{"title":"Establishment of acquired radioresistant cells to fractionated radiation from hTERT-immortalized normal human epithelial cell.","authors":"Masatoshi Suzuki, Rio Isobe, Taku Sato, Ryoya Ishikawa, Keiji Suzuki, Yasushi Kino, Tomisato Miura, Yohei Inaba, Koichi Chida, Manabu Fukumoto","doi":"10.1093/rpd/ncae118","DOIUrl":"https://doi.org/10.1093/rpd/ncae118","url":null,"abstract":"<p><p>Senescence-like growth arrest (SLGA), which is a radiation-induced cell death pathway, is induced in immortalized normal human epithelial cell (hTERT-RPE1) by the daily fractionated X-irradiation with 1.5 Gy within 30 times. We here demonstrate that pre-treatment induces acquired radioresistance (ARR) that can survive from the lethal fractionated radiation. The parent cells were daily fractionated with 1.5 Gy for 5 d and then incubated for 7 d without fractionated radiation. After this, the daily fractionated radiation with 1.5 Gy was restarted. A small population of surviving cells appeared after 30 times of the daily fractionated radiation was completed and they were continuously growing up to 120 times of the daily fractionated radiation (RPE1-1.5Fr). We confirmed a higher basal expression level of p53, which functions in the activation of the SLGA pathway but fails to further accumulate after 1.5 Gy of single irradiation in RPE1-1.5Fr. It is the first report to induce ARR phenotype for fractionated radiation in normal human cells.</p>","PeriodicalId":20795,"journal":{"name":"Radiation protection dosimetry","volume":"200 16-18","pages":"1636-1640"},"PeriodicalIF":0.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miklós Hegedűs, Haruka Kuwata, Khemruthai Kheamsiri, Maté Novák, Ryohei Yamada, Naofumi Akata, Tibor Kovács
{"title":"Tritium determination in natural water samples in Fukushima from 2022 to 2023 using an ultra-low-level tritium counting system.","authors":"Miklós Hegedűs, Haruka Kuwata, Khemruthai Kheamsiri, Maté Novák, Ryohei Yamada, Naofumi Akata, Tibor Kovács","doi":"10.1093/rpd/ncae166","DOIUrl":"https://doi.org/10.1093/rpd/ncae166","url":null,"abstract":"<p><p>The Fukushima Daiichi Nuclear Power Plant (FDNPP) accident created large stockpiles of tritium containing cooling water, which is to be gradually released into the Pacific Ocean, gaining attention from surrounding countries, environmental groups, and local residents concerned with the possibility of increasing tritium concentrations in the water and food cycle. Establishing baseline concentration levels and monitoring tritium immission values are important for assuring public safety, providing data for scientific research and risk communication. Tritium concentrations in the environment are very low; therefore, tritium measurements require enrichment in order to estimate the radiation exposure from drinking water intake and provide information on the water cycle. Natural water samples were collected at Tomioka Town located south of the FDNPP. Samples were distilled, enriched by electrolysis, and re-distilled using an improved SPE method to preconcentrate tritium to measureable levels. Tritium concentrations were determined by a low-background liquid scintillation counter. The observed tritium concentrations were relatively low, rainwater had a mean and SD value of 0.40 ± 0.13 Bq/L, and freshwater samples showed similar concentrations, while brackish coastal water samples were below 0.13 ± 0.02 Bq/L. The observed tritium concentrations in this study are considered safe as effective doses based on annual drinking water intake; however, continous monitoring is necessary to assure public safety.</p>","PeriodicalId":20795,"journal":{"name":"Radiation protection dosimetry","volume":"200 16-18","pages":"1845-1849"},"PeriodicalIF":0.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minseok Kim, Toshihiro Shibata, Takayuki Sasaki, Junichi Suzuki
