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Recenti progressi in medicina最新文献

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[Artificial intelligence for italian medicine: navigating between innovation and practice.] 意大利医学的人工智能：在创新与实践之间导航。
Recenti progressi in medicina Pub Date : 2025-10-01 DOI: 10.1701/4573.45773
Francesco Baglivo, Diana Ferro, Giacomo Diedenhofen
{"title":"[Artificial intelligence for italian medicine: navigating between innovation and practice.]","authors":"Francesco Baglivo, Diana Ferro, Giacomo Diedenhofen","doi":"10.1701/4573.45773","DOIUrl":"https://doi.org/10.1701/4573.45773","url":null,"abstract":"<p><p>\"Artificial intelligence is transforming healthcare\": this sentence is now so common it risks losing meaning. Technology alone does not change systems, people do: clinicians, researchers, decision-makers, and patients. AI is a lever, but without a fulcrum of skills, vision, and responsibility, it moves nothing. This conviction is at the core of the Italian Society for Artificial Intelligence in Medicine (SIIAM) and of the 3rd Annual Meeting (Naples, October 10-11, 2025). Our aim is not to celebrate technology for its own sake, but to bring together a multidisciplinary community capable of deciding how to use AI responsibly in the Italian healthcare system. This issue of Recenti Progressi in Medicina presents the collective output of this effort: commentaries by the Scientific Committee and contributions from participants. It is shown how rules and principles can be translated into practice, how Italian healthcare can evolve toward a Learning Health System, and why responsible infrastructures and evaluation frameworks are needed to guide AI innovation. Case studies highlight both promising advances and pitfalls to avoid. The central question is not whether AI will change medicine, but how we can use it to have a more equitable, proactive, sustainable and personalized one? If the lever is AI, the fulcrum remains the people and organizations who care for others. It is on this fulcrum that SIIAM continues to work, with rigor, openness, and trust, so that innovation becomes daily practice for the benefit of patients and professionals alike.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 10","pages":"543-545"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Federated Learning in neurologia: applicazioni nello stroke, malattia di Alzheimer e di Parkinson. 联合学习在神经病学中的应用：在中风、精神病、阿尔茨海默病和帕金森病中的应用。
Recenti progressi in medicina Pub Date : 2025-10-01 DOI: 10.1701/4573.45790
Cosimo Guerra, Rosario De Feo
{"title":"Federated Learning in neurologia: applicazioni nello stroke, malattia di Alzheimer e di Parkinson.","authors":"Cosimo Guerra, Rosario De Feo","doi":"10.1701/4573.45790","DOIUrl":"https://doi.org/10.1701/4573.45790","url":null,"abstract":"<p><p>AI is transforming neurology, providing powerful diagnostic and therapeutic tools, yet handling sensitive clinical data involves substantial privacy risks. Federated Learning addresses these issues by training models locally within hospitals and sharing only their weights or gradients for final training, achieving similar or superior performance compared to centralized models in Stroke, Alzheimer's, and Parkinson's disease.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 10","pages":"591-592"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Care-Vax: integrazione digitale ospedale-territorio per la tutela dei pazienti fragili e il potenziamento della copertura vaccinale secondo i principi della value-based healthcare. Care-Vax:医院和地区的数字整合，以保护脆弱的病人，并根据基于价值观念的护理原则加强疫苗接种覆盖面。
Recenti progressi in medicina Pub Date : 2025-10-01 DOI: 10.1701/4573.45803
Donato Cocolicchio, Vittorio De Vita, Felicia Cuoco, Diego Tona, Martina Porcelli, Daniele Postorino, Francesca Scaglioso, Domenico Pascucci, Luca Regazzi, Roberta Pastorino, Patrizia Laurenti
{"title":"Care-Vax: integrazione digitale ospedale-territorio per la tutela dei pazienti fragili e il potenziamento della copertura vaccinale secondo i principi della value-based healthcare.","authors":"Donato Cocolicchio, Vittorio De Vita, Felicia Cuoco, Diego Tona, Martina Porcelli, Daniele Postorino, Francesca Scaglioso, Domenico Pascucci, Luca Regazzi, Roberta Pastorino, Patrizia Laurenti","doi":"10.1701/4573.45803","DOIUrl":"https://doi.org/10.1701/4573.45803","url":null,"abstract":"<p><p>The CareVax project aims to enhance vaccination coverage in fragile patients by creating digital pathways between hospitals and local health authorities. It utilizes an automated algorithm to identify eligible patients for vaccination based on electronic health records and regional vaccine registries. Expected outcomes include improved vaccination rates and a scalable technological model for digital public health.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 10","pages":"617-618"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuratezza e affidabilità di GPT-4 nel rispondere alle domande dei pazienti su malattie dermatologiche: uno studio sul ruolo dell’intelligenza artificiale nell’assistenza digitale ai pazienti. GPT-4在回答皮肤病患者的问题时的准确性和可靠性:一项关于人工智能在数字病人护理中的作用的研究。
