Revista Brasileira de Psiquiatria最新文献_第3页

Has it come the moment for Brazilian government and society to ban the use of smartphones in schools? 现在是巴西政府和社会禁止在学校使用智能手机的时候了吗？

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-11 DOI: 10.47626/1516-4446-2024-4012

Paulo Marcos Brasi, Antônio Marcos Alvim-Soares, Maria Carolina Lobato Machado, Thales Pimenta de Figueiredo, Ana Paula Alcantara, Débora Marques de Miranda, Marco Aurélio Romano Silva

引用次数: 0

Association between methyl-CpG-binding domain protein 5 gene and depressive symptoms in Mexican population: Results from MxGDAR/Encodat cohort. 甲基- cpg结合结构域蛋白5基因与墨西哥人群抑郁症状的关系：来自MxGDAR/Encodat队列的结果

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-09 DOI: 10.47626/1516-4446-2024-3859

Marco Antonio Sanabrais-Jiménez, Beatriz Camarena, Alejandro Aguilar-García, Alma Delia Genis-Mendoza, José Jaime Martínez-Magaña, Humberto Nicolini, Jorge Ameth Villatoro-Velá, Marycarmen Bustos-Gamiño, María de Lourdes Gutiérrez-López, María Elena Medina-Mora

{"title":"Association between methyl-CpG-binding domain protein 5 gene and depressive symptoms in Mexican population: Results from MxGDAR/Encodat cohort.","authors":"Marco Antonio Sanabrais-Jiménez, Beatriz Camarena, Alejandro Aguilar-García, Alma Delia Genis-Mendoza, José Jaime Martínez-Magaña, Humberto Nicolini, Jorge Ameth Villatoro-Velá, Marycarmen Bustos-Gamiño, María de Lourdes Gutiérrez-López, María Elena Medina-Mora","doi":"10.47626/1516-4446-2024-3859","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3859","url":null,"abstract":"Objective: To explore the association between 75 candidate genes previously reported in subjects with anxiety symptoms (AS) and depressive symptoms (DS) in a Mexican cohort.Methods: The sample included 2012 individuals from the Mexican Genomic Database for Addiction Research (MxGDAR/Encodat) cohort, 198 showed AS, 266 DS, 66 anxiety and depressive symptoms (ADS), and 1482 healthy controls. The DI-PAD screening questionnaire was used to evaluate lifetime AS and DS. The sample was genotyped with the commercial microarray PsychArray BeadChip. We identified 707 SNPs of 75 genes previously associated with AS and DS. PLINK's logistic regression approach was performed.Results: The analysis showed association between the rs2437092 (p=3.89x10-5) of LAMA and rs11066591 (p=4.06x10-5) of MYO1H with anxiety and depressive symptomatology. Additionally, rs7578002 (p=7.9x10-6) and rs1234428 (p=1.94x10-5) of MBD5 found association with DS. However, after adjustment for age, sex, and the three genetic principal components, only the association of rs7578002 (p=5.85x10-5) and rs1234428 (p=8.15x10-5) of MBD5 with DS remained.Conclusions: Our study replicated the association between MBD5 and DS. The MBD5 protein is involved in gene silencing, suggesting its potential implication in the development of DS in the Mexican population.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142954113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Childhood family adversities and recurrence of depression in adulthood: finds of three ELSA-Brasil visits. 童年时期的家庭逆境和成年期抑郁症的复发：三次elsa巴西访问的发现。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-04 DOI: 10.47626/1516-4446-2024-3914

Maíra Barroso Léo, Sandhi Maria Barreto, Rosane Harter Griep, Ana Luísa Patrão, Lidyane do Valle Camelo, Maria Carmen Viana, Luana Giatti

