Radiation Physics and Chemistry最新文献

{"title":"Synchrotron X-ray imaging material from high quantum yield Sm3+- doped Li2O−Gd2O3–ZrO2–P2O5 glass","authors":"K. Payungkulanan ,&nbsp;M. Tungjai ,&nbsp;N. Wantana ,&nbsp;N. Chanthima ,&nbsp;C.S. Sarumaha ,&nbsp;P. Pakawanit ,&nbsp;C. Phoovasawat ,&nbsp;P. Kanjanaboos ,&nbsp;K. Choodam ,&nbsp;H.J. Kim ,&nbsp;S. Kothan ,&nbsp;J. Kaewkhao","doi":"10.1016/j.radphyschem.2025.113072","DOIUrl":"10.1016/j.radphyschem.2025.113072","url":null,"abstract":"<div><div>The fabrication of phosphate glass samples utilized the melt quenching procedure to synthesize the scintillating glass for synchrotron X-ray imaging application.</div><div>A comprehensive investigation of the physical, optical, structural, photoluminescence, radioluminescence properties, and X-ray imaging was conducted. The findings exhibited that the density and refractive index clearly increased with higher concentrations of Sm³⁺ doping.</div><div>The absorption spectra revealed absorbance in the UV–Vis–NIR regions.</div><div>The photoluminescence and radioluminescence spectra exhibited the strongest emission intensities at 0.50 mol% of Sm₂O₃, with a remarkable photoluminescence quantum yield (PLQY) of 85 %. The Sm³⁺ ion revealed its most intense emission peak at 600 nm, relating to the f-f transition (⁴G_5/2 → ⁶H_7/2) of the Sm³⁺ ion. The photoluminescence (PL) emission peak of Gd³⁺ ions at 311 nm exhibited a decreasing trend with the concurrent increase in Sm³⁺ emission intensity. This variation suggests the occurrence of energy transfer from Gd³⁺ to Sm³⁺ ions. The energy transfer was further confirmed by decay time analysis (λ_Ex = 275 nm and λ_Em = 311 nm), which demonstrated a maximum energy transfer efficiency of 66.08 % at a Sm₂O₃ concentration of 2.00 mol%. The decay time (λ_Ex = 401 nm and λ_Em = 600 nm)of Sm³⁺ ion was in the millisecond range, dropping from 3.156 to 0.944 ms when increasing of Sm₂O₃ concentration. The Inokuti-Hirayama (IH) model (S = 6) confirms dipole–dipole interactions as the primary energy transfer mechanism among Sm³⁺ ions. Radioluminescence measurements revealed an integral scintillation efficiency of 55.39 % relative to the standard BGO crystal. High-resolution X-ray imaging using synchrotron radiation demonstrated a spatial resolution of 10 lp/mm and a modulation transfer function (MTF) of 0.46 at this frequency. These findings validate the potential of Sm³⁺-doped phosphate glass as a promising candidate for synchrotron X-ray imaging scintillators.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"237 ","pages":"Article 113072"},"PeriodicalIF":2.8,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144313244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing the gamma radiation shielding performance: The impact of Bi2O3 and MgO nanoparticles on PMMA","authors":"Aml Almutery ,&nbsp;Wan Nordiana Rahman ,&nbsp;Faizal Mohamed ,&nbsp;Chia Chin Hua ,&nbsp;Khairunisak Abdul Razak ,&nbsp;Raizulnasuha Ab Rashid ,&nbsp;U. Rilwan ,&nbsp;M.I. Sayyed ,&nbsp;Yasser Maghrbi","doi":"10.1016/j.radphyschem.2025.113070","DOIUrl":"10.1016/j.radphyschem.2025.113070","url":null,"abstract":"<div><div>This work investigated the gamma radiation shielding performance of different nano-composites (pure PMMA, PMMA doped with Bi₂O₃, PMMA doped with MgO, and PMMA doped with Bi₂O₃–MgO) using the solution casting method. The experimental linear attenuation coefficients (LACs) of the samples were determined using a sodium iodide (NaI) detector and the results were compared with Phy-X theoretical results, where better matching was observed. At 59.5 keV, the PMMA doped with Bi₂O₃ sample had the largest LAC of 0.759 cm⁻¹ when compared to the PMMA doped with Bi₂O₃–MgO sample with a LAC of 0.695 cm⁻¹. At the same energy (59.5 keV), the radiation protection efficiency of the PMMA doped with Bi₂O₃ sample was 31.34 %, which was far greater compared to that of the PMMA doped with Bi₂O₃–MgO sample, thus confirming the PMMA doped with Bi₂O₃ sample as the optimum candidate to be applied for protection against gamma radiation.