Sensors International最新文献

Analytical model for DG-AlGaN/GaN MOS-HEMT for sensitive analysis of pH analytes and charged biomolecules 用于灵敏分析 pH 值分析物和带电生物分子的 DG-AlGaN/GaN MOS-HEMT 分析模型

Sensors International Pub Date : 2024-11-22 DOI: 10.1016/j.sintl.2024.100312

P. Sriramani , N. Mohankumar , Lignesh Durai , Y. Prasamsha , Nitin Rakesh

{"title":"Analytical model for DG-AlGaN/GaN MOS-HEMT for sensitive analysis of pH analytes and charged biomolecules","authors":"P. Sriramani , N. Mohankumar , Lignesh Durai , Y. Prasamsha , Nitin Rakesh","doi":"10.1016/j.sintl.2024.100312","DOIUrl":"10.1016/j.sintl.2024.100312","url":null,"abstract":"<div><div>This article introduces an analytical model for double-gate AlGaN/GaN MOS-HEMT biosensors to accurately detect pH analytes and charged biomolecules. The device incorporates nanocavities and operates on the concept of dielectric modulation, presuming the presence of a native oxide layer on the surface of the AlGaN layer. The pH of the analyte is represented as the interface charge. Numerical simulations evaluate the biosensor's effectiveness by analyzing its sensitivity to drain ON current (S<sub>I</sub>) and threshold voltage (S<sub>V</sub>). The device exhibited a peak S<sub>V</sub> of 586.5 mV, a value tenfold more significant than the Nernst limit for pH analyte. The maximum S<sub>I</sub>, computed at the peak transconductance, was determined to be 135.5 mA/mm/pH at V<sub>G</sub> = −2V and V<sub>D</sub> = 5V. The biosensor response to a charged biomolecule is assessed by considering the dielectric constant and charge density (ρ). The biosensor exhibited a maximum S<sub>I</sub> of 0.225 at V<sub>D</sub> = 5V and V<sub>G</sub> = −1V and S<sub>V</sub> of 1.488V for charged biomolecule at ρ = 1 × 10<sup>12</sup>/cm<sup>2</sup>. The impact of the bias voltages, ion molar concentration of pH analyte, AlGaN layer thickness and cavity length on the S<sub>I</sub> of the device is explored in detail. The S<sub>I</sub> for pH analytes is unaffected by the AlGaN layer thickness but enhanced with ion molar concentration and cavity length. However, for charged biomolecules, S<sub>I</sub> decreased with increased AlGaN layer thickness and improved with cavity length.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100312"},"PeriodicalIF":0.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142723833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication of a non-enzymatic photoelectrochemical sensor based on a BiOBr-CuO nanocomposite for detecting Glucose and Tetracycline 基于 BiOBr-CuO 纳米复合材料制作用于检测葡萄糖和四环素的非酶光电化学传感器

Sensors International Pub Date : 2024-11-21 DOI: 10.1016/j.sintl.2024.100310

AnnieCanisius D , Joselene Suzan Jennifer P , Joe Raja Ruban M , Davis Varghese , Gladys Joysi M , Muthupandi S , Madhavan J , Victor Antony Raj M , Saravanan Muthupandian

