Przeglad lekarski最新文献

{"title":"[Vitamin D – from the past antirachitic factor to new pleiotropic substance].","authors":"Konrad Dobrzycki,&nbsp;Hanna Bachórzewska-Gajewska,&nbsp;Sławomir Dobrzycki,&nbsp;Jolanta Małyszko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Vitamin D is known for almost 100\u0000years. Since time of its discovery, numerous\u0000studies on vitamin D function\u0000in the human body were performed.\u0000Considered from the beginning as\u0000an important factor in rickets prevention,\u0000thanks to the continuous development\u0000of knowledge, vitamin D is\u0000regarded now as an important factor\u0000from the point of view of the whole\u0000body homeostasis. Newly-find features\u0000of vitamin D allow to use this\u0000substance concentration in serum\u0000as a biomarker of general health and\u0000create opportunities of vitamin D use\u0000in the prevention and treatment of\u0000many diseases. The aim of this article\u0000is to present basic function of\u0000vitamin D in human body, sources of\u0000this substance, its metabolism and\u0000molecular mechanism of action, taking\u0000into account the evolution of the\u0000state of knowledge about Vitamin D\u0000- from early researches leading to its\u0000discovery, through the finding of its\u0000basic functions to the present studies\u0000on vitamin D mechanisms of action at\u0000molecular and genomic level.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36044341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metformin and changes in serum lipid profile in lean patients with polycystic ovary syndrome.","authors":"Marta Kiałka,&nbsp;Anna Gałuszka-Bednarczyk,&nbsp;Anna Wajda,&nbsp;Patrycja Czekańska,&nbsp;Barbara Zdzierak,&nbsp;Sandra Mrozińska,&nbsp;Marek Janeczko,&nbsp;Tomasz Milewicz","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of our study\u0000was to assess the values of total cholesterol,\u0000high-density lipoprotein cholesterol\u0000(HDL-C), low-density lipoprotein\u0000cholesterol (LDL-C) and triglycerides\u0000before and after treatment with metformin\u0000in lean patients with polycystic\u0000ovary syndrome (PCOS).</p><p><strong>Material and methods: </strong>32 patients received metformin 1500 mg per day in\u0000three divided doses. Lipids measurements\u0000were performed twice: before\u0000and after 6 months of treatment with metformin.</p><p><strong>Results: </strong>In lean patients with\u0000PCOS after treatment with metformin\u0000we observed: statistically significant\u0000lower LDL-C levels (4.16±0.79 mmol/l\u0000vs 3.4±0.86 mmol/l, p<0.05) and triglycerides\u0000levels (1.8±0.53 mmol/l vs\u00001.12±0.64 mmol/l, p<0.05). We observed\u0000an increase in HDL values and a decrease\u0000in total cholesterol values, but\u0000these changes were not statistically significant\u0000(1.5±0.71 mmol/l vs 1.71±0.69\u0000mmol/l, p=0.09; 5.87±0.92 mmol/l vs\u00005.69±0.97 mmol/l, p=0.11).</p><p><strong>Conclusion: </strong>Our study showed that\u0000treatment of 1500 mg metformin for\u0000about six months among PCOS women\u0000results in an improvement in serum\u0000lipid profiles. We observed a significant\u0000decrease in LDL-C and triglycerides values\u0000after metformin therapy.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36044570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Cardiac complications in rheumatoid arthritis, systemic lupus erythematosus and systemic sclerosis].","authors":"Wojciech Gawrysiak,&nbsp;Katarzyna Skrypnik,&nbsp;Joanna Suliburska,&nbsp;Damian Skrypnik,&nbsp;Paweł Bogdański","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Connective tissue diseases are\u0000a group of more than 300 separate\u0000diseases. It can affect every system of\u0000organs, including the cardiovascular\u0000system. This process is particularly\u0000highly expressed in rheumatoid arthritis,\u0000systemic lupus erythematosus\u0000and scleroderma.