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Earthquakes in the blind spot 盲区的地震
IF 45.8 1区 综合性期刊
Science Pub Date : 2025-09-25 DOI: 10.1126/science.aeb1414
Emily E. Brodsky, Sergio Ruiz
{"title":"Earthquakes in the blind spot","authors":"Emily E. Brodsky,&nbsp;Sergio Ruiz","doi":"10.1126/science.aeb1414","DOIUrl":"10.1126/science.aeb1414","url":null,"abstract":"<div >Despite major advances in understanding where and why earthquakes happen, the world’s most energetic events continue to occur without warning. For example, the 2025 Kamchatka earthquake off the far-Eastern coast of Russia triggered tsunami warnings across the Pacific and the evacuation of millions of people. It is among the 10 strongest earthquakes since 1900 and the largest worldwide since 2011. Could such a megathrust event have been predicted? The answer is “maybe,” had there been sufficient instrumentation at the right time and place on the ocean floor. On page 1361 of this issue, Atterholt <i>et al.</i> (<i>1</i>) report a new strategy to improve seismic sensing in the ocean by transforming a fiber-optic array into seismometers that detect the ground motion associated with seismic waves generated by earthquakes. This approach could help identify large earthquakes on a time scale of seconds and mitigate the impact on public safety.</div>","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6767","pages":""},"PeriodicalIF":45.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145135896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gardening strategies of termite farmers 白蚁农民的园艺策略
IF 45.8 1区 综合性期刊
Science Pub Date : 2025-09-25 DOI: 10.1126/science.aeb5715
Aryel C. Goes, Rachelle M. M. Adams
{"title":"Gardening strategies of termite farmers","authors":"Aryel C. Goes,&nbsp;Rachelle M. M. Adams","doi":"10.1126/science.aeb5715","DOIUrl":"10.1126/science.aeb5715","url":null,"abstract":"<div >Long before humans began cultivating wheat or corn, social insects (i.e., ants and termites) had already developed agricultural practices (<i>1</i>, <i>2</i>). For example, the termite <i>Odontotermes obesus</i> evolved a symbiotic relationship with the fungi <i>Termitomyces</i>, which serves as its food source. In return, the termites build a nest that protects the fungal comb, or “garden.” These insects are therefore driven to increase the yield of their garden by exhibiting behaviors such as garden feeding, habitual planting, altering the garden environment, and harvesting (<i>1</i>). Just as humans protect gardens and crops from pests, fungus-farming insects likewise have pest management strategies. On page 1366, Panchal <i>et al</i>. (<i>3</i>) report how fungus-farming <i>O. obesus</i> leverages fungicide-releasing microbes to suppress the pathogenic fungi <i>Pseudoxylaria</i>. The finding points to the convergence of gardening practices among distantly related organisms and reveals an expansion of the <i>O. obesus</i> symbiotic species network to include fungistatic microbes (<i>2</i>, <i>4</i>).</div>","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6767","pages":""},"PeriodicalIF":45.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145135898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Science Journals 在科学期刊上
IF 45.8 1区 综合性期刊
Science Pub Date : 2025-09-25 DOI: 10.1126/science.aec5108
Yury Suleymanov, Angela Hessler, Annalisa M. VanHook, Ian S. Osborne, Di Jiang, Simon White, Sacha Vignieri, Sarah A. Lemprière, Yevgeniya Nusinovich, Jesse Smith, Michael A. Funk, L. Bryan Ray, Bianca Lopez, Courtney Malo, Claire Olingy
{"title":"In Science Journals","authors":"Yury Suleymanov,&nbsp;Angela Hessler,&nbsp;Annalisa M. VanHook,&nbsp;Ian S. Osborne,&nbsp;Di Jiang,&nbsp;Simon White,&nbsp;Sacha Vignieri,&nbsp;Sarah A. Lemprière,&nbsp;Yevgeniya Nusinovich,&nbsp;Jesse Smith,&nbsp;Michael A. Funk,&nbsp;L. Bryan Ray,&nbsp;Bianca Lopez,&nbsp;Courtney Malo,&nbsp;Claire Olingy","doi":"10.1126/science.aec5108","DOIUrl":"10.1126/science.aec5108","url":null,"abstract":"","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6767","pages":""},"PeriodicalIF":45.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/science.aec5108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145135857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The EPA’s shaken foundation 环保局的根基动摇了
IF 45.8 1区 综合性期刊
Science Pub Date : 2025-09-25 DOI: 10.1126/science.aec2623
H. Christopher Frey
{"title":"The EPA’s shaken foundation","authors":"H. Christopher Frey","doi":"10.1126/science.aec2623","DOIUrl":"10.1126/science.aec2623","url":null,"abstract":"","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6767","pages":""},"PeriodicalIF":45.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/science.aec2623","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145135890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fungus-farming termites can protect their crop by confining weeds with fungistatic soil boluses 种植真菌的白蚁可以用防真菌土丸来限制杂草，从而保护他们的作物
IF 45.8 1区 综合性期刊
Science Pub Date : 2025-09-25 DOI: 10.1126/science.adr2713
Aanchal Panchal, Ruchira Sen, Renuka Agarwal, Anjali Rana, Rhitoban Raychoudhury