{"title":"Childhood family adversities and recurrence of depression in adulthood: finds of three ELSA-Brasil visits.","authors":"Maíra Barroso Léo, Sandhi Maria Barreto, Rosane Harter Griep, Ana Luísa Patrão, Lidyane do Valle Camelo, Maria Carmen Viana, Luana Giatti","doi":"10.47626/1516-4446-2024-3914","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3914","url":null,"abstract":"Objective: To investigate the association between family adversities in childhood and depression in three follow-up visits of a cohort of Brazilian adults.Methods: A total of 12,636 participants from the Longitudinal Study of Adult Health (ELSA-Brasil), who attended three interview/examination visits (2008-2010, 2012-2014, and 2017-2019), were included. Five family dysfunctions and the childhood family dysfunction score (0, 1, and 2+ dysfunctions) were used. The Clinical Interview Schedule-Revised-CIS-R assessed depression in 3 visits (no, 1, and 2 or 3) Multinomial logistic regression models estimated crude and adjusted Odds Ratios (OR) and 95% confidence intervals (95%CI).Results: Mean age was 59.6 years (SD=8.8), 7.4% presented depression in 1 visit and 2.2% in 2 or 3 visits. After adjustments, compared to the absence of family dysfunction the presence of mental disorder (OR: 3.91; 95%CI: 2.94-5.21), substance abuse (OR: 2.14; 95%CI: 1.65-2.77) and parental separation (OR: 1.55; 95%CI: 1.12-2.15) increased the odds of depression in 2 or 3 visits. Exposure to 2+ family dysfunctions increased the odds of depression in 1 and in 2 or 3 visits, with a dose-response gradient.Conclusion: Exposure to family dysfunction in childhood contributes to the occurrence and recurrence of depression in adults. Interventions to prevent dysfunctional family environments and their repercussions on children can reduce the burden of depression.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142954114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Higher risks of hyperopia, myopia, astigmatism, and strabismus in children with autism spectrum disorder: a nationwide, population-based cohort study. 自闭症谱系障碍儿童患远视、近视、散光和斜视的风险：一项基于全国人口的队列研究。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-01 Epub Date: 2024-09-22 DOI: 10.47626/1516-4446-2023-3515

Yi-Lung Chen, Cheng-Fang Yen, Yu-Hung Lai, Ray C Hsiao, Wei-Po Chou

{"title":"Higher risks of hyperopia, myopia, astigmatism, and strabismus in children with autism spectrum disorder: a nationwide, population-based cohort study.","authors":"Yi-Lung Chen, Cheng-Fang Yen, Yu-Hung Lai, Ray C Hsiao, Wei-Po Chou","doi":"10.47626/1516-4446-2023-3515","DOIUrl":"10.47626/1516-4446-2023-3515","url":null,"abstract":"Objective: In this population-based cohort study, we compared the risks of incident hyperopia, myopia, astigmatism, and strabismus between children with autism spectrum disorder (ASD) and those without ASD.Methods: This study included children who were born in Taiwan at any time between 2004 and 2017, using data from the Taiwan Maternal and Child Health Database (TMCHD). We included 20,688 children with ASD and 2,062,120 matched controls to estimate the risks of incident hyperopia, myopia, astigmatism, and strabismus. Cox proportional hazards regression models were conducted for risk assessment. Models were adjusted for sex, calendar year of birth, and gestational age at birth. Statistical significance was determined through adjusted hazard ratios (aHRs) and 95%CIs.Results: Children with ASD had higher risks of incident hyperopia (aHR: 1.78; 95%CI 1.70-1.86), myopia (aHR: 1.27; 95%CI 1.24-1.30), astigmatism (aHR: 1.51; 95%CI 1.46-1.56), and strabismus (aHR: 2.18; 95%CI 2.05-2.32) compared to children without ASD.Conclusion: Clinicians should screen children with ASD for potential eye conditions. Further studies are required to elucidate the mechanisms linking ASD with eye diseases. In addition, studies should explore how the type and severity of ASD symptoms influence the detection of these eye conditions.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20233515"},"PeriodicalIF":3.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A hybrid model for predicting response to risperidone after first-episode psychosis. 预测首次精神病发作后对利培酮反应的混合模型。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-01 Epub Date: 2024-07-29 DOI: 10.47626/1516-4446-2024-3608

Giovany Oliveira Costa, Vanessa K Ota, Matheus Rodrigues Luiz, Joice Santos Rosa, Gabriela Xavier, Jessica Honorato-Mauer, Marcos L Santoro, Carolina Muniz Carvalho, Daniel A Cavalcante, Amanda V G Bugiga, Rodrigo A Bressan, Gerome Breen, Ary Gadelha, Cristiano Noto, Diego R Mazzotti, Sintia I Belangero