\u0000Rheumatoid arthritis (RA) affects\u00000.5-1.0% of Europeans. The most\u0000common cardiac manifestation of RA\u0000is pericarditis. Its main risk factor is\u0000the occurrence of rheumatic nodules\u0000in people with the presence of\u0000serum rheumatoid factor. An important\u0000health problem in RA is also an\u0000increased risk of atherosclerosis and\u0000ischemic myocardial disease, the intensity\u0000of which grows independently\u0000of traditional risk factors and mainly\u0000depends on the severity of inflammation\u0000and duration of the disease. In\u0000rheumatoid arthritis also endocarditis,\u0000heart valves damage and ventricular\u0000arrhythmias can occure.\u0000Systemic lupus erythematosus\u0000(SLE) is most common in women\u0000between age 16 to 55. Cardiovascular\u0000complications of this disease are\u0000the third biggest cause of death of\u0000patients. The most common cardiac\u0000manifestation of SLE is pericarditis\u0000occurring in approximately 20 to 50%\u0000of the ill. Libman-Sacks non-infectious\u0000endocarditis characterized by\u0000thickening of the heart valves and the\u0000presence of non-bacterial vegetation\u0000is characteristic for SLE.\u0000Systemic sclerosis is characterized\u0000by progressive fibrosis of skin\u0000and internal organs and disorders of\u0000the morphology and function of blood\u0000vessels. Cardiac manifestations of\u0000systemic sclerosis are mainly heart\u0000failure and arrhythmias.\u0000The European League Against\u0000Rheumatism (EULAR) has developed\u0000a number of recommendations related\u0000to the prevention and therapy of\u0000cardiovascular events in RA. Since an\u0000increased risk of cardiovascular complications\u0000applies to many rheumatic\u0000diseases, there is a need to extend these recommendations\u0000to other connective tissue diseases.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36047834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Giant supernumerary parathyroid adenoma as a cause of persistent primary hyperparathyroidism in a patient with a multiglandular parathyroid disease].","authors":"Jaroslaw Szymon Świrta,&nbsp;Marcin Piejko,&nbsp;Marcin Barczyński,&nbsp;Piotr Wałęga","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Despite the significant progress\u0000that has been made in recent years in\u0000parathyroid imaging, improvements\u0000in surgical techniques and availability\u0000of surgical quality control based on\u0000intraoperative parathyroid hormone\u0000levels (PTH) assay, approximately\u00001-5% of patients undergoing surgery\u0000have state of persistent hyperparathyroidism.\u0000The most common causes of\u0000persistent hyperparathyroidism are:\u0000limited surgical experience, a failure to\u0000recognize multiglandular parathyroid\u0000disease, ectopic parathyroid adenoma\u0000location, insufficient range of resection\u0000of diseased parathyroid glands,\u0000parathyroid capsule tearing leading\u0000to parathyromathosis, as well as parathyroid\u0000cancer. In this clinical observation\u0000the case of a 52-years old man is\u0000described who underwent surgical\u0000removal of 2 parathyroid adenomas,\u0000and within few days he was found to\u0000have persistent hypercalcemia. After\u0000completing the diagnostic imaging and\u0000biochemical work-up that patient underwent\u0000bilateral neck re-exploration\u0000with removal of ectopic giant supernumerary\u0000parathyroid adenoma (60\u0000mm in diameter and 22.8 g in weight)\u0000which was localized in the upper part\u0000of the posterior mediastinum, resulting\u0000in stable normocalcemia afterwards.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36041724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients with diabetes mellitus have better lipid profile results compared to the controls - a retrospective study on a group of patients hospitalized due to pulmonary embolism.","authors":"Donat Domaradzki,&nbsp;Piotr J Stryjewski,&nbsp;Jacek Lelakowski,&nbsp;Agnieszka Kuczaj,&nbsp;Małgorzata Konieczyńska,&nbsp;Joanna Pudło,&nbsp;Katarzyna Cubera,&nbsp;Ewa Nowaqlany-Kozielska","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary embolism\u0000is a clinical manifestation of venous\u0000thromboembolism (VTE), also\u0000comprising deep vein thrombosis. It\u0000is considered to be a consequence\u0000of environmental and genetic factors.