Recenti progressi in medicina Pub Date : 2025-10-01 DOI: 10.1701/4573.45793
Tiziana Pinciroli, Luigi De Angelis, Francesco Andrea Causio, Antonio Iacuzio, Vittorio Grieco, Emanuele Agrimi, Francesco Traglia, Maria Rosa Valetto, Pietro Dri, Luigi Naldi
{"title":"Accuratezza e affidabilità di GPT-4 nel rispondere alle domande dei pazienti su malattie dermatologiche: uno studio sul ruolo dell’intelligenza artificiale nell’assistenza digitale ai pazienti.","authors":"Tiziana Pinciroli, Luigi De Angelis, Francesco Andrea Causio, Antonio Iacuzio, Vittorio Grieco, Emanuele Agrimi, Francesco Traglia, Maria Rosa Valetto, Pietro Dri, Luigi Naldi","doi":"10.1701/4573.45793","DOIUrl":"https://doi.org/10.1701/4573.45793","url":null,"abstract":"<p><p>Using large language models (LLMs) to answer patients' questions is promising but calls for caution and careful validation. We assessed GPT-4o mini-generated answers to dermatology-related patient questions and compared them to specialists' answers. While GPT-4o mini provided clearer and more updated information, some answers contained inaccuracies that could lead to risky patient management. Future work should explore retrieval techniques from reliable sources to enhance safety and accuracy.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 10","pages":"597-598"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Requisiti tecnici minimi per interfacce IA in medicina: un framework per usabilità e trasparenza. 医学中人工智能接口的最低技术要求:可用性和透明度的框架。
Recenti progressi in medicina Pub Date : 2025-10-01 DOI: 10.1701/4573.45792
Florinda Coro, Alice Ravizza, Amedeo Franco Bonatti, Carmelo De Maria, Giovanni Vozzi
{"title":"Requisiti tecnici minimi per interfacce IA in medicina: un framework per usabilità e trasparenza.","authors":"Florinda Coro, Alice Ravizza, Amedeo Franco Bonatti, Carmelo De Maria, Giovanni Vozzi","doi":"10.1701/4573.45792","DOIUrl":"https://doi.org/10.1701/4573.45792","url":null,"abstract":"<p><p>The use of artificial intelligence in medicine requires software user interfaces that ensure usability, transparency, and compliance with the European AI Act. The proposed framework defines minimum technical requirements for each usage phase, from data input to model interpretation, promoting safety, explainability, and human oversight, elements still underdeveloped in clinical practice.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 10","pages":"595-596"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Molecular diagnostics of thyroid nodule]. 甲状腺结节的分子诊断。
Recenti progressi in medicina Pub Date : 2025-09-01 DOI: 10.1701/4556.45573
Domenico Rocco, Anna Tortora, Vincenzo Marotta, Mario Vitale
{"title":"[Molecular diagnostics of thyroid nodule].","authors":"Domenico Rocco, Anna Tortora, Vincenzo Marotta, Mario Vitale","doi":"10.1701/4556.45573","DOIUrl":"https://doi.org/10.1701/4556.45573","url":null,"abstract":"<p><p>Nodular goiter is a very frequent occurrence that rarely requires surgical treatments. Only a few of these nodules are the site of carcinoma which requires surgery. It is therefore necessary to precisely determine the nature of the nodule. The cytological examination of the biopsy performed with a fine needle is the most accurate diagnostic method for determining the benign or malignant nature of a thyroid nodule. However, in approximately 15% of cases the cytology is indeterminate. In these cases, it is possible to apply the knowledge of molecular biology to refine the diagnosis. Mutations of the BRAF and RAS genes and recombinations of the RET, TRK and PAX8/PPARγ genes are the most frequent genetic alterations in thyroid carcinomas. However, except for BRAF mutation, these genetic alterations are not pathognomonic of carcinoma. The new tests that combine the gene expression profile and the search for specific genetic alterations have excellent reliability in excluding the malignant nature of a nodule with indeterminate cytology, but they still have an unsatisfactory specificity, and their cost limits their use.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"502-505"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[It is better not to use injections or radiofrequency to treat non-cancer-related chronic low back or neck pain]. [最好不要使用注射或射频治疗非癌症相关的慢性腰痛或颈部疼痛]。
