Elizabeth Werner , Huynh-Nhu Le , Vanessa Babineau , Myrriam Grubb
{"title":"Preventive interventions for perinatal mood and anxiety disorders: A review of selected programs","authors":"Elizabeth Werner , Huynh-Nhu Le , Vanessa Babineau , Myrriam Grubb","doi":"10.1016/j.semperi.2024.151944","DOIUrl":"10.1016/j.semperi.2024.151944","url":null,"abstract":"<div><p>Perinatal mood and anxiety disorders (PMADs) have high prevalence rates and profound deleterious effects on birthing people, families, and society. Counseling interventions have been shown to be effective and carry minimal risk. We review here the protocols and clinical trial data of four preventive counseling interventions that are effective at preventing PMADs. We present the Mothers and Babies (MB) program, a cognitive-behavioral preventive intervention, and Reach Out, Stay Strong, Essentials for mothers of newborns (ROSE), an interpersonal psychotherapy preventive intervention. We also present Mindfulness-Based Cognitive Therapy for Perinatal Depression (MBCT- PD), a preventive intervention that combines a cognitive-behavioral and mindfulness-based approach, and Practical Resources for Effective Postpartum Parenting (PREPP), a parent-infant dyadic intervention with psychodynamic, cognitive-behavioral, mindfulness-based, and psychoeducational elements. We recommend that screening for risk of PMADs (not just current mood symptoms) and providing preventive interventions to those at risk should be included as part of standard obstetrics care.</p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 6","pages":"Article 151944"},"PeriodicalIF":3.2,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0146000524000788/pdfft?md5=97046687118be61c17be24674315f2e8&pid=1-s2.0-S0146000524000788-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141693705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M.T. van Dijk , A. Talati , P. Gonzalez Barrios , A.J. Crandall , C. Lugo-Candelas
{"title":"Prenatal depression outcomes in the next generation: A critical review of recent DOHaD studies and recommendations for future research","authors":"M.T. van Dijk , A. Talati , P. Gonzalez Barrios , A.J. Crandall , C. Lugo-Candelas","doi":"10.1016/j.semperi.2024.151948","DOIUrl":"10.1016/j.semperi.2024.151948","url":null,"abstract":"<div><p><span>Prenatal depression, a common pregnancy-related risk with a prevalence of 10–20 %, may affect </span><em>in</em><span><span> utero development and socioemotional and neurodevelopmental outcomes in the next generation. Although there is a growing body of work that suggests prenatal depression has an independent and long-lasting effect on offspring outcomes, important questions remain, and findings often do not converge. The present review examines work carried out in the last decade, with an emphasis on studies focusing on mechanisms and leveraging innovative technologies and study designs to fill in gaps in research. Overall, the past decade of research continues to suggest that prenatal depression increases risk for offspring socioemotional problems and may alter early brain development by affecting maternal-fetal physiology during pregnancy. However, important limitations remain; lack of diversity in study samples, inconsistent consideration of potential confounders (e.g., genetics, postnatal depression, parenting), and restriction of examination to narrow time windows and single exposures. On the other hand, exciting work has begun uncovering potential mechanisms underlying transmission, including alterations in mitochondria functioning, </span>epigenetics<span>, and the prenatal microbiome. We review the evidence to date, identify limitations, and suggest strategies for the next decade of research to detect mechanisms as well as sources of plasticity and resilience to ensure this work translates into meaningful, actionable science that improves the lives of families.</span></span></p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 6","pages":"Article 151948"},"PeriodicalIF":3.2,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141695787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The parental brain, perinatal mental illness, and treatment: A review of key structural and functional changes","authors":"Jodi L. Pawluski","doi":"10.1016/j.semperi.2024.151951","DOIUrl":"10.1016/j.semperi.2024.151951","url":null,"abstract":"<div><p>The transition to parenthood is perhaps the only time in adult life when the brain changes to such a significant degree in such a short period, particularly in birthing parents. It is also a time when there is an increased risk of developing a mental illness, which may be due, in part, to the increased neuroplasticity. Thus, we must develop interventions and treatments that support parents and promote parental brain health. This review will highlight key findings from current research on how human brain structure and function are modified with 1) the transition to parenthood, 2) parenting stress and perinatal mental illness, and 3) treatments aimed at promoting perinatal mental health. The focus will be on birthing parents and mothers, but brain changes in non-birthing parents will also be discussed. Improvements in our understanding of the parental brain, in health and with illness, will promote the well-being of generations to come.