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"237 ","pages":"Article 113070"},"PeriodicalIF":2.8,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144331107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of asymmetry around Eu3+ ion on luminescence behaviours of ZnO-Na2O-B2O3 glasses synthesized by microwave and conventional melting methods: Red emitting material application","authors":"N. Singkiburin, N. Srisittipokakun, N. Kiwsakunkran, R. Rajaramakrishna, C.S. Sarumaha, W. Busayaporn, A. Angnanon, N. Intachai, S. Kothan, H.J. Kim, J. Kaewkhao","doi":"10.1016/j.radphyschem.2025.113082","DOIUrl":"https://doi.org/10.1016/j.radphyschem.2025.113082","url":null,"abstract":"The new comparison techniques using the microwave-assisted (MW) and conventional melt-quench (EF) were studied on Eu<ce:sup loc=\"post\">3+</ce:sup>-doped B<ce:inf loc=\"post\">2</ce:inf>O<ce:inf loc=\"post\">3</ce:inf>-ZnO-Na<ce:inf loc=\"post\">2</ce:inf>O glasses. The optical and structural properties were examined to understand the effect of Eu<ce:sup loc=\"post\">3+</ce:sup> local environment on luminescence properties. The XRD pattern exhibits characteristic signature of an amorphous structure. The dominant emission peak at 614 nm (<ce:sup loc=\"pre\">5</ce:sup>D<ce:inf loc=\"post\">0</ce:inf> → <ce:sup loc=\"pre\">7</ce:sup>F<ce:inf loc=\"post\">2</ce:inf> transition) under excitation at 395 nm shows a greater intensity with the MW_Eu technique. These results are supported by analyses using EXAFS and JO parameters to confirm the asymmetrical structure. The higher Debye-Waller factor (σ<ce:sup loc=\"post\">2</ce:sup>) and Judd-Ofelt parameter (Ω<ce:inf loc=\"post\">2</ce:inf>) show in MW_Eu than EF_Eu techniques. The MW_Eu glass also displayed a higher ED/MD ratio (R = 3.2667), confirming stronger Eu-O covalent bonding. Radioluminescence measurements showed that MW_Eu had a scintillation efficiency of 58%, outperforming EF_Eu (48%) relative to BGO standards. CIE chromaticity analysis confirmed red emission from the glasses, with MW_Eu exhibiting coordinates of (x = 0.61, y = 0.38) and a low correlated color temperature (CCT) of 1660 K, indicating its suitability for red light-emitting applications. Combined results from the CIE diagram and X-ray imaging further demonstrated that the MW technique is more favorable than the EF method for use in red-emitting photonic and X-ray imaging applications.","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"29 1","pages":"113082"},"PeriodicalIF":2.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sugarcane bagasse-derived activated Carbon/LiFePO4 composite nanostructures for lithium-ion battery applications","authors":"Sukanya Nilmoung ,&nbsp;Wanwisa Limphirat ,&nbsp;Sompin Mahakot ,&nbsp;Artit Ausavasukhi","doi":"10.1016/j.radphyschem.2025.113084","DOIUrl":"10.1016/j.radphyschem.2025.113084","url":null,"abstract":"<div><div>A composite nanostructure of sugarcane bagasse-derived activated carbon/lithium iron phosphate (SBAC/LiFePO₄) was fabricated using the sol-gel method for potential application in lithium-ion batteries. Sugarcane bagasse (SB) was selected as the raw material for activated carbon to mitigate environmental pollution caused by its burning, a practice facing growing public opposition. All prepared samples showed an orthorhombic structure with a Fe²⁺ oxidation state. The sample carbonized at 800 °C showed a maximum specific capacity of 123 mAh·g⁻¹ (∼72 % of the theoretical specific capacity) with a capacity retention of 80 %. The lowest capacity loss (20 %) after 100 cycles indicates its excellent cycling stability. The superior electrochemical performance is attributed to its high crystallinity percentage, larger particle and crystalline sizes, lower I_D/I_G, and increased surface area. The high electrochemical performance and low cost of this composite material suggest its suitability for use in lithium-ion batteries.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"237 ","pages":"Article 113084"},"PeriodicalIF":2.