{"title":"Child’s dignity in suffering and death.","authors":"Grażyna Cepuch, Agnieszka Kruszecka-Krówka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The magnitude of unfair, absurd,\u0000pointless suffering we cannot accept\u0000or understand makes it a phenomenon\u0000which defies human logic - especially\u0000when it concerns children. The source\u0000of suffering of a dying child is pain,\u0000fear, failure to satisfy the basic human\u0000needs and concern about the parents.\u0000It is also heightened by medical procedures,\u0000including treatments aimed\u0000at preventing the unavoidable death.\u0000Such actions, resulting from the fear\u0000of death and a lack of acceptance of\u0000death as the end of life burdened with\u0000suffering, pose a risk to the child’s fundamental\u0000rights and violate the source\u0000of human freedom - one’s inalienable\u0000dignity.\u0000Our priority should be to unconditionally\u0000respect the children’s rights\u0000postulated by Korczak, to ensure\u0000that while providing holistic care for\u0000a dying child, their dignity is always\u0000considered the greatest good.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36042809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Robert Krysiak, Karolina Kowalcze, Agnieszka Kędzia, Bogusław Okopień
{"title":"[Thyroid and aging: the present state of art].","authors":"Robert Krysiak, Karolina Kowalcze, Agnieszka Kędzia, Bogusław Okopień","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Aging is associated with important\u0000changes in thyroid hormone secretion,\u0000metabolism, and action. It\u0000remains unclear, however, whether\u0000altered activity of the hypothamic-pituitary-\u0000thyroid axis represents physiologic\u0000changes in thyroid function or\u0000whether they are secondary to thyroid\u0000dysfunction. The prevalence of\u0000thyroid disorders increases with age,\u0000but because some thyroid-associated\u0000symptoms are similar to symptoms\u0000of the aging process, these disorders\u0000are relatively rarely diagnosed. On the\u0000other hand, because of the possible\u0000presence of chronic, non-thyroidal\u0000illnesses or pharmacotherapy, diagnosis\u0000of thyroid disorders in older\u0000populations is often much more challenging\u0000than in young people. Progress\u0000made in better understanding\u0000of thyroid disorders in older people\u0000has thrown a new light on the management\u0000of patients with these disorders,\u0000the clinical picture of which is\u0000often atypical. Therefore, physicians\u0000need a high index of suspicion to detect\u0000thyroid dysfunction in an older\u0000person with multiple comorbidities\u0000and chronic polypharmacy. The purpose\u0000of this article is to review the\u0000present state of knowledge on the\u0000age-related changes in hypothalamicpituitary-\u0000thyroid axis activity and to\u0000discuss the clinical course, diagnosis\u0000and treatment of thyroid disorders in\u0000the elderly.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36044189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Protein-bound uremic toxins - biological effects and impact on morbidity in patients with chronic kidney disease.","authors":"Małgorzata Gomółka, Stanisław Niemczyk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cardiovascular complications\u0000are the main cause of increased\u0000mortality in patients with chronic kidney\u0000disease. Besides traditional risk\u0000factors, accumulated uremic toxins\u0000contribute to the accelerated atherosclerosis,\u0000which is accompanied by\u0000the progression of chronic kidney\u0000disease. Increased clearance of toxins\u0000with low molecular weight does\u0000not significantly improve survival of\u0000hemodialysis patients, and therefore\u0000the role and influence of other toxins,\u0000including protein-bound solutes\u0000(PBS) is intensively investigated. In\u0000our work, PBS is discussed on the\u0000example of indoxyl sulphate and pcresol\u0000sulphate. These substances\u0000are highly bound to proteins and\u0000removed from the circulation during\u0000dialysis to a small extent only.\u0000In our article, pathophysiological effects,\u0000the impact on the progression\u0000of chronic kidney disease and the\u0000survival of patients were discussed.\u0000We also assessed available methods\u0000of removing toxins from the system.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36044188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jerzy Wiliński, Anna Skwarek, Agnieszka Kasprzyk, Bogdan Wiliński, Tomasz Kameczura, Mikołaj Drzysztof Głowacki
