{"title":"软骨肉瘤发生异常低级别梭形细胞型去分化1例","authors":"Christopher John Wilson","doi":"10.38125/oajbs.000380","DOIUrl":null,"url":null,"abstract":"Chondrosarcoma is a cartilage forming tumour, typically found in flat bones such as the ilium. It is known to have a male preponderance and encountered in the older age group. The lesions are locally aggressive, and onset of symptoms is gradual. Dedifferentiated chondrosarcoma typically has 2 microscopic components, whereby the low-grade cartilaginous lesion is seen with a high grade sarcomatous component with an abrupt transition between the 2 zones [1]. This pattern of dedifferentiation occurs in about 10% of chondrosarcomas [2,3]. The femur is involved in about 30% of these lesions and majority of the tumors are seen beyond the sixth decade [1]. We report an unusual pattern of dedifferentiation occurring in a chondrosarcoma where the pattern of dedifferentiation was that of a low-grade spindle cell sarcoma.","PeriodicalId":207626,"journal":{"name":"Open Access Journal of Biomedical Science","volume":"27 9 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"\\\"Unusual Low-Grade Spindle Cell Sarcoma Pattern of Dedifferentiation Occurring in Chondrosarcoma: A Case Report\\\"\",\"authors\":\"Christopher John Wilson\",\"doi\":\"10.38125/oajbs.000380\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Chondrosarcoma is a cartilage forming tumour, typically found in flat bones such as the ilium. It is known to have a male preponderance and encountered in the older age group. The lesions are locally aggressive, and onset of symptoms is gradual. Dedifferentiated chondrosarcoma typically has 2 microscopic components, whereby the low-grade cartilaginous lesion is seen with a high grade sarcomatous component with an abrupt transition between the 2 zones [1]. This pattern of dedifferentiation occurs in about 10% of chondrosarcomas [2,3]. The femur is involved in about 30% of these lesions and majority of the tumors are seen beyond the sixth decade [1]. We report an unusual pattern of dedifferentiation occurring in a chondrosarcoma where the pattern of dedifferentiation was that of a low-grade spindle cell sarcoma.\",\"PeriodicalId\":207626,\"journal\":{\"name\":\"Open Access Journal of Biomedical Science\",\"volume\":\"27 9 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Access Journal of Biomedical Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.38125/oajbs.000380\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Access Journal of Biomedical Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.38125/oajbs.000380","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
"Unusual Low-Grade Spindle Cell Sarcoma Pattern of Dedifferentiation Occurring in Chondrosarcoma: A Case Report"
Chondrosarcoma is a cartilage forming tumour, typically found in flat bones such as the ilium. It is known to have a male preponderance and encountered in the older age group. The lesions are locally aggressive, and onset of symptoms is gradual. Dedifferentiated chondrosarcoma typically has 2 microscopic components, whereby the low-grade cartilaginous lesion is seen with a high grade sarcomatous component with an abrupt transition between the 2 zones [1]. This pattern of dedifferentiation occurs in about 10% of chondrosarcomas [2,3]. The femur is involved in about 30% of these lesions and majority of the tumors are seen beyond the sixth decade [1]. We report an unusual pattern of dedifferentiation occurring in a chondrosarcoma where the pattern of dedifferentiation was that of a low-grade spindle cell sarcoma.