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ISO 4037 Narrow spectrum X-ray reference field","authors":"Ngoc-Thiem Le ,&nbsp;Thanh-Phi-Hung Hoang ,&nbsp;Ngoc-Quynh Nguyen ,&nbsp;Duc-Ky Bui ,&nbsp;Van-Loat Bui ,&nbsp;Tien-Hung Dinh ,&nbsp;Van-Hoang Dao ,&nbsp;Hoang-Long Nguyen ,&nbsp;Huu-Loi Le ,&nbsp;Charles Debuiche ,&nbsp;Nguyen Ngoc Anh ,&nbsp;Hoai-Nam Tran","doi":"10.1016/j.radphyschem.2025.113002","DOIUrl":"10.1016/j.radphyschem.2025.113002","url":null,"abstract":"<div><div>Characterization of the ISO-4037 narrow spectrum (N-series, “series” stands for the maximum spectral energy in keV) X-ray reference field has been performed. In details, radiometric (i.e., mean energy, spectral resolution, half-value layer, beam homogeneity coefficient) and physical (air Kerma rate) parameters have been investigated for different N-series X-ray beam qualities (i.e., N-40, N-60, N-80, N-100, N-120, and N-150) using either simulation-based and theoretical calculations or experimental measurements. In addition, the dosimetric conversion coefficients from air kerma to ambient dose equivalent and to personal dose equivalent at the normal incident angle have been deduced, and the combined standard uncertainties of investigated quantities were evaluated or estimated, whenever possible. The simulated and experimental data obtained from this work demonstrated good agreement and were consistent with reference data published in the ISO-4037 series and with those reported by the German primary standard dosimetry laboratory, indicating the reliability of the present findings. A comparison with data from other international standard dosimetry laboratories revealed a few anomalous values. It is recommended that these discrepancies should be further investigated and re-evaluated to ensure the consistency and accuracy of related calibration procedures.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"237 ","pages":"Article 113002"},"PeriodicalIF":2.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Patient Radiation Exposure during Common Digital Radiography Procedures in a Saudi Tertiary Hospital","authors":"Yousif Abdallah, Abdullah Alamoudi","doi":"10.1016/j.radphyschem.2025.113085","DOIUrl":"https://doi.org/10.1016/j.radphyschem.2025.113085","url":null,"abstract":"This study was conducted on patients undergoing diagnostic X-ray examinations at King Khalid Hospital (KKH) in Majmaah. The investigation focused on the seven most commonly performed radiographic procedures, encompassing a total of 1,504 patients examined using digital radiography (DR) equipment. Patient radiation doses were assessed by calculating the Entrance Surface Air Kerma (ESAK) and Effective Dose (ED), using measured X-ray tube output and exposure parameters. Based on these measurements, appropriate conversion coefficients were applied. This study also analyzed the 75th percentile distributions of ESAK and Kerma Area Product (KAP) and compared the findings with national and international dose reference levels. This study presents the calculated uncertainty (U) values along with the mean ESAK, KAP, and ED values. The recorded ESAK values ranged from 0.12 to 5.74 mGy, KAP from 0.9 to 1.84 Gy·cm<ce:sup loc=\"post\">2</ce:sup>, and ED from 0.01 to 0.23 mSv. These values were found to be significantly lower than the Diagnostic Reference Levels (DRLs) reported in European and national studies, indicating a positive trend in dose optimization. This study emphasizes the importance of regular dose audits and patient dose awareness. Educating patients on radiation risks and optimizing radiographic techniques are essential for minimizing unnecessary exposure while maintaining high diagnostic image quality.","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"22 1","pages":"113085"},"PeriodicalIF":2.