Reactive & Functional Polymers最新文献

{"title":"Sustained release polyurethane microcapsules by interfacial polycondensation using aromatic diols","authors":"Prashant Yadav ,&nbsp;Aniruddha Ravikumar ,&nbsp;Ashootosh V. Ambade ,&nbsp;Kadhiravan Shanmuganathan","doi":"10.1016/j.reactfunctpolym.2025.106460","DOIUrl":"10.1016/j.reactfunctpolym.2025.106460","url":null,"abstract":"<div><div>Polyurea-urethane (PUU) microcapsules prepared via interfacial polymerization have gained significant interest due to their tunable size and membrane thickness, high loading efficiency, and scalability. Although several aromatic and aliphatic diols and polyols have been used to produce PU foams and films, the use of aromatic diols to synthesize PUU MICs via interfacial polymerization is an unexplored domain due to the restricted solubility of aromatic diols in water. This report highlights the successful preparation of PUU microcapsules using an aromatic diol (benzene-1,4-dimethanol, BDM) to encapsulate dimethyl phthalate (DMP), a model insect repellent. The developed PUU microcapsules exhibited a high % encapsulation efficiency of 92 % and a size range of 1–20 μm. Differential scanning calorimetry (DSC) thermograms revealed a significantly high glass transition temperature (T_g) of 143 °C as compared to 108 °C in the case of PUU MICs with aliphatic diols. Release studies confirm enhanced barrier properties for aromatic diol-based MICs as compared to aliphatic ethylene glycol-based PUU MICs, and interpretation of the release profile using the Weibull Model reveals that Fickian diffusion is the dominant mechanism in the release of DMP. These microcapsules can be used in high-performance applications such as composites, coatings, electronics, and construction.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"216 ","pages":"Article 106460"},"PeriodicalIF":5.1,"publicationDate":"2025-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144912103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interfacial polymerization combined with etching: A novel surface modification method for ultrafiltration membranes","authors":"Shiwei Guo ,&nbsp;Xinlu Yan ,&nbsp;Junhou Zhang ,&nbsp;Liang Gou ,&nbsp;Yunjin Ma ,&nbsp;Hao Wang ,&nbsp;Chungang Yuan","doi":"10.1016/j.reactfunctpolym.2025.106459","DOIUrl":"10.1016/j.reactfunctpolym.2025.106459","url":null,"abstract":"<div><div>This study presents a novel surface modification method for ultrafiltration membranes via interface polymerization combined with etching, with the objective of enhancing their separation performance and antifouling properties. Polyethersulfone (PES) ultrafiltration membranes were modified via interfacial polymerization of polyethylene glycol (PG) with trimesoyl chloride (TMC) to form a polyester separation layer. This was followed by alkaline etching, which served to remove the majority of the polyester layer, leaving a residual portion that was then employed to modify the membrane surface. The modified membranes displayed enhanced hydrophilicity and a diminished surface charge, which resulted in an elevated level of antifouling performance. The successful modification of the membranes was confirmed by physicochemical characterizations, including scanning electron microscopy (SEM), atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), and contact angle measurements, which also demonstrated an enhanced hydrophilicity. The results of the separation performance tests demonstrated that the modified membranes retained their original separation properties while exhibiting enhanced flux recovery rates following the introduction of fouling cycles. The results of the long-term stability tests demonstrated that the modified membranes retained their performance over an extended period, indicating their potential for practical applications. The findings of this study offer a promising approach to enhancing the performance of ultrafiltration membranes in industrial separation processes.