{"title":"ICP-MS determination of background I-129 in seaweed samples around Fukushima Daiichi NPS.","authors":"Minseok Kim, Toshihiro Shibata, Takayuki Sasaki, Junichi Suzuki","doi":"10.1093/rpd/ncae163","DOIUrl":"https://doi.org/10.1093/rpd/ncae163","url":null,"abstract":"<p><p>TEPCO planned the release of Advanced Liquid Processing System (ALPS)-treated water, which is decontaminated stagnated water by ALPS, to the Pacific Ocean in 2023 after diluting it more than a hundred times in accordance with the policy of the Japan government. Since the low level of I-129 can remain in ALPS-treated water, the background I-129 concentration in seaweed samples around 1F NPS before the release of ALPS-treated water was recorded in this study. The iodine in seaweed samples was extracted via TMAH alkali-dissolution, and the I-129 concentration was measured by 8900 Triple Quadrupole ICP-MS. The resulting I-129 concentration was <5.4 × 10-2 Bq/kg-wet (sargassum) and <2.7 × 10-2 Bq/kg-wet (laminaria), respectively.</p>","PeriodicalId":20795,"journal":{"name":"Radiation protection dosimetry","volume":"200 16-18","pages":"1850-1855"},"PeriodicalIF":0.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Attempt to re-estimate organ doses of victims in non-homogeneous exposure accident by means of the state-of-the-art Mesh-type Reference Computational Phantom-a case study of an IR-192 source accident.","authors":"Munehiko Kowatari, Hiroshi Yoshitomi, Kotaro Tani, Yoshihiko Tanimura, Osamu Kurihara","doi":"10.1093/rpd/ncae070","DOIUrl":"https://doi.org/10.1093/rpd/ncae070","url":null,"abstract":"<p><p>An attempt was made to estimate organ doses of a victim in a high-dose non-homogeneous exposure accident caused by a sealed 192Ir gamma-ray source. The Gilan accident was selected as a case study. Organ doses including testis, red bone marrow and so on were properly estimated by applying the Monte Carlo calculation with the state-of-the-art adult male Mesh type Reference Computational Phantom. By introducing a complicated exposure scenario, the dose distribution on the right chest of the victim in the Gilan accident could be reproduced to a certain extent.</p>","PeriodicalId":20795,"journal":{"name":"Radiation protection dosimetry","volume":"200 16-18","pages":"1574-1579"},"PeriodicalIF":0.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Krzysztof W Fornalski, Łukasz Adamowski, Ernest Bugała, Rafał Jarmakiewicz, Julianna Krasowska, Łukasz Piotrowski
{"title":"Radiation adaptive response: the biophysical phenomenon and its theoretical description.","authors":"Krzysztof W Fornalski, Łukasz Adamowski, Ernest Bugała, Rafał Jarmakiewicz, Julianna Krasowska, Łukasz Piotrowski","doi":"10.1093/rpd/ncae053","DOIUrl":"https://doi.org/10.1093/rpd/ncae053","url":null,"abstract":"<p><p>The radiation adaptive response (or radioadaptation) effect is a biophysical and radiobiological phenomenon responsible for, e.g. the enhancement of repair processes, cell cycle and apoptosis regulation or enhancement of antioxidant production in cells/organisms irradiated by low doses and low dose-rates of ionising radiation. This phenomenon, however, is not always present, which creates many problems both for experimenters and theoreticians. Here we propose a comprehensive and complete theoretical model of radioadaptation grounded in mathematical concept of dose- and time-related probability function of the adaptive response appearance. This can be used in the context of two special cases of the adaptive response: the Raper-Yonezawa (priming dose) effect or constant low-dose-rate irradiation (e.g. for high natural background). This complete theoretical approach is supported by Monte Carlo simulations and real-experimental data used for model calibration and validation.</p>","PeriodicalId":20795,"journal":{"name":"Radiation protection dosimetry","volume":"200 16-18","pages":"1585-1589"},"PeriodicalIF":0.