Elsa S Lima, Camila P Perico, Bruno T L Nichio, Guilherme T Linhares, Amora Schwanka, Reginaldo D da Silveira, Dieval Guizelini, Luiz A P Neves, Roberto T Raittz, Jeroniza N Marchaukoski
{"title":"Emotional recognition technologies applied to health: Review and challenges.","authors":"Elsa S Lima, Camila P Perico, Bruno T L Nichio, Guilherme T Linhares, Amora Schwanka, Reginaldo D da Silveira, Dieval Guizelini, Luiz A P Neves, Roberto T Raittz, Jeroniza N Marchaukoski","doi":"10.47626/1516-4446-2024-3963","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3963","url":null,"abstract":"<p><p>Emotions affect health and health affects emotions. Emotions can help in the prevention, diagnosis, and treatment of many diseases when properly recognized and interpreted. Affective computing emerges to detect one or more signals associated with human emotions. Research into the use of emotion recognition in healthcare is scarce, therefore it is crucial to explore the reasons behind this phenomenon and identify neglected methods with potential for human health. We review methods and technologies used in emotion recognition and their applications in healthcare, highlighting methods not discussed in previous reviews of the field, including electroencephalogram and electrocardiogram, thermal camera, bracelet, skin conductance, and audio. A metric based on reproducibility and population was established to assess the review articles' quality. We surveyed and analyzed studies with tools of affective computing applied to health, based on the metrics established, to qualify and identify the challenges of the area. Our study reveal that there are challenges to be overcome in detecting and recognising human emotions, related to sample size and low quality reproducibility. We list and discuss the main current challenges, perspectives and solutions to overcome the challenges, focusing on investigating the application of affective technologies in healthcare and establishing a gold standard.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mustafa Nogay Coşkun, Müge Topcuoğlu, Betül Keskin, Ali Erdoğan, Özge Doğanavşargil-Baysal
{"title":"Second to Fourth Digit Ratio (2D:4D) and Cognitive Functioning in Bipolar Disorder.","authors":"Mustafa Nogay Coşkun, Müge Topcuoğlu, Betül Keskin, Ali Erdoğan, Özge Doğanavşargil-Baysal","doi":"10.47626/1516-4446-2024-4025","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-4025","url":null,"abstract":"<p><strong>Introduction: </strong>Bipolar Disorder(BD) involves complex mood, neuropsychological, immunological, and physiological changes, with cognitive impairments persisting even during remission.Our study aimed to investigate the relationship between the second-to-fourth digit ratio(2D:4D) and cognitive functions in BD patients.</p><p><strong>Methods: </strong>Our cross-sectional study, which included forty-seven BD patients in remission for at least six months and forty-seven healthy volunteers, was designed to thoroughly understand the relationship between the 2D:4D and cognitive functions in BD.All participants were administered Stroop Test(ST), Wisconsin Card Sorting Test(WCST), and Trail Making Test A and B forms(TMT-A/B). The same researcher measured the 2D:4D ratio using a digital caliper, ensuring consistency and accuracy.</p><p><strong>Results: </strong>The left 2D:4D ratio was significantly higher in the patient group than healthy controls. Additionally, there was a statistically significant difference in ST, WCST, and TMT-A/B scores between the two groups, with the BD group scoring higher and being more unsuccessful.We also observed a weak negative correlation between the completion time of the TMT A form and the right-hand 2D:4D finger ratios in the BD group.</p><p><strong>Conclusion: </strong>The findings of our study carry significant implications.They reveal a marked difference in the 2D:4D of patients compared to healthy controls and a decline in the cognitive functions of patients even during remission.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Walter Santos Gonçalves, Carlos Eduardo F Moraes, Rosely Sichieri, Phillipa Hay, Jose Carlos Appolinario
{"title":"Suicidal ideation and medical comorbidity: a hidden problem.","authors":"Walter Santos Gonçalves, Carlos Eduardo F Moraes, Rosely Sichieri, Phillipa Hay, Jose Carlos Appolinario","doi":"10.47626/1516-4446-2025-4188","DOIUrl":"https://doi.org/10.47626/1516-4446-2025-4188","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clarice Sandi Madruga, Katia Isicawa de Sousa Barreto, Martha Canfield, Guilherme Godoy, Danilo Silveira Seabra, Ronaldo R Laranjeira, Quirino Cordeiro
{"title":"Missed opportunities to prevent the influx of newcomers into open drug scenes in Brazil.","authors":"Clarice Sandi Madruga, Katia Isicawa de Sousa Barreto, Martha Canfield, Guilherme Godoy, Danilo Silveira Seabra, Ronaldo R Laranjeira, Quirino Cordeiro","doi":"10.47626/1516-4446-2024-4087","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-4087","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unraveling Disordered Eating: A Call for Early Intervention and Action.","authors":"Stella Nasser, Thiago Fidalgo","doi":"10.47626/1516-4446-2025-4210","DOIUrl":"https://doi.org/10.47626/1516-4446-2025-4210","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniela Benzano Bumaguin, Joana Corrêa de Magalhães Narvaez, Jaqueline B Schuch, Deborah Daitschman, Sergio Kato, Lisia von Diemen, Felix H P Kessler