{"title":"Right-sided aortic arch with aberrant left subclavian artery and hearing loss in patient with abnormal cardiomediastinal contours in routine chest X-ray.","authors":"Jerzy Wiliński, Anna Skwarek, Agnieszka Kasprzyk, Bogdan Wiliński, Tomasz Kameczura, Mikołaj Drzysztof Głowacki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Although the development of\u0000technologically advanced imaging\u0000techniques has progressively reduced\u0000the use of chest X-ray in clinical\u0000practice, it is still an invaluable\u0000tool to evaluate different diseases of\u0000the respiratory and cardiovascular\u0000systems. We are presenting a case\u0000of a 55-year-old male with arterial\u0000hypertension, severe mixed hearing\u0000loss who was referred to an internal\u0000medicine ward due to abnormal mediastinal\u0000and cardiac contours observed\u0000in a routine chest X-ray. The\u0000finding was linked to an anomalous\u0000aortic course what was confirmed\u0000within transthoracic echocardiography.\u0000The computed tomography angiography\u0000of the whole aorta revealed\u0000the right sided aortic arch (RSAA)\u0000with four large arteries arising from\u0000the aortic arch, including the aberrant\u0000left subclavian artery compressing\u0000the esophagus causing though\u0000no symptoms. Since RSAA might be\u0000associated with other cardiovascular\u0000diseases and genetic disorders including\u000022q11.2 deletion syndrome,\u0000we have conducted a complex diagnostics\u0000which showed additionally\u0000a decreased level of lymphocytes.\u0000The patient did not consent to genetic\u0000diagnostics and was qualified\u0000for conservative treatment of his disorders.\u0000In conclusion, a plain chest\u0000radiograph with the assessment\u0000of heart silhouette must not be neglected\u0000in cardiologic diagnostics.\u0000The identification of even asymptomatic\u0000aortic anatomic variant should\u0000be followed by the whole aorta angiography\u0000and a detailed assessment\u0000of the patient. RSAA bears potential\u0000risk of tracheostomy bleeding, unforeseen\u0000problems in transradial\u0000coronary procedures and potential\u0000problems during thyroid surgery,\u0000also because of abnormal recurrent\u0000laryngeal nerves’ course.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36044190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Damian Ucieklak, Joanna Zięba-Parkitny, Elżbieta Kozek, Jan Skupień, Krystyna Sztefko, Maciej T Małecki
{"title":"[Hypoglycemia due to antibodies to exogenous insulin in a patient with type 2 diabetes – a case report of treatment with new generation oral hypoglycemic agents].","authors":"Damian Ucieklak, Joanna Zięba-Parkitny, Elżbieta Kozek, Jan Skupień, Krystyna Sztefko, Maciej T Małecki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hypoglycemic syndromes associated\u0000with immune reactions against\u0000insulin are rare phenomena described\u0000predominantly in Asians. Steroid\u0000therapy, immunosuppression or plasmapheresis\u0000is often required.</p><p><strong>Case report: </strong>A 73-year-old White\u0000woman with a 20-year history of type\u00002 diabetes was admitted to hospital\u0000due to recurrent incidents of hypoglycemia\u0000that started several months\u0000after insulin initiation (lispro 75/25)\u0000and increased in severity over the\u0000next 5 years. They were accompanied\u0000by postprandial hyperglycemia up\u0000to 25 mmol/l. The patient’s glycated\u0000hemoglobin (HbA1c) was 70 mmol/\u0000mol (8.6%). During hypoglycemic\u0000episodes recorded serum C-peptide\u0000was 0.57-0.73 nmol/l (1.7-2.2 ng/ml),\u0000while insulin concentration exceeded\u00007000 pmol/l (1000 mIU/l). Surreptitious\u0000insulin administration was ruled out as\u0000was, based on diagnostic imaging, the\u0000presence of an insulin secreting tumor.