{"title":"Fabrication of a non-enzymatic photoelectrochemical sensor based on a BiOBr-CuO nanocomposite for detecting Glucose and Tetracycline","authors":"AnnieCanisius D , Joselene Suzan Jennifer P , Joe Raja Ruban M , Davis Varghese , Gladys Joysi M , Muthupandi S , Madhavan J , Victor Antony Raj M , Saravanan Muthupandian","doi":"10.1016/j.sintl.2024.100310","DOIUrl":"10.1016/j.sintl.2024.100310","url":null,"abstract":"<div><div>In this study, we developed a non-enzymatic photoelectrochemical sensor using a BiOBr-CuO (BiCu) electrode, which was synthesized via solvothermal method. The sensor was designed for the simultaneous detection of glucose and tetracycline. Our study revealed that the BiCu electrode exhibited superior photocurrent generation compared to the individual BiOBr and CuO electrodes, as demonstrated by cyclic voltammetry and amperometric studies. The BiCu electrode's performance has increased due to the formation of a heterojunction between CuO and BiOBr, which modifies the UV–visible DRS spectrum and generates an internal electric field that reduces the recombination of the photogenerated carriers. This enhanced the capability of the sensor to detect both glucose and tetracycline. We successfully applied the proposed photoelectrochemical sensor to detect human blood glucose level. The sensitivity and detection limit for glucose and tetracycline are 0.1342 mAmM<sup>−1</sup>cm<sup>−2</sup>, 0.014 mM and 1.7234 mAmM<sup>−1</sup>cm<sup>−2</sup>, 2.0 μM respectively. Thus, the fabricated electrode demonstrated exceptional catalytic activity, high selectivity, good reproducibility, wide linear detection range, low limit of detection,long-term stability, ease of synthesis, good stability and notable selectivity for detecting both glucose and tetracycline This suggests that the BiCu electrode has significant potential as a reliable platform for the detection of glucose and tetracycline.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100310"},"PeriodicalIF":0.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142704508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A portable easy-to-use triboelectric sensor for arteriovenous fistula monitoring in dialysis patients 用于监测透析患者动静脉瘘的便携式易用三电导传感器

Sensors International Pub Date : 2024-11-13 DOI: 10.1016/j.sintl.2024.100309

Salvatore A. Pullano , Giuseppe Oliva , Pierangela Presta , Nazareno Carullo , Michela Musolino , Michele Andreucci , Davide Bolignano , Antonino S. Fiorillo , Giuseppe Coppolino

{"title":"A portable easy-to-use triboelectric sensor for arteriovenous fistula monitoring in dialysis patients","authors":"Salvatore A. Pullano , Giuseppe Oliva , Pierangela Presta , Nazareno Carullo , Michela Musolino , Michele Andreucci , Davide Bolignano , Antonino S. Fiorillo , Giuseppe Coppolino","doi":"10.1016/j.sintl.2024.100309","DOIUrl":"10.1016/j.sintl.2024.100309","url":null,"abstract":"<div><div>Hemodialysis is the primary treatment for patients with total loss of renal function and is performed through a vascular access called an arteriovenous fistula (AVF). AVF can be associated with several complications, such as stenosis, thrombosis, and aneurysms. While digital subtraction angiography (DSA) is the gold standard for AVF monitoring, its limited availability, invasiveness, and harmfulness has enabled Doppler ultrasound (DUS) as alternative technique. Herein, the development of a portable device based on a triboelectric sensor for AVF monitoring that exploits the concept of impedance cardiography (ICG) is presented. The triboelectric sensor consists of a thin polyvinylidene fluoride (PVDF) layer placed close to the AVF to evaluate the triboelectric ICG signal (T-ICG), thus avoiding the need for standard multiple-electrode equipment. Electrocardiographic (ECG) dry electrodes based on a composite of polydimethylsiloxane (PDMS) and multi-walled carbon nanotubes (MWCNTs) were fabricated. Concept validation was performed in a cohort of hemodialysis patients with and without AVF stenosis. The results demonstrated a linear dependence between blood flow and the maximum deviation (dZ/dt<sub>max</sub>) of the T-ICG pattern. Patients with stenosis showed a statistically significant change in morphology at the B-point. The extent of stenosis was evaluated by analyzing the temporal slope of the ICG pattern in the B- and C-point regions, evidencing a linear trend for stenosis from 20 % up to 60 %. The proposed device represents an innovative approach compared with the gold clinical standards for the continuous monitoring of AVF in hemodialysis patients.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100309"},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142653384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photocatalytic and electrochemical sensor detection of ascorbic and uric acid using novel plant extract green synthesis of CaO nanoparticles 利用新型植物提取物绿色合成氧化钙纳米粒子，实现抗坏血酸和尿酸的光催化和电化学传感器检测

