New Phytologist最新文献

{"title":"Metabolic modeling identifies determinants of thermal growth responses in Arabidopsis thaliana","authors":"Philipp Wendering, Gregory M. Andreou, Roosa A. E. Laitinen, Zoran Nikoloski","doi":"10.1111/nph.20420","DOIUrl":"https://doi.org/10.1111/nph.20420","url":null,"abstract":"<h2> Introduction</h2>\u0000<p>Global food security depends on crop yields that are severely threatened by more fluctuating and increasing temperatures – a hallmark of future climate scenarios (Wheeler & von Braun, <span>2013</span>). Ambient temperature affects all aspects of the plant life cycle, from development and growth to reproduction (Casal & Balasubramanian, <span>2019</span>; Zhu <i>et al</i>., <span>2022</span>). Plant responses to temperature changes are most immediately observed at the level of metabolism, followed by changes in gene expression to reestablish homeostasis (Casal & Balasubramanian, <span>2019</span>). Considering that metabolism is tightly linked to plant growth (Meyer <i>et al</i>., <span>2007</span>; Pyl <i>et al</i>., <span>2012</span>), metabolic changes can facilitate rapid plant adaptation to temperature changes at a minimal growth penalty. While we understand that metabolic flexibility is achieved by rerouting nutrient flows within the plant metabolic network, we know little about (1) which enzymes limit plant metabolic changes in temperature? And (2) how these limits emerge from temperature-dependent biochemical constraints under which the metabolic network operates? The availability of a mathematical model that can accurately predict genetic and molecular determinants that affect plant temperature responses will address both questions.</p>\u0000<p>A few metabolic models have already considered the effect of temperature on processes that directly affect plant growth (Clark <i>et al</i>., <span>2020</span>; Wendering & Nikoloski, <span>2023</span>). For instance, the classical mathematical model of C<sub>3</sub> photosynthesis (Farquhar <i>et al</i>., <span>1980</span>) – an indispensable metabolic pathway for photoautotrophic growth – has been extended to predict effects of temperature changes in net CO<sub>2</sub> assimilation (Scafaro <i>et al</i>., <span>2023</span>). However, this and other modeling efforts addressing responses of metabolic pathways to temperature change (Kannan <i>et al</i>., <span>2019</span>; Herrmann <i>et al</i>., <span>2020</span>; Inoue & Noguchi, <span>2021</span>) consider only a few, lumped metabolic reactions. As a result, these models cannot be used to identify all gene targets modulating plant thermal responses, thus restricting their capacity to predict mitigation strategies. In addition, they cannot be used to make predictions about plant growth responses, due to the limited focus on one selected metabolic pathway. By contrast, genome-scale metabolic models, representing the entirety of known metabolic reactions in a system, have been successfully used to predict growth-related phenotypes and genetic engineering strategies for their modulation using approaches from the constraint-based modeling framework (Herrmann <i>et al</i>., <span>2019</span>; Tong <i>et al</i>., <span>2023</span>; Wendering & Nikoloski, <span>2023</span>). These models allow the design of r","PeriodicalId":214,"journal":{"name":"New Phytologist","volume":"13 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glycoside-specific metabolomics reveals the novel mechanism of glycinebetaine-induced cold tolerance by regulating apigenin glycosylation in tea plants","authors":"Shan Huang, Sasa Zhang, Xuejing Ma, Xin Zheng, Yaojia Liu, Qinghua Zhu, Xiaoqin Luo, Jilai Cui, Chuankui Song","doi":"10.1111/nph.20410","DOIUrl":"https://doi.org/10.1111/nph.20410","url":null,"abstract":"<p>\u0000</p><ul>\u0000<li>Glycosylation is a key modification that affects secondary metabolites under stress and is influenced by glycinebetaine (GB) to regulate plant stress tolerance. However, the complexity and detection challenges of glycosides hinder our understanding of the regulatory mechanisms of their metabolic interaction with GB during stress.