Recenti progressi in medicina Pub Date : 2025-09-01 DOI: 10.1701/4556.45577
Alice Serafini, Allen F Shaughnessy
{"title":"[It is better not to use injections or radiofrequency to treat non-cancer-related chronic low back or neck pain].","authors":"Alice Serafini, Allen F Shaughnessy","doi":"10.1701/4556.45577","DOIUrl":"https://doi.org/10.1701/4556.45577","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"524-525"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Duloxetine, milnacipran, and pregabalin significantly reduce pain in adults with fibromyalgia]. [度洛西汀、米那西普兰和普瑞巴林可显著减轻成人纤维肌痛患者的疼痛]。
Recenti progressi in medicina Pub Date : 2025-09-01 DOI: 10.1701/4556.45579
Peter K Kurotschka, Henry Barry
{"title":"[Duloxetine, milnacipran, and pregabalin significantly reduce pain in adults with fibromyalgia].","authors":"Peter K Kurotschka, Henry Barry","doi":"10.1701/4556.45579","DOIUrl":"https://doi.org/10.1701/4556.45579","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"528-529"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The alliance of cybersecurity and artificial intelligence in digital healthcare: challenges and solutions from the EU CYLCOMED RWD project]. [数字医疗中的网络安全和人工智能联盟：来自欧盟CYLCOMED RWD项目的挑战和解决方案]。
Recenti progressi in medicina Pub Date : 2025-09-01 DOI: 10.1701/4556.45571
Alberto Eugenio Tozzi, Ileana Croci, Ginevra Campia, Diana Ferro
{"title":"[The alliance of cybersecurity and artificial intelligence in digital healthcare: challenges and solutions from the EU CYLCOMED RWD project].","authors":"Alberto Eugenio Tozzi, Ileana Croci, Ginevra Campia, Diana Ferro","doi":"10.1701/4556.45571","DOIUrl":"https://doi.org/10.1701/4556.45571","url":null,"abstract":"<p><p>The availability of health technologies has facilitated improvements in the quality of care, playing a vital role in both hospital environments and remote patient monitoring. However, the growing complexity of these technologies has also led to an increase in cyberattacks targeting healthcare systems over time. The CYLCOMED project was initiated to create cybersecurity solutions for connected health devices, testing them in two scenarios: first, protecting the security of a drug infusion pump; and second, monitoring pediatric patients with heart failure remotely. The project employs a combination of software and artificial intelligence (AI) algorithms to detect cybersecurity threats by overseeing the operation of connected devices in these case studies. Additionally, it addresses regulatory and ethical considerations to develop an AI-driven product suitable for clinical implementation. Integrating advanced technological tools, cybersecurity awareness, and preventive strategies is essential for ensuring patient safety.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"489-496"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Healthcare at a crossroads: ethical decisions or collapse]. [十字路口的医疗保健：道德决策或崩溃]。
Recenti progressi in medicina Pub Date : 2025-09-01 DOI: 10.1701/4556.45570
Vittorio Franciosi
{"title":"[Healthcare at a crossroads: ethical decisions or collapse].","authors":"Vittorio Franciosi","doi":"10.1701/4556.45570","DOIUrl":"https://doi.org/10.1701/4556.45570","url":null,"abstract":"<p><p>In 1948, Aneurin Bevan launched the UK's National Health Service (NHS), emphasizing health as a right. Inspired by this, Italy created its NHS in 1978, based on universality and equity. Despite efforts focusing on clinical efficacy and economic efficiency, Italy's NHS faces a crisis: uncontrolled public spending, rising private costs, neglect of prevention, staff shortages, long wait times and regional disparities in care. Inefficiencies include overuse of ineffective treatments, underuse of effective ones, high costs, and conflicts of interest. Aging, chronic diseases, and lifestyle issues also impact healthcare use. Medical and managerial criteria alone can't justify healthcare choices, as they don't address how resources should be distributed across sectors or prioritize patient groups. Donald Berwick advocates for an ethical approach focused on justice, prioritizing care quality, fairness, transparency, and compassion. Daniel Callahan and others call for a cultural revolution in medicine, advocating a \"limited\" healthcare role, moving away from individualism, and fostering a realistic understanding of health. Without ethical principles, healthcare reform may fail.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"485-488"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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