Seminars in perinatology最新文献_第7页

Nutrition and the gut-brain axis in neonatal brain injury and development 营养与新生儿脑损伤和发育中的肠脑轴

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2024-08-01 DOI: 10.1016/j.semperi.2024.151927

引用次数: 0

Mesenchymal Stromal Cell therapy for Hypoxic Ischemic Encephalopathy: Future directions for combination therapy with hypothermia and/or melatonin 间充质基质细胞治疗缺氧缺血性脑病：与低温疗法和/或褪黑素联合疗法的未来方向

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2024-08-01 DOI: 10.1016/j.semperi.2024.151929

{"title":"Mesenchymal Stromal Cell therapy for Hypoxic Ischemic Encephalopathy: Future directions for combination therapy with hypothermia and/or melatonin","authors":"","doi":"10.1016/j.semperi.2024.151929","DOIUrl":"10.1016/j.semperi.2024.151929","url":null,"abstract":"<div><p>Hypoxic ischemic encephalopathy (HIE) remains a leading cause of neonatal mortality and lifelong disability across the world. While therapeutic hypothermia (HT) is beneficial, it is only partially protective and adjuvant treatments that further improve outcomes are urgently needed. In high-income countries where HT is standard care, novel treatments are tested in conjunction with HT. Mesenchymal stromal cells (MSC) represent a paradigm shift in brain protection, uniquely adapting to the host cellular microenvironment. MSC have low immunogenicity and potent paracrine effects stimulating the host tissue repair and regeneration and reducing inflammation and apoptosis. Preclinical studies in perinatal brain injury suggest that MSC are beneficial after hypoxia-ischemia (HI) and most preclinical studies of MSC with HT show protection. Preclinical and early phase clinical trials have shown that allogenic administration of MSC to neonates with perinatal stroke and HIE is safe and feasible but further safety and efficacy studies of HT with MSC in these populations are needed. Combination therapies that target all stages of the evolution of injury after HI (eg HT, melatonin and MSC) show promise for improving outcomes in HIE.</p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 5","pages":"Article 151929"},"PeriodicalIF":3.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0146000524000636/pdfft?md5=faa9a0b7c827fc4ff65b4e16d146e535&pid=1-s2.0-S0146000524000636-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141403138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Standardizing clinician training and patient care in the neonatal neurocritical care: A step-by-step guide 规范新生儿神经重症监护中的临床医生培训和患者护理：逐步指南

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2024-08-01 DOI: 10.1016/j.semperi.2024.151924

{"title":"Standardizing clinician training and patient care in the neonatal neurocritical care: A step-by-step guide","authors":"","doi":"10.1016/j.semperi.2024.151924","DOIUrl":"10.1016/j.semperi.2024.151924","url":null,"abstract":"<div><p>Neonatal neurocritical care (NNCC) has emerged as an important specialty to address neurological conditions affecting newborns including a wide spectrum of brain injuries and developmental impairment. Despite the discipline's growth, variability in NNCC service delivery, patient care, and clinical training poses significant challenges and potentially adversely impacts patient outcomes. Variations in neuroprotective strategies, postnatal care, and training methodologies highlight the urgent need for a unified approach to optimize both short- and long-term neurodevelopmental outcomes for these vulnerable population. This paper presents strategic blueprints for establishing standardized NNCC clinical care and training programs focusing on collaborative effort across medical and allied health professions. By addressing these inconsistencies, the paper proposes that standardizing NNCC practices can significantly enhance the quality of care, streamline healthcare resource utilization, and improve neurodevelopmental outcome, thus paving the way for a new era of neonatal neurological care.</p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 5","pages":"Article 151924"},"PeriodicalIF":3.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0146000524000582/pdfft?md5=a3adef20f845267e935c30a0943eba48&pid=1-s2.0-S0146000524000582-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141409336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of sleep protection in preventing and treating postpartum depression 睡眠保护在预防和治疗产后抑郁症中的作用

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2024-07-14 DOI: 10.1016/j.semperi.2024.151947

Nicole Leistikow , Milena H. Smith

引用次数: 0

Reproductive psychiatry training: A critical component of access to perinatal mental health treatment 生殖精神病学培训：获得围产期心理健康治疗的关键要素

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2024-07-14 DOI: 10.1016/j.semperi.2024.151949