</li>\u0000<li>A glycoside-specific metabolomic approach utilizing cone voltage-induced in-source dissociation was developed, achieving precise and high-throughput detection of glycosides in tea plants by narrowing the target ion range by 94.3%. Combined with enzyme activity assays, exogenous spraying, and gene silencing, this approach helps investigate the role of GB-glycosides cascade effect in enhancing cold tolerance of tea plants.</li>\u0000<li>Our method demonstrated that silencing betaine aldehyde dehydrogenase (<i>CsBADH1</i>) in tea plants altered 60 glycoside ions while reducing GB content and cold tolerance, indicating that glycosylation affects GB-mediated cold tolerance. By combining glycoside-specific with conventional metabolomics, isorhoifolin, a GB-regulated cold response metabolite was discovered, and its precursor apigenin was found to be a new cold tolerance metabolite that enhanced cold tolerance by scavenging reactive oxygen species.</li>\u0000<li>This study reveals a new mechanism by which GB mediated cold tolerance in tea plants through regulating apigenin glycosylation, broadening our understanding of the role of glycosylation in plant cold tolerance.</li>\u0000</ul><p></p>","PeriodicalId":214,"journal":{"name":"New Phytologist","volume":"19 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proximal remote sensing: an essential tool for bridging the gap between high-resolution ecosystem monitoring and global ecology","authors":"Zoe Amie Pierrat, Troy S. Magney, Will P. Richardson, Benjamin R. K. Runkle, Jen L. Diehl, Xi Yang, William Woodgate, William K. Smith, Miriam R. Johnston, Yohanes R. S. Ginting, Gerbrand Koren, Loren P. Albert, Christopher L. Kibler, Bryn E. Morgan, Mallory Barnes, Adriana Uscanga, Charles Devine, Mostafa Javadian, Karem Meza, Tommaso Julitta, Giulia Tagliabue, Matthew P. Dannenberg, Michal Antala, Christopher Y. S. Wong, Andre L. D. Santos, Koen Hufkens, Julia K. Marrs, Atticus E. L. Stovall, Yujie Liu, Joshua B. Fisher, John A. Gamon, Kerry Cawse-Nicholson","doi":"10.1111/nph.20405","DOIUrl":"https://doi.org/10.1111/nph.20405","url":null,"abstract":"A new proliferation of optical instruments that can be attached to towers over or within ecosystems, or ‘proximal’ remote sensing, enables a comprehensive characterization of terrestrial ecosystem structure, function, and fluxes of energy, water, and carbon. Proximal remote sensing can bridge the gap between individual plants, site-level eddy-covariance fluxes, and airborne and spaceborne remote sensing by providing continuous data at a high-spatiotemporal resolution. Here, we review recent advances in proximal remote sensing for improving our mechanistic understanding of plant and ecosystem processes, model development, and validation of current and upcoming satellite missions. We provide current best practices for data availability and metadata for proximal remote sensing: spectral reflectance, solar-induced fluorescence, thermal infrared radiation, microwave backscatter, and LiDAR. Our paper outlines the steps necessary for making these data streams more widespread, accessible, interoperable, and information-rich, enabling us to address key ecological questions unanswerable from space-based observations alone and, ultimately, to demonstrate the feasibility of these technologies to address critical questions in local and global ecology.","PeriodicalId":214,"journal":{"name":"New Phytologist","volume":"6 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143020977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stress resilience in plants: the complex interplay between heat stress memory and resetting","authors":"Tobias Staacke, Bernd Mueller-Roeber, Salma Balazadeh","doi":"10.1111/nph.20377","DOIUrl":"https://doi.org/10.1111/nph.20377","url":null,"abstract":"Heat stress (HS) poses a major challenge to plants and agriculture, especially during climate change-induced heatwaves. Plants have evolved mechanisms to combat HS and remember past stress. This memory involves lasting changes in specific stress responses, enabling plants to better anticipate and react to future heat events. HS memory is a multi-layered cellular phenomenon