{"title":"A hybrid model for predicting response to risperidone after first-episode psychosis.","authors":"Giovany Oliveira Costa, Vanessa K Ota, Matheus Rodrigues Luiz, Joice Santos Rosa, Gabriela Xavier, Jessica Honorato-Mauer, Marcos L Santoro, Carolina Muniz Carvalho, Daniel A Cavalcante, Amanda V G Bugiga, Rodrigo A Bressan, Gerome Breen, Ary Gadelha, Cristiano Noto, Diego R Mazzotti, Sintia I Belangero","doi":"10.47626/1516-4446-2024-3608","DOIUrl":"10.47626/1516-4446-2024-3608","url":null,"abstract":"Objective: Patient response to antipsychotic drugs varies and may be related to clinical and genetic heterogeneity. This study aimed to determine the performance of clinical, genetic, and hybrid models to predict the response of patients in first-episode psychosis (FEP) to the antipsychotic risperidone.Methods: We evaluated 141 antipsychotic-naive FEP patients before and after 10 weeks of risperidone treatment. Patients who had a response rate equal to or higher than 50% on the Positive and Negative Syndrome Scale (PANSS) were considered responders (n=72; 51%). Analyses were performed using a support vector machine (SVM), k-nearest neighbors (kNN), and random forests (RF). Clinical and genetic (with single-nucleotide variants [SNVs]) models were created separately. Hybrid models (clinical + genetic factors) with and without feature selection were created.Results: Clinical models presented greater balanced accuracy (63.3%; CI 0.46-0.69) with the SVM algorithm than the genetic models (balanced accuracy: 58.5% [CI 0.41-0.76], kNN algorithm). The hybrid model, which included duration of untreated psychosis, Clinical Global Impression-Severity (CGI-S) scale scores, age, cannabis use, and 406 SNVs, showed the best performance (balanced accuracy: 72.9% [CI 0.62-0.84], RF algorithm).Conclusion: A hybrid model including clinical and genetic predictors can enhance prediction of response to antipsychotic treatment.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20243608"},"PeriodicalIF":3.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Moral harassment and mental health in medical residents: a longitudinal study. 医学住院医生的道德骚扰与心理健康：纵向研究。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-01 Epub Date: 2024-09-22 DOI: 10.47626/1516-4446-2024-3579

Ana Bresser Tokeshi, Renato Antunes Dos Santos, Luiz Antonio Nogueira-Martins, Maria do Patrocinio Tenório Nunes, Thiago Marques Fidalgo

{"title":"Moral harassment and mental health in medical residents: a longitudinal study.","authors":"Ana Bresser Tokeshi, Renato Antunes Dos Santos, Luiz Antonio Nogueira-Martins, Maria do Patrocinio Tenório Nunes, Thiago Marques Fidalgo","doi":"10.47626/1516-4446-2024-3579","DOIUrl":"10.47626/1516-4446-2024-3579","url":null,"abstract":"Objective: This study investigated whether moral harassment contributes to anxiety, depression, and burnout among medical residents.Methods: This three-stage longitudinal study involved 218 1st-year residents, of whom 76 (34.9%) participated in all stages. The questionnaire covered demographics, mental health (using the Patient Health Questionnaire-4), burnout (using the Maslach Burnout Inventory Human Services Survey), and harassment experiences. Mental health outcomes and harassment were analyzed using logistic regression.Results: Anxiety and depression scores varied significantly, including a notable decrease in the personal accomplishment dimension of burnout. The prevalence of harassment was above 90%, and most victims were disturbed by the harassment they suffered. While a direct correlation between harassment victimization and reduced mental health was not found, seeking help exacerbated suffering, and depression and emotional exhaustion increased less among surgical residents.Conclusion: To the extent of our knowledge, this is the first longitudinal study on mental health and harassment among medical residents. The mental suffering experienced after taking action against harassment suggests that safe environments for addressing these issues are lacking in medical residencies. Further studies concerning surgical residents could shed light on their lower levels of suffering. Institutional changes are needed to support victims and create a healthy environment.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20243579"},"PeriodicalIF":3.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mental health predictors of Internet Gaming Disorder: a longitudinal study. 网络游戏障碍的心理健康预测因素：一项纵向研究。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-01 Epub Date: 2024-09-27 DOI: 10.47626/1516-4446-2024-3816

