Recenti progressi in medicina最新文献

[To achieve significant weight loss, at least 150 minutes per week of moderate exercise are needed.] [要达到显著的减肥效果，每周至少需要150分钟的适度运动。]

Recenti progressi in medicina Pub Date : 2025-03-01 DOI: 10.1701/4460.44562

Mario Luciano, David Slawson, Alice Serafini

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[Primary prevention of stroke: the updated guidelines from the American Heart Association and the American College of Cardiology.] [中风的初级预防：美国心脏协会和美国心脏病学会的最新指南]

Recenti progressi in medicina Pub Date : 2025-03-01 DOI: 10.1701/4460.44560

Viviana Forte, Henry Barry

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Dalla letteratura
2025 marzo. 2025年3月。

Recenti progressi in medicina Pub Date : 2025-03-01 DOI: 10.1701/4460.44550

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Numeri in questo numero
2025 marzo. 这个数字是2025年3月。

Recenti progressi in medicina Pub Date : 2025-03-01 DOI: 10.1701/4460.44549

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[Evaluating the accuracy of large language models in answering mammography screening questions in Italian and English: a study based on the Eusobi guidelines.] [评估大型语言模型在回答意大利语和英语乳房x光检查问题中的准确性：一项基于尤索比指南的研究。]

Recenti progressi in medicina Pub Date : 2025-03-01 DOI: 10.1701/4460.44556

Manuel Signorini, Silvia Fontani, Paola Minichetti, Silvia Teggi, Alessandra Barusco, Massimo Favat

{"title":"[Evaluating the accuracy of large language models in answering mammography screening questions in Italian and English: a study based on the Eusobi guidelines.]","authors":"Manuel Signorini, Silvia Fontani, Paola Minichetti, Silvia Teggi, Alessandra Barusco, Massimo Favat","doi":"10.1701/4460.44556","DOIUrl":"10.1701/4460.44556","url":null,"abstract":"Introduction: Artificial intelligence (AI) is transforming various aspects of everyday life, including healthcare, through large language models (LLMs) like ChatGPT, Gemini, and Copilot. These systems are increasingly used to disseminate medical information, allowing patients to access simplified explanations. This study aims to compare responses to breast imaging-related questions formulated in Italian and English, based on Eusobi guidelines, evaluating the LLMs' ability to provide accurate and complete answers on mammography screening concepts.Materials and methods: Nine questions related to breast cancer screening were developed by five breast radiologists based on Eusobi recommendations. These questions were submitted to ChatGPT, Gemini, and Copilot in both Italian and English. Responses were evaluated by two expert breast radiologists using a Likert scale (1 to 5), with statistical analysis performed to compare the accuracy, average length of responses, use of radiological sources and the agreement among readers.Results: The average scores for responses were similar in both languages, ranging from 3.6 to 4 out of 5. Questions on general mammography concepts received more accurate answers, while more specific questions based on the latest guidelines showed incomplete responses, especially about the definition of dense breast. The sources used, particularly in Italian, were often non-specialized in radiology, highlighting a limitation of LLMs in providing detailed and up-to-date medical answers.Conclusions: The study shows that LLMs are useful tools for medical communication, but they have limitations in delivering accurate answers on highly specialized medical topics. To improve the quality of information, collaboration between AI experts and healthcare professionals is necessary, especially in breast cancer prevention and screening.","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 3","pages":"162-167"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Strategies in using artificial intelligence to combat antimicrobial resistance. 利用人工智能对抗抗菌素耐药性的策略。

Recenti progressi in medicina Pub Date : 2025-03-01 DOI: 10.1701/4460.44557

Andrea Zovi, Giacomo Polito, Andrea Caprodossi, Michela Sabbatucci, Rosario Sorrentino, Antonio Vitiello

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["Kasomay" can help the children of Casamance.] [“卡索迈”可以帮助卡萨芒斯的孩子们。]

Recenti progressi in medicina Pub Date : 2025-03-01 DOI: 10.1701/4460.44552

Marcello Semprini

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[The only effective treatments for long Covid are cognitive behavioral therapy and integrated physical and mental health rehabilitation.] [长期Covid唯一有效的治疗方法是认知行为疗法和综合身心健康康复。]

Recenti progressi in medicina Pub Date : 2025-03-01 DOI: 10.1701/4460.44563

Alice Serafini, Allen F Shaughnessy

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Linfoma mantellare. mantellare淋巴瘤。

Recenti progressi in medicina Pub Date : 2025-03-01 DOI: 10.1701/4460.44567

Alessandro Broccoli, Pier Luigi Zinzani

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[CAR-T cell therapy in a patient with relapsed/refractory mantle cell lymphoma.] CAR-T细胞疗法治疗复发/难治性套细胞淋巴瘤

Recenti progressi in medicina Pub Date : 2025-03-01 DOI: 10.1701/4460.44570

Virginia Naso, Filippo Canale, Giorgia Policastro, Gaetana Porto, Maria Pellicano, Massimo Martino

{"title":"[CAR-T cell therapy in a patient with relapsed/refractory mantle cell lymphoma.]","authors":"Virginia Naso, Filippo Canale, Giorgia Policastro, Gaetana Porto, Maria Pellicano, Massimo Martino","doi":"10.1701/4460.44570","DOIUrl":"10.1701/4460.44570","url":null,"abstract":"Introduction: Mantle cell lymphoma (MCL) is one of the rarest forms of non-Hodgkin's lymphoma that mainly affects adults around 65 years of age or older, and is diagnosed when the disease has already reached a fairly advanced stage. Partly for this reason, but mainly because of the very characteristics of this rare form of lymphoma, the prognosis is often poor. In most cases, the disease recurs after a period of remission achieved with I-line. In the past decade, BTK inhibitors have become a mainstay of therapy for patients with relapsed/refractory mantle cell lymphoma. Although BTK inhibitors have improved the prognosis of relapsed/refractory mantle cell lymphoma, treatment options for patients who experience progression during or after BTK inhibitors remain limited. In this context, the development of anti-CD19 CAR T-cell therapy represents an important advance in the treatment of patients with chemorefractory MCL.Clinical case: We present the case of a 65-year-old man with diagnosis Mantle cell lymphoma MIPI intermediate risk, positive history only for hypertension, in disease progression during II-line therapy with Ibrutinib undertaken for relapse after of I-line polychemotherapy and consolidation with autologous HSC transplantation.Conclusions: The availability of this first cell therapy for relapsed or refractory mantle cell lymphoma provides an important option for patients. At present, treatment options for these patients, whose disease progresses after initial therapies, are almost nil. Thus, there is a felt need for new treatment options. The high response rates observed in the registrational study and confirmed by real-life data support the potential of KTE-X19 as an effective therapy for patients with relapsed or refractory mantle cell lymphoma, with a manageable safety profile.","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 3","pages":"e50-e57"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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