that, in addition to epigenetic modifications, involves changes in protein quality control, metabolic pathways and broader physiological adjustments. An essential aspect of modulating stress memory is timely resetting, which restores defense responses to baseline levels and optimizes resource allocation for growth. Balancing stress memory with resetting enables plants to withstand stress while maintaining growth and reproductive capacity. In this review, we discuss mechanisms and regulatory layers of HS memory and resetting, highlighting their critical balance for enhancing stress resilience and plant fitness. We primarily focus on the model plant <i>Arabidopsis thaliana</i> due to the limited research on other species and outline key areas for future study.","PeriodicalId":214,"journal":{"name":"New Phytologist","volume":"4 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stand density and local climate drive allocation of GPP to aboveground woody biomass","authors":"Steven A. Kannenberg, Flurin Babst, Mallory L. Barnes, Antoine Cabon, Matthew P. Dannenberg, Miriam R. Johnston, William R. L. Anderegg","doi":"10.1111/nph.20414","DOIUrl":"https://doi.org/10.1111/nph.20414","url":null,"abstract":"<p>\u0000</p><ul>\u0000<li>The partitioning of photosynthate among various forest carbon pools is a key process regulating long-term carbon sequestration, with allocation to aboveground woody biomass carbon (AGBC) in particular playing an outsized role in the global carbon cycle due to its slow residence time. However, directly estimating the fraction of gross primary productivity (GPP) that goes to AGBC has historically been difficult and time-consuming, leaving us with persistent uncertainties.</li>\u0000<li>We used an extensive dataset of tree-ring chronologies co-located at flux towers to assess the coupling between AGBC and GPP, calculate the fraction of fixed carbon that is allocated to AGBC, and understand the drivers of variability in this fraction.</li>\u0000<li>We found that annual AGBC and GPP were rarely correlated, and that annual AGBC represented only a small fraction (<i>c</i>. 9%) of fixed carbon. This fraction varied considerably across sites and was driven by differences in stand density and site climate. Annual AGBC was suppressed by <i>c</i>. 30% during drought and remained below average for years afterward.</li>\u0000<li>These results imply that assumptions of relatively stationary allocation of GPP to woody biomass and other plant tissues could lead to systematic biases in modeled carbon accumulation in different plant pools and thus in carbon residence time.</li>\u0000</ul><p></p>","PeriodicalId":214,"journal":{"name":"New Phytologist","volume":"15 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pollination efficiency and the evolution of sex allocation – diminishing returns matter","authors":"Lawrence D. Harder, Steven D. Johnson","doi":"10.1111/nph.20389","DOIUrl":"https://doi.org/10.1111/nph.20389","url":null,"abstract":"Immobility of flowering plants requires them to engage pollen vectors to outcross, introducing considerable inefficiency in the conversion of pollen production into sired seeds. Whether inefficiencies influence the evolution of the relative resource allocation to female and male functions has been debated for more than 40 years. Whereas early models suggested no effect, negative interspecific relations of mean pollen production and pollen : ovule ratios to the proportion of removed pollen that is exported to stigmas (pollen-transfer efficiency) indicate otherwise. Here, we consider theoretically a key condition that determines whether the efficiencies of processes (first derivative of process output with respect to input) affect the evolutionarily stable sex (ESS) allocation. No effect arises if all individuals experience the same efficiency. By contrast, a decline in process efficiency with increasing allocation (diminishing returns) generally reduces the ESS male allocation for a population. Furthermore, differences in the allocation dependence of efficiencies (and hence the ESS sex allocation) among populations/species create a negative relation of