Revista Brasileira de Psiquiatria最新文献_第10页

A rare event of late agranulocytosis during clozapine use in schizophrenia and the importance of monitoring vitamin B12 levels in patients with severe psychiatric conditions: a case report. 精神分裂症患者在使用氯氮平期间出现罕见的迟发性粒细胞减少症，以及监测重症精神病患者维生素 B12 水平的重要性：病例报告。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-01-01 Epub Date: 2024-11-17 DOI: 10.47626/1516-4446-2024-3852

Alessandra Faggion Mocellin, Clara de Oliveira Lapa, Clarissa Severino Gama

引用次数: 0

Protective factors against depression in high-risk children and adolescents: a systematic review of longitudinal studies. 高危儿童和青少年抑郁症的保护因素：纵向研究的系统回顾。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-01-01 Epub Date: 2024-04-26 DOI: 10.47626/1516-4446-2023-3363

Bárbara Tietbohl-Santos, Augusto Ossamu Shintani, Bruno Braga Montezano, Paola Biazin, Giovanna Maiolli Signori, Rafaela Pulice, Giancarlo Franceschi Dalla Vecchia, Júlio César Bebber, Lucas Noronha, Ives Cavalcante Passos

{"title":"Protective factors against depression in high-risk children and adolescents: a systematic review of longitudinal studies.","authors":"Bárbara Tietbohl-Santos, Augusto Ossamu Shintani, Bruno Braga Montezano, Paola Biazin, Giovanna Maiolli Signori, Rafaela Pulice, Giancarlo Franceschi Dalla Vecchia, Júlio César Bebber, Lucas Noronha, Ives Cavalcante Passos","doi":"10.47626/1516-4446-2023-3363","DOIUrl":"10.47626/1516-4446-2023-3363","url":null,"abstract":"Objective: From a preventive perspective, this study reviewed the literature on protective factors against depressive symptoms in high-risk children and adolescents.Methods: We conducted a thorough search of the PubMed, APA, EMCare, and Embase databases for studies published between 1946 and August 25, 2023. We included only longitudinal studies that analyzed protective factors for depressive symptoms in high-risk children or adolescents, excluding cross-sectional studies, reviews, and pre-clinical studies.Results: A total of 29 studies with 62,405 participants were analyzed and 38 protective factors were identified. Positive individual characteristics, family factors, peer relationships, school-related aspects, neighborhood characteristics, and intrinsic religiosity were associated with improved depression outcomes.Conclusion: These findings have important implications for preventive strategies in this population. Addressing protective factors can help prevent depression and enhance lifetime mental health.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20233363"},"PeriodicalIF":3.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of psychiatry in areas affected by natural disasters. 精神病学在受自然灾害影响地区的作用。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-01-01 Epub Date: 2024-06-15 DOI: 10.47626/1516-4446-2024-3752

César Augusto Trinta Weber, Antônio Geraldo da Silva

引用次数: 0

Concerns over analytical decisions in "Cat ownership and schizophrenia-related disorders and psychoticlike experiences: a systematic review and meta-analysis". 对 "养猫与精神分裂症相关障碍和类精神病体验 "中分析决定的担忧：系统综述和元分析》中的分析决定引起的关注。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-01-01 Epub Date: 2024-03-06 DOI: 10.47626/1516-4446-2024-3569

Yung Gonzaga, Igor Eckert

引用次数: 0

Manipulating levels of uncertainty in a decision-making task for obsessive compulsive disorder. 在强迫症决策任务中操纵不确定性水平。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-01-01 Epub Date: 2024-11-15 DOI: 10.47626/1516-4446-2023-3432

Uma Maheswari Ganesh, Lavanya Sharma, Himani Kashyap, Shyam Sundar Arumugham, Janardhan Reddy

