Recenti progressi in medicina最新文献_第7页

Prevalence of Covid-19 infection among healthcare workers in Central Hospitals of Covid-19 vs non-Covid-19 hospitals in Khuzestan Province, Iran. 伊朗胡齐斯坦省中心医院 Covid-19 与非 Covid-19 医院医护人员的 Covid-19 感染率。

Recenti progressi in medicina Pub Date : 2024-07-01 DOI: 10.1701/4314.42989

Khojasteh Hoseinynejad, Aram Asareh Zadegan Dezfuli, Mehran Varnasseri, Fatemeh Amini, Negar Varnasseri, Lida Mombeini, Soheila Moosaie, Fahimeh Abbasi Asl

{"title":"Prevalence of Covid-19 infection among healthcare workers in Central Hospitals of Covid-19 vs non-Covid-19 hospitals in Khuzestan Province, Iran.","authors":"Khojasteh Hoseinynejad, Aram Asareh Zadegan Dezfuli, Mehran Varnasseri, Fatemeh Amini, Negar Varnasseri, Lida Mombeini, Soheila Moosaie, Fahimeh Abbasi Asl","doi":"10.1701/4314.42989","DOIUrl":"10.1701/4314.42989","url":null,"abstract":"Background: Healthcare workers (HCWs) are at high risk of contracting Covid-19 due to their frontline roles and close interactions with infected patients. Understanding the prevalence of Covid-19 infection among HCWs and the factors contributing to it is crucial for informing mitigation strategies. However, the available data on Covid-19 infection rates among Iranian HCWs is limited.Objective: The primary objective of this study was to compare the prevalence of Covid-19 infection among HCWs working in hospitals dedicated to Covid-19 care versus HCWs in other non-Covid-19 hospitals in Khuzestan province, Iran. Additionally, the study aimed to identify potential risk factors associated with Covid-19 transmission and symptom severity in this population.Methods: This cohort study recruited 3,012 HCWs from 35 hospitals in Khuzestan province. Covid-19 diagnosis was made using RT-PCR testing, chest CT scans, and clinical examination.Results: Overall, 96% (n=2,918) of the 3,012 HCWs were infected with Covid-19. The prevalence was significantly higher among HCWs from Covid-19 hospitals (59.83%, n=1,746) compared to those from non-Covid-19 hospitals (5.75%, n=168). The capital city of Ahvaz had the highest proportion of Covid-19 cases at 28%.Conclusions: HCWs, especially those working in hospitals dedicated to Covid-19 care, face a substantial risk of contracting the virus. The high infection rates observed may be attributed to factors like weakened immune systems, non-compliance with precautions, and delayed diagnosis. These findings underscore the critical need to strengthen infection control measures, improve access to personal protective equipment, and enhance surveillance of Covid-19 among frontline HCWs in Iran.","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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[Update of the Pdta Net Observatory of the ReS Foundation with all regional Care Pathways approved until 2023.] [更新 ReS 基金会的 Pdta 网络观察站，所有地区护理路径均已批准，直至 2023 年]。

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42525

Irene Dell'Anno, Silvia Calabria, Nello Martini, Carlo Piccinni

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In questo numero
2024 Giugno. 本期内容2024年6月

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42521

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Recensioni.
"Sul pubblicare in medicina"
di Stefano Cagliano
"Franco Basaglia. Società, movimenti, istituzione, follia,corpo"
di Domenico Ribatti. 评论：斯特凡诺-卡利亚诺（Stefano Cagliano）的 "关于医学出版"，多梅尼科-里巴蒂（Domenico Ribatti）的 "佛朗哥-巴萨利亚。社会、运动、机构、疯狂、身体"，作者 Domenico Ribatti。

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42532

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[Efficacy of sacituzumab govitecan in a patient with TNBC with early relapse after neoadjuvant chemotherapy.] [新辅助化疗后早期复发的 TNBC 患者使用沙西妥珠单抗戈维替康的疗效]。

