Psychiatria polska最新文献_第3页

Relational trauma. 关系创伤

IF 0.9 4区医学

Psychiatria polska Pub Date : 2024-06-30 DOI: 10.12740/PP/OnlineFirst/156722

Dorota Draczyńska

引用次数: 0

Management of nicotine dependence in patients with psychiatric disorders - recommendations of the Polish Psychiatric Association - part I. 精神病患者的尼古丁依赖管理--波兰精神病学协会的建议--第一部分。

IF 0.9 4区医学

Psychiatria polska Pub Date : 2024-06-30 DOI: 10.12740/PP/OnlineFirst/161773

Marcin Wojnar, Piotr Wierzbiński, Jerzy Samochowiec, Joanna Rymaszewska, Krzysztof J Filipiak, Adam Wichniak, Robert Mróz, Artur Mamcarz, Dominika Dudek

{"title":"Management of nicotine dependence in patients with psychiatric disorders - recommendations of the Polish Psychiatric Association - part I.","authors":"Marcin Wojnar, Piotr Wierzbiński, Jerzy Samochowiec, Joanna Rymaszewska, Krzysztof J Filipiak, Adam Wichniak, Robert Mróz, Artur Mamcarz, Dominika Dudek","doi":"10.12740/PP/OnlineFirst/161773","DOIUrl":"10.12740/PP/OnlineFirst/161773","url":null,"abstract":"Smoking and nicotine dependence are still one of the main reasons for a number of serious and life-shortening somatic diseases. At the same time, they are more prevalent in mentally ill individuals than in the general population. This work, which constitutes the first part of recommendations of the Polish Psychiatric Association, presents the scale of the phenomenon in the general population and among people with psychiatric disorders, diagnostic criteria of nicotine dependence and nicotine withdrawal. It discusses the impact of smoking and exposure to cigarette smoke on the development and course of psychiatric disorders as well as on the treatment of psychiatric disorders, including interactions between nicotine and psychotropic medications. Many psychiatric patients can reduce smoking or achieve complete abstinence if they are offered adequate motivation and therapeutic support. Contrary to popular belief, smoking cessation and nicotine dependence treatment do not negatively affect the symptoms of psychiatric disorders; patients' mental conditions can improve following smoking cessation therapy. The best results in terms of maintaining abstinence are achieved with a treatment approach that combines pharmacotherapy with psychotherapeutic intervention integrated into routine psychiatric care.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"403-418"},"PeriodicalIF":0.9,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9746116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The evolutionary and neurobiological attributes of consciousness: an update. 意识的进化和神经生物学属性：最新进展。

IF 0.9 4区医学

Psychiatria polska Pub Date : 2024-06-30 DOI: 10.12740/PP/174391

Janusz Rybakowski, Filip Rybakowski

{"title":"The evolutionary and neurobiological attributes of consciousness: an update.","authors":"Janusz Rybakowski, Filip Rybakowski","doi":"10.12740/PP/174391","DOIUrl":"https://doi.org/10.12740/PP/174391","url":null,"abstract":"Consciousness is most frequently defined as a subjective experience of mental processes. The phenomenon of consciousness has always been a subject of great interest in various fields of science, including psychiatry, and the most prominent scientists have engaged in research on it. The studies performed in recent years have brought about novel data on the evolutionary and neurobiological attributes of this phenomenon. In the first part of the article, the evolutionary concepts of consciousness are presented, going back to the beginnings of life on our planet. They are proposed by such illustrious scientists as Joseph LeDoux, Daniel Dennett, António Damásio, and Arthur Reber. Each of them presents the issue of consciousness in the context of evolution slightly differently. However, there are many similarities concerning the development of the nervous system and mental life. The second part discusses the novel research on the cognitive and neurobiological components of consciousness. Among many researchers of this issue, we chose the achievements of two British authors such as Chris Frith and Anil Seth. The neuroanatomical and perceptive aspects of both the level and context of consciousness are provided. Besides presenting the contemporary evolutionary and neurobiological concepts of consciousness, the article aims to bring closer the profiles of the prominent researchers of neuroscience mentioned here. This term can be translated into Polish as \"neuronauka\", although our country's most frequently used name is \"neurobiologia.\"","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 3","pages":"433-448"},"PeriodicalIF":0.9,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142111398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The internment of patients undergoing treatment for alcohol addiction as a result of a specific interpretation of legal provisions by some judicial authorities. 由于某些司法当局对法律规定的特殊解释，正在接受酒精成瘾治疗的病人被拘留。