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiation-induced degradation of sulfonamides (SAs) antibiotics by gamma radiation: Effect of ferrous ion","authors":"Yuankun Liu ,&nbsp;Yuening Song ,&nbsp;Jianlong Wang","doi":"10.1016/j.radphyschem.2025.113076","DOIUrl":"10.1016/j.radphyschem.2025.113076","url":null,"abstract":"<div><div>In this study, the radiation-induced degradation of two sulfonamides (SAs): sulfadiazine (SD) and sulfamethazine (SMT), was investigated, focusing on the synergistic effect of ferrous ion (Fe²⁺). The initial concentration of SD and SMT solutions were 20 mg/L, which were irradiated in the presence of 0.4 mM Fe²⁺. The results showed that gamma radiation was effective in SAs degradation and the degradation reaction conformed to the pseudo first-order kinetics. However, the removal of TOC (Total Organic Carbon) and TN (Total Nitrogen) were not as effective as that of SAs degradation. TOC removal efficiency was less than 10 % at 1.0 kGy, while 80 % of SD and 90 % of SMT were removed. Sulfate (SO₄²⁻) and two small molecules of organic acids were detected. The possible pathways of SD and SMT degradation were investigated by density functional theory (DFT) and the analysis of intermediate products. The biodegradability of SAs-containing solution could be enhanced obviously by gamma radiation. More importantly, the comprehensive toxicity of the final intermediates was lower than that of SAs, based on the quantitative structure-activity relationship (QSAR) prediction.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"237 ","pages":"Article 113076"},"PeriodicalIF":2.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive examination of synthesis, microstructure, and radiation shielding effectiveness of multi-layered polymeric GNP-nanocomposites","authors":"Abdelmoneim Saleh ,&nbsp;Anastasiia Kobyliukh ,&nbsp;N.M. Basfer ,&nbsp;S.M. Tajudin ,&nbsp;Urszula Szeluga","doi":"10.1016/j.radphyschem.2025.113078","DOIUrl":"10.1016/j.radphyschem.2025.113078","url":null,"abstract":"<div><div>In the current study, a hybrid structures based on graphene nano-platelets (GNP) decorated with iron oxide (I_op) prepared in ambient atmosphere have been synthesized at different content of I_op (5 %, 10 %, 15 %, and 20 %). The manufacturing of nano-composites films were successfully proven by XRD patterns, SEM and Raman spectra. Four GNP/Fe₃O₄ (GNP/IO N₂) nano-composites were evaluated for their gamma-ray shielding capabilities using gamma spectrometry experimental technique. Various shielding parameters of γ-rays, including linear attenuation coefficient (μ), mass attenuation coefficient (μ_m), half-value layer (HVL), effective atomic number (Z_eff), electron density (N_el), mean free path (λ), and radiation protection effectiveness, were measured experimentally at 11 energy lines from 0.244 to 1.408 MeV using NaI (Tl) scintillator detector and a variety of radioisotopes, such as Cs-137, Eu-152, and Co-60. The mass attenuation coefficients at various energies increased dramatically as the filler weight percentage increased. The S4 sample's greatest effective atomic number (Z_eff) values range from 11.631 to 13.564, while its minimum half-value layer (HVL) values range from 1.895 to 8.985 cm. Additionally, the S4 sample had the highest protection against photons out of all the examined samples, providing 100 % protection against X-ray photons up to 50 keV. It is an effective material for applications involving X-ray shielding. The created samples are lightweight, flexible, and reasonably priced, and they might be employed as a non-toxic nano-filler instead of traditional lead, which is dangerous and dense.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"237 ","pages":"Article 113078"},"PeriodicalIF":2.