Revista Brasileira de Psiquiatria最新文献

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Virtual reality, social intelligence, mirror neurons and bipolar spectrum a new perspective. 虚拟现实、社交智能、镜像神经元和躁郁症谱的新视角。
IF 3.6 3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2024-11-17 DOI: 10.47626/1516-4446-2024-3901
Mauro G Carta, Antonio E Nardi
{"title":"Virtual reality, social intelligence, mirror neurons and bipolar spectrum a new perspective.","authors":"Mauro G Carta, Antonio E Nardi","doi":"10.47626/1516-4446-2024-3901","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3901","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Signal Mining and Risk Analysis of Olanzapine Adverse Events in the FAERS Database. FAERS 数据库中奥氮平不良事件的信号挖掘和风险分析。
IF 3.6 3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2024-11-17 DOI: 10.47626/1516-4446-2024-3880
Aiguo Dong, Lingyi Shi, Zhiqiang Du, Qin Zhou, Ying Jiang, Haohao Zhu, Anqing Zhu
{"title":"Signal Mining and Risk Analysis of Olanzapine Adverse Events in the FAERS Database.","authors":"Aiguo Dong, Lingyi Shi, Zhiqiang Du, Qin Zhou, Ying Jiang, Haohao Zhu, Anqing Zhu","doi":"10.47626/1516-4446-2024-3880","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3880","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to assess the safety profile of Olanzapine by analyzing adverse events (AEs) reported in the FAERS database, particularly focusing on newly identified risks.</p><p><strong>Method: </strong>The study involved adverse events (AEs) related to Olanzapine from January 1, 2004, to June 30, 2023. Four signal mining methods were used for a comprehensive analysis of the frequency and strength of AEs, including ROR, PRR, BCPNN, and EBGM.</p><p><strong>Results: </strong>A total of 43,664 reports with Olanzapine as the primary suspect drug were collected. 776 PT signals involving 27 SOCs were identified. The main affected groups were females and the age group of 18 to 45 years. Psychiatric disorders and Nervous system disorders were the most common adverse reactions. Moreover, the analysis revealed some adverse reactions not recorded in the manual, including cardiovascular risks like Pancreatitis, Chylomicron increased, Hyperchylomicronaemia, and Myocardial reperfusion injury, as well as rare but serious adverse reactions like Neuroleptic malignant syndrome and Anosognosia.</p><p><strong>Conclusion: </strong>This study identified new cardiovascular risks associated with Olanzapine, including pancreatitis and myocardial reperfusion injury, which require further investigation.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142648420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A randomized, double-blind, placebo-controlled trial of N-acetylcysteine as an adjuvant treatment for alcohol use disorder. N-乙酰半胱氨酸作为酒精使用障碍辅助治疗的随机、双盲、安慰剂对照试验。
IF 3.6 3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2024-10-09 DOI: 10.47626/1516-4446-2024-3541
Jaqueline B Schuch, Fernanda Hansen, Thiago Hartmann, Daniela Benzano, Henrique M Gomes, José Cláudio F Moreira, Flavio Pechansky, Felix H P Kessler, Fabiana Galland, Daiane Silvello, Anne O Sordi, Lisia von Diemen
{"title":"A randomized, double-blind, placebo-controlled trial of N-acetylcysteine as an adjuvant treatment for alcohol use disorder.","authors":"Jaqueline B Schuch, Fernanda Hansen, Thiago Hartmann, Daniela Benzano, Henrique M Gomes, José Cláudio F Moreira, Flavio Pechansky, Felix H P Kessler, Fabiana Galland, Daiane Silvello, Anne O Sordi, Lisia von Diemen","doi":"10.47626/1516-4446-2024-3541","DOIUrl":"10.47626/1516-4446-2024-3541","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to assess the effect of N-acetylcysteine (NAC), as an adjuvant treatment, on treatment adherence (primary outcome), in peripheral biomarkers and clinical improvement (secondary outcomes) in alcohol use disorders (AUD) patients.</p><p><strong>Methods: </strong>A 9-week randomized, double-blind, placebo-controlled trial (RCT) was conducted on 53 (n=25 NAC, n=28 placebo) inpatients with AUD. Neuropeptide Y (NPY), oxidative stress and inflammatory biomarkers, and hepatic parameters were analyzed in three-time moments.