Revista Brasileira de Psiquiatria最新文献_第4页

Short and Long-term Effects of Cognitive Behavioral Therapy on Sleep Problems and Psychotic Symptoms in Patients with Psychotic Disorders: A Meta-Analysis Study. 认知行为疗法对精神障碍患者睡眠问题和精神症状的短期和长期影响：一项元分析研究

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-08-05 DOI: 10.47626/1516-4446-2024-3623

Mustafa Ugurlu, Gorkem Karakas Ugurlu, Esra Kabadayi Sahin, Gulsum Zuhal Kamis, Ali Caykoylu

{"title":"Short and Long-term Effects of Cognitive Behavioral Therapy on Sleep Problems and Psychotic Symptoms in Patients with Psychotic Disorders: A Meta-Analysis Study.","authors":"Mustafa Ugurlu, Gorkem Karakas Ugurlu, Esra Kabadayi Sahin, Gulsum Zuhal Kamis, Ali Caykoylu","doi":"10.47626/1516-4446-2024-3623","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3623","url":null,"abstract":"Objective: Sleep problems are common in patients with psychotic disorders, especially schizophrenia. Although pharmacological methods are at the forefront of treatment, this method has some drawbacks. Cognitive behavioral therapy for insomnia (CBT-I) is an option for the treatment of individuals with insomnia. In recent years, there has been an increasing interest in its use in patients with psychotic disorders. This meta-analysis aims to evaluate the effectiveness of CBT-I on sleep problems in patients with psychotic disorders.Methods: A systematic search was conducted using PubMed, Scopus, and EBSCO (MEDLINE) databases to identify relevant studies. The study included RCTs and uncontrolled studies that focused on participants diagnosed with schizophrenia, schizoaffective disorder, delusional disorder, psychotic disorders not otherwise specified, bipolar disorders, or unipolar depression with psychotic features, who had sleep problems for at least one month, and who were receiving treatment. The initial search yielded 246 studies, and eight studies were selected for the meta-analysis after screening and applying inclusion and exclusion criteria.The statistical analysis was conducted using the R software.Results: CBT-I significantly ameliorates insomnia and sleep quality in patients with psychotic disorders during short and long-term periods. In addition to this, CBT-I leads to a significant improvement in psychotic symptoms in the short-term period and contributes significantly to the improvement in mental well-being in both short and long-term periods.Conclusions: CBT-I is an effective and valuable method for sleep problems in patients with psychotic disorders and its use is recommended to be widespread.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A hybrid model for predicting response to risperidone after first episode of psychosis. 预测首次精神病发作后对利培酮反应的混合模型。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-07-29 DOI: 10.47626/1516-4446-2024-3608

Giovany Oliveira Costa, Vanessa K Ota, Matheus Rodrigues Luiz, Joice Santos Rosa, Gabriela Xavier, Jessica Honorato Mauer, Marcos L Santoro, Carolina Muniz Carvalho, Daniel A Cavalcante, Amanda V G Bugiga, Rodrigo A Bressan, Gerome Breen, Ary Gadelha, Cristiano Noto, Diego R Mazzotti, Sintia I Belangero

{"title":"A hybrid model for predicting response to risperidone after first episode of psychosis.","authors":"Giovany Oliveira Costa, Vanessa K Ota, Matheus Rodrigues Luiz, Joice Santos Rosa, Gabriela Xavier, Jessica Honorato Mauer, Marcos L Santoro, Carolina Muniz Carvalho, Daniel A Cavalcante, Amanda V G Bugiga, Rodrigo A Bressan, Gerome Breen, Ary Gadelha, Cristiano Noto, Diego R Mazzotti, Sintia I Belangero","doi":"10.47626/1516-4446-2024-3608","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3608","url":null,"abstract":"Patient response to antipsychotic drugs varies and may be related to clinical and genetic heterogeneity. This study aimed to determine the performance of clinical, genetic, and hybrid models to predict the response of first episode of psychosis (FEP). patients to the antipsychotic risperidone. We evaluated 141 antipsychotic-naïve FEP patients before and after 10 weeks of risperidone treatment. Patients who had a response rate equal to or higher than 50% on the Positive and Negative Syndrome Scale were considered responders (n = 72; 51%). Analyses were performed using a support vector machine (SVM), k-nearest neighbors (kNN), and random forests (RF). Clinical and genetic (with single-nucleotide variants [SNVs]) models were created separately. Hybrid models (clinical+genetic factors) with and without feature selection were created. Clinical models presented greater balanced accuracy 63.3% (confidence interval [CI] 0.46-0.69) with the SVM algorithm than the genetic models (balanced accuracy: 58.5% [CI 0.41-0.76] - kNN algorithm). The hybrid model, which included duration of untreated psychosis, Clinical Global Impression-Severity scale scores, age, cannabis use, and 406 SNVs, showed the best performance (balanced accuracy: 72.9% [CI 0.62-0.84] - RF algorithm). A hybrid model, including clinical and genetic predictors, can provide enhanced predictions of response to antipsychotic treatment.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations of Adult ADHD symptoms with binge eating spectrum conditions, psychiatric and somatic comorbidity, and healthcare utilization in a metropolitan Brazilian city. 巴西某大都市成人多动症症状与暴饮暴食谱系疾病、精神病和躯体疾病合并症以及医疗保健利用率之间的关系。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-07-29 DOI: 10.47626/1516-4446-2024-3728

