Viviana Forte, Allen F. Shaughnessy, Peter K. Kurotschka
{"title":"[Optimal pharmacological strategies for preventing migraine in children and adolescents.]","authors":"Viviana Forte, Allen F. Shaughnessy, Peter K. Kurotschka","doi":"10.1701/4450.44446","DOIUrl":"10.1701/4450.44446","url":null,"abstract":"<p><p></p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 2","pages":"124-125"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"“Ultime notizie dal cervello”.","authors":"","doi":"10.1701/4450.44448","DOIUrl":"https://doi.org/10.1701/4450.44448","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 2","pages":"127"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Linfoma diffuso a grandi cellule in seconda linea.","authors":"Alessandro Broccoli, Pier Luigi Zinzani","doi":"10.1701/4450.44449","DOIUrl":"https://doi.org/10.1701/4450.44449","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 2","pages":"e21-e23"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Experience of therapy with axi-cel CAR-T in an elderly patient suffering from double expressor DLBCL in an advanced stage and refractory to first-line chemoimmunotherapy.]","authors":"Maria Goldaniga","doi":"10.1701/4450.44451","DOIUrl":"https://doi.org/10.1701/4450.44451","url":null,"abstract":"<p><p>We hereby describe a case of successful therapy with axicabtagene ciloleucel (axi-cel) chimeric antigen receptor T-cells (CAR-T) in an elderly patient suffering from DLBCL refractory to first-line chemoimmunotherapy, with particular reference to the setting of the diagnostic/therapeutic path and collaboration between the Referral center and the CAR-T center.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 2","pages":"e28-e32"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Sharing research data.]","authors":"Annarita Barbaro","doi":"10.1701/4450.44438","DOIUrl":"https://doi.org/10.1701/4450.44438","url":null,"abstract":"<p><p>Data sharing is essential for scientific advancement, as exemplified by the Covid-19 pandemic. This crisis underscored the critical challenges of managing and sharing research data, which are not yet fully ingrained in scientific culture. To generate data that can be shared and reused, researchers should adhere to specific practices and ensure their data is FAIR (Findable, Accessible, Interoperable, Reusable). Major research funding agencies like Horizon Europe and the National Institutes of Health (NIH) now mandate the submission of Data Management Plans outlining how all project-related data will be managed and shared. The final section of this article delves into editorial policies regarding data sharing, the obstacles to sharing, and the emerging technologies and specialized roles needed to support efficient data management.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 2","pages":"77-82"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Making open access: history, developments and new challenges.]","authors":"Monica Zedda","doi":"10.1701/4450.44440","DOIUrl":"https://doi.org/10.1701/4450.44440","url":null,"abstract":"<p><p>The article traces the history and evolution of the Open Access (OA) Movement, officially lunched in 2001 with the Budapest Conference and solidified in 2003 with the Berlin Declaration. The OA Movement advocates for free and unrestricted access to publicly funded research results, asserting that scientific knowledge should be accessible to everyone without legal, economic, or technological barriers. The two main pathways for OA are outlined: self-archiving (green road) and publishing in entirely OA journals (gold road). The work also explores the concept of transformative journals and transformative agreements, designed to facilitate the transition of scientific journals to OA, even if with controversial and problematic outcomes. Additionally, the challenges and distortions of the publishing industry are analyzed, particularly the rising costs of Article Processing Charges (APCs) and the new OA strategies. The importance of alternative publishing models, such as diamond journals and OA platforms, is highlighted to promote more equitable and sustainable scientific communication. The role of major research funding bodies, including the European Commission and cOAlition S, is examined regarding policies and mandates for OA, emphasizing the need for a common commitment to overcome current legal and economic barriers. The article concludes that despite the progress made, many challenges remain unresolved. It calls for greater involvement of all stakeholders to implement concrete measures for awareness and support of OA. Only through collaboration at the political and institutional levels will it be possible to reshape the future of scientific publishing, break the oligopoly of major commercial publishers, and enable more democratic access to scientific knowledge.