</p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 6","pages":"Article 151951"},"PeriodicalIF":3.2,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0146000524000855/pdfft?md5=5eb38f80e2f6aa91275be2ef10d6ecfe&pid=1-s2.0-S0146000524000855-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141707330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claire A Wilson , Margaret Bublitz , Prabha Chandra , Sarah Hanley , Simone Honikman , Sarah Kittel-Schneider , Sarah Cristina Zanghellini Rückl , Patricia Leahy-Warren , Nancy Byatt
{"title":"A global perspective: Access to mental health care for perinatal populations","authors":"Claire A Wilson , Margaret Bublitz , Prabha Chandra , Sarah Hanley , Simone Honikman , Sarah Kittel-Schneider , Sarah Cristina Zanghellini Rückl , Patricia Leahy-Warren , Nancy Byatt","doi":"10.1016/j.semperi.2024.151942","DOIUrl":"10.1016/j.semperi.2024.151942","url":null,"abstract":"<div><p>Perinatal mental health care differs around the world. We provide a global perspective on the current status of service provision, barriers and facilitators to access, and strategies to improve access in high-income and low- and middle-income countries across five continents (Asia, Africa, Europe, North America and South America). Many of the countries considered do not have universal healthcare coverage. This poses a challenge to perinatal mental health care access. However, there are other social and structural barriers to access, including stigma and other sources of marginalization and discrimination. Yet there are opportunities discussed herein to learn more about what perinatal mental health services work for what populations* and in what circumstances, by adopting a global lens to examine innovative solutions utilized across geographical settings.</p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 6","pages":"Article 151942"},"PeriodicalIF":3.2,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0146000524000764/pdfft?md5=1c0630f962b29fc8085ec12ccbd20e77&pid=1-s2.0-S0146000524000764-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141693853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perinatal mental health: Research that moves the agenda forward","authors":"Lauren M. Osborne , Catherine Monk","doi":"10.1016/j.semperi.2024.151952","DOIUrl":"10.1016/j.semperi.2024.151952","url":null,"abstract":"","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 6","pages":"Article 151952"},"PeriodicalIF":3.2,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141703479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christina Pardo , Breanna Watson , Olga Pinkhasov , Aimee Afable
{"title":"Social determinants of perinatal mental health","authors":"Christina Pardo , Breanna Watson , Olga Pinkhasov , Aimee Afable","doi":"10.1016/j.semperi.2024.151946","DOIUrl":"10.1016/j.semperi.2024.151946","url":null,"abstract":"<div><p>Social inequities and mental health are public health and medical conditions that are inextricably linked. Perinatal mental health is influenced by social, physical, and biological factors, with additional stressors related to pregnancy. The social determinants of health (SDOH) encompasses all conditions in which people live and grow, inclusive of cultural norms that reflect the diverse populations we serve. To best understand the mechanisms by which the SDOH affects perinatal mental health, we introduce the Urban Stress Model and describe the link between urban realities to stress response and potential mechanisms that link urban living to increased risk of adverse perinatal mental health. Given the increased diversity of patient populations, cultural considerations are paramount in understanding the utility and best practices in screening and interventions among ethnically diverse communities. Building on our Urban Stress Model and a structural determinants of health framework, we present examples of interventions to address the social inequities of perinatal mental health from the policy to community levels.</p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 6","pages":"Article 151946"},"PeriodicalIF":3.2,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141716984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jourdan E. Triebwasser, Jill K. Davies, Ajleeta Nestani
