Revista Brasileira de Psiquiatria最新文献

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Prediction of declarative memory profile in panic disorder patients: a machine learning-based approach. 惊恐障碍患者声明性记忆谱的预测:一种基于机器学习的方法。
3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2023-11-01 Epub Date: 2023-10-25 DOI: 10.47626/1516-4446-2023-3291
Felipe Dalvi-Garcia, Laiana Azevedo Quagliato, Donald J Bearden, Antonio Egidio Nardi
{"title":"Prediction of declarative memory profile in panic disorder patients: a machine learning-based approach.","authors":"Felipe Dalvi-Garcia, Laiana Azevedo Quagliato, Donald J Bearden, Antonio Egidio Nardi","doi":"10.47626/1516-4446-2023-3291","DOIUrl":"10.47626/1516-4446-2023-3291","url":null,"abstract":"<p><strong>Objective: </strong>To develop a classification framework based on random forest (RF) modeling to outline the declarative memory profile of patients with panic disorder (PD) compared to a healthy control sample.</p><p><strong>Methods: </strong>We developed RF models to classify the declarative memory profile of PD patients in comparison to a healthy control sample using the Rey Auditory Verbal Learning Test (RAVLT). For this study, a total of 299 patients with PD living in the city of Rio de Janeiro (70.9% females, age 39.9 ± 7.3 years old) were recruited through clinician referrals or self/family referrals.</p><p><strong>Results: </strong>Our RF models successfully predicted declarative memory profiles in patients with PD based on RAVLT scores (lowest area under the curve [AUC] of 0.979, for classification; highest root mean squared percentage [RMSPE] of 17.2%, for regression) using relatively bias-free clinical data, such as sex, age, and body mass index (BMI).</p><p><strong>Conclusions: </strong>Our findings also suggested that BMI, used as a proxy for diet and exercises habits, plays an important role in declarative memory. Our framework can be extended and used as a prospective tool to classify and examine associations between clinical features and declarative memory in PD patients.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50162746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progressive multifocal leukoencephalopathy cannot be due to liver cirrhosis alone. 进行性多灶性白质脑病不能仅由肝硬化引起。
3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2023-11-01 Epub Date: 2023-10-19 DOI: 10.47626/1516-4446-2023-3375
Fulvio A Scorza, Josef Finsterer
{"title":"Progressive multifocal leukoencephalopathy cannot be due to liver cirrhosis alone.","authors":"Fulvio A Scorza, Josef Finsterer","doi":"10.47626/1516-4446-2023-3375","DOIUrl":"10.47626/1516-4446-2023-3375","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50162747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is maintenance needed for patients who responded to acute TMS therapy? 对急性 TMS 治疗有反应的患者是否需要维持治疗?
3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2023-11-01 Epub Date: 2023-09-17 DOI: 10.47626/1516-4446-2023-0052
Bashar Asir, Andrea Boscutti, João Quevedo
{"title":"Is maintenance needed for patients who responded to acute TMS therapy?","authors":"Bashar Asir, Andrea Boscutti, João Quevedo","doi":"10.47626/1516-4446-2023-0052","DOIUrl":"10.47626/1516-4446-2023-0052","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10339045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fifty years of research on cannabidiol (CBD) as an anticonvulsant: The legacy of Brazilian groups. 大麻二酚(CBD)作为抗惊厥药的50年研究:巴西团体的遗产。
3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2023-11-01 Epub Date: 2023-11-25 DOI: 10.47626/1516-4446-2023-3377
Antonio Waldo Zuardi, José Alexandre Crippa
{"title":"Fifty years of research on cannabidiol (CBD) as an anticonvulsant: The legacy of Brazilian groups.","authors":"Antonio Waldo Zuardi, José Alexandre Crippa","doi":"10.47626/1516-4446-2023-3377","DOIUrl":"10.47626/1516-4446-2023-3377","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138441139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association between maternal fears about their infant/ toddler during the COVID-19 pandemic and depression and anxiety: a birth cohort study. COVID-19大流行期间母亲对婴儿/幼儿的恐惧与母亲抑郁和焦虑轨迹的关联:一项出生队列研究
3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2023-11-01 Epub Date: 2023-11-13 DOI: 10.47626/1516-4446-2023-3306
Raquel Wermann Foschiera, Júlia Pustrelo Moro, Fabiana de Abreu Getulino, Marina Xavier Carpena, Francine Dos Santos Costa, Cauane Blumenberg, Rafaela Costa Martins, Thais Martins-Silva, Luana Patrícia Marmitt, Alejandra Goicochea, Rodrigo Meucci, Juraci Cesar, Christian Loret de Mola
