Schizophrenia Research最新文献

{"title":"Risk of microdosing in clinical high-risk populations","authors":"Claire E. Bertrand, Vijay A. Mittal","doi":"10.1016/j.schres.2025.03.017","DOIUrl":"10.1016/j.schres.2025.03.017","url":null,"abstract":"","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"277 ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social and environmental factors during the smoking cessation process: The experiences of adults with serious mental illnesses","authors":"Heather Leutwyler ,&nbsp;Jeremiah Mock ,&nbsp;Erin Hubbard ,&nbsp;Theodore Bussell ,&nbsp;Negin Zahedikia ,&nbsp;Nikta Vaghar ,&nbsp;Dennys Balestra ,&nbsp;Sophia Wuest ,&nbsp;Meg Wallhagen ,&nbsp;Chizimuzo Okoli","doi":"10.1016/j.schres.2025.03.010","DOIUrl":"10.1016/j.schres.2025.03.010","url":null,"abstract":"<div><h3>Introduction</h3><div>People living with schizophrenia and other serious mental illnesses (SMI) face a disproportionate burden of tobacco-related prevalence and, consequently, tobacco-induced morbidity, in comparison to those without SMI. Social and environmental factors play an important role in the health of people with SMI yet less is known about the role of these factors in smoking cessation interventions for adults with SMI. The purpose of this paper is to analyze the social and environmental factors that contributed to the smoking cessation process among adults with SMI enrolled in a smoking cessation program.</div></div><div><h3>Methods</h3><div>We conducted semi-structured qualitative interviews with 30 adults (mean age 47.0, sd 12.2) living with SMI, upon completion of a 12-week smoking cessation program. Grounded Theory methodology guided data collection and analysis.</div></div><div><h3>Results</h3><div>Participants described what contributed to their success with smoking cessation or reduction and elucidated how <em>social and environmental factors</em> played a role in the process. Two broad categories of the social determinants of smoking cessation evolved from the data: 1) support and belonging; and 2) environment, including both the physical and broader sociopolitical.</div></div><div><h3>Discussion/conclusion</h3><div>Our findings illustrate the importance of including social and environmental contexts in health interventions and serve as a reminder to consider social determinants of health when tailoring interventions to meet the unique needs of people living with SMI. These findings can inform the development of tobacco cessation programs in mental health programs, such as the need to incorporate group-based social support, nature-friendly environments, and social activities in the process of cessation.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"277 ","pages":"Pages 111-116"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143562672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with clinically relevant weight loss in men and women with psychotic disorders","authors":"P. Di Prinzio,&nbsp;Vera A. Morgan,&nbsp;A. Waterreus","doi":"10.1016/j.schres.2025.03.007","DOIUrl":"10.1016/j.schres.2025.03.007","url":null,"abstract":"<div><div>Weight gain presents a substantial problem for people with psychotic disorders. Three quarters of individuals are overweight or obese and those starting antipsychotics experience rapid weight gain in the first 6–12<!--> <!-->months of treatment and this weight gain does not appear to plateau. The high prevalence of modifiable lifestyle risk factors and antipsychotic medication use all contribute to the increased risk of weight gain and cardiovascular disease. Sex may also play a role in the amount of weight gained. Crucially, a 5–10 % reduction in weight has a positive impact on cardiovascular disease risk factors.</div><div>This study aimed to investigate clinically relevant weight loss (CRWL) and its associated factors, separately by sex. This naturalistic longitudinal study examined the weight of 372 men and women with psychotic disorders at baseline and follow-up on average 3.3 years later and compared those who had lost ≥7 % of their baseline weight with those who had not. Results showed 20.3 % of men and 19.9 % of women had CRWL and a different set of factors were observed to be associated with CRWL for each sex. For men, older age, higher baseline weight, and stopping use of antipsychotics compared to use of antipsychotics with a high-risk of weight gain were associated with an increased odds of CRWL. For women, only better quality of sleep was associated with an increased odds of CRWL. Greater understanding of the factors associated with weight loss in men and women with psychotic disorders may inform the development and implementation of targeted strategies.