Psychiatria polska最新文献_第5页

Psychological functioning in patients with different PCOS phenotypes: exploring attachment styles and stress coping. 不同PCOS表型患者的心理功能：依恋方式与压力应对的探讨。

IF 1.5 4区医学

Psychiatria polska Pub Date : 2026-04-03 Epub Date: 2026-04-30 DOI: 10.12740/PP/208260

Witold Urban, Dominika Dudek, Katarzyna Klasa, Jerzy A Sobański, Olga Kacalska-Janssen, Robert Jach, Michał Mielimąka

{"title":"Psychological functioning in patients with different PCOS phenotypes: exploring attachment styles and stress coping.","authors":"Witold Urban, Dominika Dudek, Katarzyna Klasa, Jerzy A Sobański, Olga Kacalska-Janssen, Robert Jach, Michał Mielimąka","doi":"10.12740/PP/208260","DOIUrl":"https://doi.org/10.12740/PP/208260","url":null,"abstract":"Objectives: To assess attachment patterns and stress coping strategies in patients with NIH and non-NIH phenotypes of PCOS. Additionally, to explore the correlations between attachment and stress coping, as well as the correlations between BMI, hirsutism, and psychological variables.Methods: 62 patients with NIH phenotypes and 32 patients with non-NIH phenotypes were enrolled into the study. Each patient underwent gynecological and endocrinological diagnostics. Attachment Styles Questionnaire was used to assess attachment, and Mini-Cope Inventory was applied to assess stress coping.Results: The anxious-ambivalent attachment pattern was more pronounced in patients with \"classic\" NIH phenotypes. Patients with NIH phenotypes were less likely to use active coping, planning, and acceptance as coping mechanisms for stress. Furthermore, we observed a statistical trend in the differences in the following avoidance coping strategies: denial (p = 0.066), behavioral disengagement (p = 0.084), and self-blame (p = 0.066). In both phenotypes secure attachment correlated positively with seeking emotional support, whereas anxious-avoidant correlated negatively with this mechanism. In turn, anxious-ambivalent attachment in both phenotypes correlated negatively with acceptance and positively with behavioral disengagement and self-blame. Attachment patterns did not correlate with either BMI or the severity of hirsutism.Conclusions: Patients with different PCOS phenotypes differ in their attachment patterns and stress coping strategies. Attachment styles are correlated with specific coping mechanisms for stress. Personalized approach that takes into account the clinical variability of PCOS and differences in psychological functioning should be applied.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"60 2","pages":"309-322"},"PeriodicalIF":1.5,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148376828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of a day treatment program for negative symptoms in patients with schizophrenia. 精神分裂症患者阴性症状每日治疗方案的有效性

IF 1.5 4区医学

Psychiatria polska Pub Date : 2026-03-30 DOI: 10.12740/PP/207886

Dawid Kruk, Aneta Kalisz, Piotr Błądziński, Artur Daren, Iga Plencler, Andrzej Cechnicki

{"title":"Effectiveness of a day treatment program for negative symptoms in patients with schizophrenia.","authors":"Dawid Kruk, Aneta Kalisz, Piotr Błądziński, Artur Daren, Iga Plencler, Andrzej Cechnicki","doi":"10.12740/PP/207886","DOIUrl":"10.12740/PP/207886","url":null,"abstract":"Objectives: To evaluate the effectiveness of a day treatment program in reducing primary negative symptoms in people with schizophrenia and to identify predictors of treatment response.Methods: This study was conducted at the Day Treatment and Rehabilitation Centre for people suffering from psychosis. Forty-three participants were assessed using PANSS, BNSS, CDSS, MOCA and FAB scales before and after 3 months of treatment. The therapeutic program included individual and group psychotherapy, social skills training, psychoeducation, music therapy, movement therapy, art therapy, occupational therapy, therapeutic community meetings, family sessions, and therapeutic excursions.Results: Participants showed a significant decrease in negative symptoms and depressive symptoms following treatment. Improvement was observed in all five domains of negative symptoms. Regression analysis showed that intact motor programming skills were a significant predictor of improvement in negative symptoms. Improvement in insight correlated with better treatment outcomes.Conclusions: The day treatment program was effective in treating primary negative symptoms in all five domains. Further research with a larger sample size and a control group is needed.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"60 1","pages":"145-160"},"PeriodicalIF":1.5,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147864385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A combination of xanomeline with trospium as an innovative pharmacological strategy for schizophrenia. xanomeline联合trospium作为一种治疗精神分裂症的创新药物策略。