Sensors International Pub Date : 2024-11-12 DOI: 10.1016/j.sintl.2024.100308

M.N. Somashekar , M. Dhanalakshmi , T.S. Nagamani , T. Subhas Chandra , T.M. Sharanakumar , C.R. Ravikumar

{"title":"Photocatalytic and electrochemical sensor detection of ascorbic and uric acid using novel plant extract green synthesis of CaO nanoparticles","authors":"M.N. Somashekar , M. Dhanalakshmi , T.S. Nagamani , T. Subhas Chandra , T.M. Sharanakumar , C.R. Ravikumar","doi":"10.1016/j.sintl.2024.100308","DOIUrl":"10.1016/j.sintl.2024.100308","url":null,"abstract":"<div><div>In the present work, a novel fuel made from the leaves of the Gotu kola (Centella Asiatica) plant is used to produce calcium oxide nanoparticles (CaO NPs) in an eco-friendly manner. The results of the PXRD experiments, the average crystallite size for CaO NPs is 38 nm, which is consistent with the findings of the TEM. As per DRS investigation, the energy gap of CaONPs is 3.253 eV. Fast Blue (FB) and Fast Orange (FO) dye photodegradation was effectively enhanced by the plant-mediated CaO NPs under UV-light irradiation, showing high efficiency within 120 min. The CaO demonstrated remarkable photodegradation process against the FO and FB dyes under UV light, with rates of 79.52 % and 61.43 % after 120 min. CaO NPs' electrochemical characteristics were ascertained using a carbon paste electrode (CPE) dipped in a 0.1N HCl solution. In cyclic voltammetry evaluation, the green CaO NPs showed greater sensitivity at various scan rates. Ascorbic acid and uric acid were finally shown to have exceptional redox reaction and ascorbic acid and uric acid detection capabilities when they were used as analytes.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100308"},"PeriodicalIF":0.0,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142704505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-channel infrared OPO lidar optical system for remote sensing of greenhouse gases in the atmosphere: Design and characteristics 用于大气温室气体遥感的双通道红外 OPO 激光雷达光学系统：设计与特点

Sensors International Pub Date : 2024-11-07 DOI: 10.1016/j.sintl.2024.100307

S.A. Sadovnikov, S.V. Yakovlev, N.S. Kravtsova, O.A. Romanovskii, D.A. Tuzhilkin

{"title":"Dual-channel infrared OPO lidar optical system for remote sensing of greenhouse gases in the atmosphere: Design and characteristics","authors":"S.A. Sadovnikov, S.V. Yakovlev, N.S. Kravtsova, O.A. Romanovskii, D.A. Tuzhilkin","doi":"10.1016/j.sintl.2024.100307","DOIUrl":"10.1016/j.sintl.2024.100307","url":null,"abstract":"<div><div>Current global warming and climate change under the greenhouse effect call for a thorough understanding of the spatial distribution of greenhouse gases in different atmospheric layers. Lidar systems are the most effective for remote greenhouse gas monitoring. We design a two-channel infrared OPO lidar optical system for remote DIAL/DOAS sensing of carbon dioxide and water vapor in the atmosphere. In this work, optimal geometric parameters of the transceiving channel of the lidar optical system are chosen, a need to focus laser radiation at a distance of 1 km from an observation point is demonstrated, and numerical simulations confirm the possibility of detecting lidar signals ranging from 10<sup>−7</sup> to 10<sup>−10</sup> W in the informative spectral range 4800–5100 cm<sup>−1</sup> (1960–2083 nm). Laboratory experiments with the main components of the lidar system with experimentally confirmed parameters, which simulate atmospheric measurements of CO<sub>2</sub> absorption at a calibrated sensing wavelength of 2005 nm (4987 cm<sup>−1</sup>) (pressure of 1 atm; CO<sub>2</sub> concentration corresponding to the midlatitude summer background atmosphere) in the informative spectral range of the lidar system, enable selecting a pair of wavelengths with resonant absorption of the target gas near 2005 nm to study the background state of the atmosphere in the surface layer. Efficiency of the lidar optical system is confirmed by in situ test experiments, where backscattering signals from a topographic target with an albedo of ∼0.15 spaced 168 m apart from an observer are recorded at 60 mV when operating along a horizontal atmospheric path. The lidar system we design can be used in measuring complexes at carbon test sites. It can also be used for atmospheric monitoring in industrial centers, at background measuring stations, and in swamp areas.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100307"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142653383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Flange joint monitoring based on strain measurement with fiber optic sensors embedded in gaskets 利用嵌入垫片的光纤传感器进行应变测量，从而实现法兰接头监测