\u0000The number of predisposing risk factors\u0000is high. Some authors view VTE\u0000as a part of the cardiovascular disease\u0000continuum and suggest that cardiovascular\u0000disease risk factors such\u0000as the metabolic syndrome or diabetes\u0000mellitus may predispose to VTE.</p><p><strong>Aim: </strong>The analysis of patients hospitalized\u0000in the department of cardiology\u0000due to pulmonary embolism\u0000and a multifactorial comparison of 2\u0000groups of patients i.e. with and without\u0000diabetes mellitus.</p><p><strong>Patients and methods: </strong>A retrospective\u0000analysis of 11435 patient\u0000medical records from a 7-year period\u0000was performed. Patients with confirmed\u0000pulmonary embolism were\u0000enrolled for further evaluation. Sixty\u0000seven patients (36 women and 31\u0000men), aged 70.3±13.3 (age range: 30-\u000093) were divided into two groups i.e.\u0000patients with and without diabetes.\u0000The statistical analysis of the obtained\u0000results was performed using\u0000SPSS 21 Software.</p><p><strong>Results: </strong>Statistically significantly\u0000higher total, LDL, and HDL cholesterol\u0000concentrations were observed in\u0000patients without diagnosed diabetes.\u0000Similar significant differences were\u0000not observed for other cardiovascular\u0000risk factors except for hypertension\u0000and obesity which was more frequent\u0000in diabetic patients.</p><p><strong>Conclusions: </strong>In patients with pulmonary\u0000embolism the prevalence of diabetes\u0000was related to lower total, LDL\u0000and HDL cholesterol concentrations.\u0000The differences between the groups\u0000may be explained by more intensive\u0000medical surveillance in patients with\u0000previously diagnosed diabetes.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36041726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The most recent developments in diagnosis and treatment of multiple myeloma].","authors":"Artur Jurczyszyn,&nbsp;Magdalena Olszewska-Szopa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recently a great progress in the\u0000diagnosis and treatment of multiple\u0000myeloma has been made. Substantial\u0000revisions in diagnostic criteria were introduced.\u0000As a result a neoplasm called\u0000very high risk asymptomatic myeloma\u0000is currently regarded a disease that\u0000needs to be treated. The comprehension\u0000of progression mechanism and\u0000clonal evolution not only helped to\u0000understand the disease course but\u0000might contribute to expand treatment\u0000options and individualize the therapy.\u0000Modern triple therapy containing IMiDs\u0000and proteasome inhibitors resulted\u0000in the higher response rate than ever\u0000before which led to triple therapy incorporation\u0000as a frontline treatment.\u0000U.S. Food and Drug Administration\u0000(FDA) registered for new drugs in\u00002015 (two monoclonal antibodies and\u0000two oral drugs) in relapsed/refractory\u0000myeloma. Together with currently existing\u0000drugs it considerably expended\u0000the therapeutically spectrum. Even\u0000drugs that are not effective when used\u0000as a monotherapy like panobinostat\u0000and elotuzumab play important role\u0000in complex therapy, particularly in\u0000refractory patients. The most recent\u0000trials dedicated to the role of the novel\u0000drugs in the induction phase suggest\u0000that high–dose therapy followed by\u0000autologous stem cell transplantation\u0000improve progression free survival\u0000and quality of life. Myeloma treatment\u0000schedules incorporate more and more\u0000innovative immunotherapy methods:\u0000adoptive T-cell therapies, vaccines\u0000and monoclonal antibodies. Although\u0000multiple myeloma is still regarded\u0000incurable neoplasm, due to better\u0000disease understanding and access to\u0000novel drugs, we are getting closer than\u0000ever before to evolve therapy that will\u0000provide long-lasting effects or at least\u0000converting it into the chronic slowly\u0000developing disease.