IF 1.5 4区医学

Psychiatria polska Pub Date : 2026-02-28 DOI: 10.12740/PP/199877

Alicja Zakrzewska-Sito, Julita Kuczyńska

{"title":"A combination of xanomeline with trospium as an innovative pharmacological strategy for schizophrenia.","authors":"Alicja Zakrzewska-Sito, Julita Kuczyńska","doi":"10.12740/PP/199877","DOIUrl":"10.12740/PP/199877","url":null,"abstract":"Treating schizophrenia involves many difficulties. It is estimated that around 20-33% of patients do not respond to the proposed therapy with available antipsychotic drugs, which is associated with the occurrence of problems with everyday functioning. Currently used drugs are mainly characterized by regulation of the dopaminergic system. This review compiles information on the effectiveness of a complex drug (xanomeline with trospium) for schizophrenia with a new mechanism of action. The drug, known as KarXT, targets proteins in the brain known as muscarinic receptors. Activation of these receptors suppresses the release of the neurotransmitter dopamine, whose deficiency is associated with the occurrence of key symptoms of schizophrenia, such as hallucinations and delusions. The drug offers hope for better efficacy in treating schizophrenia and better tolerability than current therapies. On September 27, 2024, the FDA approved Cobenfy (known as KarXT - xanomeline with trospium), a new oral medication for adults with schizophrenia. The approval of Cobenfy is a landmark moment in the treatment of schizophrenia because it offers a new, innovative treatment option for this challenging condition.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"60 1","pages":"37-52"},"PeriodicalIF":1.5,"publicationDate":"2026-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147864353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The negative consequences of indirect trauma exposure in professionals - the psychometric properties of the Secondary Traumatic Stress Inventory. 间接创伤暴露对专业人员的负面影响——二次创伤应激量表的心理测量特性。

IF 1.5 4区医学

Psychiatria polska Pub Date : 2026-02-28 DOI: 10.12740/PP/199482

Ogińska-Bulik Nina, Zygfryd Juczyński

{"title":"The negative consequences of indirect trauma exposure in professionals - the psychometric properties of the Secondary Traumatic Stress Inventory.","authors":"Ogińska-Bulik Nina, Zygfryd Juczyński","doi":"10.12740/PP/199482","DOIUrl":"10.12740/PP/199482","url":null,"abstract":"Objectives: The Secondary Traumatic Stress Inventory (STSI), which is a modified version of the PTSD Symptom List (PCL-5), is designed to assess the symptoms of secondary traumatic stress in professionals working with traumatized individuals. The aim of the study was to determine the psychometric properties of the STSI and establish diagnostic criteria allowing for the assessment of the severity of disorders following secondary traumatic stress.Methods: The research was conducted among 900 people representing eight occupational groups exposed to secondary trauma. In total, data from 810 participants was analyzed, the majority of whom (64%) were women. The mean age of the subjects was 43.9 years (SD = 9.60). The STSI was performed in conjunction with several other measurement tools.Results: STSI is characterized by a high reliability index (Cronbach's alpha = 0.94). Four factors were found to correspond to the main criteria of post-traumatic stress disorders, viz. intrusions, avoidance, changes in cognition and emotions, and increased arousal and reactivity. The confirmatory analysis confirmed the validity of adopting the four-factor structure. A cut-off point of 33 was found to be predictive of possible disorders after secondary traumatic stress. The highest risk of disorders was noted among medical personnel, the lowest among therapists and police officers.Conclusions: STSI is an accurate and reliable tool for assessing secondary traumatic stress and can be used both in research and clinical practice as a predictor of disorders after secondary traumatic stress.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"60 1","pages":"77-90"},"PeriodicalIF":1.5,"publicationDate":"2026-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147864367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current challenges in pharmacotherapy of depression in children and adolescents - a contemporary perspective. 当前儿童和青少年抑郁症药物治疗的挑战-当代视角。

IF 1.5 4区医学

Psychiatria polska Pub Date : 2026-02-28 DOI: 10.12740/PP/200518

Agnieszka Dominika Jaros, Agnieszka Słopień, Filip Rybakowski, Edmund Grześkowiak, Agnieszka Bienert

