Vitor A Petrilli-Mazon, Marcos O Carvalho-Alves, Eurípedes Constantino Miguel, Felipe Corchs, Mariana Curi, Yuan-Pang Wang
{"title":"Item-wise validity study of the Impact of Event Scale - Revised (IES-R): self-reported reactions of hospital personnel exposed to a stressful workplace.","authors":"Vitor A Petrilli-Mazon, Marcos O Carvalho-Alves, Eurípedes Constantino Miguel, Felipe Corchs, Mariana Curi, Yuan-Pang Wang","doi":"10.47626/1516-4446-2024-3882","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3882","url":null,"abstract":"<p><strong>Objective: </strong>Recent studies have revealed a heterogeneous prevalence and presentation of PTSD across countries. It is crucial to assess the methodological and item-level measurement factors that contribute to variations in mental disorder rates across cultures. This study aimed to investigate the traumatic experiences of hospital workers by employing item analysis of the Impact of Event Scale-Revised (IES-R).</p><p><strong>Methods: </strong>Data were collected from 1,000 employees of a large hospital during the COVID-19 pandemic and were further subjected to item response theory (IRT) analysis with respect to the discrimination (a) and difficulty (b) parameters of the item pool.</p><p><strong>Results: </strong>Our results demonstrated that the IES-R items had a good discriminative ability (a) and covered a range of distress severity (b) associated with traumatic experiences. The IES-R was found to be a reliable and informative instrument for assessing individuals with moderate to severe trauma-related distress across the spectrum of traumatic symptoms. In particular, items #10 (\"jumpy or easily startled\") and #6 (\" thought about it when didn't mean to\"), reflecting the PTSD domains of hyperarousal and intrusion, excelled in discriminating between different levels of traumatic distress. Conversely, items related to avoidance and sleep disturbance showed diminished discriminative ability.</p><p><strong>Conclusions: </strong>The item analysis of the IES-R may be used to assess trauma symptoms in the context of a traumatic exposure, thereby identifying the most discriminative and informative items of the PTSD measure in our context. Our findings may refine the IES-R and facilitate the development of a more effective scale with optimized item parameters.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Virtual reality, social intelligence, mirror neurons and bipolar spectrum a new perspective.","authors":"Mauro G Carta, Antonio E Nardi","doi":"10.47626/1516-4446-2024-3901","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3901","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alessandra Faggion Mocellin, Clara de Oliveira Lapa, Clarissa Severino Gama
{"title":"A rare event of late agranulocytosis during clozapine use in schizophrenia and the importance of monitoring vitamin B12 levels in patients with severe psychiatric conditions: a case report.","authors":"Alessandra Faggion Mocellin, Clara de Oliveira Lapa, Clarissa Severino Gama","doi":"10.47626/1516-4446-2024-3852","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3852","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142648452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fabiana Araújo Figueiredo da Mata, Ari Alex Ramos, Laiss Bertola, Thais Suarez, Cleusa Pinheiro Ferri, Haliton Alves de Oliveira Júnior
{"title":"Costs of dementia in Brazil.","authors":"Fabiana Araújo Figueiredo da Mata, Ari Alex Ramos, Laiss Bertola, Thais Suarez, Cleusa Pinheiro Ferri, Haliton Alves de Oliveira Júnior","doi":"10.47626/1516-4446-2024-3611","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3611","url":null,"abstract":"<p><strong>Background: </strong>Given the increasing number of people with dementia in Brazil, there is an urgency for health and social systems to plan strategies to meet the needs of this population and their families. Therefore, research on dementia costs is essential. This study estimated direct and indirect costs related to dementia in Brazil.</p><p><strong>Methods: </strong>We employed the cost of illness study methodology to estimate dementia-related costs. Moreover, we used household interview data from the ReNaDe project and public, free-of-charge national databases to collect service use and values information. The societal and the SUS (Brazilian Universal Health System) perspectives were adopted.