realised efficiency to male allocation among species, like that observed empirically. Diminishing returns arise for various processes that affect siring (e.g. pollen export and local pollen competition to fertilise ovules), which may differ in their relative influence on sex allocation among species.","PeriodicalId":214,"journal":{"name":"New Phytologist","volume":"30 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143020978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inorganic nitrogen and organic matter jointly regulate ectomycorrhizal fungi-mediated iron acquisition","authors":"Haihua Wang, Kaile Zhang, Ryan Tappero, Tiffany W. Victor, Jennifer M. Bhatnagar, Rytas Vilgalys, Hui-Ling Liao","doi":"10.1111/nph.20394","DOIUrl":"https://doi.org/10.1111/nph.20394","url":null,"abstract":"<p>\u0000</p><ul>\u0000<li>Ectomycorrhizal fungi (EMF) play a crucial role in facilitating plant nutrient uptake from the soil although inorganic nitrogen (N) can potentially diminish this role. However, the effect of inorganic N availability and organic matter on shaping EMF-mediated plant iron (Fe) uptake remains unclear.</li>\u0000<li>To explore this, we performed a microcosm study on <i>Pinus taeda</i> roots inoculated with <i>Suillus cothurnatus</i> treated with +/−Fe-coated sand, +/−organic matter, and a gradient of NH₄NO₃ concentrations.</li>\u0000<li>Mycorrhiza formation was most favorable under conditions with organic matter, without inorganic N. Synchrotron X-ray microfluorescence imaging on ectomycorrhizal cross-sections suggested that the effect of inorganic N on mycorrhizal Fe acquisition largely depended on organic matter supply. With organic matter, mycorrhizal Fe concentration was significantly decreased as inorganic N levels increased. Conversely, an opposite trend was observed when organic matter was absent. Spatial distribution analysis showed that Fe, zinc, calcium, and copper predominantly accumulated in the fungal mantle across all conditions, highlighting the mantle's critical role in nutrient accumulation and regulation of nutrient transfer to internal compartments.</li>\u0000<li>Our work illustrated that the liberation of soil mineral Fe and the EMF-mediated plant Fe acquisition are jointly regulated by inorganic N and organic matter in the soil.</li>\u0000</ul><p></p>","PeriodicalId":214,"journal":{"name":"New Phytologist","volume":"11 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142991964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transgene-free genome editing in poplar","authors":"Lennart Hoengenaert, Chantal Anders, Jan Van Doorsselaere, Ruben Vanholme, Wout Boerjan","doi":"10.1111/nph.20415","DOIUrl":"https://doi.org/10.1111/nph.20415","url":null,"abstract":"<p>\u0000</p><ul>\u0000<li>Precise gene-editing methods are valuable tools to enhance genetic traits. Gene editing is commonly achieved via stable integration of a gene-editing cassette in the plant's genome. However, this technique is unfavorable for field applications, especially in vegetatively propagated plants, such as many commercial tree species, where the gene-editing cassette cannot be segregated away without breaking the genetic constitution of the elite variety.</li>\u0000<li>Here, we describe an efficient method for generating gene-edited <i>Populus tremula × P. alba</i> (poplar) trees without incorporating foreign DNA into its genome. Using <i>Agrobacterium tumefaciens</i>, we expressed a base-editing construct targeting <i>CCoAOMT1</i> along with the <i>ALS</i> genes for positive selection on a chlorsulfuron-containing medium.</li>\u0000<li>About 50% of the regenerated shoots were derived from transient transformation and were free of T-DNA. Overall, 7% of the chlorsulfuron-resistant shoots were T-DNA free, edited in the <i>CCoAOMT1</i> gene and nonchimeric.</li>\u0000<li>Long-read whole-genome sequencing confirmed the absence of any foreign DNA in the tested gene-edited lines. Additionally, we evaluated the <i>CodA</i> gene as a negative selection marker to eliminate lines that stably incorporated the T-DNA into their genome. Although the latter negative selection is not essential for selecting transgene-free, gene-edited <i>Populus tremula × P. alba</i> shoots, it may prove valuable for other genotypes or varieties.