\u0000Anti-insulin antibody (AIA) level measured\u0000by 125I-insulin binding method was\u000092.5% (normal < 8.2%). Hypoglycemic\u0000episodes occurred for four days after\u0000discontinuation of insulin therapy\u0000and then resolved completely. Good\u0000glycemic control was maintained with\u0000metformin, acarbose and dapagliflozin.\u0000Three months later dapagliflozin was\u0000replaced with vildagliptine due to poor\u0000tolerance of a SGLT-2 inhibitor. Patient’s\u0000HbA1c was 54 mmol/mol (7.1%),\u0000total fasting insulin level 2577 pmol/l\u0000and AIA binding 85.9%. Over the next\u0000year the patient has not experienced\u0000hypoglycemia and maintained good\u0000glycemic control, as HbA1c level was 53\u0000mmol/l (7.0%) and AIA binding 39.5%.</p><p><strong>Conclusions: </strong>In this rare case of\u0000a patient with diabetes and hypoglycemic\u0000syndrome related to AIA, we\u0000achieved a rapid and stable remission\u0000of hypoglycemia without immunosuppression.\u0000Good glycemic control, despite 20-year history\u0000of diabetes was achieved with oral hypoglycemic agents.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36041723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacek Piątek, Janusz Konstanty-Kalandyk, Anna Kędziora, Bryan Hyochan Song, Karol Wierzbicki, Tomasz Darocha, Dorota Sobczyk, Bogusław Kapelak
{"title":"Minimally invasive direct coronary artery bypass (MIDCAB) – safety assessment in own material.","authors":"Jacek Piątek, Janusz Konstanty-Kalandyk, Anna Kędziora, Bryan Hyochan Song, Karol Wierzbicki, Tomasz Darocha, Dorota Sobczyk, Bogusław Kapelak","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Minimally invasive\u0000direct coronary artery bypass (MIDCAB)\u0000allows achieving similar safety\u0000and efficacy, with markedly reduced\u0000post-operative length of stay when\u0000compared to conventional surgical\u0000revascularization. Despite promising\u0000results, a small number of minimally\u0000invasive procedures are performed in\u0000Poland. The aim of the study is to assess\u0000short- and long-term outcome of\u0000MIDCAB revascularization in order to\u0000evaluate the safety of the procedure.</p><p><strong>Materials and methods: </strong>Retrospective\u0000observational study analyzing 38\u0000consecutive patients who underwent\u0000MIDCAB procedure between 2014 to\u00002016 in the Department of Cardiovascular\u0000Surgery and Transplantology\u0000at the John Paul II Hospital, Kraków.\u0000Perioperative data was obtained from\u0000patient medical records and the median\u0000follow-up period valued 17.3\u0000months.</p><p><strong>Results: </strong>No postoperative deaths\u0000and only 1 case of postoperative\u0000myocardial infarction were observed.\u0000Throughout the follow-up period, the\u0000survival rate and freedom from MACCE\u0000rate valued 100%, with only 1 case\u0000of repeated revascularization.</p><p><strong>Conclusions: </strong>Minimally invasive\u0000revascularization is a safe procedure\u0000which can be performed with excellent\u0000short- and long-term outcome in\u0000low-risk patients.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36041728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tomasz Basta, Iwona Gawron, Krzysztof Mirocki, Dorota Babczyk, Robert Jach
{"title":"[Analysis of histological type and staging of cervical cancer as prognostic factors among women treated in the Department of Gynecology and Oncology, Jagiellonian University in the years 2001-2014].","authors":"Tomasz Basta, Iwona Gawron, Krzysztof Mirocki, Dorota Babczyk, Robert Jach","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Cervical cancer (CC)\u0000is the fourth most common, in terms\u0000of incidence of new cases, cancer in\u0000women and the third leading cause of\u0000cancer deaths in women worldwide.\u0000Survival of patients with CC depends\u0000on many factors, including the type\u0000of cancer, grading, FIGO staging and\u0000treatment.