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Probiotics and Antimicrobial Proteins最新文献

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Probiotic Potential, Safety, and Technological Attributes of Lactiplantibacillus plantarum R2: Potent Antibiofilm and Cytotoxic Efficacy. 植物乳杆菌R2的益生菌潜力、安全性和技术特性：有效的抗生素膜和细胞毒性功效。
IF 4.4 2区 生物学
Probiotics and Antimicrobial Proteins Pub Date : 2026-04-29 DOI: 10.1007/s12602-026-11015-9
Parisa Ghasemi, Behrooz Alizadeh Behbahani, Mohammad Noshad, Zahra Nikfarjam, Alireza Vasiee
{"title":"Probiotic Potential, Safety, and Technological Attributes of Lactiplantibacillus plantarum R2: Potent Antibiofilm and Cytotoxic Efficacy.","authors":"Parisa Ghasemi, Behrooz Alizadeh Behbahani, Mohammad Noshad, Zahra Nikfarjam, Alireza Vasiee","doi":"10.1007/s12602-026-11015-9","DOIUrl":"https://doi.org/10.1007/s12602-026-11015-9","url":null,"abstract":"","PeriodicalId":20506,"journal":{"name":"Probiotics and Antimicrobial Proteins","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Characterization and Antifungal Efficacy of NJ-62 Protein from Weizmannia coagulans CGMCC 9951 against Ceratocystis fimbriata. 凝固魏氏菌CGMCC 9951 NJ-62蛋白对毛状角鼻虫的抑菌活性研究
IF 4.4 2区 生物学
Probiotics and Antimicrobial Proteins Pub Date : 2026-04-28 DOI: 10.1007/s12602-026-11037-3
Jia Xu, Xiaohan Liu, Xin Li, Ying Wu, Pengyan Li, Shanshan Tie, Pingping Tian, Shaobin Gu
{"title":"The Characterization and Antifungal Efficacy of NJ-62 Protein from Weizmannia coagulans CGMCC 9951 against Ceratocystis fimbriata.","authors":"Jia Xu, Xiaohan Liu, Xin Li, Ying Wu, Pengyan Li, Shanshan Tie, Pingping Tian, Shaobin Gu","doi":"10.1007/s12602-026-11037-3","DOIUrl":"https://doi.org/10.1007/s12602-026-11037-3","url":null,"abstract":"","PeriodicalId":20506,"journal":{"name":"Probiotics and Antimicrobial Proteins","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive Genomic Characterization and Probiotic Properties Evaluation of Limosilactobacillus fermentum JAC 231 Isolated from Vaginal Microbiota. 阴道菌群发酵乳酸杆菌JAC 231的综合基因组鉴定和益生菌特性评价
IF 4.4 2区 生物学
Probiotics and Antimicrobial Proteins Pub Date : 2026-04-28 DOI: 10.1007/s12602-026-11025-7
Carmem Duarte Lima Campos, Amanda Graziella Goncalves Mendes, José Lima Pereira-Filho, Viviane da Silva Sousa Almeida, Ana Beatriz Santos Sousa, Israel Viegas Moreira, João Lucas do Carmo Lima, Aleania Polassa Almeida Pereira, Allysson Kayron Carvalho Silva, Laís Araújo Souza Wolff, Kátia Regina Assunção Borges, Cristianne Roberta Rhoden, Cinara Regina Aragão Vieira Monteiro, Cristina de Andrade Monteiro, Elizabeth Soares Fernandes, Valério Monteiro-Neto
{"title":"Comprehensive Genomic Characterization and Probiotic Properties Evaluation of Limosilactobacillus fermentum JAC 231 Isolated from Vaginal Microbiota.","authors":"Carmem Duarte Lima Campos, Amanda Graziella Goncalves Mendes, José Lima Pereira-Filho, Viviane da Silva Sousa Almeida, Ana Beatriz Santos Sousa, Israel Viegas Moreira, João Lucas do Carmo Lima, Aleania Polassa Almeida Pereira, Allysson Kayron Carvalho Silva, Laís Araújo Souza Wolff, Kátia Regina Assunção Borges, Cristianne Roberta Rhoden, Cinara Regina Aragão Vieira Monteiro, Cristina de Andrade Monteiro, Elizabeth Soares Fernandes, Valério Monteiro-Neto","doi":"10.1007/s12602-026-11025-7","DOIUrl":"https://doi.org/10.1007/s12602-026-11025-7","url":null,"abstract":"","PeriodicalId":20506,"journal":{"name":"Probiotics and Antimicrobial Proteins","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bifidobacterium animalis subsp. lactis and Enterococcus hirae Enhance Immunity by Modulating Gut Microbiota and Metabolic Pathways in Immunosuppressed Mice. 动物双歧杆菌亚种。乳酸菌和霍乱肠球菌通过调节免疫抑制小鼠肠道菌群和代谢途径增强免疫。
IF 4.4 2区 生物学