Sensors International Pub Date : 2024-11-04 DOI: 10.1016/j.sintl.2024.100306

Valerii Matveenko, Andrey Fedorov, Grigorii Serovaev, Elizaveta Galkina, Elizaveta Vindokurova

{"title":"Flange joint monitoring based on strain measurement with fiber optic sensors embedded in gaskets","authors":"Valerii Matveenko, Andrey Fedorov, Grigorii Serovaev, Elizaveta Galkina, Elizaveta Vindokurova","doi":"10.1016/j.sintl.2024.100306","DOIUrl":"10.1016/j.sintl.2024.100306","url":null,"abstract":"<div><div>The paper demonstrates the effectiveness of using numerical simulation to select parameters of the system for monitoring the deformation behavior of structures. Consideration is given to a bolted flange connection with a gasket, the performance of which is determined by the level of bolt tightening. Bolt tension control technique is based on the strain measurement with fiber optic sensors embedded in the gasket. The results of numerical modeling of deformation for different variants of bolt tensioning are discussed. Strain measurement in the gasket by means of distributed fiber-optic sensors on the basis of Rayleigh scattering is carried out taking into account the results of numerical simulation. Another type of fiber optic sensors that is based on the Bragg gratings is used to implement additional control of the results of measurement. An algorithm to realize strain measurement by two types of sensors located on the same optic fiber is proposed. The results of experimental strain measurements demonstrate that fiber optic sensors can be used to detect changes in bolt tensioning, which can cause failure of a flange joint.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100306"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142653385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Near-field metasurface sensor for an early-stage breast cancer detection 用于早期乳腺癌检测的近场元表面传感器

Sensors International Pub Date : 2024-10-23 DOI: 10.1016/j.sintl.2024.100305

Maged A. Aldhaeebi , Thamer Almoneef , Saeed Bamatraf , A.O. Aldhaibain , Osamah Bakhalah , Saleh Alhdad , Sumaia Bakhalah , M. Kamran Saleem