Sarah Nagle-Yang , Lindsay G. Lebin , Lindsay R. Standeven , Megan Howard , Marika Toscano

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Maternal mental health as a major contributor to maternal mortality 孕产妇心理健康是导致孕产妇死亡的一个主要因素

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2024-07-14 DOI: 10.1016/j.semperi.2024.151943

Lauren A. Gimbel , Sarah J. Weingarten , Marcela C. Smid , M. Camille Hoffman

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The importance of perinatal non-birthing parents’ mental health and involvement for family health 围产期非分娩父母的心理健康和参与对家庭健康的重要性

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2024-07-14 DOI: 10.1016/j.semperi.2024.151950

Sheehan D. Fisher , Tova Walsh , Clare Wongwai

{"title":"The importance of perinatal non-birthing parents’ mental health and involvement for family health","authors":"Sheehan D. Fisher , Tova Walsh , Clare Wongwai","doi":"10.1016/j.semperi.2024.151950","DOIUrl":"10.1016/j.semperi.2024.151950","url":null,"abstract":"<div><p>Perinatal mental health research typically focuses on the birthing parent's experiences and their influence on birth/child outcomes, while not considering non-birthing parents in similar depth. Non-birthing parents are also at increased risk for mental illness during the perinatal period, and non-birthing parents’ health and involvement affect the health of birthing people, fetuses, and newborns, necessitating greater understanding of non-birthing parents’ contributions to family functioning. This review examines perinatal mental health disorders in non-birthing parents, their relationship quality with the birthing parent, and how the non-birthing parent's mental health and involvement affects the health outcomes of the birthing parent and the child. Recommendations are provided for healthcare professionals who work with perinatal patients and their families to engage non-birthing parents, learn about non-birthing parent health, and facilitate connections to care. By doing so, professionals working with perinatal patients can optimize health outcomes for their patients and the family as a whole.</p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 6","pages":"Article 151950"},"PeriodicalIF":3.2,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141717096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New treatments: Opportunities and challenges 新疗法：机遇与挑战

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2024-07-14 DOI: 10.1016/j.semperi.2024.151941

Andrew T. Drysdale , Ellen Poleshuck , MaKenzie H. Ramsey , Catherine Monk

引用次数: 0

Models of care: Opportunities and challenges 护理模式：机遇与挑战

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2024-07-14 DOI: 10.1016/j.semperi.2024.151940

Victoria Adewale , Rodolfo Fernandez-Criado , Alexandra Turco , Cynthia Battle , Ana Sofia De Brito , Emily Feinberg , Emily S Miller

引用次数: 0

A systematic review of community-based interventions to address perinatal mental health 对基于社区的围产期心理健康干预措施的系统性审查

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2024-07-14 DOI: 10.1016/j.semperi.2024.151945

Jihye Kim Scroggins , Sarah E. Harkins , Sevonna Brown , Victoria St. Clair , Guramrit K. LeBron , Veronica Barcelona

{"title":"A systematic review of community-based interventions to address perinatal mental health","authors":"Jihye Kim Scroggins , Sarah E. Harkins , Sevonna Brown , Victoria St. Clair , Guramrit K. LeBron , Veronica Barcelona","doi":"10.1016/j.semperi.2024.151945","DOIUrl":"10.1016/j.semperi.2024.151945","url":null,"abstract":"<div><p><span><span><span>Little is known about the scope and effectiveness of community-based interventions to address maternal perinatal mental health in the US. We searched PubMed, </span>CINAHL, and </span>PsychINFO<span> in January 2024 to conduct a systematic review<span> of studies using community-based interventions for maternal mental health from pregnancy to 1 year postpartum in the US. We reviewed 22 quantitative studies, and assessed methodological quality and effectiveness of interventions. Most were randomized trials (</span></span></span><em>n</em> = 16) with strong or good methodological quality. The majority of the studies included racially and ethnically diverse participants (<em>n</em><span><span> = 14), delivered interventions through community health workers, nurses, midwives, and </span>doulas (</span><em>n</em> = 18), and had mixed effectiveness of interventions (<em>n</em><span> = 14). Limitations included small sample sizes, interventions not specifically developed for mental health, limited community involvement in designing interventions, and focus on participants with no mental health issues. Community partners augment this review with lived experience and recommendations for research and clinical practice.</span></p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 6","pages":"Article 151945"},"PeriodicalIF":3.2,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141691871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0