Revista Brasileira de Psiquiatria最新文献

Can Socioeconomic Status Moderate the Effect of a Conflictive Family Environment on Brain Structure and Externalising-Internalising Behaviour in Children and Adolescents? 社会经济地位能否调节冲突家庭环境对儿童和青少年大脑结构和外化-内化行为的影响？

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-05-17 DOI: 10.47626/1516-4446-2025-4195

Elizabeth Trejos-Castillo, Ann Mastergeorge, Hugo Cogo-Moreira, Vinicius Oliveira Santana, André Zugman, Célia Maria de Araújo, Pedro Mario Pan, Felipe Picon, Luis Augusto Paim Rohde, Andrea P Jackowski

{"title":"Can Socioeconomic Status Moderate the Effect of a Conflictive Family Environment on Brain Structure and Externalising-Internalising Behaviour in Children and Adolescents?","authors":"Elizabeth Trejos-Castillo, Ann Mastergeorge, Hugo Cogo-Moreira, Vinicius Oliveira Santana, André Zugman, Célia Maria de Araújo, Pedro Mario Pan, Felipe Picon, Luis Augusto Paim Rohde, Andrea P Jackowski","doi":"10.47626/1516-4446-2025-4195","DOIUrl":"https://doi.org/10.47626/1516-4446-2025-4195","url":null,"abstract":"Objective: This study examines the effects of socioeconomic status (SES) as a possible moderator of the effects of family conflict on externalising and internalising behaviours, and hippocampal and amygdala volumes.Methods: A longitudinal complete-case analysis of 714 children and adolescents (mean age: 11.2 years; 46.2% females) was conducted using data from the Brazilian High-Risk Cohort Study for Psychiatric Disorders in Childhood (BHRC). At baseline, parents/guardians completed the Family Environment Scale and the Brazilian SES Questionnaire. Three years after baseline, the same participants underwent brain magnetic resonance imaging, and the Child Behaviour Checklist (CBCL) was administered. Automated segmentation of the amygdala and hippocampus was performed using FreeSurfer v.5.1 software.Results: Family conflict at baseline predicted internalising and externalising behaviours at follow-up. Evidence regarding the effects of family conflict and SES on brain structure and the moderating effects of family conflict on psychopathology and brain outcomes conditioned on SES was lacking.Conclusion: These results are consistent with emerging evidence that family conflict is a risk factor for externalising and internalising youth behaviour. These findings warrant further attention, focusing on prevention and intervention efforts and social policy development.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obesity, Stigmatization, and Mental Health: The Imperative of a Psychosocial and Legal Approach in Brazil. 肥胖、污名化和心理健康：巴西社会心理和法律途径的必要性。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-05-17 DOI: 10.47626/1516-4446-2025-4259

Gabriela Rocha Dos Santos, Brunna Boaventura, Daniel Prates Baldez, Natasha Kim de Oliveira da Fonseca, Gabrielle Terezinha Fopa, Lucas Maynard Lovato, Rodolfo Furlan Damiano, Gisele Gus Manfro

引用次数: 0

Emotional recognition technologies applied to health: Review and challenges. 情感识别技术在健康中的应用：回顾与挑战。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-04-29 DOI: 10.47626/1516-4446-2024-3963

Elsa S Lima, Camila P Perico, Bruno T L Nichio, Guilherme T Linhares, Amora Schwanka, Reginaldo D da Silveira, Dieval Guizelini, Luiz A P Neves, Roberto T Raittz, Jeroniza N Marchaukoski

{"title":"Emotional recognition technologies applied to health: Review and challenges.","authors":"Elsa S Lima, Camila P Perico, Bruno T L Nichio, Guilherme T Linhares, Amora Schwanka, Reginaldo D da Silveira, Dieval Guizelini, Luiz A P Neves, Roberto T Raittz, Jeroniza N Marchaukoski","doi":"10.47626/1516-4446-2024-3963","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3963","url":null,"abstract":"Emotions affect health and health affects emotions. Emotions can help in the prevention, diagnosis, and treatment of many diseases when properly recognized and interpreted. Affective computing emerges to detect one or more signals associated with human emotions. Research into the use of emotion recognition in healthcare is scarce, therefore it is crucial to explore the reasons behind this phenomenon and identify neglected methods with potential for human health. We review methods and technologies used in emotion recognition and their applications in healthcare, highlighting methods not discussed in previous reviews of the field, including electroencephalogram and electrocardiogram, thermal camera, bracelet, skin conductance, and audio. A metric based on reproducibility and population was established to assess the review articles' quality. We surveyed and analyzed studies with tools of affective computing applied to health, based on the metrics established, to qualify and identify the challenges of the area. Our study reveal that there are challenges to be overcome in detecting and recognising human emotions, related to sample size and low quality reproducibility. We list and discuss the main current challenges, perspectives and solutions to overcome the challenges, focusing on investigating the application of affective technologies in healthcare and establishing a gold standard.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Missed opportunities to prevent the influx of newcomers into open drug scenes in Brazil. 错过了阻止新来者涌入巴西公开毒品场所的机会。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-04-27 DOI: 10.47626/1516-4446-2024-4087