{"title":"The association between maternal fears about their infant/ toddler during the COVID-19 pandemic and depression and anxiety: a birth cohort study.","authors":"Raquel Wermann Foschiera, Júlia Pustrelo Moro, Fabiana de Abreu Getulino, Marina Xavier Carpena, Francine Dos Santos Costa, Cauane Blumenberg, Rafaela Costa Martins, Thais Martins-Silva, Luana Patrícia Marmitt, Alejandra Goicochea, Rodrigo Meucci, Juraci Cesar, Christian Loret de Mola","doi":"10.47626/1516-4446-2023-3306","DOIUrl":"10.47626/1516-4446-2023-3306","url":null,"abstract":"<p><strong>Objective: </strong>To assess the association between maternal fears about their infant/toddler and depression and anxiety during the COVID-19 pandemic.</p><p><strong>Methods: </strong>In 2019, all mothers who gave birth in hospitals in Rio Grande, RS, Brazil were asked to respond to a standardized questionnaire (baseline). We followed them between May-June 2020 (first follow-up point), August-December 2020 (second follow-up point), and from October 2021 to March 2022 (third follow-up point), and asked them if they were: (1) afraid that their infant/toddler would become infected with COVID or get sick (yes/no), (2) afraid that they would contaminate their own child with COVID, and/or (3) worried about the pandemic's effects on their child's future. At baseline and at all follow-up points, we assessed depressive symptoms using the Edinburgh Postnatal Depression Scale and anxiety symptoms using the Generalized Anxiety Disorder Scale, creating symptom trajectories using group-based trajectory modelling. We used multinomial logistic regression to calculate adjusted relative risk ratios (RRR).</p><p><strong>Results: </strong>A total of 1,296 mothers participated. Worrying about the pandemic's effects on their child's future and the fear of contaminating their own child with COVID-19 increased the risk of raising depressive symptoms to a clinical level (RRR = 4.97, 95%CI 2.32-10.64 and RRR = 3.87, 95%CI 1.58-9.47, respectively) and anxiety to a moderate level (RRR = 2.91, 95%CI 1.69-5.01 and RRR = 1.86, 95%CI 1.03-3.35, respectively).</p><p><strong>Conclusion: </strong>Fear for their children increased maternal depressive and anxiety symptoms during the pandemic.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92156323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for executive function impairment in adolescence: an analysis of data from the 2004 Pelotas Birth Cohort study. 青少年执行功能障碍的危险因素:2004年Pelotas出生队列研究。
3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2023-11-01 Epub Date: 2023-11-23 DOI: 10.47626/1516-4446-2023-3277
Júlia de Souza Rodrigues, Alicia Matijasevich, Luciana Tovo-Rodrigues, Tiago N Munhoz, Iná S Santos, Maria Pastor-Valero
{"title":"Risk factors for executive function impairment in adolescence: an analysis of data from the 2004 Pelotas Birth Cohort study.","authors":"Júlia de Souza Rodrigues, Alicia Matijasevich, Luciana Tovo-Rodrigues, Tiago N Munhoz, Iná S Santos, Maria Pastor-Valero","doi":"10.47626/1516-4446-2023-3277","DOIUrl":"10.47626/1516-4446-2023-3277","url":null,"abstract":"<p><strong>Objective: </strong>To investigate risk factors associated with impaired attention-related executive functions (EFs) at age 11 and working memory at age 15.</p><p><strong>Methods: </strong>Data from participants of the population-based 2004 Pelotas Birth Cohort at ages 11 (n=3,582) and 15 (n=1,950) were analyzed. The study measured attentional control, cognitive flexibility, and selective attention using the Test of Everyday Attention for Children (TEA-Ch). Spatial working memory was assessed by the Cambridge Neuropsychological Test Automated Battery (CANTAB). Logistic regression was employed to explore the relationship between perinatal and childhood exposures and EF impairment.</p><p><strong>Results: </strong>Low maternal education had a significant negative impact on EFs. At age 11, it was associated with decreased attentional control (OR = 3.04; 95%CI 2.09-4.43), and at age 15, it was linked to impaired spatial working memory (OR = 2.21; 95%CI 1.58-3.09). Additional risk factors included low household income, black or brown maternal skin color, high parity, prematurity, low birth weight, and multiple siblings. Breastfeeding, regardless of duration, was found to be a protective factor against impaired cognitive flexibility (OR = 0.38; 95%CI 0.22-0.65).</p><p><strong>Conclusion: </strong>This study underscores the lasting impact of perinatal exposures on EF development. Policies that mitigate the negative effects of risk factors and promote EF development, especially among vulnerable populations, are needed.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138299864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brazilian Psychiatric Association guidelines on the integration of spirituality into mental health clinical practice: Part 1. Spiritual history and differential diagnosis. 巴西精神病学协会关于将灵性融入心理健康临床实践的指南:第一部分。精神病史和鉴别诊断。