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144280772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A structural study of MoSe2 nanoflakes prepared via liquid phase exfoliation: X ray absorption and photoemission study","authors":"Yuttakarn Rattanachai ,&nbsp;Panwad Chavalekvirat ,&nbsp;Kamolwan Rintramee ,&nbsp;Narasak Pandech ,&nbsp;Rakchat Klinkla ,&nbsp;Jintara Padchasri ,&nbsp;Sumeth Siriroj ,&nbsp;Ratchadaporn Supruangnet ,&nbsp;Wutthikrai Busayaporn ,&nbsp;Pinit Kidkhunthod ,&nbsp;Prayoon Songsiriritthigul ,&nbsp;Denis Céolin ,&nbsp;Pawin Iamprasertkun ,&nbsp;Thanit Saisopa","doi":"10.1016/j.radphyschem.2025.113083","DOIUrl":"10.1016/j.radphyschem.2025.113083","url":null,"abstract":"<div><div>Two-dimensional materials, particularly transition metal dichalcogenides (TMDs), have garnered significant interest due to their tunable structural and chemical properties when exfoliated to lower dimensions. Exfoliated TMDs have been widely applied across various fields that support the United Nations Sustainable Development Goals (UN-SDGs), especially SDG 7 (Affordable and Clean Energy) and SDG 13 (Climate Action), through their use in energy storage, electrocatalysis, and water treatment membranes. Among TMDs, molybdenum diselenide (MoSe₂) has received comparatively less attention; however, it exhibits outstanding properties similar to those of MoS₂. This study proposes a greener synthesis route for MoSe₂ via liquid-phase exfoliation using an alcohol-based solvent mixture a scalable and cost-effective alternative to conventional methods. Unlike traditional approaches that rely on toxic solvents such as N-methyl-2-pyrrolidone (NMP), our method employs a more environmentally friendly ethanol-water mixture. This eco-conscious process reduces environmental impact while preserving material quality. Comprehensive characterization techniques, including X-ray Absorption Spectroscopy (XAS) and X-ray Photoelectron Spectroscopy (XPS), were employed to investigate the crystallinity, morphology, and composition of the exfoliated MoSe₂. The results highlight the importance of sustainable solvent systems in optimizing exfoliation efficiency and advancing green chemistry principles. By integrating environmentally responsible synthesis with in-depth material analysis, this work contributes to the sustainable development of 2D material production.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"237 ","pages":"Article 113083"},"PeriodicalIF":2.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extravasation Modeling from a CT/PET Imaging for a Possible Digital Twin Approach","authors":"Lorenzo Isolan, Nicola Panico, Federica Fioroni, Elisa Grassi, Mauro Iori, Marco Sumini","doi":"10.1016/j.radphyschem.2025.113080","DOIUrl":"https://doi.org/10.1016/j.radphyschem.2025.113080","url":null,"abstract":"Extravasation of radiopharmaceuticals during PET procedures can compromise both diagnostic accuracy and patient safety by altering tracer pharmacokinetics and delivering unintended local radiation doses. A clinically observed 18F-FDG extravasation case has been reconstructed through a superposition of co-recorded CT and PET DICOM scan images to localize and quantify the extravasated activity. Building on advances in personalized computational modeling, the Digital Twin paradigm could offer a powerful framework for patient-specific dosimetry. Anatomical segmentation has been performed using Synopsys® Simpleware™ Medical to generate an accurate 3D model of the injection site and surrounding tissues. This Digital Twin has been completed through the build-up of an Unstructured Mesh domain that can be studied with the MCNP6© Monte Carlo code for particle transport simulations, incorporating the effective half-life of 18F-FDG to reflect dynamic radiotracer clearance. The digital twin has been benchmarked through OLINDA/EXM® code and thanks to dose-rate measurement performed with the Thermo Fisher Scientific Inc.© RadEye SPRD detector directly on the oncological injected patient. By embodying a patient’s anatomy, physiology, and radiotracer kinetics in a digital twin, this methodology provides a robust tool for personalized dosimetry of extravasation events. The framework is readily extensible to other radiopharmaceuticals and therapeutic contexts, supporting safer and more effective nuclear medicine practices.","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"65 1","pages":"113080"},"PeriodicalIF":2.9,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}