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Recenti progressi in medicina最新文献

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Mappatura di organizzazione e attività di ricerca sanitaria e biomedica delle Aziende sanitarie piemontesi. 绘制皮埃蒙特卫生机构的卫生和生物医学研究组织与活动图。
Recenti progressi in medicina Pub Date : 2024-11-01 DOI: 10.1701/4365.43592
Marta Betti, Serena Penpa, Alessia Melito, Franco Ripa, Adriano Leli, Antonio Maconi
{"title":"Mappatura di organizzazione e attività di ricerca sanitaria e biomedica delle Aziende sanitarie piemontesi.","authors":"Marta Betti, Serena Penpa, Alessia Melito, Franco Ripa, Adriano Leli, Antonio Maconi","doi":"10.1701/4365.43592","DOIUrl":"https://doi.org/10.1701/4365.43592","url":null,"abstract":"<p><p>In the Piedmont Region, the first mapping of the organization and research activity of the 18 Health Authorities was conducted in 2022 through the Research and Innovation Department (DAIRI), repeated in 2023. The data showed an increase in scientific production and research funding and a decrease in clinical research, although the most represented infrastructure is for the activation of clinical trials. The importance of creating a regional research system is highlighted.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"115 11","pages":"538-540"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sacituzumab govitecan nel trattamento delle pazienti pluritrattate affette da tumore della mammella triplo negativo metastatico. 萨妥珠单抗戈维替康用于治疗多次治疗的转移性三阴性乳腺癌患者。
Recenti progressi in medicina Pub Date : 2024-11-01 DOI: 10.1701/4365.43614
Marta Perachino, Matteo Lambertini
{"title":"Sacituzumab govitecan nel trattamento delle pazienti pluritrattate affette da tumore della mammella triplo negativo metastatico.","authors":"Marta Perachino, Matteo Lambertini","doi":"10.1701/4365.43614","DOIUrl":"https://doi.org/10.1701/4365.43614","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"115 11","pages":"99e-101e"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Depression and effectiveness of psychedelics: high-dose psilocybin has shown benefits in improving symptoms.] [抑郁症和迷幻药的功效：大剂量迷幻药对改善症状有好处]。
Recenti progressi in medicina Pub Date : 2024-11-01 DOI: 10.1701/4365.43590
Viviana Forte, Allen F Shaughnessy, Peter K Kurotschka
{"title":"[Depression and effectiveness of psychedelics: high-dose psilocybin has shown benefits in improving symptoms.]","authors":"Viviana Forte, Allen F Shaughnessy, Peter K Kurotschka","doi":"10.1701/4365.43590","DOIUrl":"https://doi.org/10.1701/4365.43590","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"115 11","pages":"525-526"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effetti sulla mortalità per causa delle emissioni dei principali impianti industriali nel “Bacino del fiume Sacco”: uno studio di coorte amministrativa. Bacino del fiume Sacco "地区主要工业厂房排放物对全因死亡率的影响：一项行政队列研究。
Recenti progressi in medicina Pub Date : 2024-11-01 DOI: 10.1701/4365.43594
Emanuela Carloni, Chiara Badaloni, Matteo Renzi, Alessandro Trentalange, Letizia Leccese, Daniela Porta, Paola Michelozzi
{"title":"Effetti sulla mortalità per causa delle emissioni dei principali impianti industriali nel “Bacino del fiume Sacco”: uno studio di coorte amministrativa.","authors":"Emanuela Carloni, Chiara Badaloni, Matteo Renzi, Alessandro Trentalange, Letizia Leccese, Daniela Porta, Paola Michelozzi","doi":"10.1701/4365.43594","DOIUrl":"10.1701/4365.43594","url":null,"abstract":"<p><p>The River Sacco Basin (Rsb) is a site of National interest, characterized by several environmental pressures such as industrial facilities. This study investigates the association between long-term exposure to industrial-PM10 and -NOx and cause-specific mortality (non-accidental, cardiovascular, respiratory, and cancer) in the Rsb in the 2006-2018 period. We enrolled 301,681 residents near 14 major industrial plants (grouped into 5 30-km2 spatial domains). Residential exposure to annual PM10 and NOx was considered as categorical exposure (high (>80th percentile), medium (50th-80th), and low (<50th)). We applied adjusted domain specific Cox regression models (covariates: age, sex, and deprivation index) and performed a relative meta-analysis. We obtain a pooled 34% increase in respiratory mortality for high PM10 levels. Elevated risks were also observed for non-accidental and cancer mortality, highlighting the need for continuous monitoring and preventive interventions.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"115 11","pages":"543-544"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Sacituzumab govitecan in the second line treatment in a patient with triple-negative breast cancer with extensive locoregional recurrence.] [萨妥珠单抗-戈维替康用于广泛局部复发的三阴性乳腺癌患者的二线治疗]。
Recenti progressi in medicina Pub Date : 2024-11-01 DOI: 10.1701/4365.43611
Maria Vittoria Bonomo, Valeria Flaminio, Ilaria Portarena
