Recenti progressi in medicina最新文献

{"title":"Endonasal filters for the prevention and control of respiratory allergy and infections. A multi-stakeholder assessment.","authors":"Marta Rigoni, Valeria Cento, Carlo Federico Perno, Martina Barchitta, Antonella Agodi, Sergio Bonini, Fabiana Furci, Silvana D'Alessio, Simona Barbaglia, Sandra Frateiacci, Annarosa Racca, Giuseppe Fornasa, Francesco Broccolo, Guido Rasi, Giuseppe Recchia, Lucio Da Ros, Giandomenico Nollo","doi":"10.1701/4518.45174","DOIUrl":"10.1701/4518.45174","url":null,"abstract":"<p><p>Healthcare innovations aim to develop and provide technologies, services, and health policies to improve population health and well-being at a global level. Among innovative medical devices (MD), endonasal filters (EF) are designed to improve breathing and capture fine dust and allergens in the surrounding environment acting as a mechanical barrier to the passage of allergens, pathogenic microorganisms and dust. This paper aimed to: i) review the features of EF commercially available, regulatory classification, and their potential role in public health as useful innovative devices; ii) review their role in prevention and control of respiratory infections; iii) review their role in prevention and control of allergic respiratory diseases. A review of MD on the market was carried out through official Ministry of Health, commercial and pharmaceutical channels. Moreover, three separate literature reviews were done by the involved multidisciplinary team. The analysis of the European market, with particular attention to Italy, on available MD identified seven brands of EF. A search conducted at 16th April 2023 in Italian MD Database of the Ministry of Health revealed that three products were registered as MD and they were available on the Italian market. Literature review found 3 studies on nasal filter technical description, 4 studies on patients on infectious diseases and other applications, and 13 studies on patients on respiratory allergy. Studies on infectious diseases were one review, and one correspondence reporting a research proposal. Studies on respiratory allergy included 3 randomized controlled studies, 5 observational open-label non-randomized studies, 2 case series, 1 case report, 1 review, and 1 systematic review. Despite reasonable theoretical fundamentals to claim that EF might contribute to the reduction of infection viral load, current evidence supporting the use of such filters is still scarce, suggesting the need to further research and comprehensive assessments for developing ad hoc documents, guidelines and recommendations.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 6","pages":"357-370"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modern medical epistemology in the Divine Comedy: a few suggestions on evidence-based medicine.","authors":"Nicola Baldi","doi":"10.1701/4518.45172","DOIUrl":"10.1701/4518.45172","url":null,"abstract":"<p><p>Dante's knowledge of the various fields of medieval medicine, in terms of disease patterns and pathogenetic hypotheses, is well known. At that time, Dante acquired this knowledge by attending, directly or indirectly, the lessons of Taddeo Alderotti, one of the founders of the Medical School in Bologna. Regarding Dante's attitude towards medicine and science in general, in this paper has been considered the episode of Pier della Vigna, presented in the thirteenth canto of the Inferno. This concern how the origin of the cries and lamentations is established, which come from the weeds into which the suicides had turned. A parallel has also been drawn between Dante's approach and the methods used today in the diagnosis and treatment of diseases using Evidence-Based Medicine. Moreover, some hypotheses have also been ventured about the origin of this parallelism.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 6","pages":"341-347"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The current role of CAR-T cell treatment in lymphoma therapy: focus on diffuse large cell lymphoma and mantle cell lymphoma].","authors":"Alessandro Broccoli, Pier Luigi Zinzani","doi":"10.1701/4495.44947","DOIUrl":"10.1701/4495.44947","url":null,"abstract":"<p><p>The aim of this work is to provide the information needed to adequately apply chimeric antigen receptor T-cell (CAR-T) therapy in real clinical practice in outpatient, day hospital and ward settings, with a particular focus on patients with diffuse large cell lymphoma and mantle cell lymphoma, which currently represent the main area of use of anti-CD19 CAR-T treatment. The currently approved indications in both contexts are reviewed and the fundamental steps to follow in starting CAR-T cell therapy are described, as well as the data available in the literature regarding each previously presented indication.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 5","pages":"272-284"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large language models in answering mammography screening questions in Italian and English: Comment.