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"277 ","pages":"Pages 102-110"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relations of temporoparietal connectivity with neighborhood social fragmentation in youth at clinical high-risk for psychosis","authors":"Katrina Aberizk ,&nbsp;Esra Sefik ,&nbsp;Qingyue Yuan ,&nbsp;Hengyi Cao ,&nbsp;Jean M. Addington ,&nbsp;Carrie E. Bearden ,&nbsp;Kristin S. Cadenhead ,&nbsp;Tyrone D. Cannon ,&nbsp;Barbara A. Cornblatt ,&nbsp;Matcheri Keshavan ,&nbsp;Daniel H. Mathalon ,&nbsp;Diana O. Perkins ,&nbsp;William S. Stone ,&nbsp;Scott W. Woods ,&nbsp;Elaine F. Walker ,&nbsp;Benson S. Ku","doi":"10.1016/j.schres.2025.02.012","DOIUrl":"10.1016/j.schres.2025.02.012","url":null,"abstract":"<div><div>Temporoparietal brain areas comprise a candidate set of regions for interrogating the brain functional correlates of socioenvironmental factors in people at clinical high-risk for psychosis (CHR-P). Temporal lobe abnormalities have been shown to be common among people with schizophrenia spectrum conditions. Further, temporoparietal brain regions are implicated in tasks relevant to psychosocial outcomes, including coherent autobiographical memory recall and multimodal integration. This report examined relations of hippocampal-temporoparietal functional connectivity with neighborhood-level social fragmentation, a composite of area-level characteristics that measures social cohesion, among youth at CHR-P and healthy comparisons in the second wave of the North American Prodrome Longitudinal Study (<em>n</em> = 146, age = 19.9 ± 3.9, 47 % female). This study also examined whether those relations were moderated by individual-level social engagement in desirable activities. Significant positive relations of neighborhood-level social fragmentation and hippocampal functional connectivity with the superior temporal pole were observed among participants at CHR-P. Moderation analyses demonstrated that those relations were significant only at low and mean levels of individual-level social engagement in participants at CHR-P. Findings contribute to the literature indicating that adverse environmental factors are associated with deviant patterns of brain connectivity. This exploratory research also contributes to future theorizing about neurobiological mechanisms underlying therapeutic interventions involving social engagement that have demonstrated improved functional outcomes for people with psychotic disorders.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"277 ","pages":"Pages 151-158"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in degree centrality and its associated genes: A longitudinal study of patients with schizophrenia undergoing pharmacological treatment","authors":"Linna Zhang ,&nbsp;Chunguo Zhang ,&nbsp;Haohao Yan ,&nbsp;Yiding Han ,&nbsp;Caixia Xu ,&nbsp;Jiaquan Liang ,&nbsp;Runyi Li ,&nbsp;Ningning Chen ,&nbsp;Wenting Liang ,&nbsp;Wei Huang ,&nbsp;Guojun Xie ,&nbsp;Wenbin Guo","doi":"10.1016/j.schres.2025.03.009","DOIUrl":"10.1016/j.schres.2025.03.009","url":null,"abstract":"<div><h3>Background</h3><div>The role of degree centrality (DC) in schizophrenia (SCZ), its trajectory following pharmacological treatment, and its potential as a prognostic biomarker and genetic mechanism remain unclear.</div></div><div><h3>Methods</h3><div>We recruited 51 healthy controls (HC) and 56 patients with SCZ. Additionally, the SCZ patients underwent three months of antipsychotic medication treatment. We collected resting-state functional magnetic resonance imaging data, clinical variables, and conducted analyses using support vector machines, support vector regression, and gene expression correlation analysis.</div></div><div><h3>Results</h3><div>Our study revealed that SCZ patients had generally reduced DC values in the cerebral cortex compared to HC at baseline, with increased DC values observed in the left occipital gyrus. After three months of treatment, SCZ patients exhibited a significant decrease in DC values in the left fusiform gyrus and an increase in the left inferior parietal gyrus. Variations in DC values in SCZ patients were associated with multiple genes, primarily enriched in molecular functions.</div></div><div><h3>Conclusion</h3><div>Changes in DC values in the right inferior occipital/fusiform gyrus and right calcarine/middle occipital gyrus may serve as neuroimaging markers to differentiate between HC and SCZ patients. Additionally, DC values in the left middle/postcentral gyrus could be used to predict treatment outcomes. Transcriptome-neuroimaging spatial correlation analysis provides valuable insights into the neurobiological mechanisms underlying SCZ pathology.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"277 ","pages":"Pages 130-139"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of visual remediation on Ebbinghaus illusion task performance in people with schizophrenia: A preliminary study","authors":"Kaitlyn A. Kaiser ,&nbsp;Judy L. Thompson ,&nbsp;Pamela D. Butler ,&nbsp;Anthony O. Ahmed ,&nbsp;Aaron R. Seitz ,&nbsp;Tarek Sobeih ,&nbsp;Steven M. Silverstein","doi":"10.1016/j.schres.2025.02.011","DOIUrl":"10.1016/j.schres.2025.02.011","url":null,"abstract":"<div><h3>Background</h3><div>Atypical perception of visual illusions is well-documented in schizophrenia (SZ) and thought to be a consequence of impairments in visual processes including perceptual organization (PO). The Ebbinghaus illusion, in which a circle appears larger or smaller depending on the size of surrounding circles, is facilitated by PO, and the extent to which the surrounds (i.e., context) influence perception of the center circle can be considered an index of <em>context sensitivity</em>. In the present study, as part of a broader investigation of the impact of a novel visual remediation (VR) program for people with SZ, the Ebbinghaus illusion was used to explore the effects of VR on context sensitivity.