Open Access Journal of Biomedical Science最新文献_第8页

Psychotropic Medications and Heart 精神药物和心脏

Open Access Journal of Biomedical Science Pub Date : 2022-01-27 DOI: 10.38125/oajbs.000385

A. Wagle

引用次数: 0

"The Effect of Tissue Organization and Homeostasis on Inflammatory Cytoskeletal Signaling in Cancer" 组织组织和稳态对癌症炎症细胞骨架信号传导的影响

Open Access Journal of Biomedical Science Pub Date : 2022-01-26 DOI: 10.38125/oajbs.000384

A. Ahmadi

引用次数: 0

"Origination of Macrocyclic Formazan with Macrocyclic Sulfazan and Triazan as Innovated Compounds and Compared Their efficiency Against Breast Cancer" 《大环甲酰胺与大环磺胺和三嗪的合成及抗乳腺癌效果比较》

Open Access Journal of Biomedical Science Pub Date : 2022-01-25 DOI: 10.38125/oajbs.000383

N. Aljamali

{"title":"\"Origination of Macrocyclic Formazan with Macrocyclic Sulfazan and Triazan as Innovated Compounds and Compared Their efficiency Against Breast Cancer\"","authors":"N. Aljamali","doi":"10.38125/oajbs.000383","DOIUrl":"https://doi.org/10.38125/oajbs.000383","url":null,"abstract":"How to cite this article: Nagham Mahmood A. Origination of Macrocyclic Formazan with Macrocyclic Sulfazan and Triazan as Innovated Compounds and Compared Their efficiency Against Breast Cancer. ABSTRACT Macrocyclic Sulfazan and Macrocyclic Formazan were created and developed globally for the first time by researcher Dr. Nagham Aljamali in April 2021, while same researcher created and innovated Sulfazan compounds as the first time in 2019., Therefore, these compounds considered one of the developed and modern compounds which have a lack of references or scarcity of books and researches. Therefore, the researcher, Dr. Nagham prepared and created a chain of these innovated compounds and studied by numerous applications, containing biological, pharmaceutical studies, also as antifungal, antibacterial, anticancer agents, and here in this research, also cyclic sulfazan and cyclic formazan were studied a several applications. A numeral of practical spectroscopic studies has been used to exhibit their chemical structures which provided strong evidence of their chemical structures through various technical devices like (FT IR-Spectra, 1H.NMR-Spectra, Mass-Spectra)., Melting points, other studies represented by evolution them as bio-compounds by scanning them as anticancer compounds.","PeriodicalId":207626,"journal":{"name":"Open Access Journal of Biomedical Science","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132422007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

"Genetic Contribution and Inhibitor Marker of Diabetic Disease: A Review Article" 糖尿病的遗传贡献与抑制标志物研究综述

Open Access Journal of Biomedical Science Pub Date : 2022-01-24 DOI: 10.38125/oajbs.000382

Nanda Rachmad Putra Gofur

{"title":"\"Genetic Contribution and Inhibitor Marker of Diabetic Disease: A Review Article\"","authors":"Nanda Rachmad Putra Gofur","doi":"10.38125/oajbs.000382","DOIUrl":"https://doi.org/10.38125/oajbs.000382","url":null,"abstract":": Currently available glucose-lowering therapies target one or more of the treatment pathways. The patient approach should be used for multiple pharmacological options. Factors to consider include efficacy, cost, potential side effects, weight gain, comorbidities, risk of hypoglycemia, and patient preference. Pharmacological treatment should be initiated when glycemic control is not achieved or if HbA1C increases to 6.5% after 2-3 months of lifestyle intervention. Discussion : Therapy with oral medication should be started in conjunction with intensive lifestyle management. The major classes of oral antidiabetic drugs include biguanides, sulfonylureas, meglitinides, thiazolidinedione (TZD) inhibitors, dipeptidyl peptidase 4 (DPP-4), sodium-glucose cotransporter (SGLT2) inhibitors, and -glucosidase inhibitors. If the HbA1C level increases to 7.5% during treatment or if the baseline HbA1C is 9%, combination therapy with two oral agents, or with insulin, may be an option. Although this drug can be used in all patients regardless of their weight, some drugs such as liraglutide may have distinct advantages in obese patients compared to lean diabetics. Conclusion : Inhibitors is for patients not receiving an intensive insulin regimen. According to current guidelines, HbA1C levels should be assessed regularly in all diabetic patients. The frequency of HbA1C testing is flexible and depends primarily on the patient’s response to therapy and the physician’s judgment. HbA1C testing is performed at least every 6 months for patients who are meeting treatment goals.","PeriodicalId":207626,"journal":{"name":"Open Access Journal of Biomedical Science","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122005560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

"Unusual Low-Grade Spindle Cell Sarcoma Pattern of Dedifferentiation Occurring in Chondrosarcoma: A Case Report" 软骨肉瘤发生异常低级别梭形细胞型去分化1例

Open Access Journal of Biomedical Science Pub Date : 2022-01-20 DOI: 10.38125/oajbs.000380

