Psychiatria polskaPub Date : 2024-05-20DOI: 10.12740/PP/OnlineFirst/185461
Renata Modrzejewska, Anna Wasik, Paulina Cofór-Pinkowska, Agnieszka Pac, Marcin Siwek
{"title":"Changes in temperament, character and intensity of empathy in adolescents treated in a day care unit - pilot study.","authors":"Renata Modrzejewska, Anna Wasik, Paulina Cofór-Pinkowska, Agnieszka Pac, Marcin Siwek","doi":"10.12740/PP/OnlineFirst/185461","DOIUrl":"https://doi.org/10.12740/PP/OnlineFirst/185461","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this pilot study was to compare the level of empathy, temperament and character traits before and after 6 months of treatment in a group of patients staying in a psychiatric day care unit in groups with different (internalising vs. externalising) disorder types.</p><p><strong>Methods: </strong>The study was conducted in a group of 44 patients (33 girls and 11 boys), aged 15-20, treated between 2016 and 2021 in the Clinical Day Care Unit of the Department of Adult, Child and Adolescent Psychiatry of the University Hospital in Krakow. 40% of the adolescents had externalising disorders and 60% had internalising disorders. The Davis Empathy Scale and the Cohen Empathy Scale were used in the study, as well as the Cloninger' Temperament and Character Inventory (TCI).</p><p><strong>Results: </strong>Six months of treatment in a day care unit resulted in statistically significant changes in the \"Fantasy\" scale from the Davis Empathy Scale, in the \"Reward dependence\", \"Self-directedness\" and \"Self-transcendence\" subscales on the Temperament and Character Inventory in the group of adolescents with internalising disorders. In the group of adolescents with externalising disorders, there were changes at the level of statistical trend in the values of the \"Fantasy\" scale and the \"Harm Avoidance\" scale of the Temperament and Character Inventory.</p><p><strong>Conclusions: </strong>The obtained results are in line with the available data in terms of differences in temperament and character profiles between types of mental disorders and constellations of traits that are unfavourable for mental health, such as low self-directedness, harm avoidance and reward dependence.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"1-15"},"PeriodicalIF":0.9,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Psychiatria polskaPub Date : 2024-04-30DOI: 10.12740/PP/OnlineFirst/154033
Iga Plencler, Dawid Kruk, Artur Daren, Przemysław Stankiewicz, Agnieszka Nowak, Stanisław Radoń, Adrian Chrobak, Andrzej Cechnicki, Marcin Siwek
{"title":"The effects of mindfulness-based training in virtual reality on psychotic symptoms, mood and cognitive functioning - a pilot study.","authors":"Iga Plencler, Dawid Kruk, Artur Daren, Przemysław Stankiewicz, Agnieszka Nowak, Stanisław Radoń, Adrian Chrobak, Andrzej Cechnicki, Marcin Siwek","doi":"10.12740/PP/OnlineFirst/154033","DOIUrl":"10.12740/PP/OnlineFirst/154033","url":null,"abstract":"<p><strong>Objectives: </strong>Virtual reality (VR) is growing in popularity in treating various psychiatric disorders, including psychotic ones. However, no studies have been published on mindfulness interventions aided by virtual reality in psychotic patients to date.</p><p><strong>Methods: </strong>25 patients with schizophrenia or schizoaffective disorder were assessed at three time points with 4-week intervals using the six-item Positive and Negative Syndrome Scale (PANSS-6), Quick Inventory of Depressive Symptomatology (QIDS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), State-Trait Anxiety Inventory (STAI), Perceived Stress Scale (PSS-10), and the Addenbrooke's Cognitive Examination III (ACE-III). Additionally, the intensity of seven emotions was rated using the Visual Analog Scale (VAS) before and after each training session.</p><p><strong>Results: </strong>The subjects achieved a significant reduction in symptom severity after completing mindfulness training. This was reflected by the PANSS-6 total score, as well as by the subscales for negative and positive symptoms. A significant increase in cognitive functioning (ACE-III scores) was also found. No significant changes in these measures were observed when only the standard intervention was used.</p><p><strong>Conclusions: </strong>Our study indicates good feasibility of the developed mindfulness intervention in VR in schizophrenic patients. The results indicate potential benefits in terms of lessening of the symptoms and improvement in cognition.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"289-302"},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9158483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Psychiatria polskaPub Date : 2024-04-30DOI: 10.12740/PP/OnlineFirst/156320
Jan Chrobak, Patryk Rodek, Krzysztof Kucia