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36042811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The gastrointestinal tract microbiom in connective tissue diseases].","authors":"Magdalena Krajewska-Włodarczyk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Factors such as genetics, the environment,\u0000infections, and the human\u0000body microbiota, mainly gastrointestinal\u0000tract microbiota may play a role\u0000in the pathogenesis of autoimmune\u0000disorders. There is an increasing evidence\u0000that suggest an association between\u0000gastrointestinal tract dysbiosis,\u0000and in particular gut dysbiosis, and\u0000connective tissue diseases but it still\u0000remains unclear whether alterations\u0000in the microbiome are a pathogenic\u0000cause or an effect of autoimmune\u0000disease. Given the strong variability\u0000and abundance of microbes living in\u0000close relation with human host, it becomes\u0000a difficult task to define what\u0000should be considered the normal or\u0000the favorable microbiome. Further\u0000studies are needed to establish how\u0000the human microbiome contributes to\u0000disease susceptibility, and to characterize\u0000the role of microbial diversity in\u0000the pathogenesis of connective tissue\u0000diseases and their clinical manifestations.\u0000The identification of dysbiosis\u0000specific for certain connective tissue\u0000diseases may help in the development\u0000of an individualized management\u0000for each patient. This review aims to\u0000summarize current data on the role of\u0000the gastrointestinal tract microbiome\u0000in connective tissue diseases.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36045764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Percutaneous coronary intervention and minimally invasive aortic valve replacement for patients with aortic valve disease and coronary artery disease].","authors":"Jarosław Stoliński,&nbsp;Dariusz Plicner,&nbsp;Michal Mędrzyński,&nbsp;Bogusław Kapelak","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To report the results\u0000of hybrid approach combining percutaneous\u0000coronary intervention (PCI)\u0000and minimally invasive aortic valve\u0000replacement through right anterior\u0000minithoracotomy (RT-AVR) for patients\u0000with aortic valve disease and\u0000coronary artery disease.</p><p><strong>Materials and methods: </strong>Retrospective\u0000analysis of 53 hybrid RT-AVR/\u0000PCI procedures where RT-AVR was\u0000performed first in the operating room\u0000and followed immediately by PCI performed\u0000in the catheterization laboratory.</p><p><strong>Results: </strong>Predicted with Euro-\u0000SCORE II and observed hospital mortality\u0000was 8.7±2.9% and 1.9% respectively.\u0000Hospital and intensive care\u0000unit length of stay were 5.6±2.4 and\u00001.8±1.4 days respectively. Biological\u0000aortic valve prosthesis was implanted\u0000in 40 (75.5%) patients. PCI of LAD was\u0000performed in 5 patients (9.4%), of Dg\u0000in 10 (18.9%) patients, of Mg or Cx in\u000021 (39.6%) patients, of PDA or RCA in\u000025 (47.2%) patients. Two vessels and\u0000three vessels PCI were performed in\u00005 (9.4%) and 3 (5.7%) patients respectively.\u0000DES were used during PCI in\u000042 (79.2%) patients. Dual antiplatelet\u0000therapy with 75 mg of Aspirin and 75\u0000mg of Clopidogrel started after RTAVR/\u0000PCI. Complications occurred\u0000in 16 (30.2%) patients after hybrid\u0000RT-AVR/PCI procedure. Prolonged\u0000above 24 hours mechanical ventilation\u0000time was necessary in 3 patients\u0000(5.7%). Renal insufficiency occurred\u0000in 4 (7.5%), stroke in 1 (1.9%) patient.\u0000Pacemaker was implanted in 2 (3.8%)\u0000patients after surgery. Conversion to\u0000conventional surgery through median\u0000sternotomy was performed in 1 patient\u0000(1.9%), surgical revision due to\u0000postoperative bleeding in 2 patients\u0000(3.8%). No perioperative myocardial\u0000infarction and no mediastinitis was\u0000diagnosed after RT-AVR/PCI procedure.\u0000Postoperative chest blood\u0000drainage was 245.0±181.0 ml. Red blood cells transfusion\u0000was required in 10 (18.9%) patients.</p><p><strong>Conclusions: </strong>The hybrid RT-AVR/PCI procedure for\u0000these high risk patients with aortic valve disease and coronary\u0000artery disease presented in our series favourable\u0000mortality results compared to predicted with EuroSCORE\u0000II mortality for conventional cardiac surgery.