{"title":"Manipulating levels of uncertainty in a decision-making task for obsessive compulsive disorder.","authors":"Uma Maheswari Ganesh, Lavanya Sharma, Himani Kashyap, Shyam Sundar Arumugham, Janardhan Reddy","doi":"10.47626/1516-4446-2023-3432","DOIUrl":"10.47626/1516-4446-2023-3432","url":null,"abstract":"Objective: We investigated whether manipulating levels of uncertainty would influence performance in a decision-making task in people with obsessive-compulsive disorder.Methods: This case-control study compares Beads Task (measuring reflection/decisional impulsivity) performance and trait impulsivity (Short Urgency-Premeditation-Perseverance-Sensation Seeking-Positive Urgency [UPPS-P] Impulsive Behavior Scale) in patients with obsessive-compulsive disorder (n = 65) and non-clinical controls (n = 45). Differences between groups were assessed with the Mann Whitney U test.Results: The obsessive-compulsive disorder group had significantly fewer draws to decision (U = 1,845, p = 0.019) and less subjective decision-certainty (U = 1,518, p = 0.00) in the low uncertainty (85:15) condition, and higher negative urgency scores (U = 2,163, p ≤ 0.001) and lower sensation-seeking scores (U = 907.5, p = 0.001) in UPPS-P. However, differences in Beads Task performance did not survive correction for multiple comparisons.Conclusion: Patients with obsessive-compulsive disorder engage in more impulsive decision-making in the lower uncertainty condition than healthy controls, despite low subjective certainty of the decision. They also had higher scores for the trait impulsivity factor of negative urgency. Future studies should explore the contribution of trait impulsivity, as well as symptom severity, anxiety, and decision-certainty, to impulsivity in obsessive-compulsive disorder.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20233432"},"PeriodicalIF":3.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychiatric features of two cases of anti-nmdar autoimmune encephalitis. 两例抗恩达尔自身免疫性脑炎患者的精神特征。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-01-01 Epub Date: 2024-01-22 DOI: 10.47626/1516-4446-2023-3430

Bárbara Ferreira Althoff, Anne Orgler Sordi, Lucas Primo de Carvalho Alves, Lisieux Elaine de Borba Telles

引用次数: 0

Vitamin D serum concentration is prospectively associated with depressive symptoms in the EpiFloripa Aging Cohort Study: a structural equation modeling approach. EpiFloripa 老龄队列研究中维生素 D 血清浓度与抑郁症状的前瞻性关联：结构方程建模方法。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-01-01 Epub Date: 2024-01-21 DOI: 10.47626/1516-4446-2023-3153

Gilciane Ceolin, Júlia Dubois Moreira, Anna Quialheiro, Antônio Augusto Moura Silva, Eleonora d'Orsi, Débora Kurrle Rieger, Elisa Brietzke

{"title":"Vitamin D serum concentration is prospectively associated with depressive symptoms in the EpiFloripa Aging Cohort Study: a structural equation modeling approach.","authors":"Gilciane Ceolin, Júlia Dubois Moreira, Anna Quialheiro, Antônio Augusto Moura Silva, Eleonora d'Orsi, Débora Kurrle Rieger, Elisa Brietzke","doi":"10.47626/1516-4446-2023-3153","DOIUrl":"10.47626/1516-4446-2023-3153","url":null,"abstract":"Objective: To evaluate the direct, indirect, and total prospective effects of serum concentrations of 25-hydroxycholecalciferol (25[OH]D) on depressive symptoms in older adults.Methods: Data from the second (2013-2015) and third (2017-2019) waves of the EpiFloripa Aging Cohort Study (= 60 years) were analyzed. Depressive symptoms were assessed with the 15-item Geriatric Depression Scale. 25(OH)D levels were measured using the microparticle chemiluminescence method. A directed acyclic graph was constructed to identify the minimum set of adjustments. Structural equation modeling analysis was used to determine the effects of 25(OH)D on depressive symptoms.Results: Data from 574 older adults (63.1% female) were analyzed. In the follow-up (n=390), 16.2% of them presented severe depressive symptoms (= 6 points). Structural equation modeling analysis revealed that 25(OH)D had a small direct negative effect (ß = -0.11, p < 0.05) and an overall negative effect (ß = -0.13; p < 0.05) on depressive symptoms in wave 3 (increased 25[OH]D led to decreased depressive symptoms). No direct or indirect effect on depressive symptoms was found in wave 2.Conclusion: Our findings indicate a prospective association between 25(OH)D and depressive symptoms, suggesting a long-term effect in older adults from southern Brazil.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20233153"},"PeriodicalIF":3.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139513567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brazilian Psychiatric Association treatment guidelines for generalized anxiety disorder: perspectives on pharmacological and psychotherapeutic approaches. 巴西精神病学协会广泛性焦虑障碍(GAD)治疗指南。药理学和心理治疗方法。视角。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-01-01 Epub Date: 2023-11-13 DOI: 10.47626/1516-4446-2023-3235

Leonardo Baldaçara, Ana Beatriz Paschoal, Aldo Felipe Pinto, Fabiano Franca Loureiro, Luiz Antonio Vesco Gaiotto Antonio, Diogo de Lacerda Veiga, Thales Marcon Almeida, Diogo Cesar Dos Santos, Leandro Fernandes Malloy-Diniz, Marcelo Feijó de Mello, Andrea Feijó de Mello, Marsal Sanches, Lucas Marques Gandarela, Márcio Antonini Bernik, Antonio E Nardi, Antônio Geraldo da Silva, Ricardo R Uchida