IF 3.6 3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2023-11-01 Epub Date: 2023-09-17 DOI: 10.47626/1516-4446-2023-3056
Bruno Paz Mosqueiro, Marianna de Abreu Costa, André C Caribé, Fabrício H A Oliveira E Oliveira, Leandro Pizutti, Rogério R Zimpel, Leonardo Baldaçara, Antônio Geraldo da Silva, Alexander Moreira-Almeida
{"title":"Brazilian Psychiatric Association guidelines on the integration of spirituality into mental health clinical practice: Part 1. Spiritual history and differential diagnosis.","authors":"Bruno Paz Mosqueiro, Marianna de Abreu Costa, André C Caribé, Fabrício H A Oliveira E Oliveira, Leandro Pizutti, Rogério R Zimpel, Leonardo Baldaçara, Antônio Geraldo da Silva, Alexander Moreira-Almeida","doi":"10.47626/1516-4446-2023-3056","DOIUrl":"10.47626/1516-4446-2023-3056","url":null,"abstract":"<p><strong>Objectives: </strong>To present evidence-based guidelines for clinical practice regarding religiosity and spirituality in mental health care in Brazil.</p><p><strong>Methods: </strong>A systematic review was conducted to identify potentially eligible articles indexed in the PubMed, PsycINFO, SciELO, LILACS, and Cochrane databases. A summary of recommendations and their levels of evidence was produced in accordance with Oxford Centre for Evidence-Based Medicine guidelines.</p><p><strong>Results: </strong>The systematic review identified 6,609 articles, 41 of which satisfied all inclusion criteria. Taking a spiritual history was found to be an essential part of a compassionate and culturally sensitive approach to care. It represents a way of obtaining relevant information about the patient's religiosity/spirituality, potential conflicts that could impact treatment adherence, and improve patient satisfaction. Consistent evidence shows that reported perceptual experiences are unreliable for differentiating between anomalous experiences and psychopathology. Negative symptoms, cognitive and behavioral disorganization, and functional impairment are more helpful for distinguishing pathological and non-pathological anomalous experiences.</p><p><strong>Conclusion: </strong>Considering the importance of religiosity/spirituality for many patients, a spiritual history should be routinely included in mental health care. Anomalous experiences are highly prevalent, requiring a sensitive and evidence-based approach to differential diagnosis.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10339071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Professor Ellis Alindo D'Arrigo Busnello: a humanist and a scientist with a passion for psychiatry and psychopathology. A great mentor of Brazilian scientific postgraduate programs in psychiatry. 埃利斯-阿林多-达里戈-布斯内罗教授:一位对精神病学和精神病理学充满热情的人文主义者和科学家。他是巴西精神病学研究生科学项目的伟大导师。
3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2023-11-01 Epub Date: 2023-10-30 DOI: 10.47626/1516-4446-2023-3332
Flavio Kapczinski, Antonio E Nardi
{"title":"Professor Ellis Alindo D'Arrigo Busnello: a humanist and a scientist with a passion for psychiatry and psychopathology. A great mentor of Brazilian scientific postgraduate programs in psychiatry.","authors":"Flavio Kapczinski, Antonio E Nardi","doi":"10.47626/1516-4446-2023-3332","DOIUrl":"10.47626/1516-4446-2023-3332","url":null,"abstract":"","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10339072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rural-urban disparities in fruit and vegetable consumption and cognitive performance in Brazil. 巴西城乡水果和蔬菜消费差异与认知表现。
3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2023-11-01 Epub Date: 2023-11-23 DOI: 10.47626/1516-4446-2023-3316
Natalia Gomes Gonçalves, Laiss Bertola, Cleusa Pinheiro Ferri, Claudia Kimie Suemoto