Clarice Sandi Madruga, Katia Isicawa de Sousa Barreto, Martha Canfield, Guilherme Godoy, Danilo Silveira Seabra, Ronaldo R Laranjeira, Quirino Cordeiro

引用次数: 0

Parental pattern, childhood trauma, and impulsivity contribute to the severity of crack cocaine addiction: a cluster analysis. 父母模式、童年创伤和冲动对快克可卡因成瘾的严重程度有影响：聚类分析。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-03-16 DOI: 10.47626/1516-4446-2024-3645

Daniela Benzano Bumaguin, Joana Corrêa de Magalhães Narvaez, Jaqueline B Schuch, Deborah Daitschman, Sergio Kato, Lisia von Diemen, Felix H P Kessler

{"title":"Parental pattern, childhood trauma, and impulsivity contribute to the severity of crack cocaine addiction: a cluster analysis.","authors":"Daniela Benzano Bumaguin, Joana Corrêa de Magalhães Narvaez, Jaqueline B Schuch, Deborah Daitschman, Sergio Kato, Lisia von Diemen, Felix H P Kessler","doi":"10.47626/1516-4446-2024-3645","DOIUrl":"10.47626/1516-4446-2024-3645","url":null,"abstract":"Objective: To determine severity clusters (groups) of substance use in crack cocaine users by the severity scores of the sixth version of the Addiction Severity Index (ASI-6) and compare the groups detected in relation to risk factors as parental styles, childhood maltreatment, and impulsivity.Methods: A cross-sectional study was conducted with 531 male adults with Substance Use Disorder, admitted to a hospital treatment unit for addiction in Southern Brazil. In order to detect more homogeneous groups of individuals, the approach used involves the K-means clustering using ASI-6 scores to create clusters or groups of individuals with similar severity in different areas. Parenting styles were assessed using the Measure of Parental Style, childhood trauma was assessed using the Childhood Trauma Questionnaire, and the patients' impulsivity was measured using the Barratt Impulsivity Scale 11. Poisson Regression was used for association analysis.Results: Two distinct clusters (groups) were identified, which differed significantly across all composite scores (p<0.001). These associations were further confirmed through Poisson Regression analysis. The more severe cluster showed significantly higher scores for maternal abuse (p=0.026), sexual abuse (p=0.003), motor impulsivity (p=0.014) and unplanned above the 75th Percentile (p=0.032) compared to the less severe group. Other parenting styles, types of trauma and impulsivity were not significant different between the groups.Conclusions: The division into severity clusters contributes to the proposition of more targeted treatments. More research focusing on outpatients would be important to reinforce the impact on preventing early life factors and treating impulsivity.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cannabis use patterns and different phenotypes in relation to other drugs use: latent class analyses from the Sao Paulo Megacity Mental Health Survey. 大麻使用模式和与其他药物使用相关的不同表型：来自圣保罗大城市心理健康调查的潜在类别分析。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-03-16 DOI: 10.47626/1516-4446-2024-3833

Camila Magalhães Silveira, João Maurício Castaldelli-Maia, Erica Rosanna Siu, Maria Carmen Viana, Yuan-Pang Wang, Laura Helena Andrade

{"title":"Cannabis use patterns and different phenotypes in relation to other drugs use: latent class analyses from the Sao Paulo Megacity Mental Health Survey.","authors":"Camila Magalhães Silveira, João Maurício Castaldelli-Maia, Erica Rosanna Siu, Maria Carmen Viana, Yuan-Pang Wang, Laura Helena Andrade","doi":"10.47626/1516-4446-2024-3833","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3833","url":null,"abstract":"Cannabis is the most widely used substance in Brazil. This study examined subtypes of individuals who use cannabis based on usage characteristics and correlates with other substance consumption and harms. Data are from the São Paulo Megacity Mental Health Survey (N = 5,037). Latent class analysis (LCA) was performed considering age of onset, use frequency , tobacco consumption, heavy episodic drinking (HED), alcohol use disorder (AUD) and substance use disorder. Logistic regression assessed class correlates, and further analysis compared socio-demographic, health and behavioral indicators. A 4-class model was optimal for 496 individuals. The 'Polydrug' class (26.2%) and the 'Former' class (5.9%) showed earlier onset and highest frequency of cannabis use, with strongest harm associations. 'Polydrug' class had higher odds of other drug use (OR=3.0), tobacco use (OR=2.5), HED (OR=1.8), and AUD (OR=1.5), compared to lighter-use groups. About 30% of those who use cannabis are at increased risk for negative outcomes, particularly those with early, frequent, and polydrug use patterns. Brazil's public health should prioritize targeted prevention on the risks associated with early and frequent cannabis, and polydrug use. Addressing this at-risk group is essential for harm reduction and a health-focused approach.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