IF 0.9 4区医学

Psychiatria polska Pub Date : 2024-06-30 DOI: 10.12740/PP/OnlineFirst/155390

Kamila Kocańda, Stanisław Głuszek, Rafał Łoś, Beata Matulińska, Dariusz Zwierzchowski, Agnieszka Zwierzchowska-Łucka

{"title":"The internment of patients undergoing treatment for alcohol addiction as a result of a specific interpretation of legal provisions by some judicial authorities.","authors":"Kamila Kocańda, Stanisław Głuszek, Rafał Łoś, Beata Matulińska, Dariusz Zwierzchowski, Agnieszka Zwierzchowska-Łucka","doi":"10.12740/PP/OnlineFirst/155390","DOIUrl":"10.12740/PP/OnlineFirst/155390","url":null,"abstract":"In the Polish legal system, each medical procedure requires patient's consent. Exemptions from the obligation to obtain such a consent are limited by the legislator to exceptional situations, i.e., when the delay caused by the procedure for obtaining consent would pose a threat to patient's life, serious injury, or serious health impairment. Undergoing addiction treatment is also voluntary. Exceptions to this principle are stipulated by a legal act. People who abuse alcohol and therefore break down family life, demoralize minors, avoid the obligation to meet the needs of their families, or systematically disturb peace or public order, may be obliged to undergo addiction treatment in an inpatient or outpatient treatment centre on condition that they are addicted to alcohol. A patient who fails to report to the medical entity designated by the court to execute the decision on the obligation to undertake addiction treatment may be brought to this entity by the police. In the context of the obligation to obtain a consent for treatment by a person against whom a court decision containing an obligation in this respect has been issued, there are discrepancies in the application of law provisions. In some medical entities, this results in the forced continuation of addiction treatment by a given patient in hospital, as discharge from the hospital depends on a court order issued in this regard, not on the consent of the patient himself/herself. In other medical entities, patients are not admitted for treatment due to the lack of such a consent, despite the court's obligation in this respect. The article confirms that a specific practice of applying the law, which downgrades the role of the patient's consent in the therapeutic process, has negative consequences for the effectiveness of the therapy.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"507-517"},"PeriodicalIF":0.9,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10051297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of nicotine dependence in patients with psychiatric disorders - recommendations of the Polish Psychiatric Association - part II. 精神病患者的尼古丁依赖管理--波兰精神病学协会的建议--第二部分。

IF 0.9 4区医学

Psychiatria polska Pub Date : 2024-06-30 DOI: 10.12740/PP/OnlineFirst/161774

Marcin Wojnar, Piotr Wierzbiński, Jerzy Samochowiec, Joanna Rymaszewska, Krzysztof J Filipiak, Adam Wichniak, Robert Mróz, Artur Mamcarz, Dominika Dudek

{"title":"Management of nicotine dependence in patients with psychiatric disorders - recommendations of the Polish Psychiatric Association - part II.","authors":"Marcin Wojnar, Piotr Wierzbiński, Jerzy Samochowiec, Joanna Rymaszewska, Krzysztof J Filipiak, Adam Wichniak, Robert Mróz, Artur Mamcarz, Dominika Dudek","doi":"10.12740/PP/OnlineFirst/161774","DOIUrl":"10.12740/PP/OnlineFirst/161774","url":null,"abstract":"The development of treatment methods for nicotine dependence has progressed slowly because people with psychiatric disorders are usually excluded from participating in clinical trials. There are several therapeutic options to support smoking cessation, including psychological and pharmacological interventions, which should be offered to smokers with mental disorders. The first step in helping tobacco smokers and nicotine-dependent individuals is the assessment of smoking intensity and confirmation of nicotine dependence. Currently, we have several methods of treating nicotine dependence - starting from education and psychotherapy, through pharmacotherapy and replacement therapy, and ending up with obtaining gradual progress with the application of harm reduction. Pharmacological treatment options include nicotine replacement therapy, varenicline or bupropion. The effectiveness of such interventions can be improved by providing anti-smoking therapy under psychiatric treatment and promoting harm reduction as an acceptable initial therapeutic goal. The harm reduction strategy is an approach that should be taken into account individually, particularly in the case of individuals unable to stop smoking, patients with limited insight into their illness, patients experiencing an exacerbation of their illness and persistently uncooperative patients. In this paper, recommendations of the Polish Psychiatric Association on the diagnostics and different treatment methods for nicotine dependence in patients with psychiatric disorders are presented.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"419-431"},"PeriodicalIF":0.9,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9746117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The rs4354668 polymorphism in the SLC1A2 gene for the EAAT2 glutamate transporter is associated with an increased risk of harmful drug use - an exploratory study on a university student population. EAAT2 谷氨酸转运体 SLC1A2 基因中的 rs4354668 多态性与有害药物使用风险增加有关--一项针对大学生群体的探索性研究。

