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[Appendix ... it's not just appendicitis: neuroendocrine tumors.] [阑尾......不仅仅是阑尾炎：神经内分泌肿瘤]。
Recenti progressi in medicina Pub Date : 2024-07-01 DOI: 10.1701/4314.42991
Martina Mainetti, Maria Rosaria Aprile, Davide Campana, Federico Marchetti
{"title":"[Appendix ... it's not just appendicitis: neuroendocrine tumors.]","authors":"Martina Mainetti, Maria Rosaria Aprile, Davide Campana, Federico Marchetti","doi":"10.1701/4314.42991","DOIUrl":"10.1701/4314.42991","url":null,"abstract":"<p><p>Well-differentiated neuroendocrine tumors of the appendix (NETs) are rare in pediatric and adolescent age groups. However, they are the most common gastrointestinal epithelial tumor in this age group and the most common malignancy of the appendix in the general population. The classification of these tumors considers factors such as the proliferation index, size of the neoplasm, and the presence of perineural and/or lymphovascular invasion, which can contribute to distant metastases. Preoperative diagnosis is challenging, except in cases where patients exhibit symptoms of carcinoid syndrome or signs of metastatic disease, which are uncommon in pediatric and adolescent patients. For tumors smaller than 1 cm, appendectomy is usually curative, while larger tumors or those at risk of spreading may require right hemicolectomy with lymphadenectomy. We present a case of an adolescent with NET and provide a literature review on the diagnostic and therapeutic approaches that should be considered for this relatively rare condition.Key words. Adolescent age, appendix, neuroendocrine tumors, pediatric age.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Can citizenship help analyze the risk of underimmunization in the foreign population?] [公民身份有助于分析外国人口免疫接种不足的风险吗？］
Recenti progressi in medicina Pub Date : 2024-07-01 DOI: 10.1701/4314.42984
Chiara Primieri, Carla Bietta
{"title":"[Can citizenship help analyze the risk of underimmunization in the foreign population?]","authors":"Chiara Primieri, Carla Bietta","doi":"10.1701/4314.42984","DOIUrl":"10.1701/4314.42984","url":null,"abstract":"<p><p>There is emerging evidence of distrustful attitudes towards vaccination of some sub-populations of migrants in Europe, that are at higher risk for under-immunisation. The Covid-19 pandemic has highlighted health disparities also at a national level: lower levels of Covid-19 vaccine uptake in immigrants' population compared with Italian citizens and a substantial heterogeneity in the first-dose vaccine coverage within immigrants' population have been documented. According to immigrants' citizenship, high coverages were observed in subjects from Southeast Asia and from South-Central America while Eastern Europeans showed the lowest coverages. These data suggest that taking into account immigrants' citizenship can help define appropriate strategies in order to promote a personalized approach to health problems and to strengthen vaccination uptake.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recensioni.
"Il valore della ricerca. Storie ed eccellenze dell'Istituto Mario Negri"
"Disfunzioni vegetative"
di Stefano Cagliano. 评论："研究的价值。马里奥-奈格里研究所的故事和卓越成就""植物功能障碍"，斯特凡诺-卡利亚诺著。
Recenti progressi in medicina Pub Date : 2024-07-01 DOI: 10.1701/4314.42994
{"title":"Recensioni.<br>\"Il valore della ricerca. Storie ed eccellenze dell'Istituto Mario Negri\"<br>\"Disfunzioni vegetative\"<br>di Stefano Cagliano.","authors":"","doi":"10.1701/4314.42994","DOIUrl":"https://doi.org/10.1701/4314.42994","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The physical activity paradox.] [体育锻炼悖论]
Recenti progressi in medicina Pub Date : 2024-07-01 DOI: 10.1701/4314.42985
Matteo Franco, Fulvio Ricceri
{"title":"[The physical activity paradox.]","authors":"Matteo Franco, Fulvio Ricceri","doi":"10.1701/4314.42985","DOIUrl":"10.1701/4314.42985","url":null,"abstract":"<p><p>Recent discoveries have shown that the effects of physical activity on health are not the same in all its domains. In particular, the health effects of physical activity differ not only in terms of modality and intensity, but also based on the context in which it is carried out. Several studies have observed that those who do a lot of physical activity at work tend to have worse health outcomes than those who do less physical activity at work but more exercise in their free time. This phenomenon has been defined as the \"physical activity paradox\". However, it is worth reporting that differences in health outcomes have been observed for different socioeconomic positions and that more favorable socioeconomic positions tend to have healthier lifestyles.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Lighthouse keeper syndrome: update.] [灯塔看守人综合症：更新]
