Psychiatria polska最新文献

{"title":"Long-term effects and the mediating role of coping styles between behavioral changes and psychopathological responses among Polish university students during the COVID-19 pandemic.","authors":"Karolina Fila-Pawłowska, Dorota Szcześniak, Patryk Piotrowski, Agata Justyna Kołodziejczyk, Mateusz Łuc, Emilia Pawłowska, Marta Rymaszewska, Joanna Rymaszewska","doi":"10.12740/PP/OnlineFirst/195284","DOIUrl":"https://doi.org/10.12740/PP/OnlineFirst/195284","url":null,"abstract":"<p><strong>Objectives: </strong>Students have been indicated as an at-risk group for developing poorer psychological responses and decreased well-being during the COVID pandemic. The aim of the study was to observe a trajectory of lifestyle changes and its impact on mental health in longitudinal perspective as well as explore the coping strategies used by students during the pandemic and their possible mediating effect on psychopathological symptoms.</p><p><strong>Methods: </strong>Data were collected via an online survey addressing behavioral changes that occur during the pandemic, as well as psychopathological and PTSD symptoms. It was conducted among university students at two time-points May and June 2020 as well as June and October 2021 with a pooled total number of participants n=2010.</p><p><strong>Results: </strong>the studied population of Polish university students has experienced significant behavioral and psychological changes due to the COVID-19 pandemic which remained influential after over a year into the crisis.</p><p><strong>Conclusions: </strong>Previously drawn conclusions regarding risk factors were confirmed - all of the variables associated with worse mental health in the beginning of the pandemic remained significantly related to higher psychopathology and PTSD symptoms over a year later. Partial mediations between all of the explored coping strategies, behavioral changes and psychopathological symptoms could be established.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"1-25"},"PeriodicalIF":0.9,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minority stress and the psychological well-being of non-heteronormative people: The mediating role of internal dialogues.","authors":"Małgorzata M Puchalska-Wasyl, Izabela Jaroszek","doi":"10.12740/PP/OnlineFirst/199788","DOIUrl":"https://doi.org/10.12740/PP/OnlineFirst/199788","url":null,"abstract":"<p><strong>Objectives: </strong>Non-heteronormative people experience minority stress, which co-occurs with suicidal thoughts, symptoms of depression, lower self-esteem, and low life satisfaction. The aim of the article is to establish the relationship between minority stress experienced by these people and their psychological well-being, and to determine whether internal dialogues mediate this relationship.</p><p><strong>Methods: </strong>130 non-heterosexual people aged 18-46 were studied. In addition to the sociodemographic survey, the Minority Stress Scale (MSS), the Functions of Dialogues - Revised Questionnaire (FUND-R) and the Psychological Well-Being Scale (PWBS) were used.</p><p><strong>Results: </strong>It was found that psychological well-being correlates negatively with aspects of minority stress - expectation of rejection and hiding, but positively with the level of self-disclosure and satisfaction with self-disclosure. Ruminative dialogues mediate the negative relationships between the expectation of rejection and well-being as well as between hiding and well-being, while self-knowing dialogues mediate positive relationships between the level of disclosure and well-being as well as between satisfaction with disclosure and well-being.</p><p><strong>Conclusions: </strong>In order to improve the well-being of non-heteronormative patients/clients experiencing minority stress, in psychological or psychiatric practice it is worth reducing their ruminative dialogues and replacing them with self-knowing dialogues.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"1-15"},"PeriodicalIF":0.9,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotional conscience in individuals with affective disorders.","authors":"Roksana Epa, Katarzyna Olszewska-Turek, Anna Rajtar, Barbara Bętkowska-Korpała, Dominika Dudek","doi":"10.12740/PP/OnlineFirst/186661","DOIUrl":"https://doi.org/10.12740/PP/OnlineFirst/186661","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the study was to analyse the functioning of emotional conscience in individuals with mood disorders, taking into account the differences between patients with recurrent depression and patients with bipolar disorder. The dependence of the susceptibility to experiencing particular moral feelings on the symptoms of the illness - both on their type and severity - was also a subject of consideration.