Sensors International最新文献

{"title":"Wireless temperature calibration for medical centrifuge","authors":"Tianyu Zhu ,&nbsp;Ju Lu ,&nbsp;Jian Shen ,&nbsp;Jie Liu ,&nbsp;Xinqing Xiao","doi":"10.1016/j.sintl.2024.100296","DOIUrl":"10.1016/j.sintl.2024.100296","url":null,"abstract":"<div><p>Based on the complexity and metrological requirements of temperature calibration within the rotor of a medical low-temperature centrifuge, a wireless temperature calibration device for medical centrifuges has been designed and developed. The temperature probe is integrated into the centrifuge tube, and the entire device can be placed inside the rotor of the centrifuge, allowing for the measurement and analysis of the actual temperature of the test solution inside the centrifuge tube under dynamic rotation conditions. Furthermore, the force situation during dynamic calibration is analyzed and performance tested. The calibration device can consistently and dependably achieve dynamic temperature data acquisition under high-speed conditions of medical low-temperature centrifuges, facilitating dynamic temperature calibration within the centrifuge rotor and offering support for centrifuge temperature control processes.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100296"},"PeriodicalIF":0.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351124000184/pdfft?md5=082303b4d730f38f5435b6ecd2576988&pid=1-s2.0-S2666351124000184-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142117262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of varied oleic acid-coated Fe3O4 nanoparticles using the co-precipitation technique for biosensor applications","authors":"Helendra ,&nbsp;Nurul Imani Istiqomah ,&nbsp;Harsojo Sabarman ,&nbsp;Edi Suharyadi","doi":"10.1016/j.sintl.2024.100295","DOIUrl":"10.1016/j.sintl.2024.100295","url":null,"abstract":"<div><div>This study successfully synthesized oleic acid (OA)-coated Fe₃O₄ nanoparticles using the coprecipitation method for the needs of biosensor applications, as shown through the characterization of structure and morphology using XRD and TEM. This observation used 0.75 ml of OA (Fe₃O₄-OA(0.75)) and 1.25 ml of OA (Fe₃O₄-OA(1.25). A decrease in particle size distribution from 18.55 nm to 16.30 nm was observed, which means a reduction in agglomeration and increased dispersibility. Vibrating Sample Magnetometer (VSM) observations showed that the saturation magnetization of Fe₃O₄ particles modified with OA decreased from 47.71 emu/g to 45.90 emu/g at Fe₃O₄-OA(0.75) and decreased again to 42.29 emu/g at Fe₃O₄-OA(1.25). But they all show soft ferromagnetic properties with very low coercivity, making them suitable for Giant Magnetoresistance (GMR) biosensor applications. A series of concentrations in ethanol solution were performed to evaluate the detection sensitivity of GMR for these pure and oleic acid-modified Fe₃O₄ samples. Concentrations of 2, 5, 10, 15, 25, and 35 mg/ml were integrated at 2 μL each onto the surface of the GMR chip. A decrease in sensitivity was observed due to the change in saturation. Pure Fe₃O₄ with a sensitivity of 5.07 mV (mg/ml) decreased to 4.49 mV (mg/ml) and 3.35 mV (mg/ml) after oleic acid coating. Thus, although adding a proportional amount of oleic acid can slightly decrease the saturation magnetization, it can be a valuable method for applications such as GMR biosensors that demand high dispersibility and sensitivity that remains strong.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100295"},"PeriodicalIF":0.0,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351124000172/pdfft?md5=27f840d98140cf4ee2740134943de20e&pid=1-s2.0-S2666351124000172-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142312633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution of SnO2 nanoparticles for the electrochemical sensing of dopamine including photocatalytic toxic dyes degradation","authors":"S.R. Kiran Kumar ,&nbsp;Harisha S ,&nbsp;Jalaja P ,&nbsp;B.K. Jayanna ,&nbsp;K. Yogesh Kumar ,&nbsp;M.S. Anantha","doi":"10.1016/j.sintl.2023.100278","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100278","url":null,"abstract":"<div><p>In the present study, SnO₂ nanoparticles were synthesized, and their structural features were evaluated by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX) and transmission electron microscopy (TEM) techniques. Modified electrodes (MCPE) were prepared and utilized to access the electrochemical behaviour of dopamine. This study was conducted in a phosphate buffer solution with a pH value of 7.2. The results indicate that the modified carbon paste electrode (MCPE), with a high active surface area, exhibited excellent electrochemical sensing properties and demonstrated good reproducibility and high sensitivity for the electrochemical determination of DA. Potentially interfering compounds were tested at the surface of the proposed sensor, confirming that, they did not interfere with the determination of DA under optimum condition. Additionally, the photocatalytic properties of SnO₂ were evaluated in degradation of cationic and anionic dyes. It was concluded that the higher photocatalytic activity in SnO₂ nanocomposites was attributed to their porosity and high surface area.