Psychiatry Investigation最新文献

{"title":"Comparison of Neurophysiological Characteristics Using Heart Rate Variability Between Patients With Korean Hwa-byung and Healthy Individuals.","authors":"Sun-Woo Chung, Ki-Hwan Yook, Chun Il Park, Ji Eun Kim, Sang-Hyuk Lee, Hyun-Ju Kim","doi":"10.30773/pi.2026.0187","DOIUrl":"10.30773/pi.2026.0187","url":null,"abstract":"<p><strong>Objective: </strong>Hwa-byung (HB) is a syndrome associated with stressful events within Korea's social and cultural contexts. The clinical symptoms of HB may be associated with autonomic imbalance. This study investigated the neurophysiological characteristics of HB by comparing heart rate variability (HRV) between patients with HB and healthy controls (HCs).</p><p><strong>Methods: </strong>This study included 67 patients with HB and 72 HCs. We used psychological assessments, including trauma, life events, anger, and affective symptoms, along with the Hwa-Byung Scale (HBS). Neurophysiological data were evaluated by measuring HRV parameters. Statistical analyses included independent t-tests, chi-square tests, and Pearson correlation analyses.</p><p><strong>Results: </strong>Patients with HB showed significantly higher early trauma, and total HBS, Aggression Questionnaire-hostility, and State-Trait Anger Expression Inventory-2 (STAXI-2) state anger and anger suppression subscale scores. The HB group exhibited a higher low-frequency (LF)/ high-frequency (HF) ratio, higher LF, lower HF, lower total power, and lower very low frequency values. Within the HB group, Pearson's correlation analyses revealed positive significant correlations of the LF/HF ratio with HBS total score, HBS symptom subscale score, and STAXI-2 anger control-in scores.</p><p><strong>Conclusion: </strong>The study findings provide new insights into the neurophysiological characteristics of patients with HB compared with those of HCs, as measured by HRV. The HB group exhibited an imbalance in the autonomic nervous system. Moreover, the significant correlations between HB symptoms and the LF/HF ratio suggest that the LF/HF ratio may serve as a physiological marker of the severity of the clinical symptoms of HB.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"23 10","pages":"1298-1306"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Gene Signatures and Molecular Mechanisms Underlying the Comorbidity of Alzheimer's Disease and Crohn's Disease Using Machine Learning.","authors":"Hongwei Liu, Zhaoxu Yin, Zhinan Ye, Hao Xu","doi":"10.30773/pi.2026.0214","DOIUrl":"10.30773/pi.2026.0214","url":null,"abstract":"<p><strong>Objective: </strong>Alzheimer's disease (AD) and Crohn's disease (CD) both involve inflammation and immune dysregulation, yet the potential molecular mechanisms underlying their comorbidity remain unclear.</p><p><strong>Methods: </strong>We integrated transcriptomic data from AD and CD patients and applied differential expression analysis, weighted gene coexpression network analysis, protein-protein interaction networks, and multiple machine learning approaches to identify key comorbidity genes. Functional enrichment, single-cell sequencing validation, and virtual knockout analyses were used to explore their biological roles. Molecular docking was performed to evaluate the binding affinity of candidate small-molecule drugs to the identified core genes.</p><p><strong>Results: </strong>CXCL1 and IGFBP5 were identified as core comorbidity genes. CXCL1 was associated with inflammatory signaling, including cytokine receptor binding, neutrophil migration, and NOD-like receptor signaling. IGFBP5 was linked to growth factor binding, smooth muscle cell proliferation, and extracellular matrix-receptor interactions. Single-cell and virtual knockout analyses indicated that these genes play pivotal roles in inflammation, immune regulation, cell migration, and tissue remodeling, potentially bridging central and peripheral inflammation via the gut-brain axis and IgSF CAM signaling. Candidate drug prediction and molecular docking suggested that small molecules such as Dasatinib, Mifepristone, and Retinoic acid may modulate these pathways.</p><p><strong>Conclusion: </strong>This study reveals the critical roles of CXCL1 and IGFBP5 in AD-CD comorbidity, providing a theoretical basis for exploring gut-brain axis mechanisms and potential targeted interventions.