{"title":"COVID-19 therapeutics for the pregnant patient","authors":"Jourdan E. Triebwasser, Jill K. Davies, Ajleeta Nestani","doi":"10.1016/j.semperi.2024.151920","DOIUrl":"10.1016/j.semperi.2024.151920","url":null,"abstract":"<div><p>SARS-CoV-2 infection can cause severe disease among pregnant persons. Pregnant persons were not included in initial studies of therapeutics for COVID-19, but cumulative experience demonstrates that most are safe for pregnant persons and the fetus, and effective for prevention or treatment of severe COVID-19.</p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 4","pages":"Article 151920"},"PeriodicalIF":3.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141311631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dustin D. Flannery , Neil C. Shah , Karen M. Puopolo
{"title":"Perinatal COVID-19: Implications for care of the newborn","authors":"Dustin D. Flannery , Neil C. Shah , Karen M. Puopolo","doi":"10.1016/j.semperi.2024.151921","DOIUrl":"10.1016/j.semperi.2024.151921","url":null,"abstract":"<div><p>The maternal/newborn dyad presents special challenges to infection management. Early in the COVID-19 pandemic, lack of information regarding SARS-CoV-2 transmission and virulence made it difficult to develop appropriate care guidance when pregnant persons had COVID-19 at the time of presentation for childbirth. We will review the considerations for the parturient, newborn, and care team, and describe the evolution of perinatal COVID management guidance.</p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 4","pages":"Article 151921"},"PeriodicalIF":3.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141318255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neonatal-perinatal collaboration during the COVID-19 pandemic","authors":"Miller K , Kimberlin DW , Arora N , Puopolo KM","doi":"10.1016/j.semperi.2024.151918","DOIUrl":"10.1016/j.semperi.2024.151918","url":null,"abstract":"<div><p>The COVID-19 pandemic required perinatal clinicians to address the individual medical needs of the pregnant person and the fetus as well as the interdependent considerations of the maternal/newborn dyad. Regional, national and international collaborative groups utilized existing structures and in some cases, formed new partnerships to rapidly collect perinatal information. The urgent need to care for at-risk and infected pregnant persons required these groups to develop practical approaches to collect the data needed to safely inform practice. Here we will summarize the findings of five collaborative studies that leveraged differing methods to inform perinatal pandemic care.</p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 4","pages":"Article 151918"},"PeriodicalIF":3.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amanda Li , David A. Schwartz , Andrew Vo , Roslyn VanAbel , Celeste Coler , Edmunda Li , Bryan Lukman , Briana Del Rosario , Ashley Vong , Miranda Li , Kristina M. Adams Waldorf
{"title":"Impact of SARS-CoV-2 infection during pregnancy on the placenta and fetus","authors":"Amanda Li , David A. Schwartz , Andrew Vo , Roslyn VanAbel , Celeste Coler , Edmunda Li , Bryan Lukman , Briana Del Rosario , Ashley Vong , Miranda Li , Kristina M. Adams Waldorf","doi":"10.1016/j.semperi.2024.151919","DOIUrl":"10.1016/j.semperi.2024.151919","url":null,"abstract":"<div><p>Pregnant people and their fetuses are vulnerable to adverse health outcomes from coronavirus 2019 disease (COVID-19) due to infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 has been associated with higher rates of maternal mortality, preterm birth, and stillbirth. While SARS-CoV-2 infection of the placenta and vertical transmission is rare, this may be due to the typically longer time interval between maternal infection and testing of the placenta and neonate. Placental injury is evident in cases of SARS-CoV-2-associated stillbirth with massive perivillous fibrin deposition, chronic histiocytic intervillositis, and trophoblast necrosis. Maternal COVID-19 can also polarize fetal immunity, which may have long-term effects on neurodevelopment. Although the COVID-19 pandemic continues to evolve, the impact of emerging SARS-CoV-2 variants on placental and perinatal injury/mortality remains concerning for maternal and perinatal health. Here, we highlight the impact of COVID-19 on the placenta and fetus and remaining knowledge gaps.</p></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"48 4","pages":"Article 151919"},"PeriodicalIF":3.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141389626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}