Probiotics and Antimicrobial Proteins Pub Date : 2026-04-27 DOI: 10.1007/s12602-026-11020-y
Azmat Ullah Jan, Hu Chen, Muhammad Ishaq, Mengya Jia, Ali Sher Bacha, Qiang Li, Mengyan Chen, Zitong Ding, Xusheng Guo
{"title":"Bifidobacterium animalis subsp. lactis and Enterococcus hirae Enhance Immunity by Modulating Gut Microbiota and Metabolic Pathways in Immunosuppressed Mice.","authors":"Azmat Ullah Jan, Hu Chen, Muhammad Ishaq, Mengya Jia, Ali Sher Bacha, Qiang Li, Mengyan Chen, Zitong Ding, Xusheng Guo","doi":"10.1007/s12602-026-11020-y","DOIUrl":"https://doi.org/10.1007/s12602-026-11020-y","url":null,"abstract":"","PeriodicalId":20506,"journal":{"name":"Probiotics and Antimicrobial Proteins","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioactive Peptides from Bovine Colostrum: Sources, Structures, and Biomedical Applications. 牛初乳生物活性肽：来源、结构和生物医学应用。
IF 4.4 2区 生物学
Probiotics and Antimicrobial Proteins Pub Date : 2026-04-25 DOI: 10.1007/s12602-026-10998-9
Yağız Alkan, Yalçın Mert Yalçıntaş, Sercan Karav
{"title":"Bioactive Peptides from Bovine Colostrum: Sources, Structures, and Biomedical Applications.","authors":"Yağız Alkan, Yalçın Mert Yalçıntaş, Sercan Karav","doi":"10.1007/s12602-026-10998-9","DOIUrl":"https://doi.org/10.1007/s12602-026-10998-9","url":null,"abstract":"","PeriodicalId":20506,"journal":{"name":"Probiotics and Antimicrobial Proteins","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic Categorization and Functional Diversity of Secondary Metabolites from Bacillus spp.: A Review. 芽孢杆菌次生代谢物的系统分类与功能多样性研究进展
IF 4.4 2区 生物学
Probiotics and Antimicrobial Proteins Pub Date : 2026-04-24 DOI: 10.1007/s12602-026-11007-9
Yihan Lv, Huanxu Sun, Tajin Wang, Xinyue Wang, Haipeng Zhang, Hongxia Ma
{"title":"Systematic Categorization and Functional Diversity of Secondary Metabolites from Bacillus spp.: A Review.","authors":"Yihan Lv, Huanxu Sun, Tajin Wang, Xinyue Wang, Haipeng Zhang, Hongxia Ma","doi":"10.1007/s12602-026-11007-9","DOIUrl":"https://doi.org/10.1007/s12602-026-11007-9","url":null,"abstract":"<p><p>Microbial secondary metabolites shape interactions across agricultural, food, and clinical settings, and many have seeded modern antimicrobial discovery. Bacillus species are particularly prolific producers, encoding biosynthetic systems that generate chemically diverse metabolite families, ranging from lipopeptides and peptides to macrolactones, organic acids, polyketides, and squalenes with activities that extend beyond growth inhibition to antibiofilm effects, signaling, and host-relevant phenotypes. Here we systematically categorize Bacillus-derived secondary metabolites based on biosynthetic logic and chemical scaffolds, synthesize current understanding of their modes of action, and highlight representative structure-function relationships that explain potency, spectrum, and context dependence. We further discuss practical considerations that constrain translation, including metabolite heterogeneity in complex mixtures, yield and manufacturability, cytotoxicity and stability, and challenges in assigning causality to specific compounds in vivo. Finally, we outline emerging opportunities leveraging genome mining, metabolomics-enabled dereplication, and synthetic biology. These approaches allow for the prioritization of promising metabolites and the tailoring of their deployment across agriculture, food systems, and medicine. By linking chemical architecture to biological function, this review provides a framework for rational selection and application of Bacillus metabolites in diverse applied contexts.</p>","PeriodicalId":20506,"journal":{"name":"Probiotics and Antimicrobial Proteins","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cordyceps Militaris Exopolysaccharides and Lactiplantibacillus Plantarum H8 Synergistically Improve Immune Function Damage in Cyclophosphamide-Induced Immunosuppressed Mice. 蛹虫草外多糖和植物乳杆菌H8协同改善环磷酰胺诱导免疫抑制小鼠免疫功能损伤