</li>\u0000</ul><p></p>","PeriodicalId":214,"journal":{"name":"New Phytologist","volume":"103 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cell proliferation suppressor RBR1 interacts with ARID1 to promote pollen mitosis via stabilizing DUO1 in Arabidopsis","authors":"Lei Li, Qianqian Hu, Yi Zhao, Ting Jiang, Huaihao Yang, Binglian Zheng","doi":"10.1111/nph.20399","DOIUrl":"https://doi.org/10.1111/nph.20399","url":null,"abstract":"<p>\u0000</p><ul>\u0000<li>In plants, sperm cell formation involves two rounds of pollen mitoses, in which the microspore initiates the first pollen mitosis (PMI) to produce a vegetative cell and a generative cell, then the generative cell continues the second mitosis (PMII) to produce two sperm cells. DUO1, a R2R3 Myb transcription factor, is activated in the generative cell to promote S-G2/M transition during PMII. Loss-of-function of DUO1 caused a complete arrest of PMII. Despite the importance of DUO1, how DUO1 is regulated is largely unexplored.</li>\u0000<li>We previously demonstrated that ARID1, an ARID transcription factor, stimulates <i>DUO1</i> transcription.</li>\u0000<li>Here, we show that cell proliferation suppressor RBR1 interacts with ARID1 to stabilize DUO1. While the C-terminus of RBR1 is dispensable for vegetative growth, it plays a crucial role in reproductive development and facilitates interaction with ARID1. Moreover, DUO1 is a short-lived protein, ARID1 promotes the RBR1–DUO1 interaction, and RBR1 stabilizes DUO1 in a proteasome-dependent manner. Thus, RBR1 promotes DUO1-dependent PMII progression via antagonizing its repressive role in the cell cycle factors CDKA;1 and CYCB1;1.</li>\u0000<li>Collectively, we uncover that ARID1 and RBR1 act in concert to regulate DUO1 at both the transcriptional and posttranscriptional levels, balancing cell specification and cell division.</li>\u0000</ul><p></p>","PeriodicalId":214,"journal":{"name":"New Phytologist","volume":"45 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142991450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apoplastic pH is a chemical switch for extracellular H2O2 signaling in abscisic acid-mediated inhibition of cotyledon greening","authors":"Miao Zhou, Jia Yuan Ye, Yi Ju Shi, Yi Jie Jiang, Yao Zhuang, Qing Yang Zhu, Xing Xing Liu, Zhong Jie Ding, Shao Jian Zheng, Chong Wei Jin","doi":"10.1111/nph.20400","DOIUrl":"https://doi.org/10.1111/nph.20400","url":null,"abstract":"<p>\u0000</p><ul>\u0000<li>The apoplastic pH (pH_Apo) in plants is susceptible to environmental stimuli. However, the biological implications of pH_Apo variation have remained largely unknown.</li>\u0000<li>The universal stress phytohormone abscisic acid (ABA) as well as the major environmental stimuli drought and salinity were selected as representative cases to investigate how changes in pH_Apo relate to plant behaviors in <i>Arabidopsis</i>. Variations in pH_Apo negatively regulated the cotyledon greening inhibition to the universal stress hormone ABA or environmental stimuli through the action of extracellular hydrogen peroxide (eH₂O₂).</li>\u0000<li>Further studies revealed that an increase in pH_Apo diminishes the chemical reactivity of eH₂O₂, effectively functioning as an ‘off’ switch for its action in oxidizing thiols of plasma membrane proteins. Consequently, this suppresses the eH₂O₂-mediated cotyledon greening inhibition to environmental stimuli and ABA, alongside inhibiting the eH₂O₂-mediated intracellular Ca²⁺ signaling. Conversely, a decrease in pH_Apo serves as an ‘on’ switch for the action of eH₂O₂.</li>\u0000<li>In summary, the pH_Apo is a crucial messenger and chemical switch for eH₂O₂ in signal transduction, notwithstanding the apparent simplicity of the underlying mechanism. Our findings provide a novel fundamental biological insight into the significance of pH.</li>\u0000</ul><p></p>","PeriodicalId":214,"journal":{"name":"New Phytologist","volume":"44 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142991451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}