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100278"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351123000529/pdfft?md5=fe8198267d52c9ea6876da508bce1d60&pid=1-s2.0-S2666351123000529-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139434488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabrication and performance of capacitive humidity and strain sensors that incorporate 3D-printed nanocomposite electrodes","authors":"Stefanos Matsalis ,&nbsp;George Paterakis ,&nbsp;Nikos Koutroumanis ,&nbsp;George Anagnostopoulos ,&nbsp;Costas Galiotis","doi":"10.1016/j.sintl.2023.100272","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100272","url":null,"abstract":"<div><p>This work reports on advances in capacitive humidity and strain sensor technologies through the development of state-of-the-art 3D-printed Interdigitated Electrodes (IDEs) coated with a unique GO/ PVA coating. These IDEs are constructed using a novel composite filament of MWCNTs and polylactic acid (PLA) that offer superior flexural strength and electrical properties compared to conventional polymer matrices.</p><p>We show that the GO/ PVA coating appears to be sensitive over the full range of relative humidity (RH) from 0% to 100%, with a remarkable capacitance change of 300 pF/%RH. Fast response and recovery times of 60 and 42 s, respectively, have been measured outperforming existing works that utilize metal electrodes. Regarding temperature dependence, the coatings endure conditions ranging from ambient to −25 °C, even in the presence of ice. Furthermore, at 50% RH, the sensors are shown to achieve a maximum sensitivity of 34.2 within a strain range of up to 2%.</p><p>In conclusion, this work represents a significant advancement in cutting-edge sensor technologies, offering unprecedented capabilities for humidity and strain sensing performance for a wide range of applications.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100272"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351123000463/pdfft?md5=c7ef57bf23c7d5c0e5d05b7f92cee431&pid=1-s2.0-S2666351123000463-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139108815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thank you Note for Reviewers","authors":"","doi":"10.1016/S2666-3511(24)00042-1","DOIUrl":"10.1016/S2666-3511(24)00042-1","url":null,"abstract":"","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100320"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly efficient enzyme less glucose sensor based on cross-linked nitrogen-doped graphene aerogel incorporated with ytterbium oxide and decorated with nickel nitride nanoparticles","authors":"Mohammad Mazloum-Ardakani,&nbsp;Negar Shaker-Ardakani,&nbsp;Fatemeh Farbod","doi":"10.1016/j.sintl.2024.100290","DOIUrl":"10.1016/j.sintl.2024.100290","url":null,"abstract":"<div><p>The development of valuable Non-enzymatic glucose sensors relies extensively on the design of sensitive and cost-effective materials with high catalytic activity for the efficient electro-oxidation of glucose. In this work, nitrogen-doped reduced graphene aerogel decorated with Yb₂O₃ nanoparticles (GA:N–Yb₂O₃) was prepared via a simple one-step hydrothermal method. Then this conductive porous three-dimensional scaffold was employed as an excellent substrate for hosting nickel nitride (Ni₃N) nanoparticles (NPs). Electrochemical investigation confirmed the beneficial role of GA:N–Yb₂O₃ for enhancing Ni₃N NPs catalytic activity. This sensor shows low glucose oxidation potential, a low detection limit, and high sensitivity. Using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), chronoamperometry, and amperometry, the electrochemical activity of the electrode towards the oxidation of glucose was investigated. The GA:N–Yb₂O₃/Ni₃N glassy carbon electrode (GCE) modifier was well applied as an electrocatalyst for sensing glucose with the detection limit of 3.9 μM, and the sensitivity of 247.1 μA mM⁻¹cm⁻². Impressively, ascorbic acid, acetaminophen, dopamine, uric acid, and sodium chloride oxidation interference could also be avoided. Nonetheless, the selectivity and stability of the Non-enzymatic glucose sensors were quite good. Hence, this new Non-enzymatic sensor can have a reliable potential application in glucose detection.