</p><p><strong>Results: </strong>The monthly cost of dementia per individual increases with the syndrome's progression from US$ 843.04 in the initial stage to US$ 1,317.81 in the intermediate stage, peaking at US$ 1,576.15 in the advanced stage. Indirect costs constitute at least 73% of total expenses. When considering the costs for Brazil, it is in the intermediate stage of dementia that the country's total expenses are the highest.</p><p><strong>Conclusions: </strong>Family caregivers shoulder at least 73% of the health-related costs of dementia in Brazil, highlighting the need to improve and create supporting strategies for people with dementia and their families.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142648416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adventures of Psychiatry in a General Hospital: A tale of C-L psychiatry origins and resistance in Brazil.","authors":"Juliano Victor Luna, João Alberto Carvalho","doi":"10.47626/1516-4446-2024-3854","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3854","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Signal Mining and Risk Analysis of Olanzapine Adverse Events in the FAERS Database.","authors":"Aiguo Dong, Lingyi Shi, Zhiqiang Du, Qin Zhou, Ying Jiang, Haohao Zhu, Anqing Zhu","doi":"10.47626/1516-4446-2024-3880","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3880","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to assess the safety profile of Olanzapine by analyzing adverse events (AEs) reported in the FAERS database, particularly focusing on newly identified risks.</p><p><strong>Method: </strong>The study involved adverse events (AEs) related to Olanzapine from January 1, 2004, to June 30, 2023. Four signal mining methods were used for a comprehensive analysis of the frequency and strength of AEs, including ROR, PRR, BCPNN, and EBGM.</p><p><strong>Results: </strong>A total of 43,664 reports with Olanzapine as the primary suspect drug were collected. 776 PT signals involving 27 SOCs were identified. The main affected groups were females and the age group of 18 to 45 years. Psychiatric disorders and Nervous system disorders were the most common adverse reactions. Moreover, the analysis revealed some adverse reactions not recorded in the manual, including cardiovascular risks like Pancreatitis, Chylomicron increased, Hyperchylomicronaemia, and Myocardial reperfusion injury, as well as rare but serious adverse reactions like Neuroleptic malignant syndrome and Anosognosia.</p><p><strong>Conclusion: </strong>This study identified new cardiovascular risks associated with Olanzapine, including pancreatitis and myocardial reperfusion injury, which require further investigation.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142648420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana Troesch, Sarah Prates, Stella Sarmento, Thiago Cerqueira-Silva, Gabriela Léda-Rêgo, Caroline Dallalana, Juliana S Casqueiro, Paula Studart-Bottó, Ângela Miranda-Scippa
{"title":"Satisfactory Levels of Functionality and Quality of Life in Caregivers of Patients with Bipolar Disorder: Is this Possible?","authors":"Mariana Troesch, Sarah Prates, Stella Sarmento, Thiago Cerqueira-Silva, Gabriela Léda-Rêgo, Caroline Dallalana, Juliana S Casqueiro, Paula Studart-Bottó, Ângela Miranda-Scippa","doi":"10.47626/1516-4446-2024-3866","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3866","url":null,"abstract":"<p><strong>Objectives: </strong>To measure the levels of functionality and QoL of caregivers of patients with BD, investigating the association between them, as well as the relationship with clinical and sociodemographic data of these caregivers.</p><p><strong>Method: </strong>A cross-sectional study was conducted between 2020 and 2022 with caregivers of patients with BD treated in an outpatient clinic of a university hospital. The following instruments were applied: Clinical and sociodemographic questionnaire, WHODAS 2.0, SF-36, MINI-PLUS, and SCID II.</p><p><strong>Results: </strong>The median score on WHODAS 2.0 was less than 20. In SF-36, the medians found in its domains were above 60. Those who demonstrated greater functional impairment had lower QoL. Being younger, being a parent, having non-psychiatric clinical conditions, and having mental disorders were associated with worse QoL and lower functionality.