{"title":"[Sacituzumab govitecan in the second line treatment in a patient with triple-negative breast cancer with extensive locoregional recurrence.]","authors":"Maria Vittoria Bonomo, Valeria Flaminio, Ilaria Portarena","doi":"10.1701/4365.43611","DOIUrl":"10.1701/4365.43611","url":null,"abstract":"<p><p>Triple-negative breast cancer (TNBC) is a heterogeneous disease with an aggressive clinical course and worse outcomes than other breast cancer subtypes. Metastatic triple-negative breast cancer (mTNBC) is characterized by an aggressive clinical course and unfavorable outcomes, despite the pharmacological treatments used. The present clinical case describes a 35-year-old woman affected by TNBC characterized by rapid and subsequent local, cutaneous and lymph node progression of the disease. It was initially necessary to perform surgical treatment without the patient having completed neoadjuvant chemotherapy. 4 months after the end of adjuvant chemotherapy the patient underwent a second surgery. Then, she started the first line and, after 4 cycles, the second line with sacituzumab govitecan (SG) obtaining at the first instrumental re-evaluation a partial skin and lymph node response with a clear reduction in painful symptoms previously reported at the level of the right chest wall and axillary cavity. She continued treatment for a total of 9 cycles. The case confirms the clinical benefit and effectiveness of treatment with SG, in particular it underlines the good control of the disease characterized by a rapid and progressive course with exclusively locoregional extension and good control of symptoms with an improvement in quality of life.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"115 11","pages":"86e-89e"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Long-term efficacy and safety with sacituzumab govitecan in a patient with triple-negative breast cancer, multi-treated and high body mass index.] [萨希妥珠单抗戈维替康对一名三阴性乳腺癌患者的长期疗效和安全性，该患者接受过多种治疗且体重指数较高。］
Recenti progressi in medicina Pub Date : 2024-11-01 DOI: 10.1701/4365.43617
Maria Morritti
{"title":"[Long-term efficacy and safety with sacituzumab govitecan in a patient with triple-negative breast cancer, multi-treated and high body mass index.]","authors":"Maria Morritti","doi":"10.1701/4365.43617","DOIUrl":"10.1701/4365.43617","url":null,"abstract":"<p><p>The metastatic triple negative breast cancer (mTNBC) represents a particularly aggressive form of breast cancer that frequently affects young women under the age of 50. Obesity at the time of breast cancer diagnosis is associated with a worse prognosis. Compared to the recent past, increasing life expectancy and quality of life for patients with mTNBC is now a possible challenge, thanks to a new drug, sacituzumab govitecan (SG), an anti-Trop-2 antibody drug conjugate approved as monotherapy for the treatment of these patients. The presented clinical case documents the efficacy and safety of long-term treatment with SG in an obese young woman with mTNBC who has already undergone multiple treatments. The patient is still responding after 20 months of treatment with good quality of life and social interactions.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"115 11","pages":"110e-115e"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[In adult premenopausal women with frequent urinary tract infections, oral or vaginal probiotics reduce the likelihood of recurrence.] [对于尿路感染频繁的绝经前成年妇女，口服或阴道益生菌可降低复发的可能性]。
Recenti progressi in medicina Pub Date : 2024-11-01 DOI: 10.1701/4365.43586
Peter K Kurotschka, Mark H Ebell, Alice Serafini
{"title":"[In adult premenopausal women with frequent urinary tract infections, oral or vaginal probiotics reduce the likelihood of recurrence.]","authors":"Peter K Kurotschka, Mark H Ebell, Alice Serafini","doi":"10.1701/4365.43586","DOIUrl":"https://doi.org/10.1701/4365.43586","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"115 11","pages":"517-518"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In questo numero
2024 Novembre. 本期，2024 年 11 月。
Recenti progressi in medicina Pub Date : 2024-11-01 DOI: 10.1701/4365.43580
{"title":"In questo numero<br>2024 Novembre.","authors":"","doi":"10.1701/4365.43580","DOIUrl":"https://doi.org/10.1701/4365.43580","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"115 11","pages":"495"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[An interactive tailored text messaging intervention can reduce electronic cigarette use (vaping) in adolescents aged 13-17.] [互动式定制短信干预可减少 13-17 岁青少年使用电子香烟（吸食电子烟）]。
Recenti progressi in medicina Pub Date : 2024-11-01 DOI: 10.1701/4365.43588
Peter K Kurotschka, David C Slawson, Viviana Forte
{"title":"[An interactive tailored text messaging intervention can reduce electronic cigarette use (vaping) in adolescents aged 13-17.]","authors":"Peter K Kurotschka, David C Slawson, Viviana Forte","doi":"10.1701/4365.43588","DOIUrl":"https://doi.org/10.1701/4365.43588","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"115 11","pages":"521-522"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Artificial intelligence integrated in a smartphone app is accurate in diagnosing melanoma in individuals with lighter skin color.] [集成在智能手机应用程序中的人工智能可准确诊断肤色较浅者的黑色素瘤]。
Recenti progressi in medicina Pub Date : 2024-11-01 DOI: 10.1701/4365.43587
Peter K Kurotschka, Mark H Ebell, Viviana Forte
{"title":"[Artificial intelligence integrated in a smartphone app is accurate in diagnosing melanoma in individuals with lighter skin color.]","authors":"Peter K Kurotschka, Mark H Ebell, Viviana Forte","doi":"10.1701/4365.43587","DOIUrl":"10.1701/4365.43587","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"115 11","pages":"519-520"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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