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42536

Francesca Carlino, Salvatore Feliciano

{"title":"[Efficacy of sacituzumab govitecan in a patient with TNBC with early relapse after neoadjuvant chemotherapy.]","authors":"Francesca Carlino, Salvatore Feliciano","doi":"10.1701/4274.42536","DOIUrl":"10.1701/4274.42536","url":null,"abstract":"Triple-negative breast cancers patients who relapse within 12 months from the end of neoaadjuvant chemotherapy represent a subgroup with a particularly poor prognosis, due to resistance to common chemotherapy treatments. Therefore, innovative therapeutic strategies are necessary for these patients. The therapeutic arsenal for triple-negative breast cancer has been enriched in recent years with new drugs, including antibody-drug conjugates. Sacituzumab govitecan, the first antibody directed against Trop-2, has been shown to improve survival in triple-negative metastatic breast cancer (the most aggressive subtype of breast cancer) in women who have received at least two prior chemotherapy treatments in the metastatic setting. This drug has demonstrated its effectiveness even in patients with early relapse after neoadjuvant treatment. In this clinical case we describe the story of a young patient with triple-negative breast cancer, with lymphnodal recurrence, who relapses within the first 12 months after the end of neoadjuvant chemotherapy. Sacituzumab govitecan resulted in a rapid and impressive clinical and instrumental response, associated with an improvement in quality of life and excellent functional status during therapy.","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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[Long-term response to second-line treatment with sacituzumab govitecan in a patient affected by brain disease and early relpased TNBC.] [一名脑部疾病和早期复发的TNBC患者对萨库珠单抗-戈维替康二线治疗的长期反应]

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42537

Vincenzo Di Lauro

{"title":"[Long-term response to second-line treatment with sacituzumab govitecan in a patient affected by brain disease and early relpased TNBC.]","authors":"Vincenzo Di Lauro","doi":"10.1701/4274.42537","DOIUrl":"10.1701/4274.42537","url":null,"abstract":"The higher frequency of metastasization and poor prognosis of triple-negative breast cancer require suitable expertise in order to set up an appropriate and effective treatment plan for these patients. Our case describes the clinical history of a 63-year-old BRCA1/2 wild-type woman with excellent ECOG performance status and advanced PD-L1 negative breast cancer with brain, nodal and hepatic metastases. When occurred the brain progression within one year from neoadjuvant chemotherapy for a locally advanced tumor, the patient was treated with brain stereotaxis and a systemic platinum-based therapy that was not completed due to poor tolerance. Later instrumental examinations confirmed a new systemic and visceral progression, for which the patient underwent new therapy with sacituzumab govitecan (SG). During this treatment, we observed a reduction of the target liver and nodal lesions. The onset after several months of two very small cortico-subcortical metastases, on which stereotactic radiotherapy was performed, did not lead us to discontinuate the treatment, that was ongoing for another six months, with an excellent control both of brain and systemic disease without any symptoms, until a new disease progression at other sites requiring a therapeutic change. The use of antibody-drug conjugates allowed a significant prolongation of time to progression and overall survival in our clinical scenario characterized by poor prognosis due to early recurrence and brain involvement.","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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[The right to health goes through the right to a home.] [健康权与住房权相辅相成]。

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42524

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[The stem cell and its context. Between the will to power and the will to relationship.] [干细胞及其背景。在权力意志与关系意志之间]

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42528

Domenico Ribatti

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[New educational approaches to the patient. A scoping review of systematic reviews.] [新的患者教育方法。系统综述的范围界定]。

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42527

Andrea Poliani, Giulia Villa, Silvia Gnecchi, Riccardo Bernardi, Giorgia Carta, Debora Rosa, Ilaria Marcomini, Duilio F Manara

{"title":"[New educational approaches to the patient. A scoping review of systematic reviews.]","authors":"Andrea Poliani, Giulia Villa, Silvia Gnecchi, Riccardo Bernardi, Giorgia Carta, Debora Rosa, Ilaria Marcomini, Duilio F Manara","doi":"10.1701/4274.42527","DOIUrl":"10.1701/4274.42527","url":null,"abstract":"Introduction: New educational approaches are emerging to assist healthcare professionals in better personalizing patient's educational pathways. Specifically, \"gamification\" - the incorporation of game elements into non-game contexts - appears to be a novel and affordable approach. This scoping review aims to explore and map the literature that evaluates the efficacy of gamification in healthcare contexts.Methods: A scoping review of reviews was conducted in MEDLINE, CINAHL, and PsycINFO using the JBI Manual for Evidence Synthesis guidelines and the PRISMA ScR checklist.Results: A total of four systematic reviews and four meta-analyses were included. It appears that gamification, when used in conjunction with other conventional educational tools, improves physical activity, facilitates better self-management of type 2 diabetes, improves cognitive functions, and improves the quality of life, particularly among specific groups like the elderly.Discussions: Gamification is an innovative educational approach that could be useful in patient's educational pathways. However, it seems that gamification is effective only in particular subgroups, and therefore the generalization of the results should also be assessed with caution due to the high risk of bias in the included studies and the small sample sizes considered.Conclusion: More randomized controlled trials and meta-analysis studies should be conducted to better understand the role and efficacy of gamification in patient education.","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Un mese nei tweet
per conoscere, per riflettere, per costruire reti. 在推特上学习、反思和建立网络的一个月。

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42523

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