Guilherme Borges, Ricardo Orozco, Raúl Gutierrez-Garcia, Yesica Albor, Ana Lucía Jiménez Pérez, Karla Patrica Valdés-García, Patricia M Baez Mansur, María Anabell Covarrubias Dýaz-Couder, Corina Benjet

{"title":"Mental health predictors of Internet Gaming Disorder: a longitudinal study.","authors":"Guilherme Borges, Ricardo Orozco, Raúl Gutierrez-Garcia, Yesica Albor, Ana Lucía Jiménez Pérez, Karla Patrica Valdés-García, Patricia M Baez Mansur, María Anabell Covarrubias Dýaz-Couder, Corina Benjet","doi":"10.47626/1516-4446-2024-3816","DOIUrl":"10.47626/1516-4446-2024-3816","url":null,"abstract":"Objective: We investigated whether a wide range of baseline mental disorders among university students predict Internet gaming disorder (IGD) 1 to 3 years later.Methods: This prospective cohort study was conducted in six Mexican universities and had a 1- to 3-year follow-up period (September 2018 to June 2022). Participants were 1st-year university students (n=2,144) free of symptoms indicative of IGD at entry (baseline). Ten mental disorders (bipolar, major depressive disorder, generalized anxiety disorder, panic disorder, alcohol use disorder, drug use disorder, binging and/or purging, intermittent explosive disorder, psychotic experiences, and attention deficit hyperactivity disorder) at baseline were investigated as risk factors for IGD at the end of the follow-up. We used Cox regression to model the IGD incidence rate.Results: Any baseline mental disorder was associated with a 2.33 times (1.26-4.31) higher rate of IGD 1 to 3 years later. Several individual disorders were associated with rates of IGD in multiple models, with comorbid conditions diminishing most of these associations.Conclusion: Only major depressive disorder and bipolar disorder remained associated with new cases of IGD. The discrepant results of longitudinal studies on the role of specific mental disorders in the development of IGD should be further investigated.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20243816"},"PeriodicalIF":3.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142352903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trajectories of anxiety, depression, and posttraumatic stress among healthcare workers during the COVID-19 pandemic: one-year monthly follow-up. COVID-19 大流行期间医护人员的焦虑、抑郁和创伤后应激反应轨迹：为期一年的每月随访。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-01 Epub Date: 2024-09-22 DOI: 10.47626/1516-4446-2024-3720

Marcos O Carvalho-Alves, Vitor A Petrilli-Mazon, Pedro Fonseca Zuccolo, Daniel Fatori, Francisco Marcelo Monteiro Rocha, Andre R Brunoni, Guilherme V Polanczyk, Eurípedes C Miguel, Yuan-Pang Wang, Felipe Corchs

{"title":"Trajectories of anxiety, depression, and posttraumatic stress among healthcare workers during the COVID-19 pandemic: one-year monthly follow-up.","authors":"Marcos O Carvalho-Alves, Vitor A Petrilli-Mazon, Pedro Fonseca Zuccolo, Daniel Fatori, Francisco Marcelo Monteiro Rocha, Andre R Brunoni, Guilherme V Polanczyk, Eurípedes C Miguel, Yuan-Pang Wang, Felipe Corchs","doi":"10.47626/1516-4446-2024-3720","DOIUrl":"10.47626/1516-4446-2024-3720","url":null,"abstract":"Objective: To assess longitudinal patterns of anxiety, depression, and posttraumatic stress symptoms, as well as their predictors, among workers at a referral hospital during the first two waves of the coronavirus disease 2019 (COVID-19) pandemic in Brazil.Methods: Data were collected between July 2020 and June 2021 (n=1,078). Anxiety, depression, and posttraumatic stress symptoms were assessed using three self-report scales: the Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-9 (PHQ-9), and Impact of Event Scale-Revised (IES-R). Predictor analysis included COVID-19-related events, fear of COVID-19, and institutional support. Statistical analysis involved linear mixed models (LMM) and local polynomial regressions.Results: Anxiety and depression trended towards increased reactivity, while posttraumatic stress presented a downward trend over follow-up, with less fluctuation. Predictor analysis showed that higher levels of institutional support were associated with a reduced risk of all adverse mental health outcomes; conversely, greater fear of COVID-19 was positively associated with all such outcomes.Conclusion: Our findings underscore the importance of allocating enhanced attention and resources to effectively addressing personal health challenges among the health workforce, emphasizing the significance of organizational support and continuous monitoring of emotional distress.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20243720"},"PeriodicalIF":3.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The cost of dementia in Brazil. 巴西老年痴呆症的成本。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-01 Epub Date: 2024-11-17 DOI: 10.47626/1516-4446-2024-3611