</p><p><strong>Results: </strong>Seventeen (60.7%) subjects in placebo and sixteen (64%) in the NAC group completed the RCT. Levels of hepatic biomarkers significantly changed over time (p<0.001). Oxidized glutathione (GSSG) levels at admission were lower in NAC group ((ppairwise=0.043). By the end of the study, both groups had similar GSSG levels (p=0.868), showing a reduction in GSSG levels in the placebo group. In the NAC group, a decrease in superoxide dismutase (SOD) activity and an increase in NPY levels in the end of the intervention were observed. Both groups showed similar mean survival time to relapse, treatment adherence and clinical improvement.</p><p><strong>Conclusion: </strong>Our findings reinforce the alcohol effects on oxidative stress and NPY parameters. However, our sample size may limit the generalizability of the results, especially for clinical outcomes. Future RCTs with less severe alcoholics and longer follow-up may be necessary to test if NAC could be helpful to reduce the mental health burden related to AUD.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142648433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Download to Heal: Navigating the Pixelated Path of Digital Therapeutics in Psychiatric Care. 下载《治愈:探索精神病治疗中数字疗法的像素之路》(Digital Therapeutics in Psychiatric Care)。
IF 3.6 3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2024-09-27 DOI: 10.47626/1516-4446-2024-3802
Jai Ahuja, Sanobar Jaka, Sikandar Saeed, Sasidhar Gunturu
{"title":"Download to Heal: Navigating the Pixelated Path of Digital Therapeutics in Psychiatric Care.","authors":"Jai Ahuja, Sanobar Jaka, Sikandar Saeed, Sasidhar Gunturu","doi":"10.47626/1516-4446-2024-3802","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3802","url":null,"abstract":"<p><p>Digital therapeutics have evolved rapidly with technological advances in healthcare. Despite their increasing use, gaps remain in understanding their regulatory frameworks, integration, and efficacy for conditions like substance use disorder, insomnia, attention deficit hyperactivity disorder, and post-traumatic stress disorder. This study evaluates FDA-approved digital therapeutics and explores their potential to revolutionize psychiatric treatments amid ongoing technological and regulatory changes. We conducted a comprehensive review of major databases, focusing on articles published up to January 2024 on FDA-approved digital therapeutics. We excluded non-English articles and those lacking empirical data or focusing on non-FDA-approved therapeutics. Our analysis covered regulatory compliance, clinical outcomes, and integration with traditional treatments. The review of nine FDA-cleared digital therapeutics revealed benefits like improved treatment accessibility and potential reductions in healthcare costs. For example, Somryst, a cognitive-behavioral therapy-based treatment for insomnia, showed that over 40 percent of users overcame chronic insomnia, and 60 percent experienced improvements without adverse effects. However, challenges remain, including low provider adoption, inadequate insurance coverage, and high user dropout rates. While digital therapeutics enhance accessibility, they face regulatory challenges, reimbursement issues, and the need for robust clinical evidence. Success depends on collaboration among stakeholders to demonstrate value, ensure safety, and integrate them into existing healthcare systems.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142352901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parenthood and All-cause Mortality in Older Adults with Schizophrenia: A Multicenter 5-Year Prospective Study. 父母身份与老年精神分裂症患者的全因死亡率:一项为期 5 年的多中心前瞻性研究。
IF 3.6 3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2024-09-27 DOI: 10.47626/1516-4446-2024-3731
Katayoun Rezaei, Sandra Abou Kassm, María Sofía Garcés-González, Marina Sánchez-Rico, Mark Olfson, Charles Ouazana-Vedrines, Valentin Scheer, Mahdi Fayad, Pierre Meneton, Frédéric Limosin, Nicolas Hoertel
