Radiation and Environmental Biophysics最新文献

{"title":"Application of the Avrami-Dobrzyński model for mammary tumorigenesis in irradiated rats indicates new candidates for parametric cancer risk assessment.","authors":"Julianna Krasowska, Tatsuhiko Imaoka, Krzysztof W Fornalski","doi":"10.1007/s00411-025-01125-3","DOIUrl":"10.1007/s00411-025-01125-3","url":null,"abstract":"<p><p>The two-parametric Avrami-Dobrzyński model, originally based on the condensed matter physics for phase transitions, was applied to the cumulative populational mammary cancer data of laboratory rats. The joint effect of parity, irradiation and BRCA1 mutation on breast cancer incidence was analysed. The study showed that the proposed model fits well with the data points, however, the values of parameters differ regarding the investigated group of animals. It was concluded that both model's parameters, which relate to the dimension of carcinogenesis dynamics and the age distribution, are good candidates for cancer risk assessment regarding different risk factors.</p>","PeriodicalId":21002,"journal":{"name":"Radiation and Environmental Biophysics","volume":" ","pages":"229-239"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative dosimetric assessment of combined treatment modalities in cervical cancer radiotherapy for optimal organ protection.","authors":"Iozsef Gazsi, Loredana G Marcu","doi":"10.1007/s00411-025-01113-7","DOIUrl":"10.1007/s00411-025-01113-7","url":null,"abstract":"<p><p>External radiotherapy combined with internal radiotherapy in cervical cancer can provide a boost to the target volume to increase tumour control. At the same time internal radiotherapy protects neighboring organs. The aim of the present study was to dosimetrically compare three external beam radiotherapy techniques each combined with internal radiotherapy to evaluate the combination that offers the best organ protection. Treatment plans of 20 cervical cancer patients were created for external (including three-dimensional conformal radiotherapy (3D-CRT), intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT)) as well as brachytherapy. The prescribed dose was 50 Gy in 25 fractions for external and 21 Gy in three fractions for internal radiotherapy. The following organs at risk (OARs) were evaluated: bladder, rectum, sigmoid and bowel bag. The study analyzed the results of different treatment combinations in terms of dosimetric values for various parameters. The D₉₀ for the clinical target volume was around 120 Gy, with the highest value seen in 3D-CRT + BT (brachytherapy) combination at 120.59 Gy. For the bladder, the D_2cc remained below the recommended threshold of 90 Gy, with the lowest value obtained for the BT + IMRT combination at 79.2 Gy. For the rectum, both D_2cc and D_1cc remained below the recommended threshold of 75 Gy for both parameters. All techniques fell below the recommended dose of 75 Gy for the sigmoid. For the intestine, there were statistically significant differences between BT + IMRT and BT + 3D-CRT. The VMAT technique showed superiority over IMRT in tumour volume coverage and several organ-at-risk parameters. Generally, intensity-modulated techniques showed dosimetric advantage over the traditional 3D technique in cervical cancer. In addition to providing better compliance and homogeneity, they provided superior protection for organs at risk, especially for bowel bag. It is concluded that the BT + IMRT technique provided the best protection for organs at risk based on the lowest OAR dosimetric values, especially for the intestine.</p>","PeriodicalId":21002,"journal":{"name":"Radiation and Environmental Biophysics","volume":" ","pages":"291-302"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049278/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-nanoparticle-based composite for diagnostic X-ray shielding in computed tomography applications: a Monte Carlo study.","authors":"Sofiene Mansouri","doi":"10.1007/s00411-025-01116-4","DOIUrl":"10.1007/s00411-025-01116-4","url":null,"abstract":"<p><p>While numerous studies have investigated the impact of various nanoparticles (NPs) in polymer matrices for radiation shielding, there is a notable gap in the literature regarding a comprehensive examination of both individual and combined selected NPs with functional polymers. This study aims to address