{"title":"Brazilian Psychiatric Association treatment guidelines for generalized anxiety disorder: perspectives on pharmacological and psychotherapeutic approaches.","authors":"Leonardo Baldaçara, Ana Beatriz Paschoal, Aldo Felipe Pinto, Fabiano Franca Loureiro, Luiz Antonio Vesco Gaiotto Antonio, Diogo de Lacerda Veiga, Thales Marcon Almeida, Diogo Cesar Dos Santos, Leandro Fernandes Malloy-Diniz, Marcelo Feijó de Mello, Andrea Feijó de Mello, Marsal Sanches, Lucas Marques Gandarela, Márcio Antonini Bernik, Antonio E Nardi, Antônio Geraldo da Silva, Ricardo R Uchida","doi":"10.47626/1516-4446-2023-3235","DOIUrl":"10.47626/1516-4446-2023-3235","url":null,"abstract":"Generalized anxiety disorder is a highly prevalent mental disorder. Previous data indicate that more than 18 million Brazilians suffer from this condition. Traditionally, generalized anxiety disorder has been considered a mild mental health disorder, despite its links to lower life expectancy, cardiovascular disease, and suicide. The aim of this article is to combine elements of systematic and critical reviews to produce a synthesis of the best evidence about generalized anxiety disorder treatment. Systematic reviews, meta-analyses, and randomized controlled trials were included. The descriptor used in the search was \"generalized anxiety disorder,\" which resulted in 4,860 articles and seven other studies, of which 59 were selected. Antidepressants and benzodiazepines were indicated, as was pregabalin, and atypical antipsychotics, such as quetiapine, have been studied. Individual cognitive behavior therapy (third wave) has proven effective. There is extensive literature on many effective treatments for generalized anxiety disorder. The present review summarizes the therapeutic possibilities, emphasizing those available in Brazil. Further studies are needed to compare other available medications, assess psychotherapies and new treatments in greater depth, as well as to assess the ideal duration of therapy.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20233235"},"PeriodicalIF":3.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11302992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92156320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adventures of psychiatry in a general hospital: a tale of C-L psychiatry origins and resistance in Brazil. 综合医院的精神病学历险记：巴西 C-L 精神病学起源与抗争的故事。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-01-01 Epub Date: 2024-11-17 DOI: 10.47626/1516-4446-2024-3854

Juliano Victor Luna, João Alberto Carvalho

引用次数: 0

The association of blood biomarkers with cerebral white matter and myelin content in bipolar disorder: a systematic review. 血液生物标志物与双相情感障碍患者脑白质和髓鞘含量的关系：系统综述。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2024-01-01 Epub Date: 2023-12-20 DOI: 10.47626/1516-4446-2023-3267

Mohammad Ali, Renata Husnudinov, Bianca Wollenhaupt-Aguiar, Benicio N Frey

{"title":"The association of blood biomarkers with cerebral white matter and myelin content in bipolar disorder: a systematic review.","authors":"Mohammad Ali, Renata Husnudinov, Bianca Wollenhaupt-Aguiar, Benicio N Frey","doi":"10.47626/1516-4446-2023-3267","DOIUrl":"10.47626/1516-4446-2023-3267","url":null,"abstract":"Objectives: Evidence from diffusion tensor imaging (DTI) and postmortem studies has demonstrated white-matter (WM) deficits in bipolar disorder (BD). Changes in peripheral blood biomarkers have also been observed; however, studies evaluating the potential relationship between brain alterations and the periphery are scarce. The objective of this systematic review is to investigate the relationship between blood-based biomarkers and WM in BD.Methods: PubMed, Embase, and PsycINFO were used to conduct literature searches. Cross-sectional or longitudinal studies reporting original data which investigated both a blood-based biomarker and WM (by neuroimaging) in BD were included.Results: Of 3,750 studies retrieved, 23 were included. Several classes of biomarkers were found to have a significant relationship with WM in BD. These included cytokines and growth factors (interleukin-8 [IL-8], tumor necrosis factor alpha [TNF-a], and insulin-like growth factor binding protein 3 [IGFBP-3]), innate immune system (natural killer cells [NK]), metabolic markers (lipid hydroperoxidase, cholesterol, triglycerides), the kynurenine (Kyn) pathway (5-hydroxyindoleacetic acid, kynurenic acid [Kyna]), and various gene polymorphisms (serotonin-transporter-linked promoter region).Conclusion: This systematic review revealed that blood-based biomarkers are associated with markers of WM deficits observed in BD. Longitudinal studies investigating the potential clinical utility of these specific biomarkers are encouraged.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":"46 ","pages":"e20233267"},"PeriodicalIF":3.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11189111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0