Functioning Level as a Buffer: Longitudinal Associations Between Heart Rate Variability and Post-Traumatic Stress Disorder Risk Over 2 Years.

IF 1.8 4区医学 Q3 PSYCHIATRY

Psychiatry Investigation Pub Date : 2025-09-16 DOI:10.30773/pi.2025.0084

Jae-Min Kim, Hee-Ju Kang, Ju-Wan Kim, Hyunseok Jang, Jung-Chul Kim, Ju-Yeon Lee, Sung-Wan Kim, Il-Seon Shin

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引用次数: 0

Abstract

Objective: This study examined the modifying effects of functional levels on the associations of the low frequency (LF) and high frequency (HF) components of heart rate variability (HRV) with post-traumatic stress disorder (PTSD) development.

Methods: Participants with physical injuries were recruited from a trauma center and followed for 2 years. Baseline assessments included LF, HF, and functional levels measured by the Social and Occupational Functioning Scale. Socio-demographic and clinical covariates were collected. PTSD diagnoses were made at 3, 6, 12, and 24 months post-injury using the Clinician-Administered PTSD Scale for DSM-5. Logistic regression analyses were performed to assess associations. Among 538 participants, 58 (10.8%) developed PTSD during the study period.

Results: A significant modifying effect was found: lower LF/HF were significantly associated with PTSD in patients with lower functioning levels, but not in those with higher functioning levels, with significant interaction terms.

Conclusion: The study observed functioning level-dependent associations between LF/HF and PTSD development, highlighting the buffering effects of higher functioning levels. These findings underscore the importance of considering functional status in PTSD risk assessments and the potential benefits of interventions aimed at enhancing social and occupational functioning to mitigate PTSD risk.

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功能水平作为缓冲：2年内心率变异性与创伤后应激障碍风险之间的纵向关联。

目的：探讨功能水平对心率变异性（HRV）低频（LF）和高频（HF）成分与创伤后应激障碍（PTSD）发展的相关性的调节作用。方法：从创伤中心招募有身体损伤的参与者，随访2年。基线评估包括LF、HF和社会与职业功能量表测量的功能水平。收集社会人口统计学和临床协变量。创伤后应激障碍的诊断分别在损伤后3、6、12和24个月使用DSM-5的临床应用PTSD量表。进行逻辑回归分析以评估相关性。在538名参与者中，58名（10.8%）在研究期间患上了PTSD。结果：在功能水平较低的患者中，低LF/HF与PTSD显著相关，而在功能水平较高的患者中，低LF/HF与PTSD显著相关，且存在显著的相互作用项。结论：本研究观察到LF/HF与PTSD发展之间的功能水平依赖关系，强调了高功能水平的缓冲作用。这些发现强调了在PTSD风险评估中考虑功能状态的重要性，以及旨在增强社会和职业功能以减轻PTSD风险的干预措施的潜在益处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Psychiatry Investigation PSYCHIATRY-

CiteScore

4.10

自引率

3.70%

发文量

105

审稿时长

6-12 weeks

期刊介绍： The Psychiatry Investigation is published on the 25th day of every month in English by the Korean Neuropsychiatric Association (KNPA). The Journal covers the whole range of psychiatry and neuroscience. Both basic and clinical contributions are encouraged from all disciplines and research areas relevant to the pathophysiology and management of neuropsychiatric disorders and symptoms, as well as researches related to cross cultural psychiatry and ethnic issues in psychiatry. The Journal publishes editorials, review articles, original articles, brief reports, viewpoints and correspondences. All research articles are peer reviewed. Contributions are accepted for publication on the condition that their substance has not been published or submitted for publication elsewhere. Authors submitting papers to the Journal (serially or otherwise) with a common theme or using data derived from the same sample (or a subset thereof) must send details of all relevant previous publications and simultaneous submissions. The Journal is not responsible for statements made by contributors. Material in the Journal does not necessarily reflect the views of the Editor or of the KNPA. Manuscripts accepted for publication are copy-edited to improve readability and to ensure conformity with house style.