this gap by systematically evaluating the synergistic potential of multiple high-Z NPs and specialized polymer matrices in radiation shielding design, particularly for computed tomography (CT) applications. A single and mixture range of NPs, including Gd₂O₃, Sm₂O₃, CeO₂, HfO₂, IrO₂, Bi₂O₃, and WO₃, were combined with polymers such as chlorinated polyvinyl chloride (CPVC), polychlorostyrene (PCS), polytrifluorochloroethylene (PTFCE), polytetrafluoroethylene (PTFE), polyvinyl chloride (PVC), and polyvinylidene chloride (PVDC) which served as matrices. By means of Geant4 Monte Carlo simulations, the study assessed the shielding effectiveness of these nanocomposites at various X-ray energies (80, 100, 120, and 140 kVp). The results revealed that nanocomposites containing Sm₂O₃ and Gd₂O₃ exhibited superior X-ray attenuation at 80 and 100 kVp, while the HfO₂ nanocomposite demonstrated enhanced shielding at 120 and 140 kVp. Additionally, multi-filler nanocomposites with 30 wt% of Sm₂O₃ + HfO₂ (SmHf) and Gd₂O₃ + Bi₂O₃ (GdBi) exhibited improved performance at 80 and 140 kVp, respectively. Notably, the 30 wt% Gd₂O₃ + IrO₂ (GdIr) multi-filler nanocomposite outperformed others at 100 and 120 kVp. It is concluded that a combination of NPs with K-edge values close to the mean energy of the investigated X-ray spectra provide better shielding capabilities than single NPs, highlighting their potential for applications in radiation protection.</p>","PeriodicalId":21002,"journal":{"name":"Radiation and Environmental Biophysics","volume":" ","pages":"263-274"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Assessing the correlation between Gamma passing rate and clinical dosimetric variations in breast cancer IMRT plans with multi-leaf collimator errors: perspectives from the ArcCHECK QA system.","authors":"Xiuquan Li, Jia Deng, Xiangyang Wu, Hang Yang, Dengdian Huang","doi":"10.1007/s00411-025-01107-5","DOIUrl":"10.1007/s00411-025-01107-5","url":null,"abstract":"","PeriodicalId":21002,"journal":{"name":"Radiation and Environmental Biophysics","volume":" ","pages":"337"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Relationships between protection and operational dosimetric quantities for external exposure to natural background radiation.","authors":"A Ulanowski, T Sato, N Petoussi-Henss, M Balonov","doi":"10.1007/s00411-025-01118-2","DOIUrl":"10.1007/s00411-025-01118-2","url":null,"abstract":"","PeriodicalId":21002,"journal":{"name":"Radiation and Environmental Biophysics","volume":" ","pages":"335"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Internal radiation dose to the herring gull embryo due to ⁹⁰Sr in the egg.","authors":"E A Shishkina, E Khramova, N Mogilnikova, G A Tryapitsina, E A Pryakhin","doi":"10.1007/s00411-025-01119-1","DOIUrl":"10.1007/s00411-025-01119-1","url":null,"abstract":"<p><p>Birds are bioindicators of anthropogenic environmental stress, including the changes caused by radioactive contamination of ecosystems. Any radiation-induced biological effects can be the consequence of exposure both after hatching and during the embryonic period. Therefore, it is necessary to quantify radiation doses to the embryo when interpreting observed radiobiological effects in birds. This is especially true for areas contaminated with Ca-like ⁹⁰Sr. The levels of radionuclide accumulation in the eggshell can be extremely high, which leads to chronic embryo exposure. Consequently, the objective of the present study was to develop a method to calculate the dose to a herring gull embryo exposed to ⁹⁰Sr distributed in egg compartments (shell, embryo body, albumen and yolk). To achieve this, the time-dependent Sr distribution in the egg compartments was modeled. Additionally, dosimetric modeling was carried out to obtain dose factors that convert the radionuclide activity in different compartments of an egg to embryo dose at various stages of embryogenesis. It has been shown that the accumulated dose to the herring gull embryo can be calculated based on ⁹⁰Sr total activity in the egg using a dose conversion factor of 0.44 μGy Bq^-1. Since the eggshell contains more than 90% of total ⁹⁰Sr activity, the conversion from eggshell activity to embryo dose would be practically the same as that from the total egg activity - 0.46 μGy Bq^-1. The main dose fraction (~ 99%) accumulates at the last stage of embryogenesis (from 13 to 26 days). The proposed method allows for an estimation of individual radiation doses to embryos based on eggshell radiometry. This creates a new opportunity to study how dangerous any radiation exposure of birds could be during the embryonic period.