{"title":"Multiple-Monitored Electroconvulsive Therapy (MMECT) - does it really just belong in psychiatry's past? A case report.","authors":"Jan Chrobak, Patryk Rodek, Krzysztof Kucia","doi":"10.12740/PP/OnlineFirst/156320","DOIUrl":"10.12740/PP/OnlineFirst/156320","url":null,"abstract":"<p><p>Electroconvulsive therapy has been a method used in psychiatry since 1938 and despite its rather turbulent history, it is still the most effective method of treating severe mental disorders. Despite its high efficiency and good safety profile, patients with catatonia usually require a large number of treatments. It entails a long hospitalization time and the necessity to repeatedly induce general anesthesia. In 1966, Blachly proposed to induce more than one seizure during a single anesthesia. According to this method, the patient was to be constantly monitored (ECG, EEG) during a series of electroconvulsions, which consisted of two to even eight treatments. For simplicity, the method is called multiple-monitored ECT (MMECT). The work is based on the medical history of a patient diagnosed with catatonic schizophrenia. Due to the insufficient effect of single treatments, we decided to use the MMECT method, which was performed in series of three treatments, twice a week. Thanks to the therapy, catatonic symptoms remitted. Studies in various patient populations have shown that MMECT reduces hospitalization time, the duration of acute symptoms, and the patient's total exposure to anesthetics and muscle relaxants. As the above case shows, MMECT can potentially be considered as a safe treatment alternative in patients that require a large number of treatments, resistant to standard forms of therapy.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"343-349"},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9727881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sixty years of recurrence prevention in mood disorders.","authors":"Janusz Rybakowski","doi":"10.12740/PP/169407","DOIUrl":"10.12740/PP/169407","url":null,"abstract":"<p><p>This year, we observe sixty's anniversary of the article by a British psychiatrist, Geoffrey Hartigan, demonstrating, for the first time, the possibility of preventing of the recurrence of mood disorders by using lithium salts. Herein, a history of prevention of recurrences of mood disorders both worldwide and in Poland will be presented concerning both lithium and other mood-stabilizing drugs. The merit for verifying the prophylactic lithium effect in the 1960-1970s should be given to Danish researchers, Mogens Schou and Poul Baastrup. In Poland, the first paper on prophylactic lithium appeared already in 1971. In the 1970s, French researchers showed prophylactic activity of valproic acid amide, and Japanese researchers - carbamazepine. In the 1980th, studies on valproic acid amide were performed in the 2nd Psychiatric Clinic of the Institute of Psychiatry and Neurology led by Prof. Pużyński. Since the mid-1990s, 2nd generation of mood-stabilizing drugs has been introduced, including some atypical antipsychotics (clozapine, olanzapine, quetiapine, aripiprazole, risperidone) and anticonvulsant drug, lamotrigine, showing prophylactic activity in bipolar mood disorder. The studies on lithium resulted in the identification of factors connected with its prophylactic efficacy as well as the antisuicidal, antiviral, and neuroprotective effects of this drug. From a sixty-year perspective following Hartigan's article, it seems that his pioneering concept on the possibility of pharmacological influence on the course of mood disorders was fully confirmed. Current Polish recommendations on pharmacological prophylaxis of mood disorders were presented in the books \"Standardy leczenia niektórych zaburzeń psychicznych\" and \"Psychofarmakologia kliniczna\", both published in 2022.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 2","pages":"223-236"},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Psychiatria polskaPub Date : 2024-04-30DOI: 10.12740/PP/OnlineFirst/154985
Renata Modrzejewska, Anna Wasik, Paulina Cofór-Pinkowska, Agnieszka Pac, Marcin Siwek
{"title":"The intensity of empathy in adolescents treated in a day unit - preliminary reports.","authors":"Renata Modrzejewska, Anna Wasik, Paulina Cofór-Pinkowska, Agnieszka Pac, Marcin Siwek","doi":"10.12740/PP/OnlineFirst/154985","DOIUrl":"10.12740/PP/OnlineFirst/154985","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the pilot study was to compare the level of empathy among adolescents treated in a psychiatric day unit in groups with varied age, gender and type of disorder (conduct and emotional disorders and depressive-anxiety disorders).</p><p><strong>Methods: </strong>The study was carried out in a group of 117 adolescents (69 girls and 48 boys) aged 13-20, treated in the Clinical Day Unit of the Department of Adult, Child and Adolescent Psychiatry of the University Hospital in Kraków between 2016-2021. The Davis Empathy Scale and the Cohen Empathy Scale were used for the study.</p><p><strong>Results: </strong>Girls scored significantly higher compared to boys on the Cohen and Davis Empathy scales and on the Davis subscale: Personal Distress. Statistically significant interactions were observed for the factors of gender and age, as well as age and disorder type. Older boys had statistically significantly higher scores on the Davis Empathy Scale compared to younger boys, while the reverse pattern was observed for girls (non-significant). Older patients with conduct disorders had significantly lower Cohen's Empathy Scale scores compared to younger patients; the opposite pattern was observed in the group of patients with anxiety-depressive disorders (non-significant).