No changes in plasma Brain-Derived Neurotrophic Factor (BDNF) levels in Treatment-Resistant Depression patients submitted to Convulsive Therapies. 接受抽搐治疗的难治性抑郁症患者血浆脑源性神经营养因子（BDNF）水平无变化。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-03-16 DOI: 10.47626/1516-4446-2024-3983

Leonardo Afonso Dos Santos, Eric Cretaz, Helena Bellini, Adriana Munhoz Carneiro, José Gallucci-Neto, Leda Leme Tallib, André Russowsky Brunoni

{"title":"No changes in plasma Brain-Derived Neurotrophic Factor (BDNF) levels in Treatment-Resistant Depression patients submitted to Convulsive Therapies.","authors":"Leonardo Afonso Dos Santos, Eric Cretaz, Helena Bellini, Adriana Munhoz Carneiro, José Gallucci-Neto, Leda Leme Tallib, André Russowsky Brunoni","doi":"10.47626/1516-4446-2024-3983","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3983","url":null,"abstract":"Background: Convulsive therapies are often effective for Treatment-Resistant Depression (TRD), although their mechanisms of action are unclear. Increases in Brain-Derived Neurotrophic Factor (BDNF) levels are observed after Electroconvulsive Therapy (ECT), but more recent evidence calls this claim into question. Moreover, Magnetic Seizure Therapy (MST), a new convulsive technique, has not yet been studied regarding possible neurotrophic modulation.Methods: We performed plasma BDNF measures before and throughout treatment of adult patients (18 to 65 years old) diagnosed with TRD and submitted to treatment with convulsive therapy (ECT or MST) in the arms of the EMCODE project.Results: We enrolled 31 participants (mean age = 38.4 years, SD = 11.88), 14 (45.16%) were submitted to ECT and 17 (54.84%) to MST. Notable improvements in depressive symptoms were observed in both groups, with no significant difference between them (p = 0.1046). Meanwhile, no significant changes in BDNF plasma levels were observed for any technique, pre and post-treatment (MD = -93.01 pg/ml, 95% CI -545.88 to 359.86), or over time (Coefficient = -67.95, SE = 37.75, p = 0.072).Conclusion: The findings suggested no significant changes in plasma BDNF following convulsive therapies, challenging the notion of BDNF as a biomarker for treatment-resistant depression.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subjective Sleep Quality and Its Subcomponents Among Homeless Individuals in São Paulo. 圣保罗无家可归者的主观睡眠质量及其子成分。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-16 DOI: 10.47626/1516-4446-2024-4078

Rafael Eduardo Benavides Gélvez, Debora Cristina Hipolide, Julia Ribeiro da Silva Vallim, Juliana Garcia Cespedes, Anderson da Silva Rosa

{"title":"Subjective Sleep Quality and Its Subcomponents Among Homeless Individuals in São Paulo.","authors":"Rafael Eduardo Benavides Gélvez, Debora Cristina Hipolide, Julia Ribeiro da Silva Vallim, Juliana Garcia Cespedes, Anderson da Silva Rosa","doi":"10.47626/1516-4446-2024-4078","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-4078","url":null,"abstract":"Objective: Sleep quality is essential for health, with sleep deprivation linked to physical and mental issues. Homeless populations face additional sleep challenges, yet this topic remains underexplored. This study assessed sleep quality among homeless individuals in São Paulo, Brazil, considering demographics and substance use.Methods: A psychiatrist conducted interviews to collect demographic and substance use data assessing sleep quality using the Pittsburgh Sleep Quality Index (PSQI). A Generalized Linear Model analyzed PSQI scores, considering sleeping location, gender, substance use, and interactions as fixed factors, with homelessness duration as a covariate. The sample comprised 177 participants (22% female, 7 transgenders; mean age: 42.8 ± 11.4 years), with an average homelessness duration of 10.5 ± 8.4 years (range: 1-40). Among them, 33% slept in shelters, 83% used depressants, 83% stimulants, and 59% hallucinogens.Results: Approximately 67% reported good subjective sleep quality (mean PSQI: 4.9 ± 2.7). Depressant and stimulant use correlated with poorer sleep. Women had poorer sleep, longer sleep latency, and greater daytime dysfunction than men.Conclusions: Positive sleep quality reports may reflect adaptive expectations from prolonged adversity and substance use. The findings highlight the need for improved shelters and targeted interventions to address sleep challenges in this vulnerable population.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive changes in post-stroke depression patients undergoing treatment with transcranial direct current stimulation (tDCS): an exploratory, ancillary analysis of a randomized, sham-controlled clinical trial. 脑卒中后抑郁症患者接受经颅直流电刺激（tDCS）治疗后的认知变化：一项随机、假对照临床试验的探索性辅助分析