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100290"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351124000123/pdfft?md5=71b3847bd22a899b5978fff2d68597b8&pid=1-s2.0-S2666351124000123-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141978972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficiency of three dimension Au–MnO2 nanostructure as visible adsorption based detector of histamine sensing","authors":"Siti Febtria Asrini Sugito ,&nbsp;Mochamad Zakki Fahmi ,&nbsp;Miratul Khasanah ,&nbsp;Septianti Putri Sophiar ,&nbsp;Jia-yaw Chang ,&nbsp;Gasidit Panomsuwan","doi":"10.1016/j.sintl.2023.100275","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100275","url":null,"abstract":"<div><p>High intakes of histamine are poisonous. Hence, determining histamine levels in fisheries and processed products is essential to food quality. Several colorimetric sensors based on gold nanoparticles have shown exemplary performance in detecting the presence of histamine in samples. The modified AuNPs by MnO₂ were used as a reagent in histamine analysis by UV–Vis spectrophotometry. Using a seed-mediated growth method, modified Au–MnO2 nanostructures were synthesized from citrate-coated AuNPs and KMnO4. The Au–MnO₂ nanostructure synthesis process produced a yellow-green solution, which produced a crystalline solid with a particle size &lt;100 nm by evaporation. These nanoparticles comprise AuNPs and MnO₂ components, which still perform their original properties. Application of Au–MnO₂ nanostructure in histamine spectrophotometry has values in sensitivity of 0.0344 ppm, detection limit of 0.185 ppm, quantification limit of 0.618 ppm, and accuracy of 95–101 %. Based on analytical results, the effectiveness of synthesizing Au–MnO₂ nanostructure to form complexes with histamine content was low, and it was due to the weak binding between the imidazole group of histamine and Au–MnO₂ nanostructures. Therefore, further investigation on the composition of the Mn metal or the selection of other metals is needed to use Au–MnO₂ as candidate histamine biosensors.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100275"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351123000499/pdfft?md5=e517f7eb23a6be945a661be6ad79921c&pid=1-s2.0-S2666351123000499-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139099872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial biotechnology alchemy: Transforming bacterial cellulose into sensing disease- A review","authors":"Ali Jawad Akki ,&nbsp;Pratheek Jain ,&nbsp;Ravindra Kulkarni ,&nbsp;Raghavendra Rao Badkillaya ,&nbsp;Raghavendra V. Kulkarni ,&nbsp;Farhan Zameer ,&nbsp;V Raghu Anjanapura ,&nbsp;Tejraj M. Aminabhavi","doi":"10.1016/j.sintl.2023.100277","DOIUrl":"10.1016/j.sintl.2023.100277","url":null,"abstract":"<div><p>Biosensors have the potential to revolutionize healthcare by providing rapid and accurate diagnosis of diseases. Biosensors are analytical devices that convert molecular recognition of a target analyte into a measurable signal. Older diagnostic techniques, such as immunoaffinity column assays, fluorometric, and enzyme-linked immunosorbent assays, are laborious, require qualified personnel, and can be time consuming. In contrast, biosensors offer improved accuracy, sustainability, and rapidness due to their ability to detect specific biomarkers with high sensitivity and specificity. The review covers various bacterial cellulose (BC)-based biosensors, from SARS-CoV-2 detection to wearable health monitoring and interaction with human-computer interfaces. BC's integration into ionic thermoelectric hydrogels for wearable health monitoring shows its potential for real-time health tracking. Incorporating BC in biosensors for low-noise electrodes, and wearable sensors has been elaborated. The invention of a phage-immobilized BC biosensor for <em>S. aureus</em> detection is a significant contribution to the field, highlighting the biosafety and efficiency of BC in pathogen identification and demonstrating BC's versatility across multiple sensing platforms. Palladium nanoparticle-bacterial cellulose hybrid nanofibers show excellent electrocatalytic activity for dopamine detection, whereas Au-BC nanocomposite biosensors show efficacy in glucose detection, with potential therapeutic applications. The “lab-on-nanopaper” device, utilizing BC nanopaper, not only visually detects human serum albumin but also establishes itself as a new-generation optical biosensing platform with superiority over conventional substrates. This review contributes to the ongoing advancements in biosensor technology, highlighting the potential of BC as a versatile material for developing innovative biosensors. This is crucial for improving the accuracy, sensitivity, and efficiency of diagnostic tools in healthcare.