</p><p><strong>Methods: </strong>Results from 131 subjects were analysed, including 44 patients with bipolar disorder, 33 patients with recurrent depression and 54 individuals without a diagnosis of mental disorders. More women (67%) than men (33%) took part in the study, the average age of the respondents was 43 years. The following research methods were used: the Hamilton Depression Rating Scale (HAM-D), the Young Mania Rating Scale (YMRS) and the Moral Feelings Scale (SUM-5).</p><p><strong>Results: </strong>Statistically significant differences were observed between the examined groups in the functioning of emotional conscience assessed using the SUM-5. Patients with mood disorders described themselves as experiencing some of the distinguished moral emotions with different susceptibility than healthy individuals. Similarly, different experiencing of these types of feelings was noticed in groups of patients with recurrent depression and bipolar disorder. The dependence of the functioning of their emotional conscience on the type and severity of experienced symptoms, assessed on the HAM-D and YMRS scales, was also noted.</p><p><strong>Conclusions: </strong>The emotional conscience of people with mood disorders may have specific features, that are less pronounced in healthy subjects. Taking this into account seems to be an important aspect of understanding patients, helpful when building a healing relationship with them.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"1-17"},"PeriodicalIF":0.9,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of vortioxetine in the treatment of depression following the failure of therapy with a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor.","authors":"Adam Wichniak, Marcin Iwański, Matija Mitrić","doi":"10.12740/PP/OnlineFirst/197146","DOIUrl":"https://doi.org/10.12740/PP/OnlineFirst/197146","url":null,"abstract":"<p><p>Up to 40% of patients with depression do not respond to first-line treatment and among those who do respond, only about half achieve remission. For this reason, guidelines for treating depression mainly focus on how to proceed in cases of treatment failure or only partial response. The aim of this review paper is to present studies evaluating the effectiveness of vortioxetine in treatment of patients with depression following treatment failure with an SSRI/SNRI drug. Vortioxetine is an effective antidepressant that, after treatment failure with an SSRI/SNRI drug, allows 32-55% of patients to achieve remission. However, the assessed dosing regimen of vortioxetine deviated from that used in the initial therapy of depression, i.e. by the second week (8th day) of therapy the dose was increased to the maximum - 20 mg/day and the period for treatment effectiveness assessment was 8-12 weeks. This dosing regimen more closely resembles the pharmacological approach utilised in the treatment of obsessive-compulsive disorder rather than depression. The administration of a high dose of vortioxetine did not negatively impact the tolerability of the treatment, even among patient groups at high risk of adverse events (elderly patients, co-existence of anxiety). The most common adverse effect was nausea; however, it was not observed that rapid dose escalation intensified this effect. This is most likely attributable to the receptor profile of vortioxetine.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"1-14"},"PeriodicalIF":0.9,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental minority stress and symptoms of depression and anxiety in women raising children in same-sex relationships.","authors":"Jowita Wycisk, Marzenna Zakrzewska","doi":"10.12740/PP/OnlineFirst/190770","DOIUrl":"https://doi.org/10.12740/PP/OnlineFirst/190770","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this study was to examine the levels of depression and anxiety of lesbian and bisexual (LB) mothers raising children from a previous heterosexual relationship in a current same-sex relationship, on the basis of minority stress theory.</p><p><strong>Methods: </strong>58 LB biological mothers, 33 LB co-mothers from same-sex relationships and 60 mothers from different-sex marriages participated in a questionnaire-based online survey. The groups were compared in terms of depression and anxiety severity (state and trait). In the LB groups, correlation analysis was conducted between the dependent variables and the number of encountered negative homophobic events, the expectation of rejection, self-concealment, and internalised homophobia. To examine whether the associations between these variables in LB biological mothers and co-mothers differed, moderation analysis was used.</p><p><strong>Results: </strong>The levels of depression and anxiety were similar across the groups. Among LB mothers, anxiety (state and trait) correlated mainly with internalised homophobia, whereas depression was linked to the expectation of rejection. Notably, among biological LB mothers, as opposed to co-mothers, there was an association between both depression and anxiety (state) and negative homophobic events.