</p><p><strong>Conclusions: </strong>Girls exhibit higher levels of affective and cognitive empathy than boys. The intensity of empathy increases with age in the group of boys, while for girls the obtained differences are not statistically significant. The intensity of empathy is significantly lower in the group of older adolescents (versus younger) with conduct and emotional disorders. Among depressive-anxiety disorders, the opposite pattern was noted (non-significant). The unique results obtained indicate a different trajectory of empathy development in the group of patients with conduct disorders and with depressive-anxiety disorders.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"329-342"},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9327602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ewa Kurczewska, Ewa Ferensztajn-Rochowiak, Janusz Rybakowski, Filip Rybakowski
{"title":"Sensory Processing Sensitivity as a trait of temperament - evolutionary, socio-cultural, biological context and relation to mental disorders.","authors":"Ewa Kurczewska, Ewa Ferensztajn-Rochowiak, Janusz Rybakowski, Filip Rybakowski","doi":"10.12740/PP/160301","DOIUrl":"https://doi.org/10.12740/PP/160301","url":null,"abstract":"<p><p>This article presents the trait of sensory processing sensitivity (SPS), its characteristics, assessment tool and association with psychiatric disorders based on an analysis of the literature on SPS since 1997. An overview of research on SPS in several relevant contexts is presented: evolutionary/adaptive, socio-cultural, temperamental/personality, and biological, taking into account the influence of genetic factors and the activity of specific areas of the central nervous system involved in processing emotional and cognitive stimuli. High sensitivity of sensory processing is an innate trait, biologically determined and modulating developmental processes, occurring in 20-35% of the general population regardless of gender. It is characterized by deeper processing of stimuli, ease of overstimulation, strong emotional reactions and empathic bonds, as well as sensitivity to subtleties in the surrounding world. SPS can be associated with susceptibility to the development of a wide range of psychiatric symptoms and disorders, including depressive and anxiety disorders, social phobia, alexithymia, burnout, internalizing and externalizing disorders and selective mutism in children.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 2","pages":"249-264"},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Psychiatria polskaPub Date : 2024-04-30DOI: 10.12740/PP/OnlineFirst/157105
Joachim Kowalski, Adam Elżanowski, Andrzej Śliwerski
{"title":"A review of selected psychotherapies for PTSD, their efficacy and treatment guidelines in adults.","authors":"Joachim Kowalski, Adam Elżanowski, Andrzej Śliwerski","doi":"10.12740/PP/OnlineFirst/157105","DOIUrl":"10.12740/PP/OnlineFirst/157105","url":null,"abstract":"<p><strong>Aim: </strong>Around 2.5% of Poles will develop post-traumatic stress disorder (PTSD) during their lifetime. Recent events, i.e. the pandemic and the war in Ukraine, are the factors that will increase the number of people dealing with PTSD. Owing to that, this paper aims to review and familiarise readers with the available scientific evidence on psychotherapies of PTSD provided in Poland.</p><p><strong>Material and methods: </strong>A review of meta-analyses of randomised controlled trials and a review of the most recent treatment guidelines concerning PTSD.</p><p><strong>Results: </strong>The best available evidence points to high efficacy of cognitive-behavioural therapy (CBT) with prolonged exposure and Eye Movement Desensitization and Reprocessing (EMDR). Humanistic therapy also proves effective to a certain degree, but not as effective as therapies that use exposure to stimuli and memories associated with trauma. There is no evidence of the efficacy of psychodynamic therapy and methods based on polyvagal theory. Organisations preparing guidelines recommend primarily CBT and EMDR.</p><p><strong>Conclusions: </strong>Efficacious treatment of PTSD should include a protocol with a component of exposure to trauma-related memories and stimuli. It is recommended to use such therapies in the psychotherapeutic treatment of PTSD.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"315-328"},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9752383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Psychiatria polskaPub Date : 2024-04-30DOI: 10.12740/PP/OnlineFirst/154806
Przemysław Cynkier
{"title":"Insanity as a consequence of an epileptic seizure and precautionary measures.","authors":"Przemysław Cynkier","doi":"10.12740/PP/OnlineFirst/154806","DOIUrl":"10.12740/PP/OnlineFirst/154806","url":null,"abstract":"<p><p>The analysis covers the case of a driver suffering from epilepsy for many years, who during an epileptic seizure, in a state of profound disturbance of consciousness, caused a road accident. Such situations usually result in the perpetrator being considered insane in relation to the allegation. The task of expert psychiatrists and psychologists is then to assess the likelihood of the perpetrator of the prohibited act repeating it, and to indicate to the court the optimal therapeutic precautionary or penal measure. These legal solutions also apply to perpetrators who were considered