。

IF 1.4

Skin Appendage Disorders Pub Date : 2024-08-01 Epub Date: 2024-06-13 DOI: 10.1159/000539351

引用次数: 0

Erratum. 勘误。

IF 1

Skin Appendage Disorders Pub Date : 2024-06-01 Epub Date: 2024-01-25 DOI: 10.1159/000536374

引用次数: 0

Update on Squamous Cell Carcinoma of the Nail Unit: An Human Papillomavirus-Associated Condition. 指甲鳞状细胞癌的最新进展：人类乳头瘤病毒相关疾病。

IF 1

Skin Appendage Disorders Pub Date : 2024-06-01 Epub Date: 2024-03-08 DOI: 10.1159/000537760

Eric R Bray, Antonella Tosti, Brian W Morrison

引用次数: 0

Growth Factors and Microneedling in Alopecia Areata: A Narrative Review 生长因子和微针治疗脱发：叙述性综述

IF 1

Skin Appendage Disorders Pub Date : 2024-01-03 DOI: 10.1159/000534636

M. Almutlq, Abrar E. Bukhari

{"title":"Growth Factors and Microneedling in Alopecia Areata: A Narrative Review","authors":"M. Almutlq, Abrar E. Bukhari","doi":"10.1159/000534636","DOIUrl":"https://doi.org/10.1159/000534636","url":null,"abstract":"Alopecia areata (AA) is an autoimmune condition that causes non-scarring hair loss on the scalp or other hair-bearing surfaces. Various signalling molecules regulate the hair cycle and hair follicle regeneration. These include genes, growth factors, nuclear receptors, cytokines, and subcellular signalling pathways. Growth factors can cause the vascular endothelium and dermal fibroblasts to proliferate, extend the anagen phase, and delay the initiation of catagen in the hair follicle, thereby promoting hair growth. Microneedling causes the release of growth factors and has been shown to help high-molecular-weight drugs penetrate the stratum corneum and hair follicles. These recent discoveries regarding the pathogenesis of AA have resulted in the development of promising therapies. Herein, this article reviews the use of growth factors and microneedling in the treatment of AA and explores their efficacy and safety. Treatment with growth factors and microneedling appears to be highly effective for AA, with no major adverse effects, and may provide a new option for hair regeneration therapy. To support the efficacy of growth factors and microneedling for AA treatment, additional large-scale studies of patients with AA are needed.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":"33 4","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139451444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ablative CO2-Assisted Laser for Topical Drug Delivery in Nail Psoriasis: A Systematic Review 用于指甲银屑病局部给药的二氧化碳辅助烧蚀激光：系统综述

IF 1

Skin Appendage Disorders Pub Date : 2023-12-19 DOI: 10.1159/000535022

Jacopo Tartaglia, Stefano Piaserico, Luigi Naldi, Andrea Sechi

{"title":"Ablative CO2-Assisted Laser for Topical Drug Delivery in Nail Psoriasis: A Systematic Review","authors":"Jacopo Tartaglia, Stefano Piaserico, Luigi Naldi, Andrea Sechi","doi":"10.1159/000535022","DOIUrl":"https://doi.org/10.1159/000535022","url":null,"abstract":"Background: Nail psoriasis poses challenges for effective treatment, and topical drug delivery through the nail plate is limited. A novel approach to address this challenge involves the use of ablative fractional laser as a pretreatment strategy to enhance topical drug delivery for nail psoriasis. Summary: This systematic review, conducted in accordance with PRISMA guidelines, involved an extensive literature search across PubMed/MEDLINE, EMBASE, and the Cochrane Library up to July 2023. The primary focus was on exploring studies that investigated the application of ablative laser technology to augment drug delivery for nail psoriasis. Key Messages: (1) The review included seven randomized controlled trials, all examining the combination of fractional CO2 laser with topical treatments. These trials demonstrated varying degrees of improvement in nail psoriasis. (2) Patients undergoing laser treatment reported experiencing moderate levels of pain, effectively managed through the application of topical anesthesia. (3) Commonly observed side effects included erythema, swelling, and crusting, with the Koebner phenomenon being a rare occurrence. (4) Notably, patient satisfaction levels with the combined approach of laser and topical treatments were consistently high. In conclusion, the utilization of ablative CO2-assisted laser pretreatment, when used in conjunction with topical therapy, appears to be both effective and well-tolerated for the treatment of nail psoriasis. However, the establishment of optimal parameters and treatment intervals for fractional laser therapy remains an area for further research. Standardized studies are imperative to identify the most effective strategy for enhancing topical drug delivery in the context of nail psoriasis treatment.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":" 3","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138960883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Natural Treatment Options for Nail Disorders 指甲疾病的自然疗法

IF 1

Skin Appendage Disorders Pub Date : 2023-12-05 DOI: 10.1159/000534629

Daniela Baboun, Marita Yaghi, J. Keri, Brian W. Morrison

{"title":"Natural Treatment Options for Nail Disorders","authors":"Daniela Baboun, Marita Yaghi, J. Keri, Brian W. Morrison","doi":"10.1159/000534629","DOIUrl":"https://doi.org/10.1159/000534629","url":null,"abstract":"The growing demand for natural treatments has raised concerns among clinicians due to limited scientific evidence supporting their use. This review article addresses the issue by assisting dermatologists and general practitioners in recommending natural treatments for the following common nail disorders: nail brittleness, onychomycosis, periungual verrucae, paronychia, chloronychia, nail psoriasis, nail lichen planus, onychocryptosis, onycholysis, and congenital malalignment of the great toenail. One limitation is the scarcity of existing reviews on natural treatment options for nail disorders in the literature. Through a comprehensive review of existing literature, this article consolidates the available evidence on natural treatment options for these conditions. Although some natural treatments for nail disorders are supported by scientific evidence, the indiscriminate use of such remedies may lead to severe poisoning and health problems. Given the widespread and increasing use of natural treatments, clinicians play a pivotal role in educating patients about evidence-based remedies and debunking misleading claims. By doing so, clinicians can enhance patient safety and improve treatment outcomes. It is essential for healthcare professionals to be well-informed and equipped with the knowledge to differentiate between effective natural treatments and unverified claims, ensuring that patients receive appropriate care.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":"115 18","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138599543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0