IF 0.9 4区医学

Psychiatria polska Pub Date : 2024-06-30 DOI: 10.12740/PP/171620

Bartosz Dawidowski, Barbara Olejniczak, Katarzyna Groblińska, Magdalena Knapińska, Urszula Kozicka, Michał Krasiński, Anna Kułak, Grzegorz Grelecki, Zuzanna Czaplińska, Oliwia Piotrowska, Klaudia Kościelecka, Piotr Podwalski, Anna Michalczyk, Jerzy Samochowiec

{"title":"The rs4354668 polymorphism in the SLC1A2 gene for the EAAT2 glutamate transporter is associated with an increased risk of harmful drug use - an exploratory study on a university student population.","authors":"Bartosz Dawidowski, Barbara Olejniczak, Katarzyna Groblińska, Magdalena Knapińska, Urszula Kozicka, Michał Krasiński, Anna Kułak, Grzegorz Grelecki, Zuzanna Czaplińska, Oliwia Piotrowska, Klaudia Kościelecka, Piotr Podwalski, Anna Michalczyk, Jerzy Samochowiec","doi":"10.12740/PP/171620","DOIUrl":"https://doi.org/10.12740/PP/171620","url":null,"abstract":"Objectives: Evidence suggests that decreased dopamine secretion in mesocorticolimbic pathways could predispose to increased susceptibility to substance addiction. It has been proposed to define such a phenomenon as the reward deficit syndrome (RDS). Dopaminergic projections of the reward system receive glutaminergic projections from cortex. Research indicates that a reduction in the stimulating glutamatergic transmission on the dopaminergic system could represent an alternative phenotype of RDS. Potential source of this type of abnormality is glutamate reuptake which depends on excitatory amino acid transport proteins (EAAT) function. The most important of them is EAAT2, polymorphisms of which have been linked to several mental disorders.Methods: We analyzed the genetic and psychometric data of 125 young adults (n = 125) for the effect of the rs4354668 polymorphism of the SLC1A2 gene for EAAT2 on the risky or harmful drug use (RHDU). After exploratory analysis we used logistic regression models to assess the probability of RHDU in individual groups.Results: In the final model T/T variant of rs4354668 was significantly associated with a lower probability of RHDU occurrence compared to G/G variant (OR: 0.021; 95% CI: 0.001 - 0.275; p = 0.009). Other significant predictors of RHDU were smoking status and risky or harmful drinking of alcohol.Conclusions: The results obtained may indicate a possible relationship of the risk of harmful drug use with variants of the rs4354668 polymorphism of the SLC1A2 gene for EAAT2. Subjects with the T/T variant of this polymorphism appear to be less at risk of developing drug use disorders.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 3","pages":"467-494"},"PeriodicalIF":0.9,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142111399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes in temperament, character and intensity of empathy in adolescents treated in a day care unit - pilot study. 在日托所接受治疗的青少年在气质、性格和移情强度方面的变化--试点研究。

IF 0.9 4区医学

Psychiatria polska Pub Date : 2024-05-20 DOI: 10.12740/PP/OnlineFirst/185461

Renata Modrzejewska, Anna Wasik, Paulina Cofór-Pinkowska, Agnieszka Pac, Marcin Siwek