insane due to disturbances of consciousness occurring in the course of various somatic diseases, and not permanent mental disorders. Currently, there are no grounds for appointing expert neurologists, diabetologists, cardiologists, pulmonologists, and other specialists who would assess the legitimacy of taking precautionary measures, which may raise judicial doubts. Moreover, applying in such cases only the measures indicated in Article 93a § 1 of the Penal Code does not find any psychiatric and psychological justification. Consideration should be given to extending the catalog of protective measures to include the therapy of various somatic diseases in order to minimize the risk of developing deep mental disorders in the future. The work proposes new opinion-making solutions, which, however, requires changes in legal regulations.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"303-313"},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9727880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Psychiatria polskaPub Date : 2024-04-30Epub Date: 2024-04-09DOI: 10.12740/PP/OnlineFirst/169646
Przemysław Bieńkowski, Adam Wichniak
{"title":"Efficacy and tolerability of brexpiprazole - a new antipsychotic drug from the group of dopamine D2 receptor partial agonists.","authors":"Przemysław Bieńkowski, Adam Wichniak","doi":"10.12740/PP/OnlineFirst/169646","DOIUrl":"10.12740/PP/OnlineFirst/169646","url":null,"abstract":"<p><p>Brexpiprazole is a new antipsychotic drug from the group of dopamine D2/D3 receptor partial agonists. It represents a development of the second-generation antipsychotics and is an important addition to the pharmacological treatment options for schizophrenia. The purpose of this article is to present, illustrated by the case of brexpiprazole, how advances in the pharmacological properties of new antipsychotics translate into improved results in the treatment of schizophrenia, not only in terms of symptom reduction, but also in terms of functional improvement. The ratio of activation to blocking of the D2/D3 receptor is lower for brexpiprazole than for aripiprazole and cariprazine, which may translate into a lower risk of akathisia. Brexpiprazole has also stronger antihistaminic activity, which is likely to be associated with a stronger sedative effect, a lower risk of akathisia, excessive agitation and insomnia. Brexpiprazole meets the traditional requirements for an antipsychotic drug's efficacy, i.e., compared to placebo, it brings a greater reduction in schizophrenia symptoms in short-term studies and prevents schizophrenia relapses in long-term follow-up. The highest antipsychotic efficacy was found with the highest registered dose (4 mg/day). In addition to reducing positive symptoms, brexpiprazole treatment also leads to a reduction in negative and depressive symptoms, as well as anxiety. It has also a positive effect on patients' social and personal functioning and quality of life. This action of the drug is in line with the expectations of patients and their families regarding effective treatment. It should not only reduce symptoms, but also enable a return to health, i.e., a state that, in addition to optimal health and a sense of psychological well-being, also makes it possible to maintain proper social relations.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 2","pages":"237-248"},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Izabela Agnieszka Jaworska, Robert Pudlo, Anna Mierzyńska, Agnieszka Kuczaj, Ewa Piotrowicz, Agnieszka Biełka, Piotr Przybyłowski
{"title":"Preparation for implantation of mechanical circulatory support: psychological adjustment and treatment of mental disorders in the pre- and postoperative period.","authors":"Izabela Agnieszka Jaworska, Robert Pudlo, Anna Mierzyńska, Agnieszka Kuczaj, Ewa Piotrowicz, Agnieszka Biełka, Piotr Przybyłowski","doi":"10.12740/PP/170067","DOIUrl":"https://doi.org/10.12740/PP/170067","url":null,"abstract":"<p><p>Treatment of patients with advanced heart failure (HF) with the use of left ventricular assist devices (LVADs) improves the quality of life and the length of survival. Despite the undeniable benefits associated with improved physical performance, as a result of the decrease of the underlying disease symptoms, it carries the risk of complications in the area of the patient's somatic and psychological status. Long-term circulatory failure can contribute to a weakening of the adaptative mechanism and consequently lead to a variety of emotional disruptions. Patients must face the fear of imminent physical, family, and social changes that LVAD requires. They may experience sleep disorders, mood disorders, anxiety disorders, and in the early postoperative period also disorders of consciousness with a pattern of delirium. For this reason, it is advisable to provide multidisciplinary medical care for the patient at all stages of treatment, including regular monitoring of general health and mental health. This article presents risk factors for psychiatric disorders in patients with LVADs and ways of pharmacological and non-pharmacological management when these factors are identified and disorders are diagnosed.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 2","pages":"277-287"},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}