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Should the current radiation protection paradigm and its recommendations be modified to make them more fit to protect the public in future nuclear emergencies?","authors":"James Mc Laughlin","doi":"10.1093/rpd/ncae088","DOIUrl":"10.1093/rpd/ncae088","url":null,"abstract":"<p><p>The present radiation protection paradigm and its associated recommendations as developed by bodies such as the ICRP have performed very well over past decades both for those occupationally exposed to radiation and for the public in planned exposures. There is, however, growing evidence that the role played by this paradigm in the decision-making process to protect the public in nuclear emergencies in the past may have, unwittingly and unintentionally, caused more harm than good to some sections of the public. This seems to have been the case in the use of population evacuation as the principal protection response to the Chernobyl (1986) and Fukushima (2011) accidents. There is thus a need to develop improved guidelines or tools on how to apply radiation protection recommendations for the public compatible with the Principle of Justification in the event of any future major radiation emergencies. It can also be argued that the present radiation protection paradigm, with its emphasis primarily on the physical health detriments from radiation, should be more inclusive and needs to shift to a more holistic or total health approach than heretofore to include mental health effects associated with nuclear emergencies. For severe mental health effects, some of the consequences, such as suicide, can even be as or more severe than most physical detriments likely to be suffered by those affected.</p>","PeriodicalId":20795,"journal":{"name":"Radiation protection dosimetry","volume":"200 16-18","pages":"1501-1506"},"PeriodicalIF":0.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Carbon accumulation model for simulating 14C radioactivity in Chinese yam grown from a seed bulbil.","authors":"Takashi Tani, Ryuji Arai","doi":"10.1093/rpd/ncae026","DOIUrl":"https://doi.org/10.1093/rpd/ncae026","url":null,"abstract":"<p><p>Modeling carbon accumulation in crop plants is key to evaluating the transfer of atmospheric 14C into the edible parts of the plants growing near nuclear facilities. Chinese yam 'Nagaimo' (Dioscorea polystachya Turcz.) is a major crop cultivated near a spent nuclear fuel reprocessing plant in Rokkasho, Aomori, Japan. We developed a dynamic compartment model for assessing carbon and 14C accumulation in Chinese yam grown from a seed bulbil in the field. Light and temperature dependence of leaf photosynthesis and temperature dependence of respiration in leaves, stems and belowground parts (tuber and root) were incorporated into the model. Estimated amounts of carbon in the leaves, stems and belowground parts were good agreement with the measured data from the field. Simulation results of 14C accumulation using this model indicated that the accumulation of 14C in belowground parts at the harvest depends on the rate of photosynthesis on the day of exposure.</p>","PeriodicalId":20795,"journal":{"name":"Radiation protection dosimetry","volume":"200 16-18","pages":"1752-1756"},"PeriodicalIF":0.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of evaluation method for radiocesium availability in soil by biomimetic approach.","authors":"Akira Takeda, Yusuke Unno, Mathew J B Swallow, Yasumi Yagasaki, Tetsuo Yasutaka, Naofumi Akata","doi":"10.1093/rpd/ncae129","DOIUrl":"https://doi.org/10.1093/rpd/ncae129","url":null,"abstract":"<p><p>Applicability of biomimetic approach with simulation of plant uptake for assessment of radiocesium availability in soil was investigated. The soil spiked with 137Cs tracer was contacted with wicking material and copper-substituted prussian blue (Cu-PB), which simulate transpirationally induced mass flow and concentration gradient-induced diffusion of radiocesiumin the soil, respectively. Comparison of the removed 137Cs to the wick and the wick + Cu-PB from the soil during the contact period of 12 weeks suggested that the diffusion process has larger contribution than the mass flow process in radiocesium dynamics in root zone. The change of the removed rate of 137Cs from the soil was reflected that its availability decreased with the time elapsing and with subjecting repeated wet-dry treatment. The results suggest that the biomimetic approach can be applicable to the realistic evaluation of the availability of radiocesium in soil.