IF 4.4 2区 生物学
Probiotics and Antimicrobial Proteins Pub Date : 2026-04-24 DOI: 10.1007/s12602-026-11023-9
Jingjing Xuan, Shengdong Bao, Lidan Guo, Bin Jiang, Ji Wang, Dayong Ren
{"title":"Cordyceps Militaris Exopolysaccharides and Lactiplantibacillus Plantarum H8 Synergistically Improve Immune Function Damage in Cyclophosphamide-Induced Immunosuppressed Mice.","authors":"Jingjing Xuan, Shengdong Bao, Lidan Guo, Bin Jiang, Ji Wang, Dayong Ren","doi":"10.1007/s12602-026-11023-9","DOIUrl":"https://doi.org/10.1007/s12602-026-11023-9","url":null,"abstract":"","PeriodicalId":20506,"journal":{"name":"Probiotics and Antimicrobial Proteins","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Benefits of Lactic Acid Bacteria Folate Synthesis in Foods and Risks Associated with Deficiency - a Review. 乳酸菌在食品中合成叶酸的益处和缺乏叶酸的风险综述。
IF 4.4 2区 生物学
Probiotics and Antimicrobial Proteins Pub Date : 2026-04-24 DOI: 10.1007/s12602-026-11018-6
Maria Fernanda Fernandes Siqueira, Khadija Bezerra Massaut, Patrícia Bohmer Radatz, Silvana de Souza Sigali, Igor Henrique de Lima Costa, Pedro Fernandes Viana, Graciela Volz Lopes, Wladimir Padilha da Silva, Ângela Maria Fiorentini
{"title":"Benefits of Lactic Acid Bacteria Folate Synthesis in Foods and Risks Associated with Deficiency - a Review.","authors":"Maria Fernanda Fernandes Siqueira, Khadija Bezerra Massaut, Patrícia Bohmer Radatz, Silvana de Souza Sigali, Igor Henrique de Lima Costa, Pedro Fernandes Viana, Graciela Volz Lopes, Wladimir Padilha da Silva, Ângela Maria Fiorentini","doi":"10.1007/s12602-026-11018-6","DOIUrl":"https://doi.org/10.1007/s12602-026-11018-6","url":null,"abstract":"","PeriodicalId":20506,"journal":{"name":"Probiotics and Antimicrobial Proteins","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Marine Polysaccharides: A Promising Source for Probiotic Delivery Systems. 海洋多糖：益生菌输送系统的一个有前途的来源。
IF 4.4 2区 生物学
Probiotics and Antimicrobial Proteins Pub Date : 2026-04-23 DOI: 10.1007/s12602-026-11030-w
Sathish Kumar Venkatachalam, Shantkriti Srinivasan, Murali Santhoshkumar, Nallusamy Duraisamy, Ramachandran Vinayagam, Dharmaraj Senthilkumar
{"title":"Marine Polysaccharides: A Promising Source for Probiotic Delivery Systems.","authors":"Sathish Kumar Venkatachalam, Shantkriti Srinivasan, Murali Santhoshkumar, Nallusamy Duraisamy, Ramachandran Vinayagam, Dharmaraj Senthilkumar","doi":"10.1007/s12602-026-11030-w","DOIUrl":"https://doi.org/10.1007/s12602-026-11030-w","url":null,"abstract":"","PeriodicalId":20506,"journal":{"name":"Probiotics and Antimicrobial Proteins","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gene Exchange Mechanisms in Natural and Engineered Probiotics Within the Human Gut Implications for Antibiotic Resistance and Metabolic Modulation. 人类肠道内天然和工程益生菌的基因交换机制对抗生素耐药性和代谢调节的影响。
IF 4.4 2区 生物学
Probiotics and Antimicrobial Proteins Pub Date : 2026-04-22 DOI: 10.1007/s12602-026-11029-3
Harsh V Purohit, Joydeep Chakraborty, Ramesh K Kothari, Amishi R Bhatt
{"title":"Gene Exchange Mechanisms in Natural and Engineered Probiotics Within the Human Gut Implications for Antibiotic Resistance and Metabolic Modulation.","authors":"Harsh V Purohit, Joydeep Chakraborty, Ramesh K Kothari, Amishi R Bhatt","doi":"10.1007/s12602-026-11029-3","DOIUrl":"https://doi.org/10.1007/s12602-026-11029-3","url":null,"abstract":"","PeriodicalId":20506,"journal":{"name":"Probiotics and Antimicrobial Proteins","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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