Christopher John Wilson

引用次数: 0

Conditions Associated with Type 3 Chlorine Channels (ClC-3) 3类氯通道(ClC-3)的相关条件

Open Access Journal of Biomedical Science Pub Date : 2022-01-19 DOI: 10.38125/oajbs.000379

Claudia Mancilla Simbro

引用次数: 0

Analgesic Potential Sodium Channel SCN9A 镇痛电位钠通道SCN9A

Open Access Journal of Biomedical Science Pub Date : 2022-01-18 DOI: 10.38125/oajbs.000378

Claudia Mancilla Simbro

引用次数: 0

Factors Determining Meat Quality and Cold Preservation Methods to Extend Shelf Life 决定肉类品质的因素和延长保质期的冷藏方法

Open Access Journal of Biomedical Science Pub Date : 2022-01-12 DOI: 10.38125/oajbs.000377

Reinaldo Letelier Contreras

{"title":"Factors Determining Meat Quality and Cold Preservation Methods to Extend Shelf Life","authors":"Reinaldo Letelier Contreras","doi":"10.38125/oajbs.000377","DOIUrl":"https://doi.org/10.38125/oajbs.000377","url":null,"abstract":"Meat refers to animal tissues that can be used as food, its main component being skeletal muscle with some degree of fat and connective tissue. Since the early 1980s, the production, consumption and world trade of meat has increased considerably and these changes are related to world population growth, urbanization and rising domestic incomes in developing countries, as well as changes in consumption patterns, which trigger a global increase in demand for food of animal origin. In general terms, “quality” can be defined as the extent to which a product or service meets consumer expectations over time. When referred to meat quality, it focuses on hygienic aspects during its production, to its nutritional value or to the organoleptic or technological characteristics. The conservation of food implies the action to keep it with the properties or desired nature for as long as possible. The application of cold in meat, as the most used method for its conservation, is mainly due to two purposes: to preserve the initial food quality, with a view to its consumption, and to keep it at an adequate temperature for its maturation and the chemical and biochemical reactions that determine its quality and shelf life. The shelf life of food can be defined as the maximum time in which food maintains its nutritional, sensory, microbiological and safety qualities at levels accepted by consumers. Refrigeration and freezing are the most used traditional methods to preserve meat, based on the application of cold to the carcasses. The main objective is to avoid decomposition due to bacterial alteration.","PeriodicalId":207626,"journal":{"name":"Open Access Journal of Biomedical Science","volume":"140 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134193014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibiotic Resistance of Pseudomonas aeruginosa Chronic Infection in Cystic Fibrosis Patients. A SingleCenter Long-Term Follow-Up 囊性纤维化患者铜绿假单胞菌慢性感染的耐药性分析。单中心长期随访

Open Access Journal of Biomedical Science Pub Date : 2022-01-11 DOI: 10.38125/oajbs.000376

E. Berghea

{"title":"Antibiotic Resistance of Pseudomonas aeruginosa Chronic Infection in Cystic Fibrosis Patients. A SingleCenter Long-Term Follow-Up","authors":"E. Berghea","doi":"10.38125/oajbs.000376","DOIUrl":"https://doi.org/10.38125/oajbs.000376","url":null,"abstract":"Pseudomonas aeruginosa is the major bacterial pathogen associated with increased mortality and morbidity in cystic fibrosis patients. This study compared the antimicrobial susceptibilities of 56 Pseudomonas aeruginosa isolates collected from 28 Romanian pediatric patients over 15 years (2005-2020) and investigated the resistance to the usual antibiotics and the incidence of multidrug resistance Pseudomonas aeruginosa . The susceptibility rates to antimicrobials were as follows: Gentamicin 50%; Cefepime 53.6%; Ceftazidime 64.3%; Amikacin 67.9%; Ciprofloxacin 75%; Piperacillin 75%; Piperacillin-Tazobactam 82.1%; Meropenem 82.1% Levofloxacin 89.3%; Colistin 100%. Half of the patients gain antibiotic resistance during the study period. We noticed the most significant increase in antibiotic resistance for Ciprofloxacin, 14.3%, followed by Meropenem 10.8%, Ceftazidime 10.7%, and Piperacillin 10.7%. Multi-drug resistance Pseudomonas aeruginosa strains were identified with a frequency of 25% of 56 samples. 28.5% of patients with multi-drug resistance Pseudomonas aeruginosa strains were identified. Only one patient meets the criteria and can be classified as extensively drug-resistant Pseudomonas aeruginosa , sensitive only to Colistin. New therapeutic strategies for the treatment of Pseudomonas aeruginosa infections are an immediate necessity.","PeriodicalId":207626,"journal":{"name":"Open Access Journal of Biomedical Science","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124942072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

"Development Plan for the Project: Integrated System for Patient Localization, Tracking and Monitoring in an Indoor Environment" "项目开发计划：室内环境中病人定位、跟踪和监测综合系统"

Open Access Journal of Biomedical Science Pub Date : 2022-01-10 DOI: 10.38125/oajbs.000375

L. Bibbò

引用次数: 0