</p>","PeriodicalId":20795,"journal":{"name":"Radiation protection dosimetry","volume":"200 16-18","pages":"1767-1771"},"PeriodicalIF":0.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of short-term chemical changes in stable ruthenium added to soil by using X-ray absorption fine-structure analysis.","authors":"Yusuke Unno, Akira Takeda","doi":"10.1093/rpd/ncae083","DOIUrl":"https://doi.org/10.1093/rpd/ncae083","url":null,"abstract":"<p><p>Radioactive ruthenium may be accidentally released from spent nuclear fuel reprocessing plants to the surrounding environment. However, research on the chemical behavior of radioactive Ru in the environment is limited, and the complex chemical properties of this element complicate the application of extraction methods for the analyses of its chemical forms. To obtain basic information regarding the outcome of radioactive Ru in the environment, we investigated the changes in the form of stable Ru added to soil through X-ray absorption fine-structure (XAFS) analysis. This study uses ruthenium tetroxide (RuO4), ruthenium dioxide (RuO2), ruthenium nitrosyl nitrate (Ru(NO)(NO3)3) and ruthenium chloride (RuCl3) as test sources. These are added to ultrapure water, soil solution or fresh soil samples, which are analyzed using XAFS immediately or 5 days after Ru addition. The Ru K-edge X-ray absorption near edge structure spectra acquired immediately after Ru addition differed with respect to the source. The XAFS results suggest that RuO4 immediately changes to tetravalent form after deposition from air to soil. For RuCl3, the ionic structure in the vicinity of Ru is affected by the soil even if the valence does not change immediately. By contrast, RuO2 and Ru(NO)(NO3)3 are highly stable in soil. The results show that the chemical forms of RuO2 and Ru(NO)(NO3)3 added to the soil solution and soil are retained for 5 days, whereas those of RuCl3 and RuO4 are affected by the soil solution and soil within a short period. These results emphasize the need to focus on the chemical form of Ru deposits and the form change after Ru addition when investigating the environmental fate of radioactive Ru.</p>","PeriodicalId":20795,"journal":{"name":"Radiation protection dosimetry","volume":"200 16-18","pages":"1744-1747"},"PeriodicalIF":0.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Atmospheric concentrations of 7Be and 210Pb in weekly aerosols at Hirosaki, a heavy snowfall area in Japan.","authors":"Khemruthai Kheamsiri, Oumar Bobbo Modibo, Bagus Sidik Waskito Hadi, Haruka Kuwata, Ryohei Yamada, Chutima Kranrod, Naofumi Akata","doi":"10.1093/rpd/ncae156","DOIUrl":"https://doi.org/10.1093/rpd/ncae156","url":null,"abstract":"<p><p>To understand the regional properties of atmospheric 7Be and 210Pb concentrations at Hirosaki, aerosol samples were collected weekly for the investigation. Total suspended particles (TSP) concentration ranged from 0.14 to 1.19 mg m-3 with a mean value of 0.29 ± 0.08 mg m-3. The activity concentrations during the observation period have shown a similar trend between 7Be and 210Pb, comparable to reported studies. The activity concentrations of 7Be and 210Pb ranged from 0.46 to 4.94 mBq m-3 with an average of 2.22 mBq m-3 and from 0.26 to 1.29 mBq m-3 with an average of 0.64 mBq m-3, respectively. The relation between precipitation and radionuclide concentrations indicated that precipitation is an essential factor in the radionuclide removal process. The rainfall/snowfall had a significant impact on the deposition, and the process was greatly affected by the changes in the features of raindrops and snowflakes, such as intensity, shape, surface area, and falling speed.</p>","PeriodicalId":20795,"journal":{"name":"Radiation protection dosimetry","volume":"200 16-18","pages":"1782-1786"},"PeriodicalIF":0.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}