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36045766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Outline of the history of caesarean section – from ancient times to the end of 17th Century].","authors":"Andrzej Torbé,&nbsp;Przemysław Ustianowski,&nbsp;Maria Ustianowska,&nbsp;Zbigniew Celewicz,&nbsp;Dorota Torbé","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Problems with the childbirth accompanied\u0000the human civilization\u0000since its beginning. From the ancient\u0000times, physicians and other people\u0000specializing in healing, tried to help\u0000women in this special moment of life.\u0000At the base of this exceptional meaning\u0000of childbirth for humans lies the\u0000fact, that if something is going wrong\u0000there are two victims - mother and the\u0000child.\u0000As a result, many times there had\u0000been very dramatic attempts of help\u0000in this the most difficult journey which\u0000in his life every man is undergoing. In\u0000this paper a comprehensive review of\u0000literature about the history of caesarean\u0000section from ancient times to the\u0000end of 17th century was done.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36041725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Health awareness and cooperation with the patient in the therapeutic process in a population of patients with chronic kidney disease in the center of Gdansk].","authors":"Zbigniew Heleniak,&nbsp;Magdalena Cieplińska,&nbsp;Tomasz Szychliński,&nbsp;Dymitr Rychter,&nbsp;Kalina Jagodzińska,&nbsp;Alicja Kłos,&nbsp;Izabella Kuźmiuk-Glembin,&nbsp;Leszek Tylicki,&nbsp;Bolesław Rutkowski,&nbsp;Alicja Dębska-Ślizień","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chronic kidney disease (CKD) is\u0000considered as a disease of civilization\u0000of the XXI century. The increase\u0000of patients with CKD is associated\u0000with a higher incidence of hypertension,\u0000diabetes and aging. Hypertension\u0000occurs in 60-90% of patients\u0000with CKD. It is worth to underline that\u0000the nephroprotective therapy can delay\u0000or even stop the progression of\u0000CKD to end-stage renal disease. The\u0000therapy nephroprotective should be\u0000understood as both pharmacological\u0000and nonpharmacological treatment.\u0000The aim of this study was to\u0000evaluate the health awareness of\u0000patients with CKD, as well as the\u0000degree of patient compliance especially\u0000in terms of pharmacological\u0000and non-pharmacological treatment.</p><p><strong>Material and methods: </strong>A crosssectional\u0000survey was offered for\u00001300 patients with CKD who are are\u0000under the care of the Department of\u0000Nephrology, Transplantology and Internal\u0000Medicine, University Hospital\u0000in Gdansk. 972 patients (M/F) (74.8%)\u0000responded positively to participate in\u0000the study</p><p><strong>Results: </strong>It was shown that 91.2%\u0000of the patients measured blood pressure\u0000at home. 41.2% measured blood\u0000pressure everyday and 54.2% of patients\u0000used at least one non-pharmacological\u0000treatment for hypertension.\u000071.7% of patients declared that buy\u0000all drugs prescribed by the doctor.\u000053.4% of patients used the possibility\u0000of substitution drugs prescribed\u0000by a doctor for cheaper preparations\u0000recommended by the pharmacist.\u000085.7% of patients taking medicines\u0000according to doctor’s advice (frequency,\u0000dose).</p><p><strong>Conclusions: </strong>The results of the\u0000study indicate that the education of\u0000patients, the therapeutic process and\u0000their health awareness are good, especially\u0000among patients treated with\u0000peritoneal dialysis. It should be continued\u0000as educational program because these activities\u0000may contribute to improving the prognosis and quality of\u0000life. A patients after kidney transplantation are particularly\u0000vulnerable to the effects of failure to comply with recommendations.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36042429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}