Psychiatria polska最新文献

{"title":"Prevalence and determinants of psychotropic medication use in Poland.","authors":"Agnieszka Pisarska, Jakub Stokwiszewski, Jacek Moskalewicz","doi":"10.12740/PP/OnlineFirst/159734","DOIUrl":"10.12740/PP/OnlineFirst/159734","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the study was to assess the prevalence of psychotropic medication use among adult population in Poland in past 12 months, and to analyse the relationship between psychotropic medication use and sociodemographic factors as well as mental health disorders experienced by respondents.</p><p><strong>Methods: </strong>Composite International Diagnostic Instrument (WHO CIDI 3.0) was used in Polish survey of general population aged 18-64. Respondents were randomly selected from the population register. Ten thousand interviews were completed with a response rate of 50,4%.</p><p><strong>Results: </strong>In the general population, psychotropic medicines were used by almost 5% of the respondents in the past 12 months. These medicines were used more often by women, respondents from the oldest age group, with low level of education, retirees, unemployed, singles and residents of small and large cities. Among those experiencing mental health problems in the past 12 months, psychotropic medications were taken by up to 17% of the respondents. Pharmacological treatment was most often endorsed by over 40% of persons with symptoms of major depression and any mood disorders, while approximately 25% of respondents with major depression confirmed antidepressant use. Gender differences were small and mostly insignificant.</p><p><strong>Conclusions: </strong>The results indicate the need to improve access to mental health treatment and to educate better general practitioners (GPs) for appropriate diagnosing and treatment of mental health disorders.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"619-636"},"PeriodicalIF":0.9,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10031045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dopamine D2 receptor partial agonists in the treatment of schizophrenia -example of brexpiprazole.","authors":"Katarzyna Maria Bliźniewska-Kowalska, Piotr Gałecki","doi":"10.12740/PP/174593","DOIUrl":"https://doi.org/10.12740/PP/174593","url":null,"abstract":"<p><p>Since the 1950s, there have been rapid developments in psychiatric pharmacotherapy, resulting not only in more effective treatment of patients, but also in improvements in minimizing adverse effects of therapy. Modern third-generation antipsychotics, in addition to antagonism toward D2 receptors, also exhibit partial agonism toward dopamine receptors. Such a mechanism of action is intended to regulate dopaminergic transmission - inhibit (antagonism) it in pathways where it is excessive (excessive transmission in the mesolimbic pathway in psychotic patients, excessive transmission in the tuberoinfundibular pathway in patients with hyperprolactinemia) and stimulate (agonism) it in pathways where it is too low (mesocortical pathway). This has a beneficial effect on both the reduction of adverse symptoms and the negative, affective and cognitive symptoms of patients suffering from schizophrenia. The purpose of this review article is to present the most important clinical aspects of the use of dopamine D2 receptor partial agonists in the treatment of schizophrenia, using brexpiprazole as an example, and to define the profile of patients to whom this drug could be dedicated - based on recent studies.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 4","pages":"581-593"},"PeriodicalIF":0.9,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there a relationship between resting state connectivity within large-scale functional networks and implicit motor learning impairments in schizophrenia and bipolar disorder?","authors":"Adrian Andrzej Chrobak, Sylwia Bielak, Dominik Nowaczek, Aleksandra Żyrkowska, Krzysztof Styczeń, Anna Maria Sobczak, Magdalena Fafrowicz, Amira Bryll, Tadeusz Marek, Dominika Dudek, Marcin Siwek","doi":"10.12740/PP/OnlineFirst/192464","DOIUrl":"https://doi.org/10.12740/PP/OnlineFirst/192464","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this exploratory study is to evaluate whether implicit motor learning impairments observed in schizophrenia (SZ) and bipolar disorder (BD) are associated with the resting state functional connectivity (rs-FC) within large-scale functional networks.