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":" ","pages":"1278-1297"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Network Structure and Central Symptoms of Depression in Older Korean Adults: A Community-Based Analysis.","authors":"Jimin Lee, Byung-Soo Kim, Jee Eun Park, Sung Man Chang","doi":"10.30773/pi.2026.0063","DOIUrl":"10.30773/pi.2026.0063","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the network structure of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV)-defined depressive symptoms in a large, community-dwelling sample of older Korean adults, to better understand symptom interrelationships and their potential clinical implications in late-life depression.</p><p><strong>Methods: </strong>Depressive symptoms were assessed using the Korean version of the Composite International Diagnostic Interview 2.1, which includes both DSM-IV and 10th revision of the International Classification of Diseases symptom assessments. A total of 16 DSM-IV-defined symptom variables were derived based on diagnostic criteria and included in the network analysis (n=2,007). Network analysis was conducted using phi coefficients, community detection, and centrality and predictability. Sex-specific network structures were also compared.</p><p><strong>Results: </strong>Two distinct symptom clusters were identified. Suicide attempt emerged as one of the symptoms with relatively high betweenness centrality and predictability, suggesting a potentially distinctive position within the network, despite its relatively peripheral placement in the network visualization. Low energy, reduced self-confidence, and concentration difficulties also showed high degree and closeness centrality. The network among female participants was denser, particularly around suicide-related symptoms, and older female participants showed higher symptom prevalence and a slightly higher mean age.</p><p><strong>Conclusion: </strong>These findings suggest that suicide-related symptoms may play a distinctive and potentially bridging role within the depressive symptom network of older Korean adults, rather than being uniformly central across all metrics. These results highlight the importance of considering symptom heterogeneity, sex differences, and cultural context when developing targeted prevention and intervention strategies in geriatric mental health.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"23 10","pages":"1317-1323"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of Metacognition, Mental Toughness, and Self-Efficacy With Eco-Anxiety in Adolescents: A Structural Equation Modeling.","authors":"Esra Sizer, Yeliz Balca Kaya, Gülnur Baş, Remzi Oğulcan Çıray, Serhat Nasıroğlu","doi":"10.30773/pi.2026.0154","DOIUrl":"10.30773/pi.2026.0154","url":null,"abstract":"<p><strong>Objective: </strong>Global warming is increasingly recognized as a significant current issue, and its consequences are becoming more serious over time. However, the environmental effects of global warming on children and adolescents have not yet been sufficiently understood. Our study examined metacognition, mental toughness, and self-efficacy as psychological predictors of eco-anxiety in adolescents using a structural equation modeling framework.</p><p><strong>Methods: </strong>A total of 334 adolescents aged 15-17 years completed standardized self-report measures assessing eco-anxiety, metacognition, mental toughness, and self-efficacy.</p><p><strong>Results: </strong>Eco-anxiety was analyzed within its four-factor structure to identify cognitive vulnerability and resilience-related mechanisms. Mental toughness was negatively associated with emotional symptoms (β=-0.288, p<0.001) and personal impact concerns (β=-0.259, p< 0.001). In contrast, metacognitive processes were positively associated with rumination (β=0.532, p<0.001) and emotional symptoms (β=0.307, p<0.001). Self-efficacy showed a differential pattern, being positively related to behavioral symptoms (β=0.194, p=0.003) while negatively associated with personal impact concerns (β=-0.156, p=0.007). Girl gender was associated with higher rumination (β=0.164, p=0.004).</p><p><strong>Conclusion: </strong>These findings indicate that eco-anxiety in adolescents represents a multidimensional construct shaped by distinct cognitive vulnerability and resilience-related mechanisms. Metacognitive processes, mental toughness, self-efficacy, and sociodemographic characteristics may be important relevant variables in understanding individual differences in eco-anxiety among adolescents. In our world where the challenges of climate change persist, it is recommended that future studies further investigate the potential benefits, for adolescents, of preventive mental health interventions targeting metacognitive processes, mental resilience, and self-efficacy related to eco-anxiety.