{"title":"Fungus-farming termites can protect their crop by confining weeds with fungistatic soil boluses","authors":"Aanchal Panchal,&nbsp;Ruchira Sen,&nbsp;Renuka Agarwal,&nbsp;Anjali Rana,&nbsp;Rhitoban Raychoudhury","doi":"10.1126/science.adr2713","DOIUrl":"10.1126/science.adr2713","url":null,"abstract":"<div >The symbiotic agriculture of fungus-farming termites can collapse if they fail to prevent invading weeds. Previous studies suggest a role for symbiotic fungistatic microbes in bringing about weed control. However, how termites employ these microbes to suppress fungal weeds without affecting the fungal cultivar remains unknown. We show that the fungus-farming termite <i>Odontotermes obesus</i> uses specific behaviors to remove, isolate, and suppress the growth of the fungal weed <i>Pseudoxylaria</i>, primarily by encasing it with soil boluses containing fungistatic microbes. These behaviors efficiently suppress the weed without affecting the crop. This integration of specific behaviors with termite-derived microbes appears to be the proximate mechanism of how microbes are topically used by termites to confine the weed while keeping the crop unaffected.</div>","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6767","pages":""},"PeriodicalIF":45.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145135897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What to Expect When You''re Dead: An Ancient Tour of Death and the Afterlife 当你死后会发生什么：死亡和来世的古老之旅
IF 45.8 1区 综合性期刊
Science Pub Date : 2025-09-25 DOI: 10.1126/science.aeb7564
{"title":"What to Expect When You''re Dead: An Ancient Tour of Death and the Afterlife","authors":"","doi":"10.1126/science.aeb7564","DOIUrl":"10.1126/science.aeb7564","url":null,"abstract":"","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6767","pages":""},"PeriodicalIF":45.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/science.aeb7564","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145135887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hope, rediscovered. 希望,重新发现。
IF 45.8 1区 综合性期刊
Science Pub Date : 2025-09-25 DOI: 10.1126/science.aec4467
Easton R White
{"title":"Hope, rediscovered.","authors":"Easton R White","doi":"10.1126/science.aec4467","DOIUrl":"https://doi.org/10.1126/science.aec4467","url":null,"abstract":"","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6767","pages":"1374"},"PeriodicalIF":45.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding avian influenza mortality 了解禽流感死亡率
IF 45.8 1区 综合性期刊
Science Pub Date : 2025-09-25 DOI: 10.1126/science.adx7159
John M. Drake
{"title":"Understanding avian influenza mortality","authors":"John M. Drake","doi":"10.1126/science.adx7159","DOIUrl":"10.1126/science.adx7159","url":null,"abstract":"","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6767","pages":""},"PeriodicalIF":45.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/science.adx7159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145135889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The cosmic time machine on Long Island winds down. 长岛上的宇宙时光机停止运转。
IF 56.9 1区 综合性期刊
Science Pub Date : 2025-09-25 DOI: 10.1126/science.aec5469
Adrian Cho
{"title":"The cosmic time machine on Long Island winds down.","authors":"Adrian Cho","doi":"10.1126/science.aec5469","DOIUrl":"https://doi.org/10.1126/science.aec5469","url":null,"abstract":"The Relativistic Heavy Ion Collider re-created the Big Bang. The torch now passes to Europe.","PeriodicalId":21678,"journal":{"name":"Science","volume":"16 1","pages":"1284-1285"},"PeriodicalIF":56.9,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145140462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Megabase-scale human genome rearrangement with programmable bridge recombinases 用可编程桥式重组酶进行百万级人类基因组重排
IF 56.9 1区 综合性期刊
Science Pub Date : 2025-09-25 DOI: 10.1126/science.adz0276
Nicholas T. Perry, Liam J. Bartie, Dhruva Katrekar, Gabriel A. Gonzalez, Matthew G. Durrant, James J. Pai, Alison Fanton, Juliana Q. Martins, Masahiro Hiraizumi, Chiara Ricci-Tam, Hiroshi Nishimasu, Silvana Konermann, Patrick D. Hsu
{"title":"Megabase-scale human genome rearrangement with programmable bridge recombinases","authors":"Nicholas T. Perry, Liam J. Bartie, Dhruva Katrekar, Gabriel A. Gonzalez, Matthew G. Durrant, James J. Pai, Alison Fanton, Juliana Q. Martins, Masahiro Hiraizumi, Chiara Ricci-Tam, Hiroshi Nishimasu, Silvana Konermann, Patrick D. Hsu","doi":"10.1126/science.adz0276","DOIUrl":"https://doi.org/10.1126/science.adz0276","url":null,"abstract":"Bridge recombinases are naturally occurring RNA-guided DNA recombinases that we previously demonstrated can programmably insert, excise, and invert DNA in vitro and in <jats:italic toggle=\"yes\">Escherichia coli</jats:italic> . In this study, we report the discovery and engineering of the bridge recombinase ortholog ISCro4 for universal rearrangements of the human genome. We defined strategies for the optimal application of bridge systems, leveraging mechanistic insights to improve their targeting specificity. Through rational engineering of the ISCro4 bridge RNA and deep mutational scanning of its recombinase, we achieved up to 20% insertion efficiency into the human genome and genome-wide specificity as high as 82%. We further demonstrated intrachromosomal inversion and excision, mobilizing up to 0.93 megabases of DNA. Lastly, we provided proof-of-concept for plasmid-based excision of disease-relevant gene regulatory regions or repeat expansions.","PeriodicalId":21678,"journal":{"name":"Science","volume":"18 1","pages":""},"PeriodicalIF":56.9,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145134486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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