{"title":"Parenthood and All-cause Mortality in Older Adults with Schizophrenia: A Multicenter 5-Year Prospective Study.","authors":"Katayoun Rezaei, Sandra Abou Kassm, María Sofía Garcés-González, Marina Sánchez-Rico, Mark Olfson, Charles Ouazana-Vedrines, Valentin Scheer, Mahdi Fayad, Pierre Meneton, Frédéric Limosin, Nicolas Hoertel","doi":"10.47626/1516-4446-2024-3731","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3731","url":null,"abstract":"<p><strong>Objective: </strong>The large body of literature examining the association between parenthood and mortality in the general population contrasts with a lack of studies among older adults with schizophrenia. Identifying potential protective factors of premature death in this population is important to help guide prevention measures. Here, we examined whether all-cause and cause-specific mortality rates significantly differ between older adults with schizophrenia with and without children, during a 5-year follow-up.</p><p><strong>Methods: </strong>We used data from a 5-year prospective multicenter sample of older adults with an ICD-10 diagnosis of schizophrenia (aged 55 years or more) recruited in France. We performed a forward stepwise logistic regression to examine the association between parenthood and all-cause mortality, including only those independent variables that best explain outcome.</p><p><strong>Results: </strong>Of 323 older adults with schizophrenia, 133 (41.2%) had children (mean age=67.0, SD=6.1), whereas 190 were without children (mean age=67.2, SD=6.6). Following adjustments, parenthood was significantly associated with lower all-cause mortality compared to patients without children in this population (21.1% (n=28) versus 35.8% (n=68); AOR=0.50; 95%CI=0.27-0.94; p=0.032), without significant sex differences in this association.</p><p><strong>Conclusions: </strong>Parenthood could be protective against mortality among older patients with schizophrenia who live in France. Further research is needed to understand the specific mechanisms underlying this association.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142352923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of home-based transcranial direct current stimulation combined with nutritional counseling therapy on binge eating disorder symptoms: A randomized pilot trial. 家庭经颅直流电刺激结合营养咨询疗法对暴食症症状的影响:随机试验
IF 3.6 3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2024-09-25 DOI: 10.47626/1516-4446-2024-3776
Jessica Lorenzzi Elkfury, Luciana C Antunes, Betina Franceschini Tocchetto, Lizia Nardi Menegassi, Paulo Sanches, Danton Pereira, Liciane Fernandes Medeiros, Tiago M Cardinal, Iraci Lucena da Silva Torres, Felipe Fregni, Wolnei Caumo
{"title":"Effect of home-based transcranial direct current stimulation combined with nutritional counseling therapy on binge eating disorder symptoms: A randomized pilot trial.","authors":"Jessica Lorenzzi Elkfury, Luciana C Antunes, Betina Franceschini Tocchetto, Lizia Nardi Menegassi, Paulo Sanches, Danton Pereira, Liciane Fernandes Medeiros, Tiago M Cardinal, Iraci Lucena da Silva Torres, Felipe Fregni, Wolnei Caumo","doi":"10.47626/1516-4446-2024-3776","DOIUrl":"10.47626/1516-4446-2024-3776","url":null,"abstract":"<p><strong>Objective: </strong>To examine the effect of nutritional counseling therapy (NCT) combined with transcranial direct current stimulation (tDCS) on Binge Eating Disorder (BED) symptoms.</p><p><strong>Methods: </strong>40 women with BED were randomly (ratio of 2:2:2) allocated to one of the groups: active tDCS (a-tDCS), NCT, sham tDCS (s-tDCS) with NCT, and a-tDCS with NCT. Home-based tDCS was applied to the dorsolateral prefrontal cortex for 28 sessions.</p><p><strong>Results: </strong>A mixed analysis of variance showed no main effect between groups or a time × group interaction. However, a significant main effect was found for time on the primary outcome: Binge Eating Scale (p = 0.001; eta2p= 0.325), which tended to decrease during treatment and follow-up. A significant main effect was found on the secondary outcome: short-interval intracortical inhibition (SICI) (p = 0.02; eta2p= 0.112), a measure of inhibitory function, which increased from baseline to the final period in the a-tDCS group, without significant differences between groups.</p><p><strong>Conclusions: </strong>These findings reveal that the combined therapy did not have a synergic effect on BED symptoms. Since this is a pilot study and this is a promising area, we provide data to plan future larger-scale studies investigating the effects of tDCS and behavioral interventions in BED treatment.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142352902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal Gut Microbiota Composition During Perinatal period in Women with Different Intensities of Depressive Symptoms. 不同抑郁症状强度妇女围产期的纵向肠道微生物群组成
