Proceedings of the Japan Academy. Series B, Physical and Biological Sciences最新文献_第2页

Performance comparison of complementary relationship and inverse analysis methods for evapotranspiration estimation. 互补关系与逆分析方法在蒸散估算中的性能比较。

IF 4.6 3区综合性期刊

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences Pub Date : 2025-01-01 DOI: 10.2183/pjab.101.028

Toshisuke Maruyama, Manabu Segawa, Hiroshi Takimoto

{"title":"Performance comparison of complementary relationship and inverse analysis methods for evapotranspiration estimation.","authors":"Toshisuke Maruyama, Manabu Segawa, Hiroshi Takimoto","doi":"10.2183/pjab.101.028","DOIUrl":"https://doi.org/10.2183/pjab.101.028","url":null,"abstract":"Evapotranspiration is a critical factor that plays a pivotal role in irrigation and water resource planning. It is also a major influence with regard to global warming issues. Therefore, several studies have been performed on the estimation methods for evapotranspiration; however, the most prevalent method used over a long period to estimate evapotranspiration is the complementary relationship approach. Recently, this method was modified to improve its symmetry and accuracy. However, to achieve better performance, a different evapotranspiration estimation method using an inverse analysis of the Bowen ratio was proposed by us in an earlier study. In order to present a performance comparison of these different estimation methods, the reproducibility of three types of complementary relationship methods and inverse analysis methods was assessed in this study. Our study utilized data from FLUXNET2015 and evaluated the performance of the methods using regression analysis and root mean square error (RMSE) with data from 15 test sites, mainly located in the U.S.A., for a total period of 132 years. From the results, it was observed that the inverse analysis approach demonstrated a slightly better performance than the complementary relationship methods. This study provides a valuable direction for future research works on the estimation of evapotranspiration.","PeriodicalId":20707,"journal":{"name":"Proceedings of the Japan Academy. Series B, Physical and Biological Sciences","volume":"101 8","pages":"485-509"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemical biology research in RIKEN NPDepo aimed at agricultural applications. 理化学研究所 NPDepo 以农业应用为目标的化学生物学研究。

IF 4.4 3区综合性期刊

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences Pub Date : 2025-01-01 DOI: 10.2183/pjab.101.003

Hiroyuki Osada

{"title":"Chemical biology research in RIKEN NPDepo aimed at agricultural applications.","authors":"Hiroyuki Osada","doi":"10.2183/pjab.101.003","DOIUrl":"10.2183/pjab.101.003","url":null,"abstract":"This review outlines research on chemical biology using mainly microbial metabolites for agricultural applications. We established the RIKEN Natural Products Depository (NPDepo), housing many microbial metabolites, to support academic researchers who focus on drug discovery. We studied methods to stimulate secondary metabolism in microorganisms to collect various microbial products. The switch of secondary metabolism in microorganisms changes depending on the culture conditions. We discovered compounds that activate biosynthetic gene clusters in actinomycetes and filamentous fungi. Using these compounds, we succeeded in inducing the production of active compounds. Two approaches for screening bioactive compounds are described. One is phenotypic screening to explore antifungal compounds assisted by artificial intelligence (AI). AI can distinguish the morphological changes induced by antifungal compounds in filamentous fungi. The other is the chemical array method for detecting interactions between compounds and target proteins. Our chemical biology approach yielded many new compounds as fungicide candidates.","PeriodicalId":20707,"journal":{"name":"Proceedings of the Japan Academy. Series B, Physical and Biological Sciences","volume":"101 1","pages":"8-31"},"PeriodicalIF":4.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142979771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanisms of autophagosome formation. 自噬体的形成机制

IF 4.4 3区综合性期刊

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences Pub Date : 2025-01-01 DOI: 10.2183/pjab.101.005

Yuko Fujioka, Nobuo N. Noda

引用次数: 0

Pursuing the identity of a natural medicine licorice by Dr. Shoji Shibata that he firstly investigated half a century before. 寻找柴田正二博士在半个世纪前首次研究的天然药物甘草的身份。

IF 4.6 3区综合性期刊

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences Pub Date : 2025-01-01 DOI: 10.2183/pjab.101.018

Michiho Ito

引用次数: 0

Multi-region processing during sleep for memory and cognition. 睡眠中记忆和认知的多区域加工。

IF 4.6 3区综合性期刊

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences Pub Date : 2025-01-01 DOI: 10.2183/pjab.101.008

Salma E Said, Daisuke Miyamoto

{"title":"Multi-region processing during sleep for memory and cognition.","authors":"Salma E Said, Daisuke Miyamoto","doi":"10.2183/pjab.101.008","DOIUrl":"10.2183/pjab.101.008","url":null,"abstract":"Over the past decades, the understanding of sleep has evolved to be a fundamental physiological mechanism integral to the processing of different types of memory rather than just being a passive brain state. The cyclic sleep substates, namely, rapid eye movement (REM) sleep and non-REM (NREM) sleep, exhibit distinct yet complementary oscillatory patterns that form inter-regional networks between different brain regions crucial to learning, memory consolidation, and memory retrieval. Technical advancements in imaging and manipulation approaches have provided deeper understanding of memory formation processes on multi-scales including brain-wide, synaptic, and molecular levels. The present review provides a short background and outlines the current state of research and future perspectives in understanding the role of sleep and its substates in memory processing from both humans and rodents, with a focus on cross-regional brain communication, oscillation coupling, offline reactivations, and engram studies. Moreover, we briefly discuss how sleep contributes to other higher-order cognitive functions.","PeriodicalId":20707,"journal":{"name":"Proceedings of the Japan Academy. Series B, Physical and Biological Sciences","volume":"101 3","pages":"107-128"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143616925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Common and distinct features of diverse macrophage populations in the central nervous system. 中枢神经系统中不同巨噬细胞群的共同和独特特征。