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"216 ","pages":"Article 106459"},"PeriodicalIF":5.1,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144895454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid polyurethane acrylate films via thiol–ene click and sol–gel reactions: Monomer-dependent structure–property relationships","authors":"Bilge Eren ,&nbsp;Sibel Taşpınar ,&nbsp;Rabia Balci ,&nbsp;Beyhan Erdoğan","doi":"10.1016/j.reactfunctpolym.2025.106452","DOIUrl":"10.1016/j.reactfunctpolym.2025.106452","url":null,"abstract":"<div><div>This study introduces a novel strategy for enhancing UV-curable polyurethane acrylate (PUA) coatings by integrating thiol–ene click chemistry with sol–gel processing. Hybrid polyurethane acrylate (HPUA) films were synthesized using biuret-type hexamethylene diisocyanate (HDI) and a pentaerythritol (PENTA) core, followed by end-capping with three structurally distinct acrylate monomers: 2-hydroxyethyl methacrylate (HEMA), 2-hydroxyethyl acrylate (HEA), and 2-hydroxypropyl methacrylate (HPMA). Subsequently, (3-mercaptopropyl)trimethoxysilane (MPTMS) was grafted onto the acrylate-terminated polymers via a thiol–ene click reaction under UV irradiation to introduce alkoxysilane groups for sol–gel hybridization. The objective was to investigate how monomer architecture influences the development of organic–inorganic networks and the resulting thermal, mechanical, and surface properties. FTIR spectral deconvolution confirmed enhanced hydrogen bonding and crosslinking, especially in HPMA-based systems. DSC and TGA results showed that HPMA–HPUA exhibited the highest glass transition temperature (<em>T</em>_g from −13.52 °C to 90.0 °C) and thermal stability (T₅₀ from 380 °C to 457 °C), attributed to improved interfacial compatibility with the silica network. Surface analyses revealed increased hardness and hydrophobicity after sol–gel modification, with contact angles rising up to 130°. This study establishes a clear structure–property relationship framework for monomer-dependent hybridization and presents a scalable approach for designing high-performance, UV-curable coatings with customizable thermal and mechanical properties.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"216 ","pages":"Article 106452"},"PeriodicalIF":5.1,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144912102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation and properties of highly electrically conductive and heat-resistant crosslinked polyimide-polypyrrole","authors":"Pan He ,&nbsp;Jinghua Tan ,&nbsp;Jie Huang ,&nbsp;Jieping Guo ,&nbsp;Penghao Yu ,&nbsp;Yue Chen ,&nbsp;Yiwu Liu","doi":"10.1016/j.reactfunctpolym.2025.106458","DOIUrl":"10.1016/j.reactfunctpolym.2025.106458","url":null,"abstract":"<div><div>With the growing interest in high-temperature conductive applications, the demand for electrical conductive polyimides (PIs) has surged. However, the existing conductive PIs still remain challenges in achieving a balance between high conductivity and good thermal performance. To obtain PI simultaneously exhibiting superior conductivity and thermal properties, in this study, a diamine (5-POPDA) bearing pyrrole moiety was prepared and subsequently polycondensed with 4,4′-(hexafluoroisopropylidene) diphthalic anhydride (6FDA) to yield poly(amic acid) (5-POPPAA). After being ionized, the 5-POPPAA was combined with dopants and pyrrole monomers to create a suspension, which was subsequently put through an electrophoretic deposition procedure. In the procedure, the 5-POPPAA film was deposited, and simultaneous electrochemical polymerization occurred between suspended pyrrole monomers and pendant pyrrole groups of 5-POPPAA to form polypyrrole (PPy). This resulted in the crosslinked 5-POPPAA-PPy, which was chemical imidized to yield crosslinked 5-POPPI-PPy. The creation of extended π-conjugated PPy structure resulted in a large conductivity of 10.53 S/cm for 5-POPPI-PPy. Additionally, 5-POPPI-PPy demonstrated excellent thermal stability with 5 % and 10 % weight-loss temperatures (<em>T</em>_<em>d5%</em> and <em>T</em>_{<em>d10%</em>}) of 453 °C and 479 °C, respectively, benefiting from the covalent crosslinking between the 5-POPPI and PPy molecular chains. Moreover, the crosslinked 5-POPPI-PPy film exhibited good mechanical characteristics and remarkable high-temperature conductivity retention. While pure PPy lost its conductivity by being annealed at 250 °C, 5-POPPI-PPy retained a conductivity of 6.23 S/cm. This study offers insightful theoretical information for the development of conductive PIs tailored for conductive applications in high temperature.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"216 ","pages":"Article 106458"},"PeriodicalIF":5.