</p><p><strong>Material and methods: </strong>Analysis of survival of 524 patients diagnosed\u0000with invasive and non-invasive CC depending\u0000on histopathologic diagnosis,\u0000clinical staging, tumor grading and\u0000combination of therapy.</p><p><strong>Results: </strong>The 2-fold increase in the\u0000risk of death at diagnosis in order of\u0000HSIL> ca planoepitheliale> adenocarcinoma>\u0000sarcoma was noted. Grading\u00002 and 3 significantly reduces the average\u0000survival in patients diagnosed with\u0000CC. The higher staging, the shorter the\u0000average survival. Each pass by one\u0000FIGO stage was shown to increase\u0000the risk of death by 46%. The risk of\u0000death increases by 4% with every year\u0000of woman’s life. The longest average\u0000survival, 72 months, characterized a\u0000group of women undergoing curettage,\u0000followed by radical hysterectomy/\u0000trachelectomy and lymphadenectomy\u0000without adiuvant radio-/ chemotherapy.\u0000The shortest survival, 26.9 months,\u0000was observed in the group treated with\u0000curettage followed by chemoradiation.</p><p><strong>Conclusions: </strong>Histopathology, clinical staging, grading, age and\u0000combination of treatment proved to be\u0000significant factors affecting survival in\u0000women with CC.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36042808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Agnieszka Zapora-Kurel, Marta Rydzewska, Maciej Edward Małyszko, Adrianna Zajkowska, Natalia Anna Drobek, Jolanta Małyszko
{"title":"Anemia in diabetic kidney disease - underappreciated but still clinically relevant problem.","authors":"Agnieszka Zapora-Kurel, Marta Rydzewska, Maciej Edward Małyszko, Adrianna Zajkowska, Natalia Anna Drobek, Jolanta Małyszko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Anemia is the most common disorder\u0000of the blood with iron deficiency\u0000being the predominant cause. On the\u0000other hand, diabetes prevalence is\u0000increasing rapidly. Over time, diabetes\u0000can damage the heart, blood\u0000vessels, eyes, kidneys, and nerves.\u0000Diabetic kidney disease (DKD) may\u0000be present in both types 1 and type\u00002 diabetes mellitus. Anemia is one of\u0000the common feature of chronic kidney\u0000disease. The epidemiological data on\u0000anemia prevalence are limited. In this\u0000review data on epidemiology, pathogenesis,\u0000complication and treatment\u0000of anemia in diabetic kidney disease\u0000are presented.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36044338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iwona Gawron, Magdalena Łoboda, Dorota Babczyk, Inga Ludwin, Paweł Basta, Kazimierz Pityński, Artur Ludwin
{"title":"Endometrial cancer and hyperplasia rate in women before menopause with abnormal uterine bleeding undergoing endometrial sampling.","authors":"Iwona Gawron, Magdalena Łoboda, Dorota Babczyk, Inga Ludwin, Paweł Basta, Kazimierz Pityński, Artur Ludwin","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Abnormal uterine\u0000bleeding (AUB) is the most common\u0000symptom of endometrial cancer (EC)\u0000and endometrial hyperplasia with\u0000(AH) or without (EH) atypia. Risk of\u0000malignancy and hyperplasia is significantly\u0000lower in premenopausal\u0000than in postmenopausal women. Only\u000010% of EC occurs before menopause.\u0000Obesity and age are well-recognized\u0000risk factors of endometrial cancer.\u0000Endometrial sampling is recommended\u0000in women at high risk of endometrial\u0000malignancy. The primary objective\u0000was to determine the incidence\u0000of EC, AH and EH in premenopausal\u0000women undergoing dilation and curettage\u0000(D&C) because of AUB. Additional\u0000objective of the study was\u0000to estimate the risk of EC and AH in\u0000overweight and obese women with\u0000two types of AUB: heavy menstrual\u0000bleeding (AUB-HMB) and intermenstrual\u0000bleeding (AUB-IMB), according\u0000to PALM-COEIN classification.