Fabiana Araújo Figueiredo da Mata, Ari Alex Ramos, Laiss Bertola, Thais Suarez, Cleusa Pinheiro Ferri, Haliton Alves de Oliveira Júnior

{"title":"The cost of dementia in Brazil.","authors":"Fabiana Araújo Figueiredo da Mata, Ari Alex Ramos, Laiss Bertola, Thais Suarez, Cleusa Pinheiro Ferri, Haliton Alves de Oliveira Júnior","doi":"10.47626/1516-4446-2024-3611","DOIUrl":"10.47626/1516-4446-2024-3611","url":null,"abstract":"Objective: Given the increasing number of people with dementia in Brazil, health and social systems must urgently plan strategies to meet the needs of this population and their families. Therefore, research on dementia costs is essential. This study estimated direct and indirect dementia-related costs in Brazil.Methods: We used a cost-of-illness methodology to estimate dementia-related costs, in addition to household interview data from the National Report on Dementia in Brazil (ReNaDe) and public national databases to collect data on health service use and costs. Both a social and a health system perspective were used.Results: The monthly cost of dementia per patient increases with advancing stages of the syndrome: USD 843.04 in the initial stage, USD 1,317.81 in the intermediate stage, and USD 1,576.15 in the advanced stage. Indirect costs represent = 73% of total expenses. The country's total expenses are the highest during the intermediate stage of dementia.Conclusion: Family caregivers shoulder at least 73% of the health-related costs of dementia in Brazil, highlighting the need for better support strategies for people with dementia and their families.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20243611"},"PeriodicalIF":3.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142648416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addressing the elephant in the screening room: an item response theory analysis of the Prodromal Questionnaire for at-risk symptoms of psychosis. 解决筛查室中的大象问题：针对精神病高危症状的前驱症状问卷（PQ-16）的项目反应理论分析。

IF 3.6 3区医学

Revista Brasileira de Psiquiatria Pub Date : 2025-01-01 Epub Date: 2024-08-19 DOI: 10.47626/1516-4446-2024-3614

Christophe Gauld, Pierre Fourneret, Ben Alderson-Day, Emma Palmer-Cooper, Clément Dondé

{"title":"Addressing the elephant in the screening room: an item response theory analysis of the Prodromal Questionnaire for at-risk symptoms of psychosis.","authors":"Christophe Gauld, Pierre Fourneret, Ben Alderson-Day, Emma Palmer-Cooper, Clément Dondé","doi":"10.47626/1516-4446-2024-3614","DOIUrl":"10.47626/1516-4446-2024-3614","url":null,"abstract":"Objective: Patients at risk of psychosis present a variety of symptoms, and identifying the most discriminative symptoms is essential for efficient detection and treatment.Methods: This cross-sectional online study analyzed individuals from the general population to better assess their risk of symptoms classified as clinical high risk (CHR) for psychosis. The 16-item Prodromal Questionnaire was applied as a self-report screening tool. Item response theory with a graded response model was used to assess the discrimination and difficulty of the questionnaire's criteria.Results: The analysis included 936 participants (mean age: 21.5 years; 71.9% women). \"Déjà vu\" stood out for its high discriminative power, while the \"voices or whispers\" and \"seeing things\" items had greater precision than the other CHR-related symptoms. Conversely, the \"smell or taste\" and \"changing faces\" items were associated with the most severe cases.Conclusion: This study identified the most indicative CHR-related symptoms for accurate assessment of psychosis severity, which can be used to guide targeted preventative interventions.","PeriodicalId":21244,"journal":{"name":"Revista Brasileira de Psiquiatria","volume":" ","pages":"e20243614"},"PeriodicalIF":3.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0