Recenti progressi in medicina Pub Date : 2024-07-01 DOI: 10.1701/4314.42986
Giuseppe Fatati
{"title":"[Lighthouse keeper syndrome: update.]","authors":"Giuseppe Fatati","doi":"10.1701/4314.42986","DOIUrl":"10.1701/4314.42986","url":null,"abstract":"<p><p>A few years ago, with the expression \"lighthouse keeper syndrome\", we identified those who showed exceptional attention to the control of eating and body weight. Recently the same term was used to describe, at the end of the lockdown, the feeling of living with fear the encounter with external reality, which for many weeks remained confined outside our homes. We are of the opinion that the lighthouse keeper syndrome includes all those behaviors characterized by voluntary, even if often unconscious, social isolation and by the exasperated search for absolute dominion over a single aspect of our being. There are two types of social isolation, the static one typical of those who spend their time closed at home (hikikomori) and the dynamic one characteristic of those who go out, walk but do not interact with other individuals. The radicalization of some food trends can lead to convivial group social isolation. The changes in the characteristic clinical manifestations of lighthouse keeper syndrome demonstrate the impact of society and culture on the individual psychopathology.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Survey on maintenance immunosuppressive therapy in patients undergoing solid organ transplantation: experiences from Italian transplant centers.] [关于接受实体器官移植患者的维持性免疫抑制疗法的调查：意大利移植中心的经验]。
Recenti progressi in medicina Pub Date : 2024-07-01 DOI: 10.1701/4314.42988
Arianna Bellini, Alessandro C Rosa, Stefania Spila Alegiani, Marco Massari, Lucia Masiero, Marco Finocchietti, Claudia Marino, Nera Agabiti, Massimo Cardillo, Nicoletta Luxi, Gianluca Trifirò, Pamela Fiaschetti, Marina Davoli, Antonio Addis, Valeria Belleudi
{"title":"[Survey on maintenance immunosuppressive therapy in patients undergoing solid organ transplantation: experiences from Italian transplant centers.]","authors":"Arianna Bellini, Alessandro C Rosa, Stefania Spila Alegiani, Marco Massari, Lucia Masiero, Marco Finocchietti, Claudia Marino, Nera Agabiti, Massimo Cardillo, Nicoletta Luxi, Gianluca Trifirò, Pamela Fiaschetti, Marina Davoli, Antonio Addis, Valeria Belleudi","doi":"10.1701/4314.42988","DOIUrl":"10.1701/4314.42988","url":null,"abstract":"<p><p>The post-organ transplant immunosuppressive therapy includes the administration of tacrolimus (Tac) or cyclosporine (CsA), along with antimetabolites (Antim) or mTOR inhibitors, with or without prednisone. A survey was conducted to investigate clinical experience regarding the use, efficacy, safety profile, and determinants of choice of maintenance immunosuppressive therapies. The questionnaire was sent to healthcare workers of 45 transplant centers specializing in kidney (K), liver (L), heart (H), and lung (P) transplants. Seventy-one responses were received from 15 Italian regions. The indicated first-choice therapy was Tac + Antim, except in the hepatic field where Tac monotherapy was favored. According to 44.1% of respondents, the first-choice therapy has changed over the last 15 years due to the replacement of CsA with Tac and increased use of mTOR inhibitors. Regarding the determinants of the index therapy, the choice of schemes to be applied depends mainly on international guidelines, previous experience, and internal protocols within the facility (80.3%; 54.9%; 50.7%, respectively). Compared to standard therapy, the criteria guiding the prescription of different therapies mainly involve the presence of comorbidities (K: 81.3%; L: 88.2%; H: 73.3%; P: 85.7%) and the evaluation of specific clinical parameters of the recipient. Additionally, the majority of respondents are in favor of using generic versions where available. The survey reveals dimensions not detectable by current healthcare administrative flows; such integrations provide a broader picture of the factors influencing the choice of post-transplant immunosuppressive therapeutic schemes.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Un mese nei tweet