</p><p><strong>Conclusion: </strong>The results obtained indicate less functional impairment and a better perception of QoL when compared to literature data, demonstrating that there is a subgroup of caregivers who perform their caregiving role without significant compromise in these health aspects. Exploring other factors associated with functionality and QoL, such as resilience, the presence of psychological support, or others, may allow for better targeting of public health interventions, optimizing comprehensive bidirectional care for patients and caregivers.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adriana Munhoz Carneiro, Fernando Dos Santos Fernandes, Ricardo Alberto Moreno, Doris Hupfeld Moreno
{"title":"Are we correctly diagnosing and screening bipolar depression?","authors":"Adriana Munhoz Carneiro, Fernando Dos Santos Fernandes, Ricardo Alberto Moreno, Doris Hupfeld Moreno","doi":"10.47626/1516-4446-2024-3808","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3808","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Manipulating levels of uncertainty in a decision making task for obsessive-compulsive disorder.","authors":"Uma Maheswari Ganesh, Lavanya Sharma, Himani Kashyap, Shyam Sundar Arumugham, Janardhan Reddy","doi":"10.47626/1516-4446-2023-3432","DOIUrl":"https://doi.org/10.47626/1516-4446-2023-3432","url":null,"abstract":"<p><strong>Objective: </strong>The study aims to investigate whether manipulating levels of uncertainty would influence performance in a decision-making task in obsessive-compulsive disorder (OCD).</p><p><strong>Methods: </strong>This case-control study compares the performance in beads task (measuring reflection/decisional impulsivity) performance and trait impulsivity (Short Urgency-Premeditation-Perseverance-Sensation Seeking-Positive Urgency (UPPS-P)) in patients with OCD (n=65) and non-clinical controls (n=45). Mann Whitney U test was carried out to assess between-group differences.</p><p><strong>Results: </strong>The OCD group had significantly lesser draws to decision (U=1845 , p=.019) and subjective decisional-certainty (U=1518, p=0.00) in the low-uncertainty (85:15) condition , higher scores of negative urgency (U= 2163, p=<0.001) and lower scores on sensation-seeking (U= 907.5, p=.001) in the UPPS-P. However, the comparison of beads task performance does not survive correction for multiple comparisons.</p><p><strong>Conclusion: </strong>Patients with OCD engage in impulsive decision-making in the lower-uncertainty condition in comparison to healthy controls, despite low subjective certainty of the decision. They also had increased scores on the trait impulsivity factor of negative urgency. Future studies may explore the relationship between trait impulsivity as well as the contributions of symptom severity, anxiety and decisional certainty to impulsivity in OCD.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seeking psychiatric emergency care by individuals who died by suicide in Fortaleza in 2022.","authors":"Ana Carolina Asfor, Matias Melo","doi":"10.47626/1516-4446-2024-3635","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3635","url":null,"abstract":"<p><strong>Objectives: </strong>Suicide represents 1% of all deaths in the world. It's more prevalent in underdeveloped countries. Suicide mortality in Brazil has been growing in recent years. We Evaluated whether patients who committed suicide in Fortaleza sought the only psychiatric emergency service in the State before the act during the year 2022.</p><p><strong>Methods: </strong>Retrospective cross-sectional study with data from electronic psychiatric emergency records and expert reports from the state forensic expertise service.</p><p><strong>Results: </strong>292 deaths were identified, which represents almost 2% of mortality in Fortaleza this year, 25% of which were female and 74.6% were male. Only 2.7% of individuals who committed suicide within this period requested a psychiatric emergency evaluation in the 3 months before the death. Among these individuals, 75% mentioned suicidal ideation. Furthermore, 70% of deaths were due to hanging.</p><p><strong>Conclusions: </strong>The study found that the majority of patients who committed suicide in Fortaleza in 2022 did not seek the only psychiatric emergency service before the event, more studies are needed to investigate the causes of this behavior.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}