</div></div><div><h3>Methods</h3><div>Participants with SZ (<em>n</em> = 47) were randomly assigned to one of four conditions: VR only, an active control condition (AC), or one of two conditions combining VR and AC. At three assessment points, participants completed a size comparison task based on the Ebbinghaus illusion. Context sensitivity was compared between training groups and with baseline clinical characteristics.</div></div><div><h3>Results</h3><div>At baseline, participants were strongly context sensitive. After training, participants in the VR group, but not the AC-only group, became less influenced by context. The main effect of training group and the group × time interaction terms were not significant. Participants who were less symptomatic at baseline showed the greatest reductions in context sensitivity over time.</div></div><div><h3>Conclusions</h3><div>These findings suggest that an adaptive reduction in the influence of irrelevant context is a potential effect of VR and may reflect improved attentional focus.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"277 ","pages":"Pages 57-64"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of clinical symptoms and symptom structure across different onset ages in schizophrenia inpatients","authors":"Zhaofan Liu ,&nbsp;Xiaoying Wang ,&nbsp;Wenjin Chen ,&nbsp;Junchao Huang ,&nbsp;Jinghui Tong ,&nbsp;Jue Wang ,&nbsp;Ran Liu ,&nbsp;Hu Deng ,&nbsp;Kebing Yang ,&nbsp;Wei Li ,&nbsp;Song Chen ,&nbsp;Ting Xie ,&nbsp;Li Tian ,&nbsp;Fude Yang ,&nbsp;Baopeng Tian ,&nbsp;Yanli Li ,&nbsp;Chiang-Shan R. Li ,&nbsp;Yunlong Tan","doi":"10.1016/j.schres.2025.03.015","DOIUrl":"10.1016/j.schres.2025.03.015","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to explore differences in clinical symptom profiles and symptom network structures of inpatients with schizophrenia among early-onset schizophrenia (EOS), typical-onset schizophrenia (TOS), and late-onset schizophrenia (LOS) patients.</div></div><div><h3>Methods</h3><div>Symptom severity was assessed using the Positive and Negative Syndrome Scale (PANSS) in 654 EOS, 1664 TOS, and 369 LOS inpatients with schizophrenia from an open dataset. Symptom severity comparisons were conducted among the three age of onset groups. Symptom networks were constructed, and measurements such as betweenness and closeness centrality were employed to investigate the interconnectivity between symptoms.</div></div><div><h3>Results</h3><div>EOS inpatients exhibited significantly more severe symptoms compared to TOS and LOS, primarily attributable to more severe negative symptoms and general psychopathology. Analysis of the symptom networks revealed that uncontrolled hostility emerged as a core feature across EOS, TOS, and LOS. In the EOS network, anxiety domain served as bridge symptoms, while positive and disorganized thought were strongly associated with disease manifestations. TOS inpatients exhibited a similar pattern to EOS, but TOS showed higher betweenness and lower closeness in positive and negative symptoms, indicating that these domains play a crucial role in the overall network connectivity. In LOS, positive symptoms showed high betweenness centrality, suggesting their pivotal role in network connectivity.</div></div><div><h3>Conclusions</h3><div>These findings suggest that the symptom severity and symptoms network structure differ across different age of onset groups in schizophrenia inpatients. A deeper understanding of these network-level differences could shed light on the distinct pathogenesis mechanisms and guide the development of personalized treatment strategies for schizophrenia.</div></div><div><h3>Hypothesis</h3><div>It has been consistently observed that inpatients with early-onset schizophrenia (EOS) have poorer treatment outcomes compared to typical-onset schizophrenia patients (TOS), while those with late-onset schizophrenia (LOS) tend to have better outcomes than typical-onset inpatients. The reasons behind these phenomena remain unclear. In this work, we aim to utilize network analysis to uncover potential symptom interactions that may contribute to the different treatment outcomes observed across different ages of onset schizophrenia inpatient groups.