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100277"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351123000517/pdfft?md5=0a29febd19392e655bf105d6de924aba&pid=1-s2.0-S2666351123000517-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139394471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green synthesis of metal nanoparticles, characterization, and biosensing applications","authors":"Chiravoot Pechyen ,&nbsp;Benchamaporn Tangnorawich ,&nbsp;Surachet Toommee ,&nbsp;Robert Marks ,&nbsp;Yardnapar Parcharoen","doi":"10.1016/j.sintl.2024.100287","DOIUrl":"10.1016/j.sintl.2024.100287","url":null,"abstract":"<div><p>This comprehensive review provides an in-depth overview of the green (biological) synthesis, characterization, and biosensor applications of metal nanoparticles (NPs). Because of their unique physical and chemical properties, high surface area, and nanoscale size, NPs have become crucial in various fields. The review emphasizes the synthesis, properties, and applications of several metal NPs, particularly silver (AgNPs), gold (AuNPs), platinum (PtNPs), copper (CuNPs), zinc oxide (ZnONPs), iron oxide (FeONPs), and palladium (PdNPs). Green synthesis methods, a truly innovative approach, utilize biological substances such as plant extracts, bacteria, fungi, and yeast. These methods offer environmentally friendly and biologically compatible alternatives to conventional chemical synthesis techniques. This review details these sustainable approaches and their advantages over traditional methods. These natural sources provide an abundant, cost-effective, and environmentally sustainable alternative for NP production. The importance of thorough characterization of nanoparticles is also discussed, highlighting techniques such as transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and UV–Vis spectroscopy to analyze the size, shape, surface properties, structural integrity, and optical behavior of the NPs. The review highlights the vast potential of metal NPs in biosensors, which play a critical role in medical diagnostics, environmental monitoring, and food safety. Incorporating metal NPs in electrochemical, optical, thermometric, and piezoelectric biosensors significantly enhances sensitivity and specificity, enabling rapid and real-time detection of various analytes.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100287"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351124000093/pdfft?md5=57bfca1c9b467e34681fe771783aab61&pid=1-s2.0-S2666351124000093-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141961170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macro world in nano hands: Nano revolutions in medicine and food processing with the aid of nanosensors","authors":"Gayatri Kotekar ,&nbsp;Sucheta Gaikwad ,&nbsp;Anukriti Nigam","doi":"10.1016/j.sintl.2024.100291","DOIUrl":"10.1016/j.sintl.2024.100291","url":null,"abstract":"<div><p>Nanotechnology, the manipulation of materials at the nanoscale, has emerged as a transformative force with profound implications for diverse fields. This following review explores the versatile administration of nanotechnology in both the biomedical and food processing disciplines, highlighting the potential breakthroughs and advancements achieved in these critical domains. Nanotechnology has made significant advancements in drug delivery, imaging, and diagnostics possible in the biomedical field. Particular characteristics of nanoscale materials, like nanoparticles and nanocarriers, improve their compatibility with biological systems. As a result, targeted drug delivery systems have been created, enabling precise drug administration and fewer side effects. Furthermore, improved diagnostic capabilities are made possible by nanoscale imaging agents, which allow for early disease detection. Additionally, the development of nanosensors for the real-time tracking of physiological variables has been made possible by nanotechnology, which has aided in the rise of personalized medicine. Nanotechnology has completely changed a number of aspects of the food processing industry, including packaging, preservation, and food safety. Antimicrobial nanomaterials have been used to put an end to the growth of harmful microorganisms, thus increasing food safety. Additionally, food packaging using nanocomposites has shown to have enhanced barrier qualities, extending the shelf life of perishable items and cutting down on food waste. The creation of intelligent packaging systems that can continuously check the freshness of food is made possible by nanoscale materials. The use of nanotechnology in these fields presents ethical and safety issues, despite its enormous potential. In order to ensure the responsible integration of nanotechnology into biomedical and food processing practices, ongoing research is devoted to addressing these challenges. The ongoing investigation of nanotechnology's potential in these fields offers hope for the development of safer, more effective, and technologically sophisticated solutions that will improve human health and welfare.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100291"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351124000135/pdfft?md5=8175decfa8146c3398fa283f37d48746&pid=1-s2.0-S2666351124000135-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142011597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}