Radiologia Brasileira最新文献

{"title":"Experience in other segments should shorten studies using Look-Locker and high-resolution T2 images in the study of focal lung lesions.","authors":"Marcelo Souto Nacif","doi":"10.1590/0100-3984.2024.57.e8-en","DOIUrl":"https://doi.org/10.1590/0100-3984.2024.57.e8-en","url":null,"abstract":"","PeriodicalId":20842,"journal":{"name":"Radiologia Brasileira","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11494724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142506758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Look-Locker T1 relaxometry and high-resolution T2 in the evaluation of lung lesions: a single-center prospective study.","authors":"Danilo Tadao Wada, Li Siyuan Wada, Camila Vilas Boas Machado, Mateus Repolês Lourenço, Tales Rubens de Nadai, Federico Enrique Garcia Cipriano, Alexandre Todorovic Fabro, Marcel Koenigkam-Santos","doi":"10.1590/0100-3984.2024.0033","DOIUrl":"https://doi.org/10.1590/0100-3984.2024.0033","url":null,"abstract":"<p><strong>Objective: </strong>To explore the feasibility of two magnetic resonance imaging (MRI) sequences-high-resolution T2-weighted (HR T2) and Look-Locker T1 (LL T1) relaxometry-for the investigation focal lung lesions (FLLs). As a secondary objective, we analyzed the diagnostic accuracy of these sequences.</p><p><strong>Materials and methods: </strong>This was a prospective observational study involving 39 subjects with FLLs scanned in a 1.5-T MRI system with LL T1 relaxometry and HR T2 sequences focused on the FLL region, in addition to a conventional protocol. All images were evaluated by two radiologists, working independently, who were blinded to other findings.</p><p><strong>Results: </strong>Most of the examinations (31 of the LL T1 relaxometry sequences and 36 of the HR T2 sequences) were of adequate diagnostic quality. Nondiagnostic examinations were considered so mainly because of limited coverage of the sequences. Of the FLLs studied, 19 were malignant, 17 were benign, and three were excluded from the accuracy analysis because there was no definitive diagnosis. Although LL T1 relaxometry could not distinguish between benign and malignant lesions, the signal intensity at its first inversion time (160 ms) differed between the two groups. The HR T2 sequence was considered the best sequence for assessing specific morphological characteristics, especially pseudocavities and pleural tags. We found that MRI showed better accuracy than did computed tomography (86% vs. 74%).</p><p><strong>Conclusion: </strong>Both MRI sequences are feasible for the evaluation of FLLs. Images at 160 ms of the LL T1 relaxometry sequence helped distinguish between benign and malignant lesions, and the HR T2 sequence was considered the best sequence for evaluating specific morphological characteristics.</p>","PeriodicalId":20842,"journal":{"name":"Radiologia Brasileira","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11469640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rectal cancer management: the essential role of magnetic resonance imaging in neoadjuvant therapy.","authors":"Aley Talans, Giuseppe D'Ippolito","doi":"10.1590/0100-3984.2024.57.e6","DOIUrl":"10.1590/0100-3984.2024.57.e6","url":null,"abstract":"","PeriodicalId":20842,"journal":{"name":"Radiologia Brasileira","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The importance of PSMA PET/CT in evaluating biochemical recurrence in patients with prostate cancer and the need to expand access to this examination via public health care systems.","authors":"Ronaldo Hueb Baroni","doi":"10.1590/0100-3984.2024.57.e5-en","DOIUrl":"10.1590/0100-3984.2024.57.e5-en","url":null,"abstract":"","PeriodicalId":20842,"journal":{"name":"Radiologia Brasileira","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of glial tumors: correlation between magnetic resonance imaging and histopathological analysis.","authors":"Lillian Gonçalves Campos, Francine Hehn de Oliveira, Ápio Cláudio Martins Antunes, Juliana Ávila Duarte","doi":"10.1590/0100-3984.2024.0025","DOIUrl":"https://doi.org/10.1590/0100-3984.2024.0025","url":null,"abstract":"<p><strong>Objective: </strong>To determine the correlation of conventional and diffusion-weighted imaging findings on magnetic resonance imaging (MRI) of the brain, based on Visually AcceSAble Rembrandt Images (VASARI) criteria, with the histopathological grading of gliomas: low-grade or high-grade.</p><p><strong>Materials and methods: </strong>Preoperative MRI scans of 178 patients with brain gliomas and pathological confirmation were rated by two neuroradiologists for tumor size, location, and tumor morphology, using a standardized imaging feature set based on the VASARI criteria.