per conoscere, per riflettere, per costruire reti. 在推特上学习、反思和建立网络的一个月。
Recenti progressi in medicina Pub Date : 2024-07-01 DOI: 10.1701/4314.42982
{"title":"Un mese nei tweet<br>per conoscere, per riflettere, per costruire reti.","authors":"","doi":"10.1701/4314.42982","DOIUrl":"https://doi.org/10.1701/4314.42982","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Top 4 Research Studies of the month for Italian Primary Care Physicians: June 2024.] [意大利初级保健医生本月的四大研究：2024 年 6 月]。
Recenti progressi in medicina Pub Date : 2024-07-01 DOI: 10.1701/4314.42990
Peter K Kurotschka, Alice Serafini, Allen Shaughnessy, Henry Barry, Mark H Ebell
{"title":"[Top 4 Research Studies of the month for Italian Primary Care Physicians: June 2024.]","authors":"Peter K Kurotschka, Alice Serafini, Allen Shaughnessy, Henry Barry, Mark H Ebell","doi":"10.1701/4314.42990","DOIUrl":"https://doi.org/10.1701/4314.42990","url":null,"abstract":"<p><p>This monthly article provides a collection of summaries of the most relevant studies identified as POEMs (patient-oriented evidence that matters) for Italian primary care physicians. 1) Although bleeding risk scores such as HAS-BLED and HEMORR2HAGE are widely recommended by guidelines for decision-making regarding long-term anticoagulation, their accuracy in primary care patients seems to be pretty terrible. Studies in the primary care setting that derive and then externally validate simple, pragmatic risk scores are needed. 2) Point-of-care ultrasound is increasingly finding a role at the bedside, and this study adds to that evidence base. In the patient with acute abdominal pain, point-of-care ultrasound has been shown to be highly accurate for diagnosis of appendicitis, small bowel obstruction, aneurysm - and now, acute diverticulitis. 3) According to a recent meta-analysis, rhythm control is associated with a lower risk of dementia and cognitive dysfunction than rate control. Most of the data come from middling quality studies, which likely overestimate the purported protective effects. 4) Limited quality research finds no difference in outcomes among common treatments for acute otitis externa, including antibiotic, steroid, antiseptic, or nonpharmacologic treatment. Given the low quality of trials conducted so far, it remains to be seen if larger, better studies will find out a difference, but for now the existing literature gives us little guidance.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In questo numero
2024 Luglio/Agosto. 本期内容2024 年 7 月/8 月。
Recenti progressi in medicina Pub Date : 2024-07-01 DOI: 10.1701/4314.42980
{"title":"In questo numero<br>2024 Luglio/Agosto.","authors":"","doi":"10.1701/4314.42980","DOIUrl":"https://doi.org/10.1701/4314.42980","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[An LLM for a friend.] [给朋友的法学硕士]
Recenti progressi in medicina Pub Date : 2024-07-01 DOI: 10.1701/4314.42983
Alberto Eugenio Tozzi
{"title":"[An LLM for a friend.]","authors":"Alberto Eugenio Tozzi","doi":"10.1701/4314.42983","DOIUrl":"10.1701/4314.42983","url":null,"abstract":"<p><p>The large language models (LLMs) represent a technology that has not yet seen widespread use. In addition to the automatic transcription of doctor-patient conversations, these tools will be able to support doctors in diagnosis and improve communication between doctors and patients. Their large-scale adoption is still limited due to concerns about sharing sensitive data, a lack of digital literacy, and the need to build new processes in clinical routines. To fully realize their potential, it is essential to train healthcare personnel on the functionalities of LLMs and to promote interdisciplinarity and scientific research, transforming artificial intelligence into augmented intelligence.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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