{"title":"Near-field metasurface sensor for an early-stage breast cancer detection","authors":"Maged A. Aldhaeebi , Thamer Almoneef , Saeed Bamatraf , A.O. Aldhaibain , Osamah Bakhalah , Saleh Alhdad , Sumaia Bakhalah , M. Kamran Saleem","doi":"10.1016/j.sintl.2024.100305","DOIUrl":"10.1016/j.sintl.2024.100305","url":null,"abstract":"<div><div>In this paper, a novel and highly sensitive metasurface sensor for microwave breast tumor detection is proposed. The proposed sensor array comprises 8 × 8 small-size sensor elements that are capable of reacting to changes in both electric and magnetic fields. This allows the sensor to detect even minor variations in the surrounding medium, resulting in improved sensitivity. Additionally, designing a sensor array improves sensitivity by covering all areas of the breast tissues with multiple small sensor elements. Numerical studies have been conducted to assess the sensor sensitivity using realistic healthy and non-healthy breast models with diagnosed tumors placed at different locations within healthy breast models in the CST simulation environment at varying stand-off distances. An experiment was conducted to validate the sensor’s concept. It involved testing a metasurface sensor with phantoms resembling both healthy female breast tissues and those with a 10 mm tumor. The results from simulations and experiments demonstrate that the metasurface sensor is capable of detecting breast tumors at different distances. For safety compliance, specific absorption rate (SAR) values were obtained through both simulation and experimentation. The simulated SAR values were calculated to be 0.357 W/kg and 0.216 W/kg at 1 g and 10 g, respectively, using 17 dBm for safety. The measured SAR values were 0.101 W/kg and 0.1 W/kg at 1 g and 10 g, respectively.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100305"},"PeriodicalIF":0.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142555037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular engineering of a fluorescent probe for highly efficient detection of human serum albumin in biological fluid 用于高效检测生物液体中人血清白蛋白的荧光探针的分子工程学研究

Sensors International Pub Date : 2024-10-15 DOI: 10.1016/j.sintl.2024.100304

Raja Chinnappan , Tanveer Ahmad Mir , Shanmugam Easwaramoorthi , Gopika Sunil , Ancy Feba , Balamurugan Kanagasabai , Shadil Ibrahim Wani , Maram N. Sandouka , Alaa Alzhrani , Sandhanasamy Devanesan , Mohamad S. AlSalhi , Naresh Kumar Mani , Wael Al-Kattan , Ahmed Yaqinuddin , Abdullah M. Assiri , Dieter C. Broering

{"title":"Molecular engineering of a fluorescent probe for highly efficient detection of human serum albumin in biological fluid","authors":"Raja Chinnappan , Tanveer Ahmad Mir , Shanmugam Easwaramoorthi , Gopika Sunil , Ancy Feba , Balamurugan Kanagasabai , Shadil Ibrahim Wani , Maram N. Sandouka , Alaa Alzhrani , Sandhanasamy Devanesan , Mohamad S. AlSalhi , Naresh Kumar Mani , Wael Al-Kattan , Ahmed Yaqinuddin , Abdullah M. Assiri , Dieter C. Broering","doi":"10.1016/j.sintl.2024.100304","DOIUrl":"10.1016/j.sintl.2024.100304","url":null,"abstract":"<div><div>Human serum albumin (HSA) is synthesized by the liver, accounting for 60 % of total plasma protein in vertebrates' blood. It is the most predominant extracellular plasma protein that acts as a repository and transporter of exogenous and endogenous substances in the blood of healthy humans. Decreased albumin concentration in the human body or its abnormal levels indicate the occurrence of hepatic, renal, and digestive-related diseases. Therefore, accurate quantification of HSA is of great significance in diagnostic testing and routine clinical analysis of albumin-linked diseases. Herein, a class of triphenylamine rhodanine-3-acetic acid (mRA)-a bifunctional fluorescent molecule with twisted intramolecular charge transfer (TICT)-induced emission characteristics is synthesized and employed as a novel sensing probe for the fluorescent detection of human albumin. mRA can be selectively lighted up through site-specific interactions with serum albumin-binding moieties and show enhanced photophysical or biological response efficacy. Understanding the interaction of mRA with HSA at the molecular level was carried out using docking methodology to explore the site-specific interaction phenomenon. The resulting fluorescence strategy produced a dose-dependent signal response enhancement upon interaction with HSA in the concentration range of 0.01–400 μg/ml. The sensor probe exhibits a low detection limit of 10 ng/mL and is found to be a feasible, low-cost, and effective approach for HSA analysis in complex biological fluids for early detection and diagnosis of albumin-related diseases.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100304"},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Privacy-concerned averaged human activeness monitoring and normal pattern recognizing with single passive infrared sensor using one-dimensional modeling 利用单个被动红外传感器，通过一维建模实现对人类活动性的平均监测和正常模式识别，兼顾隐私问题