</p><p><strong>Results: </strong>In the univariate analysis, more than half of the MRI characteristics evaluated showed a significant association with the tumor grade. The characteristics most significantly associated with the tumor grade were hemorrhage; restricted diffusion; pial invasion; enhancement; and a non-contrast-enhancing tumor crossing the midline. In a multivariable regression model, the presence of enhancement and hemorrhage maintained a significant association with high tumor grade. The absence of contrast enhancement and restricted diffusion were associated with the presence of an isocitrate dehydrogenase gene mutation.</p><p><strong>Conclusion: </strong>Our data illustrate that VASARI MRI features, especially intratumoral hemorrhage, contrast enhancement, and multicentricity, correlate strongly with glial tumor grade.</p>","PeriodicalId":20842,"journal":{"name":"Radiologia Brasileira","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11406976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"U-SMAS: ultrasound findings of the superficial musculoaponeurotic system.","authors":"Luciana C Zattar, Gladstone Faria, Ricardo Boggio","doi":"10.1590/0100-3984.2024.0035","DOIUrl":"https://doi.org/10.1590/0100-3984.2024.0035","url":null,"abstract":"<p><p>The superficial musculoaponeurotic system (SMAS) is a complex fibrous network connecting facial muscles to the dermis, with varying morphological characteristics across different facial regions. Recent studies have identified five distinct types of SMAS morphology, highlighting the need for region-specific interventions in facial rejuvenation. This pictorial essay explores ultrasound imaging of the SMAS using ultra-high frequency (24-33 MHz) probes, known as U-SMAS. Analysis of 186 full-face U-SMAS scans revealed consistent patterns in the facial and neck layers, with regional variations aligning with the Sandulescu classifications: type I (preparotideal); type II (chin and lip); type III (eyelid); type IV (temporal and parotideal); and type V (cervical). Understanding these morphological differences is crucial for accurate interpretation of ultrasound images and for optimizing pre-procedural assessments to ensure that aesthetic treatments are safe and effective. Knowledge of the SMAS architecture enhances the ability to visualize facial and neck anatomy accurately, particularly through U-SMAS imaging, ensuring comprehensive patient care in rejuvenation procedures.</p>","PeriodicalId":20842,"journal":{"name":"Radiologia Brasileira","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PSMA PET/CT in the Brazilian Unified Healthcare System reduces costs with futile salvage therapies in the management of cases of biochemical recurrence of prostate cancer.","authors":"Mateos Bogoni, Juliano Julio Cerci, Evelinda Marramon Trindade, Miguel Morita Fernandes da Silva, Marina Bicalho Silveira, Jônatas Luiz Pereira, Murilo de Almeida Luz, Bernardo Corrêa de Almeida Teixeira","doi":"10.1590/0100-3984.2024.0024","DOIUrl":"https://doi.org/10.1590/0100-3984.2024.0024","url":null,"abstract":"<p><strong>Objective: </strong>To compare costs between treatment strategies employed prior to and after prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) via the Brazilian Unified Health Care System and their impact on the therapeutic management of biochemical recurrence of prostate cancer.</p><p><strong>Materials and methods: </strong>The referring physicians were surveyed on their treatment intentions (strategies) at two different time points: prior to and after PSMA PET/CT. Cost comparison results are presented as median (IQR) for each of the two strategies. The shift in therapeutic management after PSMA PET/CT was also analyzed.</p><p><strong>Results: </strong>The study sample included 59 patients (mean age: 65.9 years). The PSMA PET/CT result was considered positive in 38 patients (64.4%) and was found to have an impact on the treatment strategy in for 36 patients (61.0%). Prior to PSMA PET/CT, salvage therapy (i.e., treatment with curative intent) was the intended treatment for most patients, and that was significantly less so after the examination (76.3% vs. 45.8%; <i>p</i> < 0.001). Conversely, a strategy involving systemic (i.e., palliative) therapy became more common after PSMA PET/CT (23.7% vs. 54.2%; <i>p</i> < 0.001). The after-PSMA PET/CT strategy presented higher overall costs than did the before-PSMA PET/CT strategy, in all scenarios evaluated. In all scenarios, nearly half of this cost difference was related to the cost of the PSMA PET/CT itself, the remainder being related to the new treatment choices that stemmed from knowledge of the PSMA PET/CT findings.