</p>","PeriodicalId":21002,"journal":{"name":"Radiation and Environmental Biophysics","volume":" ","pages":"311-319"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maintaining competence in radiation protection research: a position statement by the MELODI scientific advisory committee.","authors":"Sally A Amundson, Mauro Belli, Maria Blettner, Kerstin Borgmann, Eva Forssell-Aronsson, Mats Harms-Ringdahl, Penelope A Jeggo, Ohtsura Niwa, Peter O'Neill","doi":"10.1007/s00411-025-01122-6","DOIUrl":"10.1007/s00411-025-01122-6","url":null,"abstract":"<p><p>The aim of this position statement is to bring to the forefront the necessity for maintaining and enhancing high competence in assessing the impact of low dose and low dose rate exposure on human health and the urge for funding to achieve this within Europe. Exposure to low dose/dose rates of radiation can arise from multiple scenarios or events, including natural radiation exposure, the use of radiation in medicine, industry and energy production, terrorist actions and following a nuclear incident or war. Technological developments involving radiation are progressing rapidly and have the potential to benefit mankind and societal issues. The benefit of high dose exposure during radiotherapy is a well-funded area. However, the health consequences of exposure to low doses is not well understood and the area of radiation protection research (RPR) is poorly funded. High quality RPR is essential to allow updating of radiation safety regulations for optimal protection from natural, medical and occupational exposure and for assessment of radiation incidents. Continuous evaluation of risks is essential as technological developments result in new types of radiation exposure. We will overview the technologies and situations which can potentially lead to low dose exposure, evaluate what has been gained from RPR and the questions that still need addressing, discuss the current state of RPR in Europe and highlight the consequences of a failure to adequately fund this area. We conclude that increased funding for RPR is essential to maintain high competence and to allow adequate protection of the public to inevitable low dose radiation exposure.</p>","PeriodicalId":21002,"journal":{"name":"Radiation and Environmental Biophysics","volume":" ","pages":"201-209"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing texture analysis of pretreatment ¹⁸F-FDG PET and ⁶⁸Ga-PSMA PET in patients with prostate cancer: investigation of diagnostic efficacy and prognostic biomarker.","authors":"Mahmoud A Kenawy, Hussein M Abdelhafez, Murtadha Al-Fatlawi, Tariq Nadhim Jassim, Ahmed Salman Jasim, Elsayed M Alashkar","doi":"10.1007/s00411-025-01114-6","DOIUrl":"10.1007/s00411-025-01114-6","url":null,"abstract":"<p><p>This study aims to evaluate the predictive accuracy of textural parameters and current parameters of ¹⁸F-fluorodeoxyglucose and ⁶⁸Ga-labeled prostate-specific antigen positron emission tomography (FDG and PSMA PET) images in prostate cancer (PCa) and compare the features retrieved from both scans. Based on symptoms, digital rectal examination (DRE), prostate-specific antigen (PSA) level in the blood, or histopathology from transrectal ultrasound-guided biopsy and 4Kscore Test, 120 patients have confirmed PCa. Sixty of them were scanned on a PET/CT machine using ¹⁸F-FDG, and the other 60 patients were scanned using ⁶⁸Ga-PSMA of radiopharmacy. Each tumour was delineated using PET. Edge texture parameters were used to define each tumour, and 73 features in all were taken from eight distinct texture matrices and computed using the open-source program Chang-Gung Image Texture Analysis (CGITA). Using Spearman correlation, feature correlation with conventional quantitative metrics (Maximum Standardized Uptake Value (SUVmax), Total Lesion Glycolysis (TLG), Metabolic Tumor Volume (MTV)) was investigated, and it was found that the High-Intensity Low-Energy Radiation (HILRE) correlation was strong. PCa was best discriminated by HILRE (64-bin) in receiver operating characteristic curves. It is concluded that ⁶⁸Ga-PSMA-based PET imaging is better than ¹⁸F-FDG-based PET and is strongly associated with PCa tumour allocation. According to extracted features, HILRE is the most significant measure and it is, thus, considered here an independent predictor of PCa prognosis. Although the study's findings are helpful, confirmation by further prospective research is required.