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1701/4495.44956","DOIUrl":"10.1701/4495.44956","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 5","pages":"330"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Intensive blood pressure targets significantly reduce stroke and cardiovascular outcomes in patients with type 2 diabetes].","authors":"Viviana Forte, Allen F Shaughnessy","doi":"10.1701/4495.44953","DOIUrl":"10.1701/4495.44953","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 5","pages":"324-325"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recensione<br>“Corpo, umano”.","authors":"","doi":"10.1701/4495.44958","DOIUrl":"https://doi.org/10.1701/4495.44958","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 5","pages":"334"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Antiviral drugs for influenza shorten symptoms by 24 hours or less and don't reduce hospitalizations or deaths].","authors":"Alice Serafini, Mark H Ebell","doi":"10.1701/4495.44952","DOIUrl":"10.1701/4495.44952","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 5","pages":"322-323"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The challenges for global health].","authors":"Massimo Sartelli","doi":"10.1701/4495.44946","DOIUrl":"10.1701/4495.44946","url":null,"abstract":"<p><p>The world is facing an unprecedented moment of destabilization, where multiple, interconnected challenges threaten public health with the potential to exacerbate existing inequalities and jeopardize global health security. In an era of profound changes, health workers must understand the challenges facing global health to respond with cohesion and determination. Global collaboration represents a beacon of hope and success and can foster unified efforts to address complex challenges for a healthier and more equitable global future.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 5","pages":"269-271"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Uncomplicated urinary tract infections: the new antibiotic gepotidacin is at least as effective as nitrofurantoin].","authors":"Peter K Kurotschka, Henry Barry","doi":"10.1701/4495.44954","DOIUrl":"10.1701/4495.44954","url":null,"abstract":"","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 5","pages":"326-327"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gamification in medical sciences education: a scoping review.","authors":"Mohammad Rasool Khazaei, Mohammad Ali Hosseini, Ghobad Ramezani","doi":"10.1701/4495.44949","DOIUrl":"10.1701/4495.44949","url":null,"abstract":"<p><strong>Background & objective: </strong>Recently, the use of educational games in teach has received the attention of medical education experts. There is a belief that educational games can be used in line with the individual characteristics and diverse learning styles of students. Games in medical education are presented in different forms, including simulation, virtual environments, collaborative and social games, and virtual reality alternative games. A more detailed understanding of the impact of this new method requires more extensive studies. The current research was conducted with the aim to explain the elements affecting the implementation of gamification in medical science education with a scoping review approach.</p><p><strong>Methods: </strong>A scoping review was conducted in Irandoc, SID, and Magiran, Scopus, Science Direct, PubMed, Eric, MEDLINE, PsycINFO, Google Scholar and resources available in the library, theses, research plans between October 2012 and May 2024. Seventy-eight articles met the inclusion criteria. CASP checklists and AMSTAR was used to assess the quality of the articles.</p><p><strong>Results: </strong>Out of a total of 44,165 primary articles, 47 articles remained in the study for the final synthesis. The effective components in gamification included: educational design, virtual awards and points, scoreboards, learner characteristics, interaction with the learning environment, information context, game mechanics and reinforcements. The strategies used in the implementation of gamification included: use challenge, imagination, curiosity, visualization, game dynamics, role-playing and aesthetic. Effective variables of gamification including: increasing students' participation, increasing learning, increasing motivation, reducing anxiety, improving academic performance, reducing professors' workload, increasing satisfaction, active participation in discussion, attractiveness of education, social skills, role playing, self-efficacy, knowledge, skill. The elements of gamification are: goals, rules, feedback, challenge, valuable results, scoreboard and medals.</p><p><strong>Conclusions: </strong>Today, using the existing potential of gamification in medical education curriculum as an effective approach plays a significant role in improving the teaching-learning process of students in this field.</p>","PeriodicalId":20887,"journal":{"name":"Recenti progressi in medicina","volume":"116 5","pages":"291-301"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}