</p><p><strong>Methods: </strong>The study involved 30 BD patients, 30 SZ patients and 30 healthy controls (HC). Implicit motor learning was evaluated with the use of serial reaction time task (SRTT). Prior to the training patients underwent resting state functional magnetic resonance imaging (rsfMRI) examination. We have measured rs-FC within salience network (SAN), default mode network (DMN), frontoparietal network (FPN), sensorimotor network (SMN), limbic network (LN) and visual network (VIN) and their associations with implicit motor learning indices.</p><p><strong>Results: </strong>rs-FC within SAN, DMN, FPN, SMN, LN and VIN reveal no significant association with implicit motor learning indices. BD, SZ and HC groups did not differ in terms of rs-FC within abovementioned networks.</p><p><strong>Conclusions: </strong>We have shown that in the studied groups SRTT performance could not be predicted by rs-FC within the major large-scale functional networks, i.e., SMN, FPN, VIN, LN, SAN and DMN. The observation of the independence of implicit motor learning from the initial activity of these systems is important for proper understanding of neuronal underpinnings of this process and planning further neuroimaging research on this topic.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"1-12"},"PeriodicalIF":0.9,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormalities in the absolute power of Delta and Alpha rhythms in the frontal lobe of patients suffering from psychosomatic disorders.","authors":"Łukasz Bartosz Grabowski, Marek Chełstowski, Maja Hiszpańska, Kamila Łaszewska, Monika Lewandowska, Rafał Milner","doi":"10.12740/PP/OnlineFirst/186755","DOIUrl":"https://doi.org/10.12740/PP/OnlineFirst/186755","url":null,"abstract":"<p><strong>Objectives: </strong>Psychosomatic disorders (somatic symptom disorder - SSD) constitute a heterogeneous group of medical conditions characterized by somatic symptoms without explained somatic causes. Due to the complexity of symptoms, they present a significant medical, social and economic challenge, and diagnosing and treating these disorders remains a substantial clinical challenge. The aim of the conducted research was an attempt to identify characteristic patterns in the surface-level brain bioelectrical activity of individuals experiencing psychosomatic disorders. The obtained results may contribute to understanding the pathomechanism of these disorders and developing objective methods for diagnosis and differentiation of functional dysfunctions.</p><p><strong>Methods: </strong>The study involved a group of 49 individuals: 30 patients with somatic symptom disorder (SSD) and 19 individuals in the control group. Resting-state EEG signals were recorded from the subjects under two experimental conditions (eyes open, eyes closed). The recorded signals underwent quantitative EEG (QEEG) analysis followed by statistical analysis.</p><p><strong>Results: </strong>EEG signal analysis revealed statistical differences between the studied groups in terms of absolute power in the Alpha band (8-12 Hz) in frontal areas (electrodes F3, Fz, F4) under eyes-open conditions, as well as in the Delta band (1-4 Hz) in the right frontal area (electrode F4) under eyes-closed conditions. Similar changes were not observed in the Beta (12-25 Hz) or High Beta (25-30 Hz) bands.</p><p><strong>Conclusions: </strong>The detected abnormalities in the surface-level brain bioelectrical activity may indicate potential disturbances in the reception and interpretation of visceral sensations in patients with psychosomatic disorders. The lack of differences in higher frequencies could be helpful in the differential diagnosis between these disorders and other anxiety disorders where psychosomatic symptoms are observed. The obtained results could also be useful in planning protocols involving various neurotherapeutic methods.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"1-12"},"PeriodicalIF":0.9,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical experience with parenteral trazodone in mood disorders: A literature review.","authors":"Calogero Crapanzano, Ilaria Casolaro, Anna Julia Krupa","doi":"10.12740/PP/182933","DOIUrl":"https://doi.org/10.12740/PP/182933","url":null,"abstract":"<p><p>Trazodone is a serotonin antagonist/reuptake inhibitor, approved for treating major depressive disorder (MDD). Oral formulations are widely studied and marketed in several countries worldwide while there is little evidence to support use of parenteral formulation. Our narrative review summarizes pharmacological properties and clinical data concerning use of parenteral trazodone in mood disorders. PubMed and Web of Science were used to identify the most relevant literature. The main evidence concerns four studies evaluating efficacy in major depressive disorder and indicates that trazodone was well tolerated and effective. Off-label use in agitation associated with bipolar disorder is also reported in three studies, although prescription of concomitant treatment, as a confounding factor, may have influenced outcome measures. The limited available evidence supports parenteral trazodone use in major depressive disorder and suggests that trazodone is a suitable option in patients at high risk of treatment-emergent mania (TEM).