IF 4.6 3区综合性期刊

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences Pub Date : 2025-01-01 DOI: 10.2183/pjab.101.013

Takahiro Masuda

引用次数: 0

Cellular senescence as a source of chronic microinflammation that promotes the aging process. 细胞衰老是促进衰老过程的慢性微炎症的来源。

IF 4.6 3区综合性期刊

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences Pub Date : 2025-01-01 DOI: 10.2183/pjab.101.014

Makoto Nakanishi

{"title":"Cellular senescence as a source of chronic microinflammation that promotes the aging process.","authors":"Makoto Nakanishi","doi":"10.2183/pjab.101.014","DOIUrl":"10.2183/pjab.101.014","url":null,"abstract":"Why and how do we age? This physiological phenomenon that we all experience remains a great mystery, largely unexplained even in this age of scientific and technological progress. Aging is a significant risk factor for numerous diseases, including cancer. However, underlying mechanisms responsible for this association remain to be elucidated. Recent findings have elucidated the significance of the accumulation of senescent cells and other inflammatory cells in organs and tissues with age, and their deleterious effects, such as the induction of inflammation in the microenvironment, as underlying factors contributing to organ dysfunction and disease development. Cellular senescence is a cellular phenomenon characterized by a permanent cessation of cell proliferation and secretion of several proinflammatory cytokines (senescence associated secretory phenotypes). Notably, the elimination of senescent cells from aging individuals has been demonstrated to alleviate age-related organ and tissue dysfunction, as well as various geriatric diseases. This review summarizes the molecular mechanisms by which senescent cells are induced and contribute to age-related diseases, as well as the technologies that ameliorate them.","PeriodicalId":20707,"journal":{"name":"Proceedings of the Japan Academy. Series B, Physical and Biological Sciences","volume":"101 4","pages":"224-237"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular basis of individual locomotor function: Integrated understanding of gene expression regulation in the development and homeostasis of the musculoskeletal system. 个体运动功能的分子基础：对肌肉骨骼系统发育和动态平衡中基因表达调控的综合理解。

IF 4.6 3区综合性期刊

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences Pub Date : 2025-01-01 DOI: 10.2183/pjab.101.027

Hiroshi Asahara

{"title":"Molecular basis of individual locomotor function: Integrated understanding of gene expression regulation in the development and homeostasis of the musculoskeletal system.","authors":"Hiroshi Asahara","doi":"10.2183/pjab.101.027","DOIUrl":"10.2183/pjab.101.027","url":null,"abstract":"This review examines the molecular mechanisms controlling the development and homeostasis of the musculoskeletal system through gene expression regulation. It introduces key discoveries from basic transcriptional control to advanced mechanotransduction pathways, focusing on our contributions including the EMBRYS database for transcription factor expression analysis and the identification of RP58 in muscle development and Mohawk (Mkx) in tendon formation. We also elucidated the role of miR-140 as a critical regulator in cartilage development and homeostasis. This microRNA is specifically expressed in cartilage, promotes chondrogenesis, and is involved in protective mechanisms against cartilage degenerative diseases such as osteoarthritis. Our discovery of the PIEZO1-Mkx pathway provides a molecular mechanism linking mechanical stimuli to gene expression in tendons, explaining tissue adaptation and differences in motor abilities. Understanding these pathways offers new therapeutic strategies for tendon and ligament injuries, age-related decline, and cartilage diseases. Currently, we are proposing the concept of \"tenopenia\" to complement sarcopenia, addressing the mechanisms of age-related tendon deterioration. This integrated approach to the musculoskeletal system as an environment-responsive entity advances both fundamental science and clinical applications aimed at maintaining mobility throughout life.","PeriodicalId":20707,"journal":{"name":"Proceedings of the Japan Academy. Series B, Physical and Biological Sciences","volume":"101 7","pages":"373-393"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12463553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toward structural understanding of eukaryotic transcription elongation. 真核生物转录延伸的结构理解。

IF 4.6 3区综合性期刊

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences Pub Date : 2025-01-01 DOI: 10.2183/pjab.101.024

Shun-Ichi Sekine

引用次数: 0

Correction to "Dynamics of the nucleoside diphosphate kinase protein DYNAMO2 correlates with the changes in the global GTP level during the cell cycle of Cyanidioschyzon merolae". 更正“核苷二磷酸激酶蛋白DYNAMO2的动力学与Cyanidioschyzon merolae细胞周期中全球GTP水平的变化相关”。

IF 4.6 3区综合性期刊

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences Pub Date : 2025-01-01 DOI: 10.2183/pjab.101.022

Yuuta Imoto, Yuichi Abe, Kanji Okumoto, Mio Ohnuma, Haruko Kuroiwa, Tsuneyoshi Kuroiwa, Yukio Fujiki

引用次数: 0