【CAR-T细胞治疗目前在淋巴瘤治疗中的作用：重点是弥漫性大细胞淋巴瘤和套细胞淋巴瘤。】

Q3 Medicine

Recenti progressi in medicina Pub Date : 2025-05-01 DOI:10.1701/4495.44947

Alessandro Broccoli, Pier Luigi Zinzani

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引用次数: 0

摘要

这项工作的目的是提供在门诊、日间医院和病房环境中充分应用嵌合抗原受体t细胞（CAR-T）治疗所需的信息，特别关注弥漫大细胞淋巴瘤和套细胞淋巴瘤患者，这是目前使用抗cd19 CAR-T治疗的主要领域。本文回顾了目前在这两种情况下批准的适应症，并描述了开始CAR-T细胞治疗的基本步骤，以及文献中关于每个先前提出的适应症的可用数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

[The current role of CAR-T cell treatment in lymphoma therapy: focus on diffuse large cell lymphoma and mantle cell lymphoma].

The aim of this work is to provide the information needed to adequately apply chimeric antigen receptor T-cell (CAR-T) therapy in real clinical practice in outpatient, day hospital and ward settings, with a particular focus on patients with diffuse large cell lymphoma and mantle cell lymphoma, which currently represent the main area of use of anti-CD19 CAR-T treatment. The currently approved indications in both contexts are reviewed and the fundamental steps to follow in starting CAR-T cell therapy are described, as well as the data available in the literature regarding each previously presented indication.

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来源期刊

Recenti progressi in medicina Medicine-Medicine (all)

CiteScore

0.90

自引率

0.00%

发文量

143

期刊介绍： Giunta ormai al sessantesimo anno, Recenti Progressi in Medicina continua a costituire un sicuro punto di riferimento ed uno strumento di lavoro fondamentale per l"ampliamento dell"orizzonte culturale del medico italiano. Recenti Progressi in Medicina è una rivista di medicina interna. Ciò significa il recupero di un"ottica globale e integrata, idonea ad evitare sia i particolarismi della informazione specialistica sia la frammentazione di quella generalista.