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144895455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polyurethane elastomer-based composites containing innovative hybrid fillers with tailored mechanical properties and enhanced bioactivity","authors":"Przemysław Bartczak ,&nbsp;Agata Domańska ,&nbsp;Filip Ciesielczyk ,&nbsp;Łukasz Ławniczak ,&nbsp;Monika Basiura-Cembala ,&nbsp;Weronika Badzińska ,&nbsp;Sławomir Borysiak","doi":"10.1016/j.reactfunctpolym.2025.106453","DOIUrl":"10.1016/j.reactfunctpolym.2025.106453","url":null,"abstract":"<div><div>The study presents previously unreported line of the research concerning preparation of polyurethane elastomer-based composites containing newly synthesized hybrid fillers of CuO-ZrO₂ and ZnO-ZrO₂ type. The idea behind the selection of materials was dictated by the mechanical durability of ZrO₂ as well antimicrobial activity of ZnO and CuO. The first stage of experimental approach included synthesis of hybrid fillers utilizing a modified sol-gel method which enables the formation of materials with expected chemical composition, unique morphological and structural characteristic as confirmed by micrometric-sized particles and parameters of the porous structure (A_BET = 260 m²/g, V_p = 0.24 cm³/g, S_p = 4.7 nm for CuO-ZrO₂ and A_BET = 210 m²/g, V_p = 0.12 cm³/g, S_p = 4.6 nm for ZnO-ZrO₂). Polyurethane-based composites were synthesized using a one-step method under variable parameters such as filler type and its percentage contribution. Such an assumption allowed to evaluate the impact of fillers addition on polyurethane composites functional properties. Detailed materials characterization confirmed that the prepared composites (especially those containing 5.0 wt% of CuO-ZrO₂) exhibit enhanced mechanical properties with reduction of abrasion by approximately 22 %, an increase of maximum stress by 27 % and an improvement in breaking strength by as much as 156 % compared to the reference sample – which should be considered as an outstanding result. The final stage included antimicrobial tests that confirmed high microbiological purity and antimicrobial activity of composites at the point of contact. Demonstrated antimicrobial properties are of utilitarian nature and provide a perspective for a possible extension of the durability and multi-directional usefulness of products consisting of such materials.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"216 ","pages":"Article 106453"},"PeriodicalIF":5.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144908291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functionalized polymer & metal oxide nanocomposite material for efficiency antibacterial and photocatalytic applications","authors":"Davronbek Bekchanov ,&nbsp;Davron Eshtursunov ,&nbsp;Arofat Inkhonova ,&nbsp;Mukhtarjan Mukhamediev ,&nbsp;Olim Ruzimuradov ,&nbsp;Dmitry Kovalenko ,&nbsp;Changhua An ,&nbsp;Xintai Su ,&nbsp;Peter Lieberzeit","doi":"10.1016/j.reactfunctpolym.2025.106457","DOIUrl":"10.1016/j.reactfunctpolym.2025.106457","url":null,"abstract":"<div><div>Functionalized polymer&amp;metal oxide nanocomposite materials are distinguished by their multifunctional properties. In this work, for the synthesis of a functional polymer-metal oxide nanocomposite material, polyvinyl chloride (PVC) was first modified with polyethyleneimine (PEI) under heterogeneous conditions. After amination, the Cu (II) ions were adsorbed onto anion-exchange (PPE-4) material. The resulting polymer/metal complex was then thermally treated to synthesize a functional nanocomposite CuO&amp;PPE-4 material containing copper oxide nanoparticles on the polymer surface. Synthesized functional CuO<em>&amp;</em>PPE-4 nanocomposite material was characterized using UV–Vis, PL, FTIR, Raman, XRD, SEM-EDX, and BET surface analysis to identification its structure, morphology, and physico-chemical properties. The antibacterial activity was tested against <em>Escherichia coli (E.coli</em>) and <em>Pseudomonas aeruginosa (P. aeruginosa</em>) for Gram-negative as well as <em>Staphylococcus aureus</em> (<em>S. aureus</em>) for Gram-positive bacteriums. Revealing a 26 <strong>±</strong> 0.5 mm inhibition zone for <em>E. coli,</em> 35 ± 0.5 mm for <em>P. aeruginosa</em> and 21 ± 0.5 mm <em>S. aureus</em> which significantly exceeded that of Cu²⁺<em>&amp;</em>PPE-4 due to enhanced reactive oxygen species (ROS) generation and improved charge separation. Moreover, the photocatalytic degradation of the functional CuO<em>&amp;</em>PPE-4 material of tetracycline (TC) was evaluated under sunlight degradation. UV–Vis spectroscopy confirmed a progressive decline in TC absorbance at 276 nm and 358 nm, indicating effective photocatalysis. The process followed pseudo-first-order kinetics, with rate constants of 1.01685 min⁻¹ (5 mg/L TC), 0.90951 min⁻¹ (10 mg/L), and 0.48637 min⁻¹ (20 mg/L). Possible reaction pathways for the photocatalytic degradation of TC are presented based on HPLC MS analysis. The functionalized CuO&amp;PPE-4 nanocomposite material synthesized at 150 °C exhibited a low band gap of 1.53 eV than other materials, which ensured effective photocatalytic and antibacterial activities. Furthermore, practical results show that the functionalized CuO&amp;PPE-4 nanocomposite material removes TC very effectively from pharmaceutical industry wastewater.