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 2","pages":"89-99"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Recognizing predatory journals.]","authors":"Manuela Moncada","doi":"10.1701/4450.44439","DOIUrl":"https://doi.org/10.1701/4450.44439","url":null,"abstract":"<p><p>Predatory journals cannot be considered trustworthy because of their lack of transparency and scientific rigor, for example within the peer review process. This phenomenon began to spread with the advent of open access journals and takes advantage of its economic model. Since a unanimous definition of predatory journal is lacking, it is difficult for a potential author of scientific articles to distinguish predatory journals from those respectful of the internationally shared best publication practices. To do so, it is useful to know the criteria by which scholarly journals are evaluated and considered, for instance for their indexing in bibliographic and bibliometric databases. These criteria relate primarily to the content of the journal, the internal organization of the journal and its business model, and the policies adopted to ensure research integrity, and are largely or entirely absent in predatory journals: the analysis of these aspects on journal websites can be crucial in order to choose the publishing venue for the publication of one's work.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 2","pages":"83-88"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Preprints and open archives and social networks. To each his own.]","authors":"Valeria Scotti","doi":"10.1701/4450.44441","DOIUrl":"https://doi.org/10.1701/4450.44441","url":null,"abstract":"<p><p>The article explores the topic of preprints and their growing use within the scientific community. Preprints are complete scientific manuscripts that authors upload to public repositories before undergoing peer review. This process allows for the near-immediate dissemination of research findings, enabling authors to receive early feedback from the scientific community. Preprints represent one of the key practices of Open Science, which aims to make research more accessible and transparent. The benefits of publishing preprints are numerous: researchers can quickly share their results, receive constructive criticism in a short time, and increase the visibility of their work, particularly for early-career scholars. The work further outlines the various preprint servers available and explains the difference between institutional repositories and academic social networks. Institutional repositories, managed by universities or public entities, are secure and ensure the long-term preservation of scientific data. In contrast, academic social networks, such as ResearchGate, are commercial platforms that may pose risks related to copyright violations. Finally, the document addresses the debate over the effectiveness of the traditional peer review system, which is often criticized for its slowness and lack of transparency. Preprints offer a complementary path to traditional publishing, allowing for faster and more open dissemination of scientific discoveries. However, they should be used cautiously, particularly in fields where peer review is essential to ensure the reliability of results.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 2","pages":"100-107"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonio Fabozzi, Paolo Onorati, Angelo Petroianni, Alessia Steffanina, Pia Baiocchi, Paolo Palange
{"title":"Pathophysiological and radiological patterns of pulmonary embolism in cancer vs Covid-19 patients.","authors":"Antonio Fabozzi, Paolo Onorati, Angelo Petroianni, Alessia Steffanina, Pia Baiocchi, Paolo Palange","doi":"10.1701/4450.44442","DOIUrl":"https://doi.org/10.1701/4450.44442","url":null,"abstract":"<p><strong>Purpose: </strong>Pulmonary embolism (PE) can compromise gases exchanges of patients admitted to respiratory wards. The objectives of this observational study were to identify radiological and arterial blood gases (ABG) differences in PEs documented by computed tomography pulmonary angiogram (CTPA) in Covid-19 pneumonia (C-19) vs cancer patients (CP).</p><p><strong>Methods: </strong>Fifty-one patients diagnosed with PE were evaluated, 18 CP and 33 C-19. Clinical, ABG and radiological parameters were evaluated. Jamovi software was used for statistics.</p><p><strong>Results: </strong>Wells score and D-dimer were both significantly higher in CP compared to C-19 cohort. DVT prevalence was significantly higher in CP patients. Alveolar-arterial O2 gradient (ΔA-aO2) was significantly higher in C-19 compared to CP cohort. PE associated to Covid-19 pneumonia was often bilateral and required a higher need of respiratory supports as High flow nasal cannula (HFNC), Continuous positive airway pressure (CPAP) and Non-invasive ventilation (NIV). In both cohorts, standard PaO2 and standard P/F were significantly lower than PaO2 and P/F. Multivariable linear regression analysis showed that in C-19 cohort PESI score and A-aO2 were independently and positively associated with PE severity.</p><p><strong>Discussion: </strong>These findings show that Wells score and D-dimer may underestimate PE's risk in C-19 patients. P/F may underestimate the severity of respiratory failure compared to standard P/F. A-aO2 may be a useful tool for prediction of PE severity.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 2","pages":"108-117"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Evidence shows superiority of triptans compared to both conventional and novel treatments in the management of acute migraine.]","authors":"Peter K Kurotschka, David Slawson, Alice Serafini","doi":"10.1701/4416.44120","DOIUrl":"https://doi.org/10.1701/4416.44120","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 1","pages":"53-54"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143010391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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