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":" ","pages":"1256-1266"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interactive Media Engagement Predicts Posttraumatic Distress After Community Trauma: A National Repeated Cross-Sectional Study.","authors":"Sun Wook Jung, Mi Yeon Lee, Kang-Seob Oh, Young-Chul Shin, Dong-Won Shin, Sang-Won Jeon, Junhyung Kim, Eun Soo Kim, Se Youl Kim, Kwang-Yeol Lee, Nahyun Oh, Sra Jung, Sung Joon Cho","doi":"10.30773/pi.2026.0172","DOIUrl":"10.30773/pi.2026.0172","url":null,"abstract":"<p><strong>Objective: </strong>Media engagement is an important pathway for indirect exposure to community trauma, but little is known about how interactive platforms and meaning-making relate to posttraumatic psychological outcomes. This study examined whether different types of media usage, particularly interactive online engagement, predict acute and subacute posttraumatic distress following a communitylevel traumatic event.</p><p><strong>Methods: </strong>A two-wave nationwide repeated cross-sectional survey was conducted 2 weeks (n=1,703) and 2 months (n=2,220) post-incident, using stratified quota sampling. Depressive, anxiety, and posttraumatic stress (PTS) symptoms were assessed using the Patient Health Questionnaire-9, Generalized Anxiety Disorder 7-item scale, and the Posttraumatic Stress Disorder Checklist for the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Analyses included chi-square tests, analysis of covariance with Bonferroni correction, and multivariable regression models.</p><p><strong>Results: </strong>Interactive engagement correlated with elevated psychological distress at both time points. At 2 months, receiving information through online communities and sharing graphic content predicted greater symptom severity and higher odds of clinically significant depressive, anxiety, and PTS symptoms. Passive exposure to graphics was not associated with elevated distress and was linked to lower symptom prevalence. Personal relevance to victims and systemic attribution were also significant predictors, with media types showing clearer differences at 2 months.</p><p><strong>Conclusion: </strong>Posttraumatic distress following community trauma appears to be shaped more by patterns of interaction with trauma-related information than by visual exposure. Interactive online engagement may amplify psychological symptoms over time, highlighting the need for public health strategies that address interactive media environments.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"23 10","pages":"1307-1316"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive Flexibility as a Mediator Between Mentalization and Symptom Severity in Generalized Anxiety Disorder.","authors":"Cansu Ünsal Mavi, Esma Çörekli Kaymakçı, Zeliha Büşra Durgungöz, Hatice Kübra Çiçek Hekimsoy","doi":"10.30773/pi.2026.0160","DOIUrl":"10.30773/pi.2026.0160","url":null,"abstract":"<p><strong>Objective: </strong>Mentalization and cognitive flexibility are key constructs in contemporary models of anxiety psychopathology; however, their interrelationship in clinically diagnosed generalized anxiety disorder (GAD) remains insufficiently delineated. This study aimed to examine whether cognitive flexibility mediates the association between mentalization and anxiety severity.</p><p><strong>Methods: </strong>In this cross-sectional study, 110 patients with GAD, diagnosed according to DSM-5 criteria, completed the Mentalization Scale, Cognitive Flexibility Inventory, and Generalized Anxiety Disorder-7. Associations were assessed using Pearson correlation analyses, and mediation was examined using bias-corrected bootstrapping (5,000 resamples).</p><p><strong>Results: </strong>Cognitive flexibility was moderately negatively associated with GAD severity (r=-0.421, p<0.001), whereas mentalization showed a weaker but significant negative association (r=-0.293, p=0.002). In addition, mentalization and cognitive flexibility were strongly positively correlated (r=0.636, p<0.001). Mediation analysis revealed a significant indirect effect of mentalization on anxiety severity through cognitive flexibility (B=-0.083, 95% confidence interval [-0.132, -0.042], p=0.001), while the direct effect was not statistically significant.</p><p><strong>Conclusion: </strong>Cognitive flexibility significantly mediated the association between mentalization and anxiety severity; however, given the cross-sectional design, this finding should be interpreted as statistical mediation rather than evidence of a causal mechanism. Although causal inferences cannot be established due to the cross-sectional design, cognitive flexibility may represent a clinically relevant target for reducing anxiety symptoms. Future longitudinal and interventional studies are warranted to clarify the directionality and clinical implications of these findings.