{"title":"Rural-urban disparities in fruit and vegetable consumption and cognitive performance in Brazil.","authors":"Natalia Gomes Gonçalves, Laiss Bertola, Cleusa Pinheiro Ferri, Claudia Kimie Suemoto","doi":"10.47626/1516-4446-2023-3316","DOIUrl":"10.47626/1516-4446-2023-3316","url":null,"abstract":"<p><strong>Objectives: </strong>Rural residents are exposed to many risk factors for poor diet quality, such as low socioeconomic status and food insecurity. However, the differences between urban and rural residents regarding the association of fruit and vegetable consumption with cognitive performance have not been explored. The aim of this study was to investigate the association of fruit and vegetable consumption with cognitive performance in urban and rural areas in a nationally representative sample of Brazilian older adults.</p><p><strong>Methods: </strong>The sample included 9,412 adults aged 50 years or older from the Brazilian Longitudinal Study of Aging (Estudo Longitudinal da Saúde dos Idosos Brasileiros [ELSI]). The association between consumption of fruits and vegetables and cognitive performance was evaluated using linear regression.</p><p><strong>Results: </strong>In 8,158 participants (mean age 61.6 ± 9.3 years, 54% women, 44% White, and 15% from rural areas), the mean frequency of fruit and vegetable consumption was 2.0 ± 1.3 times a day. Higher intake of fruits and vegetables was associated with better memory (ß = 0.031, 95%CI 0.014-0.049), verbal fluency (ß = 0.030, 95%CI 0.004-0.056), and global cognition (ß = 0.035, 95%CI 0.015-0.055) performance in urban, but not rural residents (p for interaction = 0.036).</p><p><strong>Conclusions: </strong>Higher frequency of fruit and vegetable intake was associated with better cognitive performance in urban, but not in rural areas in Brazil.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138299865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An electric field modeling study with meta-analysis to understand the antidepressant effects of transcranial direct current stimulation (tDCS). 通过电场建模研究和荟萃分析了解经颅直流电刺激(tDCS)的抗抑郁效果。
3区 医学
Revista Brasileira de Psiquiatria Pub Date : 2023-11-01 Epub Date: 2023-07-03 DOI: 10.47626/1516-4446-2023-3116
Lais B Razza, Miles Wischnewski, Paulo Suen, Stefanie De Smet, Pedro Henrique Rodrigues da Silva, Beatriz Catoira, André R Brunoni, Marie-Anne Vanderhasselt
{"title":"An electric field modeling study with meta-analysis to understand the antidepressant effects of transcranial direct current stimulation (tDCS).","authors":"Lais B Razza, Miles Wischnewski, Paulo Suen, Stefanie De Smet, Pedro Henrique Rodrigues da Silva, Beatriz Catoira, André R Brunoni, Marie-Anne Vanderhasselt","doi":"10.47626/1516-4446-2023-3116","DOIUrl":"10.47626/1516-4446-2023-3116","url":null,"abstract":"<p><strong>Objective: </strong>Transcranial direct current stimulation (tDCS) has mixed effects for major depressive disorder (MDD) symptoms, partially owing to large inter-experimental variability in tDCS protocols and their correlated induced electric fields (E-fields). We investigated whether the E-field strength of distinct tDCS parameters was associated with antidepressant effect.</p><p><strong>Methods: </strong>A meta-analysis was performed with placebo-controlled clinical trials of tDCS enrolling MDD patients. PubMed, EMBASE, and Web of Science were searched from inception to March 10, 2023. Effect sizes of tDCS protocols were correlated with E-field simulations (SimNIBS) of brain regions of interest (bilateral dorsolateral prefrontal cortex [DLPFC] and bilateral subgenual anterior cingulate cortex [sgACC]). Moderators of tDCS responses were also investigated.</p><p><strong>Results: </strong>A total of 20 studies were included (21 datasets, 1,008 patients), using 11 distinct tDCS protocols. Results revealed a moderate effect for MDD (g = 0.41, 95%CI 0.18-0.64), while cathode position and treatment strategy were found to be moderators of response. A negative association between effect size and tDCS-induced E-field magnitude was seen, with stronger E-fields in the right frontal and medial parts of the DLPFC (targeted by the cathode) leading to smaller effects. No association was found for the left DLPFC and the bilateral sgACC. An optimized tDCS protocol is proposed.</p><p><strong>Conclusion: </strong>Our results highlight the need for a standardized tDCS protocol in MDD clinical trials.</p>","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10124202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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