</p><p><strong>Conclusions: </strong>The lack of intergroup differences in levels of depression and anxiety, with correlations of these variables with minority stress, may indicate high resources (e.g. family resilience) of LB mothers. The cost of homophobic events is higher for LB biological mothers than for LB co-mothers. This may be attributed to the later emergence of non-heterosexual identity in LB biological mothers who have children from heteronormative relationships, leading to a heightened sense of threat when their custody rights are challenged.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"1-14"},"PeriodicalIF":0.9,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effectiveness of medical education in schizophrenia depending on the mental state and type of treatment in forensic psychiatric patients.","authors":"Joanna Fojcik, Tomasz Sobierajski, Michał Górski, Ewa Martyniak, Agnieszka Borowska, Marek Krzystanek","doi":"10.12740/PP/OnlineFirst/193181","DOIUrl":"https://doi.org/10.12740/PP/OnlineFirst/193181","url":null,"abstract":"<p><strong>Objectives: </strong>The main objective of the study was to answer the question of whether the clinical condition of the patient and the type of antipsychotic drug used affect the educational opportunities of patients hospitalised in forensic psychiatry departments participating in a health education programme.</p><p><strong>Methods: </strong>The study was conducted at the State Hospital for the Mentally and Neurologically Ill in Rybnik in the forensic psychiatry wards and lasted from December 2019 to May 2020. During the study, patients gained knowledge of health education. The study group consisted of 67 men aged 22-73 with a diagnosis of schizophrenia. The control group consisted of 40 patients aged 23-72 with the same diagnosis who were not educated. A dual measurement method was used (before and after the health education cycle) using the CGI-S scale and a proprietary questionnaire of patients' knowledge from the applied educational programme.</p><p><strong>Results: </strong>The study showed that the severity of mental illness symptoms had a significant impact on patients' educational opportunities. The variety of antipsychotic medications used (atypical and classic) did not affect patients' educational opportunities. In addition, the study showed that the educational level of the patients had a significant impact on their educational opportunities.</p><p><strong>Conclusions: </strong>The effectiveness of educational interventions depends on the severity of symptoms in patients diagnosed with schizophrenia, but does not depend on the type of pharmacotherapy used.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"1-22"},"PeriodicalIF":0.9,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of mycelia derived from in vitro cultures of Amanita spp. as a potential source of bioactive compounds with therapeutic potential for the mitigation and management of depressive disorders.","authors":"Katarzyna Kała, Katarzyna Sułkowska-Ziaja, Joanna Piotrowska, Marta Gajda, Agnieszka Sękara, Kamil Hnatyk, Jan Lazur, Bożena Muszyńska","doi":"10.12740/PP/OnlineFirst/193251","DOIUrl":"https://doi.org/10.12740/PP/OnlineFirst/193251","url":null,"abstract":"<p><strong>Objectives: </strong>Mushrooms of the Amanita genus are considered among the most toxic, causing severe poisoning, often resulting in death. However, of the 707 described species within this genus, only around a dozen contain the toxic octapeptides classified as amanitotoxins and phallotoxins. While most representatives of the genus are considered inedible species, there are a few exceptions that are palatable edible species. Amanita muscaria and Amanita pantherina fall into the category of poisonous species, with significant ethnomycological impact on human evolution and sociology, alongside their other psychoactive effects. This study aimed to obtain mycelium of A. muscaria and A. pantherina species under controlled laboratory conditions, using 10 L air-lift bioreactors and to evaluate the obtained material as a potential pharmaceutical raw material containing muscimol and other biologically active compounds of importance, which may have significance in the prevention of depression.</p><p><strong>Methods: </strong>The resulting biomass was analyzed by RP-HPLC and AAS to identify various organic compounds (indole compounds, sterols, lovastatin, ergothioneine, muscimol, and ibotenic acid) and different bioelements.</p><p><strong>Results: </strong>Based on the results obtained, it can be concluded that the mycelium of A. muscaria contains several bioactive compounds, such as lovastatin, ergothioneine, and 5-hydroxy-L-tryptophan, at higher levels than A. pantherina.