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"23 10","pages":"1232-1239"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationships Between Loneliness, Common Mental Disorders, and Lifetime Suicidality in a Korean Adult Population.","authors":"Minjeong Kim, Wonseok Lee, Moon-Doo Kim, Young-Eun Jung","doi":"10.30773/pi.2026.0036","DOIUrl":"10.30773/pi.2026.0036","url":null,"abstract":"<p><strong>Objective: </strong>Loneliness has emerged as a significant public health concern in Korea. Recent studies suggest that loneliness may be closely associated with common mental disorders (CMDs) and suicidal thoughts and behaviors. This study evaluated associations between loneliness, CMDs, and suicidality among Korean adults.</p><p><strong>Methods: </strong>Data were obtained from 704 individuals aged 18-79 years who participated in the Jeju Special Self-Governing Province Mental Health Survey 2023. Loneliness, CMDs, and lifetime suicidality were assessed using a structured interview (the Korean Composite International Diagnostic Interview) and standardized scales (Loneliness and Social Isolation Scale).</p><p><strong>Results: </strong>High levels of loneliness were associated with CMDs and lifetime suicidality. After adjustment, demographic factors were not independently associated with suicidality, whereas CMDs remained a significant predictor. Loneliness demonstrated an independent association with suicidality and was associated with higher suicidality risk, particularly among individuals with CMDs.</p><p><strong>Conclusion: </strong>Loneliness independently contributes to suicide risk beyond the effects of CMDs, emphasizing the importance of public health interventions that address social engagement to prevent suicidal behaviors.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"23 10","pages":"1324-1329"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Preliminary Validation of the Korean Version of the Mental Illness: Clinicians' Attitudes Scale (MICA-4): Psychometric Properties and Healthcare Provider Stigma.","authors":"Ki Doh Kim, Hye Young Park, Haeji Shin, Hong Jin Jeon","doi":"10.30773/pi.2026.0149","DOIUrl":"10.30773/pi.2026.0149","url":null,"abstract":"<p><strong>Objective: </strong>Mental illness-related stigma among healthcare providers constitutes a critical barrier to care. The Mental Illness: Clinicians' Attitudes Scale (MICA-4) is a validated measure of healthcare provider stigma, but no Korean-language version exists. Our objective was to develop and validate a Korean version of the MICA-4, examining psychometric properties and associations with healthcare provider characteristics.</p><p><strong>Methods: </strong>Ninety-two healthcare workers completed the Korean MICA-4. Following rigorous forward and back translation, exploratory factor analysis examined the instrument's structure. Group comparisons tested associations between MICA-4 scores and provider characteristics (specialty, experience, education).</p><p><strong>Results: </strong>Internal consistency was acceptable (α=0.673). An exploratory five-factor structure, broadly consistent with the original instrument, was identified and provisionally retained for interpretation, given the modest sample size and preliminary nature of the study. Psychiatry specialists demonstrated significantly less stigmatizing attitudes than non-psychiatry professionals (M=42.90 vs. 50.08, p<0.001). Mental health education completion within the past 12 months showed the strongest association with reduced stigma (p<0.001). Longer clinical experience was associated with higher stigma. Age, gender, and contact frequency were not significantly associated with stigma scores.</p><p><strong>Conclusion: </strong>The Korean MICA-4 shows preliminary evidence of reliability and validity for assessing healthcare provider stigma in Korea, although further validation with larger and more diverse samples is needed before firm conclusions can be drawn. The substantial association between recent mental health education and lower stigma suggests that targeted training programs could be a promising strategy to reduce stigma among healthcare professionals.