</p><p><strong>Conclusion: </strong>For patients treated within the Brazilian Unified Health Care System, PSMA PET/CT presented higher costs in comparison with conventional imaging methods. Adding PSMA PET/CT to the workflow had an impact on therapeutic management, mainly representing a shift from futile curative treatments to systemic palliative ones. The amount of funds that could potentially be saved by not providing such futile treatments would suffice to evaluate roughly two patients with PSMA PET/CT scans for each futile treatment strategy avoided.</p>","PeriodicalId":20842,"journal":{"name":"Radiologia Brasileira","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metastases to inguinal lymph nodes in prostate cancer: a new perspective on an uncommon pattern of spread.","authors":"Alice Schuch","doi":"10.1590/0100-3984.2024.57.e4-en","DOIUrl":"https://doi.org/10.1590/0100-3984.2024.57.e4-en","url":null,"abstract":"","PeriodicalId":20842,"journal":{"name":"Radiologia Brasileira","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The additional benefit of computed tomography in cancer patients: impacts of sarcopenia and cachexia on quality of life during chemotherapy.","authors":"Galtieri Otávio Cunha de Medeiros, Ilanna Marques Gomes da Rocha, Aline Marcadenti, Ricardo Andrade Bezerra, Erica Roberta Barbalho, Carlos Alves de Sousa Júnior, Ana Paula Trussardi Fayh","doi":"10.1590/0100-3984.2024.0012","DOIUrl":"https://doi.org/10.1590/0100-3984.2024.0012","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluates the effects of sarcopenia and cachexia on the quality of life (QoL) of patients with gastrointestinal cancer during their initial cycle of chemotherapy, emphasizing the significance of computed tomography (CT) in assessing muscle mass.</p><p><strong>Materials and methods: </strong>In this prospective study, we evaluated 60 adult patients with gastrointestinal cancer who started chemotherapy between January and December of 2017. Sarcopenia was diagnosed on the basis of CT findings, and QoL was assessed with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30.</p><p><strong>Results: </strong>The mean age was 60.9 years, and 33 (55.0%) of the patients were men. Of the 60 patients, 33 (55.0%) had cachexia and 14 (23.3%) had sarcopenia. Chemotherapy significantly reduced QoL, particularly in the physical, role functioning, and social domains, with no differences between the cachexia and sarcopenia groups.</p><p><strong>Conclusion: </strong>Among patients with gastrointestinal cancer submitted to chemotherapy, the chemotherapy-induced decline in QoL does not seem to differ significantly between those with cachexia or sarcopenia, as classified by CT-measured muscle mass, and those without. However, CT-based muscle mass evaluation remains crucial for guiding customized intervention strategies. Integrating this evaluation in radiological reports can provide valuable insights for planning specific care, thus improving patient QoL during treatment.</p>","PeriodicalId":20842,"journal":{"name":"Radiologia Brasileira","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parkinson's disease and levodopa-induced dyskinesias: a quantitative analysis through ^99mTc-TRODAT-1 SPECT imaging of the brain.","authors":"Felipe Arriva Pitella, Leonardo Alexandre-Santos, Kleython José Coriolano Cavalcanti de Lacerda, Ana Carolina Trevisan, Mery Kato, Fernando Eduardo Padovan-Neto, Vitor Tumas, Lauro Wichert-Ana","doi":"10.1590/0100-3984.2023.0082","DOIUrl":"10.1590/0100-3984.2023.0082","url":null,"abstract":"<p><strong>Objective: </strong>To compare the dopamine transporter (DAT) density with other risk factors for L-DOPA-induced dyskinesia (LID) in patients with Parkinson's disease (PD), with and without LID.</p><p><strong>Materials and methods: </strong>We evaluated 67 subjects: 44 patients with idiopathic PD of varying degrees of severity (PD group), and 23 healthy age-matched volunteers (control group). Among the 44 patients in the PD group, 29 were male and the following means were recorded at baseline: age, 59 ± 7 years; disease duration, 10 ± 6 years; Hoehn and Yahr (H&Y) stage, 2.16 ± 0.65; and Unified Parkinson's Disease Rating Scale part III (UPDRS III) score, 29.74 ± 17.79. All subjects underwent ^99mTc-TRODAT-1 SPECT. We also calculated specific uptake ratios or binding potentials in the striatum.</p><p><strong>Results: </strong>The DAT density in the ipsilateral and contralateral striata was lower in the PD group. The variables disease duration, L-DOPA dosage, doses per day, L-DOPA effect duration time, H&Y stage, and UPDRS III score explained the occurrence of LID. The DAT density in the ipsilateral striatum, contralateral striatum, and caudate nucleus was lower in the patients with LID than in those without.</p><p><strong>Conclusion: </strong>Our findings suggest that presynaptic dopaminergic denervation is associated with LID in individuals with PD.</p>","PeriodicalId":20842,"journal":{"name":"Radiologia Brasileira","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}