</p><p><strong>Conclusions: </strong>The determination of muscimol and other bioactive substances, which have not been previously studied, in the biomass obtained through in vitro cultivation, compared to those found in the fruiting bodies, suggests the potential of these species in the treatment of depression. However, further research, including in vitro experiments and subsequent clinical trials, is required.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"1-16"},"PeriodicalIF":0.9,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Borderline personality - from psychoanalysis to epigenetics. Biological basis of attachment.","authors":"Małgorzata Juraś-Darowny, Dominik Strzelecki, Monika Talarowska","doi":"10.12740/PP/OnlineFirst/166492","DOIUrl":"10.12740/PP/OnlineFirst/166492","url":null,"abstract":"<p><p>In terms of object relations theory, borderline personality disorder (BPD) is characterized by a structural abnormality of identity, conflicting representations of self and others, and disorganization of attachment - a construct rooted in an individual's early experiences and central to the relationships established later in life. A special role in the formation of attachment style is attributed to the relationship with the caregiver and to difficult experiences or traumas from early developmental stages. These experiences not only provide the psychological basis for the development of an insecure attachment style, but also leave a biological mark in the body in the form of epigenetic modifications. Although research on epigenetic modifications in BPD is scarce, a growing body of evidence supports the importance of oxytocin - the \"social peptide\" underlying attachment - in the etiology of BPD. We believe that the study of epigenetic modifications that affect the action of oxytocin in the BPD clinical population will provide a better understanding of the basis and process of development of the disorder, as well as provide a therapeutic direction to work effectively in the major areas of BPD.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"997-1011"},"PeriodicalIF":0.9,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41179741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First-episode psychosis requiring electroconvulsive therapy following SARS-CoV-2 infection - Description of two cases.","authors":"Patryk Rodek, Barbara Alli-Balogun, Krzysztof Kucia","doi":"10.12740/PP/186429","DOIUrl":"10.12740/PP/186429","url":null,"abstract":"<p><p>COVID-19 is a systemic disease. Since the beginning of the pandemic, there have been increasing reports of neuropsychiatric complications of the infection. The excessive inflammatory response during the infection induces changes in neurotransmission, which can result in nonspecific manifestations of affective and psychotic disorders, among other symptoms. We present descriptions of two cases involving previously untreated psychiatric patients, in whom the first-episode psychosis occurred immediately after SARS-CoV-2 infection. The commonality between both cases, besides the preceding SARS-CoV-2 infection, was the nonspecific and highly variable course of the psychotic disorder episode. This led to numerous diagnostic challenges and the necessity to change the diagnosis during treatment for both patients. In the case of a 58-year-old woman, persistent delusional disorders were initially diagnosed, followed by organic affective disorders. However, the evolution of symptoms ultimately led to the diagnosis of severe psychotic depression. In the case of a 68-year-old man, initially diagnosed psychotic depression turned out to be a first-episode of late-onset schizophrenia. Due to significant symptom exacerbation and evident treatment resistance, electroconvulsive therapy was implemented, resulting in complete symptomatic and functional remission. The first-episode psychosis post-COVID-19 is a newly emerging complication of infection, increasingly reported but still poorly defined and described in the literature. It appears to exhibit significant differences from previously encountered disease entities. The described cases underscore the ongoing need to consider a history of SARS-CoV-2 infection as a precipitating factor for first-episode psychoses, as it can impact both the course of the illness and diagnostic and therapeutic decisions.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 6","pages":"947-955"},"PeriodicalIF":0.9,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial.","authors":"Dominika Dudek, Jerzy A Sobański, Katarzyna Klasa","doi":"10.12740/PP/200299","DOIUrl":"10.12740/PP/200299","url":null,"abstract":"<p><p>No summary.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 6","pages":"915-916"},"PeriodicalIF":0.9,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}