</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 3","pages":"449-466"},"PeriodicalIF":0.9,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142111395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polish standard of treatment with racemic ketamine for patients with depressive disorders developed by a Working Group appointed by the National Consultant in the field of psychiatry.","authors":"Piotr Gałecki, Katarzyna Maria Bliźniewska-Kowalska, Wiesław Jerzy Cubała, Anna Depukat, Anna Mosiołek, Janusz Rybakowski, Jerzy Samochowiec, Bogusław Sobolewski, Agata Szulc, Dominika Dudek","doi":"10.12740/PP/189494","DOIUrl":"10.12740/PP/189494","url":null,"abstract":"<p><p>The Polish standard of treatment with racemic ketamine for patients with depressive disorders was developed by a Working Group appointed by the National Consultant in the field of psychiatry. Despite the wide range of available medications, as many as one-third of depressed patients do not respond to standard antidepressant treatment, raising the need for an ongoing search for new effective and safe therapies. In recent years, the possible role of overactivity of the glutamatergic system in the etiopathogenesis of depression has again attracted the attention of many experts. The possibility of using substances with a modulating effect on the glutamatergic system in the treatment of depressive disorders has been postulated, among others, the long-known anesthetic ketamine, which is a noncompetitive NMDA receptor antagonist. This paper summarizes the results of studies on the efficacy and safety of racemic ketamine (administered intravenously) in the treatment of patients with depressive symptoms in the course of both unipolar and bipolar affective disorder, and, meeting the expectations of many practicing psychiatrists wishing to broaden the range of therapies offered to their patients, presents recommendations on indications, contraindications, precautions and the treatment regimen itself with intravenous ketamine for patients with mood disorders.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 3","pages":"377-401"},"PeriodicalIF":0.9,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142111397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial.","authors":"Dominika Dudek, Jerzy A Sobański, Katarzyna Klasa","doi":"10.12740/PP/191451","DOIUrl":"https://doi.org/10.12740/PP/191451","url":null,"abstract":"<p><p>no summary.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 3","pages":"373-374"},"PeriodicalIF":0.9,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142111396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polish Adaption of Pregnancy-Related Anxiety Questionnaire - Revised 2 (PRAQ-R2).","authors":"Agata Mikolajkow, Tomasz Fuchs, Krzysztof Małyszczak","doi":"10.12740/PP/OnlineFirst/156324","DOIUrl":"10.12740/PP/OnlineFirst/156324","url":null,"abstract":"<p><strong>Aim: </strong>To create a Polish adaption of the Pregnancy-Related Anxiety Questionnaire - Revised 2 (PRAQ-R2), which is widely used abroad.</p><p><strong>Methods: </strong>PRAQ-R2 was translated into Polish by independent bilingual speakers. Fortyeight pregnant women completed our survey containing the Polish version of PRAQ-R2, Hospital Anxiety and Depression Scale - Modified (HADS-M), and a short sociodemographic questionnaire. After a week, they were asked to complete the PRAQ-R2 questionnaire again. Parametric statistics were used to assess psychometric properties.</p><p><strong>Results: </strong>Our study has shown a good test-retest correlation of 0.70. Participants completed the survey twice (in t1 and after one week - in t2). Cronbach's alpha was calculated as 0.847 at t1 and 0.895 at t2. There was a moderate correlation between PRAQ-R2 at both time points and the HADS-M scale and its subscales.</p><p><strong>Conclusions: </strong>Our Polish adaption of PRAQ-R2 has shown good validity and reliability. It has good internal consistency. Moderate correlation with HADS-M proves that pregnancyrelated anxiety (PrA) is a distinctive disorder from generalized anxiety disorder and depressive disorder. Given the great frequency and the burden of PrA, we believe that PRAQ-R2 should be routinely used among physicians working with pregnant patients.