{"title":"Current challenges in pharmacotherapy of depression in children and adolescents - a contemporary perspective.","authors":"Agnieszka Dominika Jaros, Agnieszka Słopień, Filip Rybakowski, Edmund Grześkowiak, Agnieszka Bienert","doi":"10.12740/PP/200518","DOIUrl":"10.12740/PP/200518","url":null,"abstract":"Depression is becoming an increasingly significant challenge for public and societal health, affecting both adults and children and adolescents worldwide. Diagnosis is based on identifying five characteristic symptoms persisting for at least two weeks. Diagnosing children may be more challenging due to the masking of symptoms in behavioral patterns. Treatment mainly involves medications such as selective serotonin reuptake inhibitors (SSRIs), but due to limited availability of approved drugs, off-label use is often resorted to. Fluoxetine is an important drug in the treatment of depression in children, showing efficacy and good tolerability. However, patients should be monitored for suicidal thoughts. Sertraline, although not registered for the treatment of depression in children, is often used off-label and shows a positive response to treatment. Escitalopram, approved for the treatment of depression in children over 12 years of age, is stronger and more selective than citalopram, but its approval is based on limited clinical trials. Children and adolescents have different pharmacokinetic and pharmacodynamic profiles, requiring a personalized approach to therapy. Therapy monitored by drug concentration in the blood (TDM) is an important tool for adjusting the dose to the patient's needs. The role of pharmacists in monitoring antidepressant therapy in children and adolescents is valuable and can contribute to improved clinical outcomes. The article analyzes the efficacy and safety of antidepressant drugs in children and adolescents, with an emphasis on SSRIs, and identifies issues related to therapy selection, with particular emphasis on personalized care and the growing role of TDM in optimizing treatment outcomes.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"60 1","pages":"21-36"},"PeriodicalIF":1.5,"publicationDate":"2026-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147864312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The use of vortioxetine in the treatment of depression following the failure of therapy with a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor. 选择性5 -羟色胺再摄取抑制剂或5 -羟色胺-去甲肾上腺素再摄取抑制剂治疗失败后使用沃替西汀治疗抑郁症。

IF 1.1 4区医学

Psychiatria polska Pub Date : 2026-02-28 DOI: 10.12740/PP/OnlineFirst/197146

Adam Wichniak, Marcin Iwański, Matija Mitrić

{"title":"The use of vortioxetine in the treatment of depression following the failure of therapy with a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor.","authors":"Adam Wichniak, Marcin Iwański, Matija Mitrić","doi":"10.12740/PP/OnlineFirst/197146","DOIUrl":"10.12740/PP/OnlineFirst/197146","url":null,"abstract":"Up to 40% of patients with depression do not respond to first-line treatment and among those who do respond, only about half achieve remission. For this reason, guidelines for treating depression mainly focus on how to proceed in cases of treatment failure or only partial response. The aim of this review paper is to present studies evaluating the effectiveness of vortioxetine in treatment of patients with depression following treatment failure with an SSRI/SNRI drug. Vortioxetine is an effective antidepressant that, after treatment failure with an SSRI/SNRI drug, allows 32-55% of patients to achieve remission. However, the assessed dosing regimen of vortioxetine deviated from that used in the initial therapy of depression, i.e. by the second week (8th day) of therapy the dose was increased to the maximum - 20 mg/day and the period for treatment effectiveness assessment was 8-12 weeks. This dosing regimen more closely resembles the pharmacological approach utilised in the treatment of obsessive-compulsive disorder rather than depression. The administration of a high dose of vortioxetine did not negatively impact the tolerability of the treatment, even among patient groups at high risk of adverse events (elderly patients, co-existence of anxiety). The most common adverse effect was nausea; however, it was not observed that rapid dose escalation intensified this effect. This is most likely attributable to the receptor profile of vortioxetine.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"7-20"},"PeriodicalIF":1.1,"publicationDate":"2026-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case report: Could hikikomori be a specific presentation of psychotic decompensation in people with autism spectrum disorder? 病例报告：“隐蔽青年”是否可能是自闭症谱系障碍患者精神代偿失调的一种特殊表现？

IF 1.5 4区医学

Psychiatria polska Pub Date : 2026-02-28 DOI: 10.12740/PP/197225

Karolina Anna Dąbrowska, Krzysztof Maria Wilczyński, Karolina Zofia Kamińska, Małgorzata Janas-Kozik

{"title":"Case report: Could hikikomori be a specific presentation of psychotic decompensation in people with autism spectrum disorder?","authors":"Karolina Anna Dąbrowska, Krzysztof Maria Wilczyński, Karolina Zofia Kamińska, Małgorzata Janas-Kozik","doi":"10.12740/PP/197225","DOIUrl":"10.12740/PP/197225","url":null,"abstract":"The phenomenon of \"hikikomori\" is characterized by spending most of the day in one room, visibly avoiding social situations and interpersonal relationships, and leaving one's room only at night so as not to be noticed by others, and spending a lot of time surfing the Internet or playing video games. Although first described in Japan, cases have been described from around the world. Studies on hikikomori available in the literature indicate a wide range of disorders diagnosed in this group of patients such as anxiety disorders, personality disorders, mood disorders, and psychotic disorders. However, it is most often observed with ASD (autism spectrum disorder). The aim of this study is to consider hikikomori as a specific presentation of psychotic decompensation in people with ASD. In the case of a 10-year-old boy with ASD, sulpiride brought an improvement in social withdrawal, which, together with the symptoms presented by him, may indicate the possibility of psychotic decompensation in the form of hikikomori. Due to the lack of therapeutic guidelines for the management of people with hikikomori, this may be a valuable guideline for the implementation of appropriate pharmacotherapy by clinicians, in which attention should also be paid to frequently occurring other psychiatric disorders.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"60 1","pages":"61-75"},"PeriodicalIF":1.5,"publicationDate":"2026-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147864395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial. 社论。

