Recenti progressi in medicina最新文献

{"title":"[Primary prevention of stroke: the updated guidelines from the American Heart Association and the American College of Cardiology.]","authors":"Viviana Forte, Henry Barry","doi":"10.1701/4460.44560","DOIUrl":"https://doi.org/10.1701/4460.44560","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 3","pages":"189-190"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[To achieve significant weight loss, at least 150 minutes per week of moderate exercise are needed.]","authors":"Mario Luciano, David Slawson, Alice Serafini","doi":"10.1701/4460.44562","DOIUrl":"https://doi.org/10.1701/4460.44562","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 3","pages":"193-194"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluating the accuracy of large language models in answering mammography screening questions in Italian and English: a study based on the Eusobi guidelines.]","authors":"Manuel Signorini, Silvia Fontani, Paola Minichetti, Silvia Teggi, Alessandra Barusco, Massimo Favat","doi":"10.1701/4460.44556","DOIUrl":"https://doi.org/10.1701/4460.44556","url":null,"abstract":"<p><strong>Introduction: </strong>Artificial intelligence (AI) is transforming various aspects of everyday life, including healthcare, through large language models (LLMs) like ChatGPT, Gemini, and Copilot. These systems are increasingly used to disseminate medical information, allowing patients to access simplified explanations. This study aims to compare responses to breast imaging-related questions formulated in Italian and English, based on Eusobi guidelines, evaluating the LLMs' ability to provide accurate and complete answers on mammography screening concepts.</p><p><strong>Materials and methods: </strong>Nine questions related to breast cancer screening were developed by five breast radiologists based on Eusobi recommendations. These questions were submitted to ChatGPT, Gemini, and Copilot in both Italian and English. Responses were evaluated by two expert breast radiologists using a Likert scale (1 to 5), with statistical analysis performed to compare the accuracy, average length of responses, use of radiological sources and the agreement among readers.</p><p><strong>Results: </strong>The average scores for responses were similar in both languages, ranging from 3.6 to 4 out of 5. Questions on general mammography concepts received more accurate answers, while more specific questions based on the latest guidelines showed incomplete responses, especially about the definition of dense breast. The sources used, particularly in Italian, were often non-specialized in radiology, highlighting a limitation of LLMs in providing detailed and up-to-date medical answers.</p><p><strong>Conclusions: </strong>The study shows that LLMs are useful tools for medical communication, but they have limitations in delivering accurate answers on highly specialized medical topics. To improve the quality of information, collaboration between AI experts and healthcare professionals is necessary, especially in breast cancer prevention and screening.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 3","pages":"162-167"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dalla letteratura<br>2025 marzo.","authors":"","doi":"10.1701/4460.44550","DOIUrl":"https://doi.org/10.1701/4460.44550","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 3","pages":"131-136"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Numeri in questo numero<br>2025 marzo.","authors":"","doi":"10.1701/4460.44549","DOIUrl":"https://doi.org/10.1701/4460.44549","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 3","pages":"129"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategies in using artificial intelligence to combat antimicrobial resistance.","authors":"Andrea Zovi, Giacomo Polito, Andrea Caprodossi, Michela Sabbatucci, Rosario Sorrentino, Antonio Vitiello","doi":"10.1701/4460.44557","DOIUrl":"https://doi.org/10.1701/4460.44557","url":null,"abstract":"<p><p>Infectious diseases caused by pathogens resistant to antimicrobial treatments, defined as antimicrobial resistance (AMR), are a serious global health crisis, considered among the main threats to global public health according to the World Health Organization. New forms of advanced information technology are receiving global consideration as a help in countering this health threat, like Artificial Intelligence (AI). Applications of AI in healthcare could help in reducing the time needed to discover new antimicrobial drugs, improving the accuracy and timing of surveillance, diagnosis, and treatment, while reducing expenses. AI is now proposed as a valuable and potential help for different sectors of the health world. In this short review, we will consider the recent evidence supporting the important role that AI can play in countering the phenomenon of AMR.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 3","pages":"168-174"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[\"Kasomay\" can help the children of Casamance.]","authors":"Marcello Semprini","doi":"10.1701/4460.44552","DOIUrl":"https://doi.org/10.1701/4460.44552","url":null,"abstract":"<p><p>The Kasomay Association was founded in 2011 thanks to the work of a group of volunteers, mainly doctors and health care workers, with different experiences and professionalism. The place of election is the region of Casamance, in the south of Senegal. During missions we visit and treat children free of charge, pay for therapies and fund diagnostic and therapeutic pathways as well as hospitalizations and surgeries when needed. We have also developed a system for the management of health problems in the paediatric population, through which we aim to ensure continuous access to care for acute and chronic diseases and the management of emergencies and surgical interventions. This system was built within the local public health service and involves the collaboration of African health workers working on the territory.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 3","pages":"139-141"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[CAR-T cell therapy in a patient with relapsed/refractory mantle cell lymphoma.]","authors":"Virginia Naso, Filippo Canale, Giorgia Policastro, Gaetana Porto, Maria Pellicano, Massimo Martino","doi":"10.1701/4460.44570","DOIUrl":"https://doi.org/10.1701/4460.44570","url":null,"abstract":"<p><strong>Introduction: </strong>Mantle cell lymphoma (MCL) is one of the rarest forms of non-Hodgkin's lymphoma that mainly affects adults around 65 years of age or older, and is diagnosed when the disease has already reached a fairly advanced stage. Partly for this reason, but mainly because of the very characteristics of this rare form of lymphoma, the prognosis is often poor. In most cases, the disease recurs after a period of remission achieved with I-line. In the past decade, BTK inhibitors have become a mainstay of therapy for patients with relapsed/refractory mantle cell lymphoma. Although BTK inhibitors have improved the prognosis of relapsed/refractory mantle cell lymphoma, treatment options for patients who experience progression during or after BTK inhibitors remain limited. In this context, the development of anti-CD19 CAR T-cell therapy represents an important advance in the treatment of patients with chemorefractory MCL.</p><p><strong>Clinical case: </strong>We present the case of a 65-year-old man with diagnosis Mantle cell lymphoma MIPI intermediate risk, positive history only for hypertension, in disease progression during II-line therapy with Ibrutinib undertaken for relapse after of I-line polychemotherapy and consolidation with autologous HSC transplantation.</p><p><strong>Conclusions: </strong>The availability of this first cell therapy for relapsed or refractory mantle cell lymphoma provides an important option for patients. At present, treatment options for these patients, whose disease progresses after initial therapies, are almost nil. Thus, there is a felt need for new treatment options. The high response rates observed in the registrational study and confirmed by real-life data support the potential of KTE-X19 as an effective therapy for patients with relapsed or refractory mantle cell lymphoma, with a manageable safety profile.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 3","pages":"e50-e57"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The only effective treatments for long Covid are cognitive behavioral therapy and integrated physical and mental health rehabilitation.]","authors":"Alice Serafini, Allen F Shaughnessy","doi":"10.1701/4460.44563","DOIUrl":"https://doi.org/10.1701/4460.44563","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 3","pages":"195-196"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diario senegalese.","authors":"Marcello Semprini","doi":"10.1701/4460.44564","DOIUrl":"https://doi.org/10.1701/4460.44564","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 3","pages":"197-198"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}