</p><p><strong>Material and methods: </strong>Retrospective\u0000study in the population of women\u0000undergoing D&C in tertiary hospital\u0000because of AUB between Jan-2016\u0000and Dec-2016. The incidence of EC,\u0000AH, EH was established. The influence\u0000of the variables: age, BMI, AUBHMB/\u0000AUB-IMB on the occurrence of\u0000abnormal histology (EC, AH, EH) was\u0000evaluated. Finally, the model built by\u0000using backward stepwise regression\u0000and mechanism of v-fold cross-validation,\u0000showed no statistically significant\u0000relationship.</p><p><strong>Results: </strong>EC was detected in 2/213\u0000cases (0.9%; 95% CI 0.0003 to 0.036),\u0000AH in 3/213 cases (1.4%), giving a total\u0000of 5/213 (2.3%) women with AH or\u0000EC. EH was detected in 16/213 (7.5%)\u0000women. High BMI raises the chance of\u0000AH diagnosis: OR 1.16 (95% CI 1.05-\u00001.28). The presence of HMB compared\u0000to IMB reduces the chance of EH: OR\u00000.24 (95% CI 0.07-0.9). IMB increases\u0000the chance for the diagnosis of EH 4.11 times compared to\u0000HMB (OR 4.1, 95% CI 1.1-14.9; p = 0.016).</p><p><strong>Conclusions: </strong>EC in premenopausal women with AUB\u0000undergoing D&C is rare. There is a need to search for\u0000more effective methods of selection of patients than commonly\u0000used. Age and BMI do not seem to be factors that\u0000should be used to select patients.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36044568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aneta Kołodziej-Kłęk, Agnieszka Gala-Błądzińska, Krzysztof Okoń, Agnieszka Sadowska, Grzegorz Świder
{"title":"[Membranous nephropathy - the most commonly diagnosed glomerulopathy in patients who underwent renal biopsy in the Department of Internal Medicine, Nephrology and Endocrinology St. Queen Jadwiga Clinical District Hospital No. 2 in Rzeszow].","authors":"Aneta Kołodziej-Kłęk, Agnieszka Gala-Błądzińska, Krzysztof Okoń, Agnieszka Sadowska, Grzegorz Świder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We retrospectively analysed\u0000the results of 120 renal biopsy, performed\u0000in 52 women, 62 men and 6\u0000children hospitalized mainly in the\u0000Department of Internal Medicine,\u0000Nephrology and Endocrinology St.\u0000Queen Jadwiga Clinical District Hospital\u0000No. 2 in Rzeszów from 2013 to\u00002016. The average age of patients on\u0000whom renal biopsy was performed\u0000amounts to 44 (7-78) years. The most\u0000common indications for renal biopsy\u0000were nephrotic syndrome in 47 patients\u0000(37.3%), non-nephrotic proteinuria\u0000in 31 patients (24.6%), worsening\u0000renal function in 22 patients\u0000(17.5%), coexistence proteinuria with\u0000hematuria in 16 patients (12.7%), nephritic\u0000syndrome in 9 patients (7.1%)\u0000as well as an isolated hematuria in 1\u0000patient (0.8%). Membranous glomerulonephritis\u0000was the most common\u0000histological diagnosis observed in\u0000biopsies, and was diagnosed in 19\u0000patients (15.1%). In 14 patients we\u0000diagnosed lupus nephritis (11.1%).\u0000With the same frequency we diagnosed\u0000focal glomerulosclerosis, and\u0000mesangioproliferative glomerulonephritis\u0000(11 patients, 8,7%). Membraneproliferative\u0000glomerulonephritis was\u0000diagnosed in 10 patients (7.9%).\u0000Other nephropathy accounted for\u0000less than 8% of all diagnoses. Most\u0000patients with membranous nephropathy\u0000(8 patients, 61%) had antibodies\u0000against phospholipase A2 receptor.\u0000All patients with a diagnosis of membranous\u0000nephropathy received the renin-\u0000angiotensin-aldosterone system\u0000blockade, and 13 patients (68.4%) received\u0000immunosuppressive therapy.\u0000Complete remission was achieved in 11 patients (64.7%)\u0000with primary membranous nephropathy. In 35 patients\u0000(27.8%) of all patients who underwent renal biopsy they\u0000had complications after procedure in the form of small and\u0000clinically insignificant perirenal hematomas. Hematuria\u0000was observed in 7 cases (5.56%). In one case, due to retroperitoneal\u0000bleeding, the patient required a transfusion of\u0000blood products.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36045761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}