Jose Carlos Appolinario, Carlos Eduardo F de Moraes, Rosely Sichieri, Phillipa Hay, Stephen V Faraone, Paulo Mattos

{"title":"Associations of Adult ADHD symptoms with binge eating spectrum conditions, psychiatric and somatic comorbidity, and healthcare utilization in a metropolitan Brazilian city.","authors":"Jose Carlos Appolinario, Carlos Eduardo F de Moraes, Rosely Sichieri, Phillipa Hay, Stephen V Faraone, Paulo Mattos","doi":"10.47626/1516-4446-2024-3728","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3728","url":null,"abstract":"Objectives: To investigate the associations among symptoms of attention deficit hyperactivity disorder (ADHD) with binge eating spectrum conditions - BESC - [binge eating disorder (BED), bulimia nervosa (BN), and recurrent binge eating (RBE)], and psychiatric and somatic comorbidity and healthcare utilization in a representative sample of a Brazilian city.Methods: A household survey with 2,297 adults and residents in Rio de Janeiro was conducted. The Adult Self-Rating Scale Screener was used to assess ADHD symptoms. BESC was assessed using the Questionnaire of Eating and Weight Patterns 5 and confirmed by telephone interview. Standardized questionnaires were used to assess psychiatric comorbidity. Close-ended questions investigated somatic comorbidity and healthcare utilization.Results: ADHD symptoms were highly associated with BESC [BED, OR=13.2, 95%CI= 4.3-40.6; BN, OR=27.5, 95%CI= 5.9-128.7; RBE, OR=5.8, 95%CI= 2.9-11.4). However, with further adjustment for psychiatric comorbidity (depression, anxiety, alcohol use and impulsivity), the ORs were no longer significant. Healthcare resource utilization was significantly higher in participants with ADHD and BESC but lost significance after controlling for the psychiatric comorbidity.Conclusion: ADHD was associated with an increased prevalence of BESC, and healthcare utilization. Nonetheless, there was an essential interplay among psychiatric comorbidity in the associations of ADHD and BESC.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Efficacy and Safety of Complementary and Alternative Medicine for Depression: An Umbrella Review. 补充和替代医学治疗抑郁症的有效性和安全性：综述》。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-07-29 DOI: 10.47626/1516-4446-2024-3705