{"title":"Parental pattern, childhood trauma, and impulsivity contribute to the severity of crack cocaine addiction: a cluster analysis.","authors":"Daniela Benzano Bumaguin, Joana Corrêa de Magalhães Narvaez, Jaqueline B Schuch, Deborah Daitschman, Sergio Kato, Lisia von Diemen, Felix H P Kessler","doi":"10.47626/1516-4446-2024-3645","DOIUrl":"10.47626/1516-4446-2024-3645","url":null,"abstract":"<p><strong>Objective: </strong>To determine severity clusters (groups) of substance use in crack cocaine users by the severity scores of the sixth version of the Addiction Severity Index (ASI-6) and compare the groups detected in relation to risk factors as parental styles, childhood maltreatment, and impulsivity.</p><p><strong>Methods: </strong>A cross-sectional study was conducted with 531 male adults with Substance Use Disorder, admitted to a hospital treatment unit for addiction in Southern Brazil. In order to detect more homogeneous groups of individuals, the approach used involves the K-means clustering using ASI-6 scores to create clusters or groups of individuals with similar severity in different areas. Parenting styles were assessed using the Measure of Parental Style, childhood trauma was assessed using the Childhood Trauma Questionnaire, and the patients' impulsivity was measured using the Barratt Impulsivity Scale 11. Poisson Regression was used for association analysis.</p><p><strong>Results: </strong>Two distinct clusters (groups) were identified, which differed significantly across all composite scores (p<0.001). These associations were further confirmed through Poisson Regression analysis. The more severe cluster showed significantly higher scores for maternal abuse (p=0.026), sexual abuse (p=0.003), motor impulsivity (p=0.014) and unplanned above the 75th Percentile (p=0.032) compared to the less severe group. Other parenting styles, types of trauma and impulsivity were not significant different between the groups.</p><p><strong>Conclusions: </strong>The division into severity clusters contributes to the proposition of more targeted treatments. More research focusing on outpatients would be important to reinforce the impact on preventing early life factors and treating impulsivity.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Potential Adverse Events of Fluoxetine: A Real-world Study Based on FAERS Database.","authors":"Xuezheng Gao, Xiangjun Zhou, Zhiqiang Du, Qin Zhou, Ying Jiang, Haohao Zhu","doi":"10.47626/1516-4446-2024-3879","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3879","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to mine and analyze adverse event signals of fluoxetine using the FAERS database.</p><p><strong>Methods: </strong>This study focused on suspected drug adverse reaction reports from the first quarter of 2004 to the second quarter of 2023, with fluoxetine as the primary suspected drug. Four signal mining and analysis methods were employed to comprehensively assess adverse event signals.</p><p><strong>Results: </strong>A total of 19,932,732 reports were collected, of which 22,884 were primarily suspected of fluoxetine. Through analysis, 862 PT signals involving 27 SOCs were identified. Among the reported patients, female patients (58.81%) reported a higher proportion than males (26.84%), and the age group of 18 to 45 held the largest percentage. Adverse event signal strength related to pregnancy and neonatal conditions was notable, including Foetal exposure during pregnancy, Exposure during pregnancy, and neonatal health-related adverse events showed higher signal strength, such as Atrial septal defect, Premature baby, Ventricular septal defect, and Maternal drugs affecting the fetus.</p><p><strong>Conclusion: </strong>Although Fluoxetine has been extensively approved and applied, its use in pregnant and planning-to-conceive women should be approached with caution.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kelly Acosta Gallardo, Nestor Andrades, Trino Baptista, Jose de Leon, Carlos De las Cuevas, Daniel Jose Salazar Juarez
{"title":"A case of recurrent priapism during prolonged clozapine administration","authors":"Kelly Acosta Gallardo, Nestor Andrades, Trino Baptista, Jose de Leon, Carlos De las Cuevas, Daniel Jose Salazar Juarez","doi":"10.47626/1516-4446-2024-4053","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-4053","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"It is unlikely that major depression severity correlates with white matter lesion volume.","authors":"Josef Finsterer, Joao Gama Marques","doi":"10.47626/1516-4446-2025-4121","DOIUrl":"https://doi.org/10.47626/1516-4446-2025-4121","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedro Henrique Rodrigues da Silva, Marie-Anne Vanderhasselt, Giuseppina Pilloni, Leigh Charvet, Frank Padberg, Marom Bikson, André R Brunoni, Lais B Razza
{"title":"Challenges and future directions of Transcranial Direct Current Stimulation for Depression: insights from a systematic review and meta-analysis.","authors":"Pedro Henrique Rodrigues da Silva, Marie-Anne Vanderhasselt, Giuseppina Pilloni, Leigh Charvet, Frank Padberg, Marom Bikson, André R Brunoni, Lais B Razza","doi":"10.47626/1516-4446-2024-3989","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3989","url":null,"abstract":"<p><p>Depression is a common and debilitating disorder affecting millions. First-line treatments fail to achieve remission in about one-third of patients, highlighting a critical treatment need. Transcranial direct current stimulation (tDCS) has emerged as a novel treatment for depression. Therefore, the aim of this review was to provide a comprehensive overview of the last decade of tDCS trials for depression and propose future research directions. To compile studies of the past decade, we conducted a systematic review and meta-analysis of randomized clinical trials (RCTs) of tDCS for depression. A total of 21 RCTs were included, presenting a moderate effect for active tDCS compared to placebo. We also provided a description of study designs, stimulation parameters, and patients' characteristics. Following, we proposed possible strategies to enhance clinical effectiveness and reduce variability in results, including 1) optimization/personalization of tDCS via spatial and temporal target localization; 2) optimized methodological strategies, including home-based, accelerated tDCS protocols and novel trial designs; and 3) investigate patient profile to identify features that can predict treatment response. In conclusion, tDCS holds promise as a treatment for depression, but variability in trial parameters and outcomes underscores the need for its further optimization. Refining and standardizing protocols may enhance its effectiveness.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}