Recenti progressi in medicina最新文献_第8页

Sacituzumab govitecan come seconda linea nell’algoritmo terapeutico delle pazienti ricadute precocemente dal termine della terapia neoadiuvante. 将萨妥珠单抗戈维替康作为新辅助治疗结束后早期复发患者的二线治疗方案。

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42534

Marta Perachino, Matteo Lambertini

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Dalla letteratura
2024 Giugno. 来自文献 2024 年 6 月。

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42522

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[Patient with TNBC with early relapse within 12 months from adjuvant treatment.] [辅助治疗后 12 个月内早期复发的 TNBC 患者]。

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42535

Alessandra Beano

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Emergenza e piccoli miracoli al pronto soccorso. 急诊室里的急诊和小奇迹

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42530

Vittorio Fontana

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Paul Auster: «The story is not in the words: it’s in the struggle.». 保罗-奥斯特"故事不在文字里，而在奋斗中。

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42531

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[Supposed allergy to beta-lactam antibiotics: is it time for reflections and actions?] [假设对β-内酰胺类抗生素过敏：是时候进行反思并采取行动了吗？］

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42526

Federico Marchetti, Laura Badina, Irene Berti

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[Top 5 Research Studies of the month for Italian Primary Care Physicians: May 2024.] [意大利初级保健医生本月 5 大研究：2024 年 5 月]。

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42529

Peter K Kurotschka, Alice Serafini, Allen Shaughnessy, David Slawson, Mark H Ebell

{"title":"[Top 5 Research Studies of the month for Italian Primary Care Physicians: May 2024.]","authors":"Peter K Kurotschka, Alice Serafini, Allen Shaughnessy, David Slawson, Mark H Ebell","doi":"10.1701/4274.42529","DOIUrl":"https://doi.org/10.1701/4274.42529","url":null,"abstract":"This monthly article provides a collection of summaries of the most relevant studies identified as POEMs (patient-oriented evidence that matters) for Italian primary care physicians. 1) The 2023 updated American college of cardiology/American heart association guideline provide new recommendations for the diagnosis and treatment of atrial fibrillation. In a nutshell, screening is not recommended, and treatment decisions should be guided by risk assessment via CHA2DS2-VASC or a similar tool. For most patients, a direct oral anticoagulant (Doac) at a standard dose is recommended. 2) The use of gabapentin or pregabalin is associated with severe exacerbation of chronic obstructive pulmonary disease (Copd). Various government agencies warn about the use of those gabapentinoids in patients with respiratory risk factors. 3) In children 3 months to 5 years of age with an uncomplicated febrile urinary tract infection, 5 days of antibiotic treatment results in similar resolution of symptoms and 30-day recurrence rates as 10 days of treatment. 4) In adults with type 2 diabetes, bariatric surgery results in superior glycemic control and weight loss compared with medical plus lifestyle management. However, no significant differences occurred in major adverse cardiovascular events or all-cause mortality. Other (non-cardiovascular) adverse events occurred significantly more often in the surgery group, so it is uncertain whether the overall quality of life, morbidity or mortality are better or worse with surgery. 5) Prescribing a specific exercise program, whether aerobic or strength training, produces clinically meaningful and statistically significant benefits in patients with major depressive disorder. The advice can't be simply to \"exercise more\" but should be a specific exercise prescription, just like a medication prescription, specifying the frequency, intensity, time (duration), and type of exercise.","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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L’intelligenza artificiale amplifica la disinformazione? 人工智能会放大虚假信息吗？

Recenti progressi in medicina Pub Date : 2024-06-01 DOI: 10.1701/4274.42533

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[Top 4 Research Studies of the month for Italian Primary Care Physicians: April 2024.] [意大利初级保健医生本月的四大研究：2024 年 4 月]。

Recenti progressi in medicina Pub Date : 2024-05-01 DOI: 10.1701/4262.42404

Peter K Kurotschka, Alice Serafini, Allen F Shaughnessy, David Slawson, Mark H Ebell

{"title":"[Top 4 Research Studies of the month for Italian Primary Care Physicians: April 2024.]","authors":"Peter K Kurotschka, Alice Serafini, Allen F Shaughnessy, David Slawson, Mark H Ebell","doi":"10.1701/4262.42404","DOIUrl":"https://doi.org/10.1701/4262.42404","url":null,"abstract":"This monthly article provides a collection of summaries of the most relevant studies identified as POEMs (patient-oriented evidence that matters) for Italian primary care physicians. 1) In children and adults with acute conjunctivitis, antibiotic drops increase the likelihood that a patient will experience clinical recovery. Damage appears to be minimal for all agents other than fusidic acid (therefore, fusidic acid should be avoided). Since most patients improve without antibiotics, the benefit is modest, and there is a risk of antibiotic resistance, we would avoid them for patients with milder symptoms, especially immunocompetent adults. 2) A high quality randomized controlled trial was recently conducted on more than 4000 adult patients with recurrent episodes of subclinical atrial fibrillation. Trialists found that there was approximately 1 fewer ischemic stroke and 1 more major bleed for every 250 persons treated with apixaban instead of aspirin, but in people treated with apixaban major bleeding was also significantly more likely. This seems like a decision that requires an informed patient and shared decision-making. 3) In an intriguing but somewhat limited network meta-analysis, probiotics were equally or more effective than treatment with any antidepressant except escitalopram. Given the low advantage of standard treatments over placebo, probiotic treatment might be offered to patients who are reluctant to use antidepressants. 4) A recent meta-analysis showed that amyloid-targeting monoclonal antibodies do not provide any clinical meaningful benefits for patients with Alzheimer disease. Instead, they are associated with concerning risks of harm, most notably cerebral hemorrhage identified on imaging studies. The balance of risk versus benefit demonstrated thus far doesn't justify the use of these costly (over US$ 20,000 annually) drugs.","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Dalla letteratura. 来自文献。

Recenti progressi in medicina Pub Date : 2024-05-01 DOI: 10.1701/4262.42397

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