IF 3.6 3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2024-09-21 DOI: 10.47626/1516-4446-2024-3721
Amanda S Mota, Luiz Gustavo Sparvoli, Pedro Augusto R Vanzele, Nathalia F Naspolini, Eric de Castro Tobaruela, Carlos T Yoshizaki, Rossana Pulcineli Vieira Francisco, Ana Maria S S Oliveira, Marco Aurélio Knippel Galletta, Vera Lucia C Tess, Carla R Taddei
{"title":"Longitudinal Gut Microbiota Composition During Perinatal period in Women with Different Intensities of Depressive Symptoms.","authors":"Amanda S Mota, Luiz Gustavo Sparvoli, Pedro Augusto R Vanzele, Nathalia F Naspolini, Eric de Castro Tobaruela, Carlos T Yoshizaki, Rossana Pulcineli Vieira Francisco, Ana Maria S S Oliveira, Marco Aurélio Knippel Galletta, Vera Lucia C Tess, Carla R Taddei","doi":"10.47626/1516-4446-2024-3721","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3721","url":null,"abstract":"<p><strong>Background: </strong>Depressive symptoms during perinatal significantly impact mothers and infants. Emerging evidence suggests a connection between gut microbiota and mood regulation. This study investigated whether depressive symptoms are associated with changes in the gut microbiota of women during the perinatal period.</p><p><strong>Method: </strong>A total of 34 pregnant women were screened for depression using the Edinburgh Postnatal Depression Scale (EPDS) and categorized based on symptom severity. Stool samples were collected during the third trimester and at two postpartum timepoints. All samples underwent 16S rRNA gene sequencing and Quantification of Short-Chain Fatty Acids (SCFA) using a gas chromatograph-mass spectrometer (GC-MS).</p><p><strong>Results: </strong>No differences in SCFA concentrations were observed between groups (p>0.05). However, postpartum women with moderate to severe symptoms (MG group) had a significant increase in Enterobacteriaceae abundance compared to the mild and absent group (AL group) (p<0.05). The Bifidobacterium genus increased significantly in both groups over time (p<0.05). The MG group showed a reduction in depressive symptoms during psychiatric treatment (p<0.05).</p><p><strong>Conclusion: </strong>These findings suggest a link between gut microbiota and perinatal depressive symptoms. Further research is needed to understand the broader implications for maternal health through microbiome-targeted approaches.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Internalizing problems can differ in boys and girls since early childhood: Findings from the Child Behavioral Checklist 1.5-5 (CBCL 1.5-5). 男孩和女孩的内化问题在童年早期就可能存在差异:儿童行为检查表 1.5-5 (CBCL 1.5-5) 的研究结果。
IF 3.6 3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2024-08-18 DOI: 10.47626/1516-4446-2024-3616
Adriana Maldonado Martinez, Sheila C Caetano, Marcos V Ribeiro, Alexandra Restrepo-Henao, Paola M Okuda, Thiago M Fidalgo, Pamela J Surkan, Luis Manuel Silva, Silvia S Martins
{"title":"Internalizing problems can differ in boys and girls since early childhood: Findings from the Child Behavioral Checklist 1.5-5 (CBCL 1.5-5).","authors":"Adriana Maldonado Martinez, Sheila C Caetano, Marcos V Ribeiro, Alexandra Restrepo-Henao, Paola M Okuda, Thiago M Fidalgo, Pamela J Surkan, Luis Manuel Silva, Silvia S Martins","doi":"10.47626/1516-4446-2024-3616","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3616","url":null,"abstract":"<p><strong>Background: </strong>Globally, internalizing problems disproportionately affect females in adolescence and adulthood, with limited research at earlier ages due to a focus on disruptive behaviors. Our study addresses this gap by exploring the structure of internalizing problems and gender differences in Brazilian preschoolers.</p><p><strong>Methods: </strong>We analyzed data from the Child Behavioral Checklist 1.5-5 in the Preschool Mental Health Study, involving 1,292 children aged 4 to 5 in Embu das Artes, São Paulo, Brazil. Confirmatory factor analysis and mean comparisons explored internalizing problems and gender variations.