Yiting Liu, Rongfei Yang, Nana Zhang, Qingshan Liu

{"title":"The Efficacy and Safety of Complementary and Alternative Medicine for Depression: An Umbrella Review.","authors":"Yiting Liu, Rongfei Yang, Nana Zhang, Qingshan Liu","doi":"10.47626/1516-4446-2024-3705","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3705","url":null,"abstract":"Objective: Depression is a major public health problem. Many complementary and alternative medicine (CAM) interventions have been suggested as potential treatments.Methods: We comprehensively searched for relevant systematic reviews and meta-analyses in the PubMed, EMBASE, Web of Science, and Cochrane Library databases. We assessed effectiveness based on efficiency and changes in Depression Assessment Scale scores and safety based on adverse events.Results: This umbrella review included twenty-two eligible articles. Yueju antidepressant and Electro-acupuncture (EA) improved depression symptoms better than antidepressants. In addition, omega-3 fatty acids (n-3PUFAs), exercise, manual acupuncture (MA), Hypericum mono-preparations, relaxation, and Vitamin D showed better efficacy than placebo and control. GPD as adjunctive therapies have higher efficacy rates than antidepressant, and MA and Yueju antidepressants have a better safety profile than antidepressants.Conclusion: Our study demonstrated that 10 CAMs can effectively improve the condition of patients with clinical depression.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Natural language processing in at-risk mental states: enhancing the assessment of thought disorders and psychotic traits with semantic dynamics and graph theory. 高危精神状态下的自然语言处理：利用语义动力学和图论加强对思维障碍和精神病特征的评估。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-07-29 DOI: 10.47626/1516-4446-2023-3419

Felipe Argolo, William Henrique de Paula Ramos, Natalia Bezerra Mota, João Medrado Gondim, Ana Caroline Lopes-Rocha, Julio Cesar Andrade, Martinus Theodorus van de Bilt, Leonardo Peroni de Jesus, Andrea Jafet, Guillermo Cecchi, Wagner Farid Gattaz, Cheryl Mary Corcoran, Anderson Ara, Alexandre Andrade Loch

{"title":"Natural language processing in at-risk mental states: enhancing the assessment of thought disorders and psychotic traits with semantic dynamics and graph theory.","authors":"Felipe Argolo, William Henrique de Paula Ramos, Natalia Bezerra Mota, João Medrado Gondim, Ana Caroline Lopes-Rocha, Julio Cesar Andrade, Martinus Theodorus van de Bilt, Leonardo Peroni de Jesus, Andrea Jafet, Guillermo Cecchi, Wagner Farid Gattaz, Cheryl Mary Corcoran, Anderson Ara, Alexandre Andrade Loch","doi":"10.47626/1516-4446-2023-3419","DOIUrl":"10.47626/1516-4446-2023-3419","url":null,"abstract":"Objective: Verbal communication has key information for mental health evaluation. Researchers have linked psychopathology phenomena to some of their counterparts in natural-language-processing (NLP). We study the characterization of subtle impairments presented in early stages of psychosis, developing new analysis techniques and a comprehensive map associating NLP features with the full range of clinical presentation.Methods: We used NLP to assess elicited and free-speech of 60 individuals in at-risk-mental-states (ARMS) and 73 controls, screened from 4,500 quota-sampled Portuguese speaking citizens in Sao Paulo, Brazil. Psychotic symptoms were independently assessed with Structured-Interview-for-Psychosis-Risk-Syndromes (SIPS). Speech features (e.g.sentiments, semantic coherence), including novel ones, were correlated with psychotic traits (Spearman's-ρ) and ARMS status (general linear models and machine-learning ensembles).Results: NLP features were informative inputs for classification, which presented 86% balanced accuracy. The NLP features brought forth (e.g. Semantic laminarity as 'perseveration', Semantic recurrence time as 'circumstantiality', average centrality in word repetition graphs) carried most information and also presented direct correlations with psychotic symptoms. Out of the standard measures, grammatical tagging (e.g. use of adjectives) was the most relevant.Conclusion: Subtle speech impairments can be grasped by sensitive methods and used for ARMS screening. We sketch a blueprint for speech-based evaluation, pairing features to standard thought disorder psychometric items.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brazil Tightens the Reins on Z-Drugs: New Regulations for Zolpidem and Eszopiclone. 巴西收紧对 Z 类药物的管制：唑吡坦和艾佐匹克隆的新法规。

3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-06-15 DOI: 10.47626/1516-4446-2024-3732

Marcelo G Lima, Vitor S Tardelli, Thiago M Fidalgo

引用次数: 0

Social skills in patients with obsessive-compulsive disorder before and after treatment. 强迫症患者在治疗前后的社交技能。

3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-06-14 DOI: 10.47626/1516-4446-2024-3577

Felipe C da Silva, Marcelo C Batistuzzo, Juliana B Diniz, Carina C D'Alcante, Kiara Timpano, Roseli G Shavitt, Euripedes C Miguel, Marcelo Q Hoexter