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"277 ","pages":"Pages 177-184"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MRI data sharing in psychosis: Key challenges and a new Open Access resource for researchers","authors":"S.L. Evans ,&nbsp;V. Kumari ,&nbsp;M.J. Kempton ,&nbsp;J. Rogers ,&nbsp;R. Upthegrove ,&nbsp;P. Allen","doi":"10.1016/j.schres.2025.03.012","DOIUrl":"10.1016/j.schres.2025.03.012","url":null,"abstract":"","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"277 ","pages":"Pages 185-187"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of tDCS with concurrent cognitive performance targeting the dorsolateral prefrontal cortex and the posterior parietal cortex on EEG microstates in schizophrenia","authors":"Xiangqin Qin ,&nbsp;Qi Wang ,&nbsp;Hang Li ,&nbsp;Jingkun Wang ,&nbsp;Zhen Mao ,&nbsp;Fang Dong ,&nbsp;Qijing Bo ,&nbsp;Fuchun Zhou ,&nbsp;Xianbin Li ,&nbsp;Wenpeng Hou ,&nbsp;Chuanyue Wang","doi":"10.1016/j.schres.2025.03.003","DOIUrl":"10.1016/j.schres.2025.03.003","url":null,"abstract":"<div><h3>Objectives</h3><div>Working memory impairments represent fundamental cognitive deficits in schizophrenia (SZ). Although transcranial direct current stimulation (tDCS) has demonstrated potential in enhancing working memory in SZ, its neural mechanisms and optimized strategies remain to be elucidated. This study explored the effects of tDCS with concurrent cognitive performance targeting the dorsolateral prefrontal cortex (DLPFC) and posterior parietal cortex (PPC) on electroencephalography (EEG) microstates in SZ.</div></div><div><h3>Methods</h3><div>This analysis is based on a randomized, double-blind clinical trial of tDCS with concurrent cognitive performance in SZ. Sixty participants were assigned to three groups: active DLPFC, active PPC, and sham stimulation groups. tDCS was administered concurrently with a visual working memory task. The spatial span test was used to assess working memory at baseline, week 1, and week 2, with resting-state EEG data collected at each time point.</div></div><div><h3>Results</h3><div>No significant differences were detected in the characteristics of the four microstates (A, B, C, and D) at baseline. Compared with the sham stimulation group, the active DLPFC and PPC groups exhibited significant improvements in the duration, occurrence, and coverage of microstate B at week 2. However, the changes in the parameters of microstate B at week 2 were not significantly correlated with working memory improvement.</div></div><div><h3>Conclusions</h3><div>This study suggests that neuromodulation targeting different nodes within the task-induced network may influence the same subnetworks in SZ. This work provides new insights into network-based interventions and contributes to the development of multitarget intervention strategies under task conditions.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"277 ","pages":"Pages 117-123"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143562670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling distinct representations of P3a in schizophrenia through two-stimulus and three-stimulus auditory oddball paradigms","authors":"Chenguang Jiang ,&nbsp;Jun Wang ,&nbsp;Yifan Sun ,&nbsp;Shuping Tan ,&nbsp;Shaun M. Percell ,&nbsp;the GRINS consortium,&nbsp;Zhenhe Zhou ,&nbsp;Jen Q. Pan ,&nbsp;Mei-Hua Hall","doi":"10.1016/j.schres.2025.03.004","DOIUrl":"10.1016/j.schres.2025.03.004","url":null,"abstract":"<div><h3>Background</h3><div>P3a event-related potential (ERP) is considered a potential biomarker for schizophrenia (SZ), can be elicited through both passive two-stimulus and active three-stimulus auditory oddball paradigms. While both types of P3a reflect involuntary attention shifts, the nuanced understanding of what P3a represents in different contexts is important and rarely studied. This study aims to examine correlations between P3a ERPs elicited from different paradigms and associations of each P3a with cognitive function, clinical symptoms, and antipsychotic medication.</div></div><div><h3>Methods</h3><div>Our sample included 178 SZ patients and 127 healthy controls (HC). Data on two-stimulus paradigm, three-stimulus oddball paradigm, Chinese version of MATRICS Consensus Cognitive Battery (MCCB), symptom severity, and medication use were collected.</div></div><div><h3>Results</h3><div>In both paradigms, SZ group's P3a amplitude was significantly reduced compared to HC's (both <em>p</em> &lt; 0.05). P3a evoked by the two-stimulus paradigm and the three-stimulus paradigm were not correlated (<em>r</em> = −0.06, <em>p</em> = 0.661). Three-stimulus paradigm-P3a was significantly correlated with attention/vigilance (<em>r</em> = 0.27, <em>p</em> = 0.017) in SZ, and with working memory (<em>r</em> = 0.39, <em>p</em> = 0.001) and overall MCCB score (<em>r</em> = 0.25, <em>p</em> = 0.042) in HC. Additionally, the two-stimulus paradigm-P3a correlated with olanzapine equivalent antipsychotic dose (<em>r</em> = −0.26, <em>p</em> = 0.022).</div></div><div><h3>Conclusions</h3><div>Our findings offer new insights into the role of P3a in clinical research. P3a ERPs from different paradigms may represent functionally distinct components. The context in which the P3a is elicited should be taken into account when discussing its functional or neurocognitive significance.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"277 ","pages":"Pages 159-168"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143593921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}