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-11 DOI: 10.47626/1516-4446-2024-3847

Tamires Zanão, Roberta A M P F D Mattar, Bianca S Pinto, Janaina Oliveira, Renata R Vaughan, Isabela M Benseñor, Alessandra Goulart, André R Brunoni, Leandro Valiengo

{"title":"Cognitive changes in post-stroke depression patients undergoing treatment with transcranial direct current stimulation (tDCS): an exploratory, ancillary analysis of a randomized, sham-controlled clinical trial.","authors":"Tamires Zanão, Roberta A M P F D Mattar, Bianca S Pinto, Janaina Oliveira, Renata R Vaughan, Isabela M Benseñor, Alessandra Goulart, André R Brunoni, Leandro Valiengo","doi":"10.47626/1516-4446-2024-3847","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3847","url":null,"abstract":"Objective: Post-stroke depression (PSD) affects approximately 40% of stroke survivors, with cognitive deficits being frequently observed. Transcranial Direct Current Stimulation (tDCS) has shown promise in improving cognitive performance in stroke patients. We explored the effects of tDCS on cognitive performance in PSD.Methods: An exploratory analysis was conducted in 48 patients from a double-blinded, sham-controlled, randomized clinical trial that investigated the effects of tDCS for treating PSD. A neuropsychological battery was applied at baseline and endpoint. We assessed three key domains: (1) Stroop effect, measured by the Stroop test components (color naming, word-reading and word-color interference); (2) processing speed, assessed using the Trail Making Test and the Digit Symbol coding test; (3) executive function, evaluated with the Digit Span test and the Frontal Assessment Battery (FAB). A Linear mixed regression models were used to evaluate changes according to groups.Results: We found that the active tDCS group worsened slightly, while the sham group improved in Executive Function for the adjusted models. Significant interactions were also found for FAB.Conclusions: We found no consistent evidence that tDCS significantly improved the cognitive domains. The bidirectional association with cognition analysis suggest that tDCS effects may vary based on depression severity and task complexity.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142966406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Higher risks of hyperopia, myopia, astigmatism, and strabismus in children with autism spectrum disorder: a nationwide, population-based cohort study. 自闭症谱系障碍儿童患远视、近视、散光和斜视的风险：一项基于全国人口的队列研究。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-01 Epub Date: 2024-09-22 DOI: 10.47626/1516-4446-2023-3515

Yi-Lung Chen, Cheng-Fang Yen, Yu-Hung Lai, Ray C Hsiao, Wei-Po Chou

{"title":"Higher risks of hyperopia, myopia, astigmatism, and strabismus in children with autism spectrum disorder: a nationwide, population-based cohort study.","authors":"Yi-Lung Chen, Cheng-Fang Yen, Yu-Hung Lai, Ray C Hsiao, Wei-Po Chou","doi":"10.47626/1516-4446-2023-3515","DOIUrl":"10.47626/1516-4446-2023-3515","url":null,"abstract":"Objective: In this population-based cohort study, we compared the risks of incident hyperopia, myopia, astigmatism, and strabismus between children with autism spectrum disorder (ASD) and those without ASD.Methods: This study included children who were born in Taiwan at any time between 2004 and 2017, using data from the Taiwan Maternal and Child Health Database (TMCHD). We included 20,688 children with ASD and 2,062,120 matched controls to estimate the risks of incident hyperopia, myopia, astigmatism, and strabismus. Cox proportional hazards regression models were conducted for risk assessment. Models were adjusted for sex, calendar year of birth, and gestational age at birth. Statistical significance was determined through adjusted hazard ratios (aHRs) and 95%CIs.Results: Children with ASD had higher risks of incident hyperopia (aHR: 1.78; 95%CI 1.70-1.86), myopia (aHR: 1.27; 95%CI 1.24-1.30), astigmatism (aHR: 1.51; 95%CI 1.46-1.56), and strabismus (aHR: 2.18; 95%CI 2.05-2.32) compared to children without ASD.Conclusion: Clinicians should screen children with ASD for potential eye conditions. Further studies are required to elucidate the mechanisms linking ASD with eye diseases. In addition, studies should explore how the type and severity of ASD symptoms influence the detection of these eye conditions.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20233515"},"PeriodicalIF":3.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0