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"216 ","pages":"Article 106457"},"PeriodicalIF":5.1,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144888772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progressive transpose from 3D to 4D printed materials for drug delivery and biomedical applications","authors":"Mansi Sharma ,&nbsp;Sunil Kumar Sah ,&nbsp;Subhadeep Roy ,&nbsp;Santanu Kaity","doi":"10.1016/j.reactfunctpolym.2025.106455","DOIUrl":"10.1016/j.reactfunctpolym.2025.106455","url":null,"abstract":"<div><div>Four-dimensional (4D) printing is emerging as a cutting-edge area of research in the field of drug delivery and biomedical applications. Since its initial conception in 2013, 4D printing has drawn much interest. 4D printing is the next evolutionary step made possible by the advances made in biomedical research with three-dimensional (3D) printing. This technology integrates smart materials into additive manufacturing to create constructs that can change shape or functionality over time in response to specific external, non-mechanical stimuli, such as moisture, temperature, light, pH, and magnetic fields. 4D-printed structures can exhibit dynamic behaviours including flexibility, self-folding, self-healing, expansion, and controlled deformation. The advantages of 4D printing mainly include enhanced ability to print, improved productivity in manufacturing, enhanced quality, and the opportunity to create a more extensive variety of items. 4D printing has made use of a variety of raw materials, including shape-memory polymers (SMPs), shape-memory hydrogels (SMHs), shape-memory polymer composites (SMPCs), shape-memory ceramics (SMCrs), and liquid crystal elastomers (LCEs). In order to provide a better outlook for 4D printing applications in the future, this review attempts to highlight the most current uses of smart materials and 4D printing technology in drug delivery, tissue engineering, smart implants, etc. Artificial intravesicular implants for bladder problems, microneedles to repair tissue wounds, ulcer-treating hydrogel capsules, and delivery of anticancer drugs using theragrippers are current instances of advancements in the clinical field using 4D printing. Herein, a detailed overview and the main challenges with this technology are discussed, along with recommendations for further research to overcome current constraints.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"216 ","pages":"Article 106455"},"PeriodicalIF":5.1,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144888713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ion liquid selective depolymerization of epoxy resin insulation materials from electric power industry in a polar aprotic solvent system","authors":"Lei Zhang ,&nbsp;Ruixue Wang ,&nbsp;Zuxian Dai ,&nbsp;Chenglong Zhang","doi":"10.1016/j.reactfunctpolym.2025.106456","DOIUrl":"10.1016/j.reactfunctpolym.2025.106456","url":null,"abstract":"<div><div>Growing interest has been shown in environmentally friendly, cost-effective methods for recovering and reusing glass fiber-reinforced epoxy resin composites. An efficient strategy was developed for chemical recycling of cured epoxy resin from retired composite insulator mandrel using 1-ethyl-3-methylimidazole acetate ([Emim][OAc])/dimethyl sulfoxide (DMSO) as the depolymerization system. Epoxy resin with chain structure could be recovered with water as precipitant. The process became more affordable and sustainable by eliminating water and then reusing reaction solvent. The resin products' fourier transform infrared spectroscopy (FTIR) and hydrogen nuclear magnetic resonance (HNMR) analysis before and following the decomposition process revealed that the cured crosslink segments (ester group) of epoxy resins could be selectively destroyed. The density functional theory (DFT) illustrated that the solvation effect of DMSO weakened the electrostatic interaction between [OAc]⁻ and [Emim]⁺, which was significantly more conducive to the nucleophilic addition of imidazole cation. Furthermore, it was proposed to control the selective breaking process of the epoxy resin cured crosslinked ester group by nitrogen heterocyclic carbene reaction, and further esterification to obtain regenerated resin containing ester carbonyl. This recovery process opened up a sustainable path with high atom economy. Retaining of epoxy chain structure was conducive to subsequent secondary curing recovery, and the reaction system could be reused many times.