Sensors International Pub Date : 2024-09-28 DOI: 10.1016/j.sintl.2024.100303

Tajim Md. Niamat Ullah Akhund, Kenbu Teramoto

{"title":"Privacy-concerned averaged human activeness monitoring and normal pattern recognizing with single passive infrared sensor using one-dimensional modeling","authors":"Tajim Md. Niamat Ullah Akhund, Kenbu Teramoto","doi":"10.1016/j.sintl.2024.100303","DOIUrl":"10.1016/j.sintl.2024.100303","url":null,"abstract":"<div><div>Detecting human activity through cameras and machine learning methods raises significant privacy concerns, while alternatives like thermal cameras can be expensive. Passive infrared (PIR) sensors present a cost-effective and privacy-preserving solution, commonly used in home settings for motion detection. This study introduces a system for monitoring human activeness using a single PIR sensor, focusing on privacy preservation. The proposed one-dimensional model, based on the Laplace distribution, emphasizes the role of the parameter <span><math><mi>μ</mi></math></span> in defining velocity distributions. Through real-world experiments with a Raspberry Pi and PIR sensor, the effectiveness of the model in capturing human activeness is validated. The study investigates how different <span><math><mi>μ</mi></math></span> values correlate with activity levels and detect abnormalities. Additionally, the paper addresses the stochastic nature of human behavior, and the impact of <span><math><mi>μ</mi></math></span> on predictability and variability, and provides insights into detection thresholds and interval times. The findings highlight the potential for enhancing abnormality detection and suggest a comprehensive understanding of human activeness.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100303"},"PeriodicalIF":0.0,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142427576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A method to detect enzymatic reactions with field effect transistor 利用场效应晶体管检测酶反应的方法

Sensors International Pub Date : 2024-09-19 DOI: 10.1016/j.sintl.2024.100302

Alexander Kuznetsov , Mariia Andrianova , Dmitriy Ryazantsev , Andrey Sheshil , Vitaliy Grudtsov , Valerii Vechorko , Natalia Komarova

{"title":"A method to detect enzymatic reactions with field effect transistor","authors":"Alexander Kuznetsov , Mariia Andrianova , Dmitriy Ryazantsev , Andrey Sheshil , Vitaliy Grudtsov , Valerii Vechorko , Natalia Komarova","doi":"10.1016/j.sintl.2024.100302","DOIUrl":"10.1016/j.sintl.2024.100302","url":null,"abstract":"<div><div>Study of enzyme-substrate interactions is a task of great practical and scientific importance. This paper describes the application of ion-sensitive field effect transistors in quasi-equilibrium state for examination of enzymatic reactions. A reaction occurring in the liquid gate affects the chemical potential of electrons in this gate, and this phenomenon may be used to explore biochemical interactions. This strategy can be applied to detect interactions of enzymes with substrates, inhibitors and activators regardless of their optical and electrochemical properties. Using the developed method, the reactions catalyzed by the enzymes belonging to six different EC classes were analyzed, and Michaelis constants for their substrates were determibed. <em>K</em><sub><em>m</em></sub> values obtained using the proposed method were in good agreement with those obtained with standard colorimetric and fluorimentric assays. Practical potential of the described method was demonstrated by studying the interactions of a diagnostically significant enzyme α-D-galactosidase with its natural and artificial substrates and its inhibitor. <em>K</em><sub><em>m</em></sub> values for α-D-galactosidase using melibiose and raffinose as substrates and IC50 value for the enzyme inhibitor 1-deoxygalactonojirimycin were determined. The described method allows rapid and label-free investigation of enzyme interactions with substrates, inhibitors and activators for a wide range of biocatalysts.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100302"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266635112400024X/pdfft?md5=4d52ee86a1d882d955efddee7d99e5d4&pid=1-s2.0-S266635112400024X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142312781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0