{"title":"Changes in temperament, character and intensity of empathy in adolescents treated in a day care unit - pilot study.","authors":"Renata Modrzejewska, Anna Wasik, Paulina Cofór-Pinkowska, Agnieszka Pac, Marcin Siwek","doi":"10.12740/PP/OnlineFirst/185461","DOIUrl":"https://doi.org/10.12740/PP/OnlineFirst/185461","url":null,"abstract":"Objectives: The aim of this pilot study was to compare the level of empathy, temperament and character traits before and after 6 months of treatment in a group of patients staying in a psychiatric day care unit in groups with different (internalising vs. externalising) disorder types.Methods: The study was conducted in a group of 44 patients (33 girls and 11 boys), aged 15-20, treated between 2016 and 2021 in the Clinical Day Care Unit of the Department of Adult, Child and Adolescent Psychiatry of the University Hospital in Krakow. 40% of the adolescents had externalising disorders and 60% had internalising disorders. The Davis Empathy Scale and the Cohen Empathy Scale were used in the study, as well as the Cloninger' Temperament and Character Inventory (TCI).Results: Six months of treatment in a day care unit resulted in statistically significant changes in the \"Fantasy\" scale from the Davis Empathy Scale, in the \"Reward dependence\", \"Self-directedness\" and \"Self-transcendence\" subscales on the Temperament and Character Inventory in the group of adolescents with internalising disorders. In the group of adolescents with externalising disorders, there were changes at the level of statistical trend in the values of the \"Fantasy\" scale and the \"Harm Avoidance\" scale of the Temperament and Character Inventory.Conclusions: The obtained results are in line with the available data in terms of differences in temperament and character profiles between types of mental disorders and constellations of traits that are unfavourable for mental health, such as low self-directedness, harm avoidance and reward dependence.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"1-15"},"PeriodicalIF":0.9,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effects of mindfulness-based training in virtual reality on psychotic symptoms, mood and cognitive functioning - a pilot study. 虚拟现实中的正念训练对精神病症状、情绪和认知功能的影响--一项试点研究。

IF 0.9 4区医学

Psychiatria polska Pub Date : 2024-04-30 DOI: 10.12740/PP/OnlineFirst/154033

Iga Plencler, Dawid Kruk, Artur Daren, Przemysław Stankiewicz, Agnieszka Nowak, Stanisław Radoń, Adrian Chrobak, Andrzej Cechnicki, Marcin Siwek

{"title":"The effects of mindfulness-based training in virtual reality on psychotic symptoms, mood and cognitive functioning - a pilot study.","authors":"Iga Plencler, Dawid Kruk, Artur Daren, Przemysław Stankiewicz, Agnieszka Nowak, Stanisław Radoń, Adrian Chrobak, Andrzej Cechnicki, Marcin Siwek","doi":"10.12740/PP/OnlineFirst/154033","DOIUrl":"10.12740/PP/OnlineFirst/154033","url":null,"abstract":"Objectives: Virtual reality (VR) is growing in popularity in treating various psychiatric disorders, including psychotic ones. However, no studies have been published on mindfulness interventions aided by virtual reality in psychotic patients to date.Methods: 25 patients with schizophrenia or schizoaffective disorder were assessed at three time points with 4-week intervals using the six-item Positive and Negative Syndrome Scale (PANSS-6), Quick Inventory of Depressive Symptomatology (QIDS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), State-Trait Anxiety Inventory (STAI), Perceived Stress Scale (PSS-10), and the Addenbrooke's Cognitive Examination III (ACE-III). Additionally, the intensity of seven emotions was rated using the Visual Analog Scale (VAS) before and after each training session.Results: The subjects achieved a significant reduction in symptom severity after completing mindfulness training. This was reflected by the PANSS-6 total score, as well as by the subscales for negative and positive symptoms. A significant increase in cognitive functioning (ACE-III scores) was also found. No significant changes in these measures were observed when only the standard intervention was used.Conclusions: Our study indicates good feasibility of the developed mindfulness intervention in VR in schizophrenic patients. The results indicate potential benefits in terms of lessening of the symptoms and improvement in cognition.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"289-302"},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9158483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple-Monitored Electroconvulsive Therapy (MMECT) - does it really just belong in psychiatry's past? A case report. 多重监测电休克疗法（MMECT）--它真的只属于精神病学的过去吗？病例报告。