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"216 ","pages":"Article 106456"},"PeriodicalIF":5.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144888712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a polymer inclusion film incorporating a 1-dodecanol–decanoic acid eutectic mixture for the extraction of Dy3+ and Y3+","authors":"Charles F. Croft ,&nbsp;Tsveta Sarafska ,&nbsp;Tony G. Spassov ,&nbsp;Spas D. Kolev","doi":"10.1016/j.reactfunctpolym.2025.106454","DOIUrl":"10.1016/j.reactfunctpolym.2025.106454","url":null,"abstract":"<div><div>The extraction of the rare earth element (REE) ions Dy³⁺ and Y³⁺ by a polymer inclusion film (PIF), composed of poly(vinylidene fluoride-<em>co</em>-hexafluoropropylene) as the base polymer, decanoic acid (DA) as the extractant and 1-dodecanol (DD) as a modifier, was investigated. After observing that combining DA and DD formed a liquid at room temperature, the thermal properties of this mixture were studied using temperature modulated differential scanning calorimetry. The phase diagram of this binary system showed a eutectic composition of approximately 70 %(m/m) DD and 30 %(m/m) DA and a peritectic point at approximately 40 %(m/m) DD and 60 %(m/m) DA. It was also established that compositions with mass ratios of DD:DA in the range 40:60 − 80:20 remained liquid at temperatures above 20 °C, thus making them suitable for use as liquid phases in PIFs. Extraction experiments of Dy³⁺ into PIFs containing 60 %(m/m) film liquid phase with mass ratios of DD:DA in the range 20:40 − 40:20 did not show significant differences in the rate of Dy³⁺ extraction despite the significant variation in the extractant (DA) concentration. Selective extraction of Dy³⁺ over Y³⁺ was demonstrated, indicating the potential applicability of the abovementioned PIFs for the separation of these REE ions.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"216 ","pages":"Article 106454"},"PeriodicalIF":5.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144895453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic and bioactive self-healing PVA-based hydrogels containing Fe3O4/hydroxyapatite/bioglass: Physicochemical, mechanical, and in vitro biological assessments","authors":"Sahand Zabih Gholami ,&nbsp;Erfan Behjat ,&nbsp;Mohammadamir Hamzehlouei ,&nbsp;Ghazal Kadkhodaie Kashani ,&nbsp;Reza Gholami ,&nbsp;Seyed Morteza Naghib ,&nbsp;Hamid Reza Rezaie ,&nbsp;Maryam Tajabadi","doi":"10.1016/j.reactfunctpolym.2025.106446","DOIUrl":"10.1016/j.reactfunctpolym.2025.106446","url":null,"abstract":"<div><div>This study introduces a novel self-healing polyvinyl alcohol-based hydrogel cross-linked with borax and tannic acid, incorporating magnetite nanoparticles (MNPs), hydroxyapatite nanoparticles (HANPs), and Zn-, Mn-, and Ag-doped bioactive glass nanoparticles (BGNPs). Structural analyses (XRD, FTIR) confirmed successful synthesis, and SEM characterized the morphology. The hydrogel exhibited superparamagnetic behavior, with higher MNP concentrations inducing hyperthermia under an alternating magnetic field, raising temperatures by up to 12 °C. The optimal formulation demonstrated high swelling capacity (711 %), a Young's modulus of 280 kPa, and toughness of 3250 kJ/cm³, emphasizing its suitability for bone regeneration. Bioactivity studies revealed hydroxyapatite formation in simulated body fluid, confirming bone-bonding potential. The hydrogel achieved 40 % self-healing efficiency in tensile strength and enhanced cell proliferation in cytotoxicity assays. Antimicrobial tests showed effectiveness against gram-positive and gram-negative bacteria. These features establish this hydrogel as a dynamic biomaterial for advanced bone-related therapies and engineering applications.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"216 ","pages":"Article 106446"},"PeriodicalIF":5.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144895955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}