Recenti progressi in medicina最新文献

{"title":"Reactivating experience: reintegrating retired oncologists into the healthcare system. The point of view of a young oncologist.","authors":"Margherita Ratti","doi":"10.1701/4556.45569","DOIUrl":"https://doi.org/10.1701/4556.45569","url":null,"abstract":"<p><p>This editorial discusses the national survey, by Barni et al., which examines the lives of retired medical oncology chiefs in Italy, focusing on their well-being, ongoing professional identity, and willingness to remain engaged in the healthcare system. In a time of critical workforce shortages in oncology, the findings reveal a valuable yet underutilized resource: retired physicians.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"483-484"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La curva del Latte.","authors":"Fabio De Iaco","doi":"10.1701/4556.45581","DOIUrl":"https://doi.org/10.1701/4556.45581","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"536"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Acute migraine treatment: navigating and comparing available therapies].","authors":"Viviana Forte, Allen F Shaughnessy","doi":"10.1701/4556.45576","DOIUrl":"https://doi.org/10.1701/4556.45576","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"522-523"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Polatuzumab vedotin in the treatment of relapsed or refractory DLBCL: a case report].","authors":"Daniele Contin, Roberto Sartori, Sara Berti, Alida Sartorello, Carlo Giovanni Doroldi","doi":"10.1701/4556.45580","DOIUrl":"https://doi.org/10.1701/4556.45580","url":null,"abstract":"<p><p>Diffuse large B-cell lymphomas (DLBCLs) represent one of the most common and aggressive forms of non-Hodgkin lymphoma (NHL), characterized by rapid B-cell growth and a significantly high risk of relapse or refractoriness. The clinical course for these patients is long and complicated with a sometimes dismal prognosis, and the therapeutic approach must include effective and innovative chemotherapeutic treatments. The therapeutic strategies for DLBCLs in recent years has seen considerable pharmacological enrichment, including drug-conjugated antibodies such as polatuzumab vedotin. Indeed, this drug has demonstrated its efficacy even in the age-unfit elderly patient, providing a good safety and tolerability profile. Specifically, is described the case of an elderly patient with relapsed/refractory DLBCL with extra-nodal and bone disease presentation, treated second-line with polatuzumab vedotin in combination with rituximab and bendamustine. This combination resulted in a complete clinical and metabolic response while preserving excellent drug tolerance during treatment and improving the patient's quality of life.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"530-535"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Redefining the disease: between the risk of medicalization and the urgency of training].","authors":"Luca De Fiore, Camilla Alderighi, Raffaele Rasoini","doi":"10.1701/4556.45567","DOIUrl":"10.1701/4556.45567","url":null,"abstract":"<p><p>The definition of disease is not a purely theoretical exercise but a choice with significant implications for clinical practice, public health, and resource management. The expansion of diagnostic criteria, aimed at reducing underdiagnosis, has led to an increase in overdiagnosis and overtreatment - critical issues still too little addressed in medical education and public communication.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"479-480"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Tinnitus may improve with sound masking techniques, cognitive behavioral therapy and patient education].","authors":"Daniele Ferrari, Allen F Shaughnessy","doi":"10.1701/4556.45578","DOIUrl":"https://doi.org/10.1701/4556.45578","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"526-527"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recensione.<br>“Cartella clinica”.","authors":"","doi":"10.1701/4556.45582","DOIUrl":"https://doi.org/10.1701/4556.45582","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"537"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dalla letteratura<br> 2025 Settembre.","authors":"","doi":"10.1701/4556.45566","DOIUrl":"https://doi.org/10.1701/4556.45566","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"475-478"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caesarean section rate trend in the Calabria Region according to Robson's Ten Group Classification System: a population-based study.","authors":"Francesca Zambri, Edoardo Corsi Decenti, Alice Maraschini, Jessica Preziosi, Gabriella Tambascia, Vincenza Di Stefano, Francesca Marchetti, Caterina Azzarito, Daniela Lico, Serena Donati, Anna Domenica Mignuoli, Roberta Venturella, Angela Giusti","doi":"10.1701/4556.45575","DOIUrl":"10.1701/4556.45575","url":null,"abstract":"<p><strong>Background: </strong>The global increase in caesarean section (CS) rates raises concerns about maternal and neonatal outcomes. Italy, with one of the highest CS rates in Europe, especially in the Calabria Region, faces challenges in reducing this trend. The Calabria Region has joined the \"Easy-Net\" Network Program (NET-2016-02364191) for the evaluation of audit & feedback (A&F) interventions to reduce CS rate. This study aims to analyze past trends, describe maternity unit (MU) characteristics, and provide a baseline assessment of CS rates using the Robson's Ten Group Classification System (TGCS).</p><p><strong>Methods: </strong>This population-based cross-sectional study analyses CS rates using data from National and Regional Birth Registers, categorizing women with the Robson's TGCS.</p><p><strong>Results: </strong>From 2017 to 2020, 54,041 births were registered in the Calabria Region. The results reveal a fluctuating CS rate (36.2%-38.1%) with variations from different Robson groups. Group 5 (previous CS) consistently increased, impacting overall rates, while Group 1 (nulliparous, cephalic, spontaneous labor) decreased. The groups 2b (6.8%-4.8%) and 4b (2.5%-1.8%), which represent respectively nulliparous and multiparous women with pre-labour CS, showed high rates despite their reduction over the years. In 2020, variations in CS rates across 11 MUs highlighted complexities, emphasizing the need for localized interventions.</p><p><strong>Conclusions: </strong>The study highlights the critical issue of high CS rates in the Calabria Region. It is advisable to monitor and reduce unnecessary CSs through evidence-based interventions, taking advantage of the Robson classification and an A&F strategy. These findings guide future efforts to enhance CS appropriateness and improve maternal and child health outcomes.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"513-521"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compassionate use of medicinal products: a comparison between the European and the United States of America regulatory frameworks.","authors":"Arianna Orcesi, Evelina Cattadori, Pilade Cortellazzi, Corrado Confalonieri","doi":"10.1701/4556.45572","DOIUrl":"https://doi.org/10.1701/4556.45572","url":null,"abstract":"<p><p>The treatment of patients suffering from chronic, potentially lethal diseases is a lengthy and disheartening process, especially in cases where patients cannot be satisfactorily treated with authorized medications. In these cases, the only therapeutic option may be experimental drugs. However, in some cases, not all patients meet the inclusion criteria for enrollment in a trial. This problem can be addressed through a \"compassionate use\". Because inadequate information can be a barrier it is essential to clarify the regulatory framework. Despite the availability of reviews, information available on this topic is limited also due to changes in regulations that occur over time. Moreover, the different definitions between states and the lack of a common legislative approach makes the process confusing. The purpose of this article is to compare the legislative frameworks currently in place in European Union and Usa pharmaceutical markets, in order to highlight their strengths, analogies and differences, in a global context that goes beyond the regulatory realities of individual countries.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 9","pages":"497-501"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}