Seminars in perinatology最新文献_第8页

Prenatal genomic sequencing: Navigating uncertainty 产前基因组测序：导航不确定性

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2025-04-01 DOI: 10.1016/j.semperi.2025.152058

Médéric Jeanne , Wendy K. Chung

引用次数: 0

Supporting patient autonomy through respectful labor and childbirth healthcare services 通过尊重分娩和分娩保健服务，支持患者自主

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2025-04-01 DOI: 10.1016/j.semperi.2025.152048

Kristin P. Tully , Rose L. Molina , Johanna Quist-Nelson , Lisa Wangerien , Kanika Harris , Amber L. Weiseth , Joyce K. Edmonds

{"title":"Supporting patient autonomy through respectful labor and childbirth healthcare services","authors":"Kristin P. Tully , Rose L. Molina , Johanna Quist-Nelson , Lisa Wangerien , Kanika Harris , Amber L. Weiseth , Joyce K. Edmonds","doi":"10.1016/j.semperi.2025.152048","DOIUrl":"10.1016/j.semperi.2025.152048","url":null,"abstract":"<div><div>Despite childbirth being a leading cause of hospitalization, the system of care has not been optimized for patients in the United States. Rates of maternal mortality are high, increasing, and disproportionate. In addition to disparities in health outcomes, the quality of perinatal care, as assessed by patient experiences of care, is variable. Although clinicians strive to actively support families through labor and childbirth, various forms of mistreatment are common in perinatal care. Such instances of patient mistreatment highlight an urgent need to further enact respectful maternity care principles so that services are more person-focused and supportive. Welcoming clinical environments with relationship-centered care, trauma-informed interactions, and anti-racist practices support maternal autonomy. As a part of these quality care approaches, effective communication by clinicians helps patients understand their healthcare options and the events that shape their childbirth experiences. Nonstigmatizing interactions, using linguistically and culturally appropriate language, and integrating tools for shared decision making are essential elements of quality intrapartum care. A reproductive justice lens focuses attention on the need to eliminate infringements on health and build assurances to enable positive health outcomes and thriving.</div></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 3","pages":"Article 152048"},"PeriodicalIF":3.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144108087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Melanoma in pregnancy 妊娠期黑色素瘤

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2025-03-01 DOI: 10.1016/j.semperi.2025.152040

Christina S. Oh , Elizabeth F. Sher , Amy K. Bieber

引用次数: 0

Cervical cancer in pregnancy 妊娠期子宫颈癌

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2025-03-01 DOI: 10.1016/j.semperi.2025.152038

Charlotte LeJeune , Nathalia Mora-Soto , Lone Storgaard , René Pareja , Frédéric Amant

引用次数: 0

Obstetric and perinatal management in the setting of cancer 癌症背景下的产科和围产期管理

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2025-03-01 DOI: 10.1016/j.semperi.2025.152044

Eve Overton , Gabriela Tessler

引用次数: 0

Thyroid cancer 甲状腺癌

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2025-03-01 DOI: 10.1016/j.semperi.2025.152042

Liyang Tang , Trevor E Angell

引用次数: 0

Lymphoma and leukemia occurring during pregnancy 怀孕期间发生的淋巴瘤和白血病

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2025-03-01 DOI: 10.1016/j.semperi.2025.152041

Adam S. Zayac, Ogechukwu Egini, Neil D. Palmisiano, Andrew M. Evens

{"title":"Lymphoma and leukemia occurring during pregnancy","authors":"Adam S. Zayac, Ogechukwu Egini, Neil D. Palmisiano, Andrew M. Evens","doi":"10.1016/j.semperi.2025.152041","DOIUrl":"10.1016/j.semperi.2025.152041","url":null,"abstract":"<div><div>Malignancies arising during pregnancy are an infrequent occurrence, leading to a paucity of data on the optimal management of cancers during pregnancy. Unlike most solid tumors, the primary, and often curative, management of hematologic malignancies relies heavily on multiagent cytotoxic chemotherapies over surgery and other localized therapies, making their management during pregnancy even more complex and hazardous to both mother and fetus. Close multidisciplinary care and coordination between obstetrician, maternal fetal medicine, and oncologists are essential given the dangers to both in the management, from diagnosis and throughout treatment, even through delivery and survivorship. Due to the importance of this topic and the number of lives that could be impacted, guidelines have been published by interdisciplinary expert panels based on available data and clinical experience. This review addresses the management of both Hodgkin and non-Hodgkin lymphomas as well as acute and chronic leukemias. The optimal diagnostic approaches, and therapeutic schemes, including the use of cellular therapies, immunotherapies, targeted and cytotoxic agents, as well as guidance on decision making regarding management of the pregnancy weighing both the maternal and fetal risks and benefits of each approach are discussed herein.</div></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 2","pages":"Article 152041"},"PeriodicalIF":3.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143610738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends and outcomes associated with cancer diagnoses during delivery hospitalizations 分娩住院期间与癌症诊断相关的趋势和结果

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2025-03-01 DOI: 10.1016/j.semperi.2025.152046

Timothy Wen , Madeleine G. Fish , Alexander M. Friedman

引用次数: 0

Immune checkpoint inhibitors and pregnancy: Considerations for treating medically complex patients with the best available therapy 免疫检查点抑制剂与妊娠：用最佳可用疗法治疗复杂患者的考虑

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2025-03-01 DOI: 10.1016/j.semperi.2025.152045

Elad Sharon

{"title":"Immune checkpoint inhibitors and pregnancy: Considerations for treating medically complex patients with the best available therapy","authors":"Elad Sharon","doi":"10.1016/j.semperi.2025.152045","DOIUrl":"10.1016/j.semperi.2025.152045","url":null,"abstract":"<div><div>In recent decades, the mean age of childbearing has increased in the United States and other developed countries, coinciding with a rise in cancer diagnoses during pregnancy. This trend is partly due to the increased use of assisted reproductive technologies and a decrease in the mean age of cancer onset for several malignancies. Concurrently, immune checkpoint inhibitors (ICIs) have become a standard treatment for various cancers, yet their safety during pregnancy remains under-researched. This article explores the complex intersection of cancer treatment and pregnancy, focusing on the use of ICIs. Despite societal concerns, data on the safety of ICIs during pregnancy are limited, primarily derived from preclinical animal studies and case reports. While most case reports suggest no significant adverse effects on live births, isolated incidents of severe neonatal complications have been documented. The potential for immune-related adverse events (irAEs) in neonates, such as thyroiditis or enterocolitis, underscores the need for caution. Given the lack of comprehensive data, clinicians face challenging decisions when treating pregnant cancer patients, particularly in metastatic settings where ICIs may be the only viable option. This article advocates for a careful risk-benefit analysis and informed patient discussions, emphasizing the need for further research to guide clinical decision-making in these complex scenarios.</div></div>","PeriodicalId":21761,"journal":{"name":"Seminars in perinatology","volume":"49 2","pages":"Article 152045"},"PeriodicalIF":3.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143610742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ovarian cancer in pregnancy 妊娠期卵巢癌

IF 3.2 3区医学

Seminars in perinatology Pub Date : 2025-03-01 DOI: 10.1016/j.semperi.2025.152043

Jennifer R. Jorgensen , Molly A. Brewer , Carolyn D. Runowicz

引用次数: 0