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"519-528"},"PeriodicalIF":0.9,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9917158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Borderlines of psychosis - nosological propositions of Polish psychiatrists of the interwar period.","authors":"Jan Kornaj","doi":"10.12740/PP/171677","DOIUrl":"https://doi.org/10.12740/PP/171677","url":null,"abstract":"<p><p>This paper examines nosological categories relating to borderlines between psychosis and other clinical categories, introduced by Polish psychiatrists in the interwar period. In the United States, the discussion about the borderline between neuroses and psychoses was urged by the 1938 article by psychoanalyst Adolph Stern. In Poland, nosological categories regarding the borderline between neuroses and psychoses were proposed by Adam Wizel, Maurycy Bornsztajn, Jan Nelken, and Władysław Matecki. Wizel coined the term 'underdeveloped schizophrenia', Bornsztajn introduced 'schizothymia reactiva' and 'hypochondriac (somatopsychic) schizophrenia', Nelken described 'mild schizophrenia', first introduced by Moscow psychiatric school of Rosenstein, and Matecki presented the category of neurosis-like (pseudo-neurotic) schizophrenia. Additionally, Julian Dretler, after studying the borderline between schizophrenia and manic-depressive psychosis, coined the term 'mixed psychosis' and expressed conviction that it is an independent nosological entity. Like in the United States, the majority of Polish pioneers of the nosological studies of borderline cases were influenced by psychoanalysis. As a consequence of World War II and the new regime, which forced dialectical materialism and Pavlovism as an official ideology of psychiatry and condemned psychoanalysis, the categories presented in the article became forgotten and have not impacted Polish psychiatric nosology.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 3","pages":"559-569"},"PeriodicalIF":0.9,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142111394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study on the attitude of Polish psychotherapists towards online therapy - Polish adaptation of the UTAUT-T (Unified Theory of Acceptance and Use of Technology - Therapist version) and verification of the UTAUT-T model.","authors":"Agnieszka Koch, Agata Graczykowska, Szymon Szumiał, Magdalena Marszał-Wiśniewska","doi":"10.12740/PP/OnlineFirst/159445","DOIUrl":"10.12740/PP/OnlineFirst/159445","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the study was to verify the psychometric properties of the Polish adaptation of the Unified Theory of Acceptance and Use of Technology - Therapist version (UTAUT-T) and to verify the UTAUT-T model in a group of Polish psychotherapists.</p><p><strong>Methods: </strong>A total of 434 people aged 27-66 (M = 40.78; SD = 7.70), including 337 women and 58 men, took part in an online self-report study, which involved completing three questionnaires: UTAUT-T, the short IPIP-BFM-20 Questionnaire for measuring the Big Five, the Technology Readiness Index (TRI 2.0), as well as answers to questions about the use of digital technologies at work. The following analyses were carried out: confirmatory factor analysis (CFA), reliability analysis using Cronbach's alpha, and theoretical validity analysis - an analysis of the correlation between the subscales of the UTAUT-T instrument and questionnaires enabling the measurement of dimensions which had been indicated in previous research results as related to the acceptance of technology.</p><p><strong>Results: </strong>The conducted analyses showed that the factor structure of the Polish version of UTAUT-T is the same as of the original tool, and the UTAUT-T model was confirmed in the group of Polish psychotherapists. The Cronbach's alpha reliability coefficient for individual subscales ranged from 0.57 to 0.97. The theoretical validity analysis confirmed the expected correlations between most dimensions of technology acceptance and technology readiness. In addition, there were single very weak correlations observed between technology acceptance and personality traits.</p><p><strong>Conclusions: </strong>The psychometric properties of the Polish version of UTAUT-T show satisfactory values. The scale can be used to conduct further research. The UTAUT-T model can be utilized to predict the actual use of new technologies by Polish psychotherapists.</p>","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"541-558"},"PeriodicalIF":0.9,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9917159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}