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":" ","pages":"1343-1351"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain-Related Dysfunctional Beliefs About Sleep and Depression Mediate the Influence of Pain Severity on Fear of Progression Among Individuals With Cancer.","authors":"Soobeen Lee, Mohd Ashik Shahrier, Sumin Hong, Seockhoon Chung","doi":"10.30773/pi.2026.0111","DOIUrl":"10.30773/pi.2026.0111","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated whether pain severity contributes meaningfully to fear of progression (FoP) among individuals with cancer and assessed the mediating roles of psychological symptoms, specifically pain-related dysfunctional beliefs about sleep and depressive symptoms, in this association.</p><p><strong>Methods: </strong>We retrospectively reviewed medical records of 252 individuals with cancer who attended the Sleep Clinic for cancer patients at Asan Medical Center. Demographic and clinical data were extracted alongside responses to self-report questionnaires, including the Fear of Progression Questionnaire-Short Form (FoP-Q-SF), Pain-Related Beliefs and Attitudes about Sleep (PBAS), Patient Health Questionnaire-9 (PHQ-9), State subscale of the State-Trait Anxiety Inventory (STAI-S), Insomnia Severity Index (ISI), and numeric pain rating scales. Pearson correlation and linear regression analyses were conducted to examine associations among variables, particularly the contribution of pain and psychological symptoms to FoP. Mediation analysis was performed using maximum likelihood regression.</p><p><strong>Results: </strong>FoP-Q-SF scores were significantly positively correlated with pain (r=0.36, p<0.001), PBAS (r=0.43, p<0.001), ISI (r=0.25, p<0.001), PHQ-9 (r=0.66, p<0.001), and STAI-S (r=0.22, p<0.001). Linear regression analysis indicated that FoP-Q-SF scores were predicted by age (β=-0.28, p<0.001), pain (β=0.13, p=0.013), PBAS (β=0.15, p=0.007), and PHQ-9 (β=0.55, p<0.001). Mediation analysis demonstrated that pain exerted a direct effect on FoP-Q-SF scores, with both PBAS and PHQ-9 partially mediating this relationship.</p><p><strong>Conclusion: </strong>These findings suggest that pain-related dysfunctional beliefs about sleep and depressive symptoms mediate the influence of pain severity on fear of progression among individuals with cancer.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"23 10","pages":"1240-1247"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attitudes Toward Suicide Are Associated With Lifetime History of Depressive Symptoms and Suicide Attempts Among Entertainment Industry Workers in South Korea.","authors":"Chaeyoon Kang, Jihoon Jang, Woojae Myung, Kiwon Kim, Meerae Lim, Jihyun Baek, Jihyun Ahn, Hong Jin Jeon","doi":"10.30773/pi.2025.0451","DOIUrl":"10.30773/pi.2025.0451","url":null,"abstract":"<p><strong>Objective: </strong>Entertainment industry workers (EIWs) face unique psychosocial stressors, yet systematic research on the psychological contributors to their suicide risk is scarce.</p><p><strong>Methods: </strong>A cross-sectional online survey of 491 adult EIWs in South Korea (55.0% male; 75.2% aged 20-49 years) assessed lifetime history of depressive symptoms, suicidal ideation, suicide attempts, and attitudes toward suicide using the 20-item Attitudes Toward Suicide Scale (ATTS-20). Associations between ATTS-20 subfactors and mental health outcomes were analyzed using exploratory factor analysis and multivariable logistic regression adjusted for key covariates.</p><p><strong>Results: </strong>Lifetime prevalence of depressive symptoms, suicidal ideation, and suicide attempts was 72.5%, 53.8%, and 13.4%, respectively. In adjusted models, lifetime history of depressive symptoms and lack of social support were significantly associated with both lifetime suicidal ideation (adjusted odds ratio [aOR]=3.57, 95% confidence interval [CI]: 2.20-5.89; aOR=2.57, 95% CI: 1.52-4.43, respectively) and suicide attempts (aOR=4.95, 95% CI: 1.88-17.10; aOR=2.67, 95% CI: 1.44-4.96, respectively). Regarding ATTS-20 factors, \"permissiveness\" and \"unpredictability\" were significantly associated with lifetime history of depressive symptoms (aOR=1.67, 95% CI: 1.22-2.30; aOR=1.48, 95% CI: 1.12-1.97, respectively) in multivariable analysis. Notably, the \"relation-caused\" factor (believing suicide is triggered by external relational problems) was significantly associated with suicide attempts (aOR=1.41, 95% CI: 1.01-2.00).</p><p><strong>Conclusion: </strong>This study found high prevalence of lifetime depressive symptoms, suicidal ideation, and suicide attempts among South Korean adult EIWs. In multivariable adjusted models, attitudes toward suicide of EIWs were associated with their lifetime depressive symptoms and suicide attempts.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":" ","pages":"1330-1342"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}