{"title":"Social skills in patients with obsessive-compulsive disorder before and after treatment.","authors":"Felipe C da Silva, Marcelo C Batistuzzo, Juliana B Diniz, Carina C D'Alcante, Kiara Timpano, Roseli G Shavitt, Euripedes C Miguel, Marcelo Q Hoexter","doi":"10.47626/1516-4446-2024-3577","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3577","url":null,"abstract":"Objective: We aim to investigate whether: 1) social skills (SS) are impaired in obsessive-compulsive disorder (OCD); 2) SS would change over the course of treatment; and 3) severity of OCD, age of onset of OCD symptoms and illness duration would be associated with SS impairments.Methods: 41 treatment-naive patients with OCD and 34 control participants (CP) were assessed using a SS inventory. Patients were reevaluated 12-weeks after standardized treatment. Group differences, as well as the treatment effect on OCD symptomatology over time, were analyzed with independent and paired tests, respectively. OCD severity, age at illness onset and illness duration were tested as predictors of SS.Results: Patients had lower total SS scores compared to controls (p-value < 0.001). After treatment, although OCD symptomatology (p-value < 0.001) improved, there was no statistical difference in SS performance (p-value = 0.673). Earlier age of onset of OCD symptoms predicted worse SS total score (p-value = 0.016).Conclusion: This study suggests that, despite the amelioration of OCD symptomatology, there was no alteration in Social Skills (SS) performance. Subsequent treatment investigations incorporating larger sample sizes and extended follow-up periods could elucidate whether enhancements in social skills are likely to manifest over time.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early adolescent life-related factors and predictors of violent behavior. 青少年早期生活相关因素和暴力行为的预测因素。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-06-14 DOI: 10.47626/1516-4446-2024-3719

Mei-Ju Chen, Shiuan-Shinn Lee, Shu-Hsin Lee

引用次数: 0

The Rise of the inadvertently called Adolescent 'Zombie' Behavior: A Spotlight on Synthetic Cannabinoid Abuse. 青少年 "僵尸 "行为的兴起：聚焦合成大麻素滥用。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-06-14 DOI: 10.47626/1516-4446-2024-3587

Pedro Mendonça-Ferreira, Henrique Bombana, João Mauricio Castaldelli-Maia

引用次数: 0

Abnormal Insula Network Characteristics in Panic Disorder. 恐慌症中异常的脑岛网络特征

3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-06-06 DOI: 10.47626/1516-4446-2023-3520

Linlin You, Wenhao Jiang, Taipeng Sun, Yue Zhou, Gang Chen, Wei Xu, Chenguang Jiang, Yingying Yue, Suzhen Chen, Ying Chen, Dan Wang, Yonggui Yuan

{"title":"Abnormal Insula Network Characteristics in Panic Disorder.","authors":"Linlin You, Wenhao Jiang, Taipeng Sun, Yue Zhou, Gang Chen, Wei Xu, Chenguang Jiang, Yingying Yue, Suzhen Chen, Ying Chen, Dan Wang, Yonggui Yuan","doi":"10.47626/1516-4446-2023-3520","DOIUrl":"https://doi.org/10.47626/1516-4446-2023-3520","url":null,"abstract":"Background: Panic disorder (PD) is a common disabling condition characterized by recurrent panic attacks. Emotional and behavioral impairments are associated with functional connectivity (FC) and network abnormalities. We used the whole brain FC, modular networks, and graph-theory analysis to investigate extensive network profiles in PD.Method: The functional MRI data from 82 PD and 97 controls were included. Intrinsic FC between each pair of 160 regions, 6 intra-networks, and 15 inter-networks were analyzed. The topological properties were explored.Results: PD patients showed altered FCs within the right insula, between frontal cortex-posterior cingulate cortex (PCC), frontal cortex-cerebellum, and PCC-occipital cortex (corrected P values < 0.001). Lower connections within the Sensorimotor Network (SMN) and SMN-Occipital Network (OCN) were detected (P values < 0.05). Various decreased global and local network features were found in PD (P values < 0.05). In addition, significant correlations were found between PD symptoms and nodal efficiency (Ne) in the insula (r = -0.273, P = 0.016), and the FC of the intra-insula (r = -0.226, P = 0.041).Conclusions: PD patients present with abnormal functional brain networks, especially the decreased FC and Ne within insula, suggesting that dysfunction of information integration plays an important role in PD.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141318179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0