IF 0.9 4区医学

Psychiatria polska Pub Date : 2024-04-30 DOI: 10.12740/PP/OnlineFirst/156320

Jan Chrobak, Patryk Rodek, Krzysztof Kucia

{"title":"Multiple-Monitored Electroconvulsive Therapy (MMECT) - does it really just belong in psychiatry's past? A case report.","authors":"Jan Chrobak, Patryk Rodek, Krzysztof Kucia","doi":"10.12740/PP/OnlineFirst/156320","DOIUrl":"10.12740/PP/OnlineFirst/156320","url":null,"abstract":"Electroconvulsive therapy has been a method used in psychiatry since 1938 and despite its rather turbulent history, it is still the most effective method of treating severe mental disorders. Despite its high efficiency and good safety profile, patients with catatonia usually require a large number of treatments. It entails a long hospitalization time and the necessity to repeatedly induce general anesthesia. In 1966, Blachly proposed to induce more than one seizure during a single anesthesia. According to this method, the patient was to be constantly monitored (ECG, EEG) during a series of electroconvulsions, which consisted of two to even eight treatments. For simplicity, the method is called multiple-monitored ECT (MMECT). The work is based on the medical history of a patient diagnosed with catatonic schizophrenia. Due to the insufficient effect of single treatments, we decided to use the MMECT method, which was performed in series of three treatments, twice a week. Thanks to the therapy, catatonic symptoms remitted. Studies in various patient populations have shown that MMECT reduces hospitalization time, the duration of acute symptoms, and the patient's total exposure to anesthetics and muscle relaxants. As the above case shows, MMECT can potentially be considered as a safe treatment alternative in patients that require a large number of treatments, resistant to standard forms of therapy.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":" ","pages":"343-349"},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9727881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sixty years of recurrence prevention in mood disorders. 预防情绪障碍复发六十年。

IF 0.9 4区医学

Psychiatria polska Pub Date : 2024-04-30 DOI: 10.12740/PP/169407

Janusz Rybakowski

{"title":"Sixty years of recurrence prevention in mood disorders.","authors":"Janusz Rybakowski","doi":"10.12740/PP/169407","DOIUrl":"10.12740/PP/169407","url":null,"abstract":"This year, we observe sixty's anniversary of the article by a British psychiatrist, Geoffrey Hartigan, demonstrating, for the first time, the possibility of preventing of the recurrence of mood disorders by using lithium salts. Herein, a history of prevention of recurrences of mood disorders both worldwide and in Poland will be presented concerning both lithium and other mood-stabilizing drugs. The merit for verifying the prophylactic lithium effect in the 1960-1970s should be given to Danish researchers, Mogens Schou and Poul Baastrup. In Poland, the first paper on prophylactic lithium appeared already in 1971. In the 1970s, French researchers showed prophylactic activity of valproic acid amide, and Japanese researchers - carbamazepine. In the 1980th, studies on valproic acid amide were performed in the 2nd Psychiatric Clinic of the Institute of Psychiatry and Neurology led by Prof. Pużyński. Since the mid-1990s, 2nd generation of mood-stabilizing drugs has been introduced, including some atypical antipsychotics (clozapine, olanzapine, quetiapine, aripiprazole, risperidone) and anticonvulsant drug, lamotrigine, showing prophylactic activity in bipolar mood disorder. The studies on lithium resulted in the identification of factors connected with its prophylactic efficacy as well as the antisuicidal, antiviral, and neuroprotective effects of this drug. From a sixty-year perspective following Hartigan's article, it seems that his pioneering concept on the possibility of pharmacological influence on the course of mood disorders was fully confirmed. Current Polish recommendations on pharmacological prophylaxis of mood disorders were presented in the books \"Standardy leczenia niektórych zaburzeń psychicznych\" and \"Psychofarmakologia kliniczna\", both published in 2022.","PeriodicalId":20863,"journal":{"name":"Psychiatria polska","volume":"58 2","pages":"223-236"},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0