</p>","PeriodicalId":21002,"journal":{"name":"Radiation and Environmental Biophysics","volume":" ","pages":"253-261"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commissioning and performance assessment of diodes and MOSFETs in in-vivo dosimetry for external beam radiation therapy.","authors":"Omama Al Kharusi, Raya Al Mamari, Balaqis Al Hosni, Iqbal Al Amri, Mahmoud Al Fishawy, Mohamed-Rachid Boulassel, Yassine Bouchareb","doi":"10.1007/s00411-025-01117-3","DOIUrl":"10.1007/s00411-025-01117-3","url":null,"abstract":"<p><p>The precision of radiation therapy treatment depends on several calibration and quality assurance processes. In-vivo dosimetry (IVD) is used in external beam radiotherapy to evaluate the delivered versus planned dose as a patient-specific quality assurance verification procedure. This study aimed at assessing the performance of diodes (EDP-103G and EDP-203G) and metal oxide semiconductor field-effect transistors (MOSFETs) and corresponding correction factors followed by IVD evaluation in different treatment configurations. Linearity, stability, gantry angle, field size, and source-to-subject distance (SSD) were assessed across various photon energies, with correction factors determined. To minimize patient movement uncertainty, the study utilized the Alderson Rando phantom to replicate clinical setups, comparing diode and MOSFET dose readings to treatment planning system (TPS) doses. Diodes and MOSFETs were evaluated across different photon energy levels for brain, chest, and pelvis planning sites. Diodes and MOSFETs demonstrated good stability and linearity at the different utilized photon beams. Data analysis showed that MOSFETs had a slightly higher sensitivity compared to diodes in gantry angle, field size and SSD corrections. Regarding the validation process after applying the correction factors, dose variations between diode readings and TPS doses were found to be 1.89%, 1.58%, and 6.72% for brain, breast, and pelvis, respectively. In contrast, MOSFET readings were 2.40% for brain, 2.03% for chest, and 2.03% for pelvis. It is concluded that, while diode and MOSFET dosimeters both allowed for accurate patient dose measurements, for different anatomical sites, MOSFETs demonstrated better performance for the pelvis compared to diodes.</p>","PeriodicalId":21002,"journal":{"name":"Radiation and Environmental Biophysics","volume":" ","pages":"275-289"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of meteorological factors and atmospheric particulate matter on background radiation.","authors":"Mao-Chin Hung","doi":"10.1007/s00411-025-01121-7","DOIUrl":"10.1007/s00411-025-01121-7","url":null,"abstract":"<p><p>The interactions between meteorological factors, atmospheric particulate matter (PM), and background radiation were investigated in this study. Three databases that recorded these data in Taipei were used and multiple linear regression was applied to analyze the data. It turned out the distributions of meteorological factors, PM2.5 and PM10 concentrations, and background radiation differed significantly between periods of sunny and rainy hours. Background radiation was positively correlated with temperature and relative humidity, but negatively correlated with wind speed on sunny and rainy days. In particular, background radiation significantly increased with PM2.5 and PM10 concentrations on sunny days or nights. However, on rainy days or nights, the background radiation significantly increased with precipitation, regardless of the PM concentration. The effects of PM2.5, PM10 and precipitation on background radiation were found to last up to 1, 5 and 4 h, respectively. In conclusion, meteorological factors and PM have significantly different effects on background radiation on sunny and rainy hours.</p>","PeriodicalId":21002,"journal":{"name":"Radiation and Environmental Biophysics","volume":" ","pages":"321-328"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}