</p><p><strong>Results: </strong>A two-factor model best fit both internalizing and externalizing problems.The hierarchical model with four factors (Emotionally Reactive, Anxiety/Depression, Somatic Complaints, and Withdrawn) best fit internalizing problems, achieving partial invariance between boys and girls. Boys scored higher in Withdrawn Syndrome, while girls scored higher in Somatic Complaints Syndrome.</p><p><strong>Conclusions: </strong>Preschoolers' internalizing problems warrant attention beyond their link to externalizing problems. While the overall construct is similar in boys and girls, divergent syndrome scores indicate potential distinct risk patterns requiring further exploration.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of online group cognitive behavioral therapy for adolescents with obsessive-compulsive disorder: a pilot study. 在线认知行为疗法对强迫症青少年的疗效:一项试点研究。
IF 3.6 3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2024-01-01 Epub Date: 2024-02-19 DOI: 10.47626/1516-4446-2023-3376
Cristiane Flores Bortoncello, Nicolas de Oliveira Cardoso, Sophia Ronchetti Martins Xavier, Ygor Arzeno Ferrão
{"title":"Effectiveness of online group cognitive behavioral therapy for adolescents with obsessive-compulsive disorder: a pilot study.","authors":"Cristiane Flores Bortoncello, Nicolas de Oliveira Cardoso, Sophia Ronchetti Martins Xavier, Ygor Arzeno Ferrão","doi":"10.47626/1516-4446-2023-3376","DOIUrl":"10.47626/1516-4446-2023-3376","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effectiveness of online group cognitive behavioral therapy (CBT) based on the CAMALEO TOC manual in the treatment of adolescents with obsessive-compulsive disorder (OCD).</p><p><strong>Methods: </strong>This is a quasi-experimental study with a single-group pretest-posttest intervention. Over a 12-week period, 11 adolescents aged 11 to 17 years with OCD participated in weekly online group CBT sessions based on the CAMALEO TOC manual. We used several assessment tools, including the Children's Yale-Brown Obsessive-Compulsive Scale to assess the severity of OCD symptoms, the Family Accommodation Scale for Obsessive-Compulsive Disorder-Interviewer-Rated to measure family accommodation, the Children's Depression Inventory to assess depression symptoms, the Revised Children's Manifest Anxiety Scale to assess anxiety, and the Multidimensional Students' Life Satisfaction Scale to measure satisfaction with life.</p><p><strong>Results: </strong>OCD symptoms decreased significantly (d = -1.55) after online group CBT, and a strong effect size (d = -1.03) was found for family accommodation. After controlling for variables (e.g., engagement in psychotherapeutic treatment, medication use, or psychiatric comorbidities), no significant differences were found for OCD symptoms and family accommodation scores. In addition, there was insufficient evidence to support the effectiveness of online group CBT in reducing symptoms of depression or anxiety or improving overall quality of life.</p><p><strong>Conclusion: </strong>Our study demonstrates the feasibility of short-term online group CBT as an effective therapeutic approach for adolescents with OCD.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20233376"},"PeriodicalIF":3.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are we correctly diagnosing and screening for bipolar depression? 我们是否正确诊断和筛查了双相抑郁症?
IF 3.6 3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2024-01-01 Epub Date: 2024-11-15 DOI: 10.47626/1516-4446-2024-3808
Adriana Munhoz Carneiro, Fernando Dos Santos Fernandes, Ricardo Alberto Moreno, Doris Hupfeld Moreno
{"title":"Are we correctly diagnosing and screening for bipolar depression?","authors":"Adriana Munhoz Carneiro, Fernando Dos Santos Fernandes, Ricardo Alberto Moreno, Doris Hupfeld Moreno","doi":"10.47626/1516-4446-2024-3808","DOIUrl":"10.47626/1516-4446-2024-3808","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20243808"},"PeriodicalIF":3.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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