IF 1.5 4区医学

Psychiatria polska Pub Date : 2026-02-28 DOI: 10.12740/PP/218999

Dominika Dudek, Jerzy A Sobański, Katarzyna Klasa

引用次数: 0

Religious singing as an unusual sign of craniopharyngioma. Case report and literature review. 宗教歌唱是颅咽管瘤的不寻常征兆。病例报告及文献复习。

IF 1.5 4区医学

Psychiatria polska Pub Date : 2026-02-28 DOI: 10.12740/PP/196060

Michał Senger, Tomasz Andrzej Dziedzic, Aleksandra Bala, Magdalena Góralska, Przemysław Kunert

{"title":"Religious singing as an unusual sign of craniopharyngioma. Case report and literature review.","authors":"Michał Senger, Tomasz Andrzej Dziedzic, Aleksandra Bala, Magdalena Góralska, Przemysław Kunert","doi":"10.12740/PP/196060","DOIUrl":"10.12740/PP/196060","url":null,"abstract":"Craniopharyngiomas are rare and benign intracranial tumours arising in the sellar region. Typically, patients with craniopharyngioma present with headaches, visual disturbances and endocrine deficits due to compression of adjacent proximal structures. Primary psychiatric clinical presentation has been rarely reported. We present the case of a 59-year-old female with craniopharyngioma with suprasellar extension into the third ventricle and a clinical picture dominated by behavioural changes. Due to mental disturbances, the patient was diagnosed and underwent initial surgical treatment in another medical facility. She was admitted to our Department due to a mental disorder relapse attributed to tumour regrowth. On admission, she was singing religious songs spontaneously or in response to questions, and neuropsychological examination revealed disturbances of memory, attention, executive functioning and decreased drive. The patient was scheduled for reoperation. Following subtotal resection, she was discharged home without psychiatric symptoms. Two years later, after initial improvement, the patient was readmitted with the same mental disorder and tumour regrowth. She underwent a second reoperation and was discharged with improved mental status. After a 2-month follow-up period, the patient's family reported a complete resolution of behavioural disturbances. Based on the literature review and our observation, we assume that the psychiatric manifestation of craniopharyngioma might be associated with dysfunction of suprasellar structures, namely the hypothalamus, and in such cases, resection should be carried out to the maximum safe extent.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"60 1","pages":"53-60"},"PeriodicalIF":1.5,"publicationDate":"2026-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147864326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Internet-based cognitive-behavioral therapy for obsessive-compulsive disorder - a literature review. 基于网络的强迫症认知行为疗法——文献综述。

IF 1.5 4区医学

Psychiatria polska Pub Date : 2026-02-28 DOI: 10.12740/PP/199368

Marta Kuty-Pachecka

{"title":"Internet-based cognitive-behavioral therapy for obsessive-compulsive disorder - a literature review.","authors":"Marta Kuty-Pachecka","doi":"10.12740/PP/199368","DOIUrl":"10.12740/PP/199368","url":null,"abstract":"Obsessive-compulsive disorder (OCD) is a condition in which the key symptoms are obsessive thoughts and motor compulsions. The prevalence of obsessive-compulsive disorder is about 2-3%. The issue of the effectiveness of internet-based therapeutic interventions based on cognitivebehavioral therapy (iCBT) for people suffering from obsessive-compulsive disorder (OCD) has not been thoroughly investigated in Poland yet. The aim of this article is to present the results of existing studies on sample iCBT programs for people with OCD and to analyze their effectiveness. In addition to reviewing the conducted research on the therapeutic effectiveness of iCBT, we also presented the results of analyses of the main predictive factors that may influence the effectiveness of internet-based cognitive behavioral therapy when working with patients with OCD. The following scientific databases were reviewed in search for relevant literature: PubMed/MEDLINE, Web of Science, and EBSCO. The presented study is a review of works published in the last 15 years (from 2010 to 2024). The following key words were used while searching for relevant articles: icbt, internet based cognitive behavioral therapy; internet cognitive behavioral therapy; internet-based intervention ocd; internet-delivered cognitive behavior therapy, and ocd, obsessive compulsive disorder, obsessive-compulsive symptoms. Eventually 38 research papers were selected for further analysis. The initial research suggests that fully automated iCBT programs, as well as those including therapist support, are promising approaches to working with patients and are an effective way to increase access to treatment for people with OCD.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"60 1","pages":"105-128"},"PeriodicalIF":1.5,"publicationDate":"2026-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147864356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0